Journal of Psychosomatic Research最新文献

{"title":"Diagnostic accuracy and practical utility of depression screening questionnaires across renal replacement therapy modalities","authors":"Isabel Vázquez ,&nbsp;Lorena García-Becerra ,&nbsp;Jesús Calviño ,&nbsp;Pablo Bouza ,&nbsp;Pablo Otero-Alonso ,&nbsp;Mª. Dolores Arza ,&nbsp;Ángel Salgado","doi":"10.1016/j.jpsychores.2026.112555","DOIUrl":"10.1016/j.jpsychores.2026.112555","url":null,"abstract":"<div><h3>Background</h3><div>Depression is common yet underdiagnosed in patients receiving renal replacement therapies (RRT). Several questionnaires have shown utility for depression screening, mainly among in-centre haemodialysis patients; however, no instruments have been evaluated for diagnostic accuracy in home dialysis or kidney transplant populations. This study aimed to assess the diagnostic performance of the Beck Depression Inventory–Second Edition (BDI-II), the Beck Depression Inventory–Fast Screen (BDI-FS), and the Depression Subscale of the Hospital Anxiety and Depression Scale (HADS-D) across RRT modalities and to identify the most efficient tool for clinical use.</div></div><div><h3>Methods</h3><div>Adult patients across RRT modalities completed the BDI-II, BDI-FS, and HADS-D, and were evaluated with the Structured Clinical Interview as the reference standard.</div></div><div><h3>Results</h3><div>Among the 203 included patients (mean age 67.3 years; 65% male), 18.2% met SCID-I criteria for depression. Optimal cut-offs were BDI-II ≥15 for in-centre haemodialysis and ≥ 16 for home dialysis and transplantation; BDI-FS ≥3 for in-centre and home dialysis and ≥ 4 for transplantation; and HADS-D ≥ 5 for in-centre haemodialysis and ≥ 6 for home dialysis and transplantation. Sensitivity and negative predictive values exceeded 90% for all instruments except the HADS-D, which showed lower sensitivity in transplanted (86.7%) and home dialysis patients (70%).</div></div><div><h3>Conclusions</h3><div>The BDI-II, BDI-FS, and HADS-D are useful for depression screening in renal populations, though the HADS-D demonstrated reduced performance in home dialysis. Standard cut-offs were inadequate, and modality-specific thresholds improved diagnostic accuracy. The BDI-FS, combining strong accuracy with brevity and ease of use, emerged as the most efficient tool for routine screening across RRT modalities.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112555"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fibromyalgia and its psychosocial determinants in mothers of children with attention-deficit/hyperactivity disorder: A controlled cross-sectional study","authors":"Halenur Teke ,&nbsp;Abdulbaki Artik ,&nbsp;Bahar Oztelcan Gunduz ,&nbsp;Cansel Azizagaoglu ,&nbsp;Kazim Kutluturk ,&nbsp;Nuran Erden ,&nbsp;Erman Atas ,&nbsp;Mehmet Ayhan Congologlu","doi":"10.1016/j.jpsychores.2026.112561","DOIUrl":"10.1016/j.jpsychores.2026.112561","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the prevalence of fibromyalgia (FM) and its psychosocial correlates in mothers of children diagnosed with attention-deficit/hyperactivity disorder (ADHD), compared with mothers of healthy peers.</div></div><div><h3>Methods</h3><div>This controlled cross-sectional study included 81 mothers of children with ADHD and 80 mothers of typically developing peers. FM was evaluated according to the American College of Rheumatology 2016 criteria. Psychometric evaluations included the Fibromyalgia Impact Questionnaire (FIQ), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Autism-Spectrum Quotient (AQ), along with a structured sociodemographic form. Group comparisons and multivariable logistic regression analyses were conducted to identify independent predictors of FM.</div></div><div><h3>Results</h3><div>FM prevalence was significantly higher in mothers of children with ADHD compared with controls (38.3% vs. 7.5%, <em>p</em> &lt; 0.001). Mothers in the ADHD group also reported markedly elevated anxiety and depressive symptoms. In univariate analyses, higher maternal anxiety, depressive symptoms, autistic traits, and a history of psychiatric disorder were associated with FM. In the fully adjusted model, however, only higher maternal anxiety and older child age remained independent predictors of FM in the ADHD group. When the full sample was analyzed, having a child with ADHD was also independently associated with maternal FM. FM severity demonstrated moderate positive correlations with anxiety and depression.</div></div><div><h3>Conclusion</h3><div>Mothers of children with ADHD constitute a high-risk group for FM, likely driven by chronic caregiving stress and associated psychological burden. Routine screening and early psychosocial support interventions targeting parental mental health may help prevent or mitigate FM-related disability in this vulnerable population.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112561"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146120716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between physical activity, body esteem, and self-esteem among women with breast and gynecological cancer","authors":"Anna Weronika Szablewska ,&nbsp;Bartosz Zając ,&nbsp;Martyna Lesińska ,&nbsp;Rita Santos - Rocha ,&nbsp;Anna Szumilewicz","doi":"10.1016/j.jpsychores.2026.112547","DOIUrl":"10.1016/j.jpsychores.2026.112547","url":null,"abstract":"<div><h3>Background</h3><div>Gynecological and breast cancers are among the most prevalent malignancies in women. While survival has improved due to advances in treatment, many survivors experience challenges such as body image disturbances and reduced self-esteem. Physical activity has been identified as a potential protective factor, but evidence specific to this population remains limited.</div></div><div><h3>Aim</h3><div>The aim of this study was to evaluate the differences in body image and self-esteem among physically active and inactive women with a history of gynecological and breast cancer, as compared to active and inactive healthy controls.</div></div><div><h3>Methods</h3><div>A cross-sectional online survey was conducted in Poland. Participants were allocated to four groups according to cancer status and physical activity: inactive controls (CON-PI), active controls (CON-PA), inactive cancer survivors (CAN-PI), and active cancer survivors (CAN-PA). Physical activity was defined based on World Health Organization recommendations. Body image and self-esteem were assessed using the Body-Esteem Scale for Adolescents and Adults (BESAA) and the Rosenberg Self-Esteem Scale (RSES).</div></div><div><h3>Results</h3><div>Physically active women reported significantly higher BESAA and RSES scores compared to inactive women. The CAN-PI group consistently showed the lowest scores across all domains, while the CON-PA group reported the highest. Differences were particularly marked in appearance, attribution, and global self-esteem.</div></div><div><h3>Conclusions</h3><div>Meeting WHO-recommended physical activity levels was associated with more positive body image and higher self-esteem in women after gynecological and breast cancer treatment. The findings highlight the potential role of physical activity in psychosocial well-being and support its inclusion in survivorship care.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112547"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146025754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unravelling the role of brain-derived neurotrophic factor (BDNF) in anorexia, bulimia, and binge-eating disorder: A systematic review and meta-analysis","authors":"Massimo Fioranelli ,&nbsp;Pietro Sedati ,&nbsp;Alessia Topa ,&nbsp;Maria Grazia Roccia ,&nbsp;Giancarlo Santoni ,&nbsp;Maria Luisa Garo","doi":"10.1016/j.jpsychores.2026.112580","DOIUrl":"10.1016/j.jpsychores.2026.112580","url":null,"abstract":"<div><h3>Background</h3><div>Brain-derived neurotrophic factor (BDNF) plays a role in neuroplasticity, appetite regulation, and reward processing. Its possible involvement in eating disorders (EDs) has been investigated; however, contradictory findings and substantial methodological heterogeneity have prevented definitive conclusions.</div></div><div><h3>Objective</h3><div>To systematically evaluate peripheral BDNF levels in individuals with EDs, healthy controls and recovered individuals.</div></div><div><h3>Methods</h3><div>A systematic review with meta-analysis was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement (CRD420250654199). Observational studies and randomized controlled trials comparing BDNF levels in individuals with and without EDs were included. The Newcastle-Ottawa Scale and risk-of-bias tool for randomized trials were used.</div></div><div><h3>Results</h3><div>Twenty-one studies were included. BDNF serum levels were significantly lower in acute anorexia (AN) compared with healthy controls (Standardized Mean Difference [SMD] = −0.49;<em>p</em> &lt; 0.001,<em>n</em> = 17), with significance maintained after excluding outliers (SMD = –0.41; p &lt; 0.001,<em>n</em> = 8). No significant difference was found between recovered AN and controls. Bulimia nervosa (BN) individuals showed significantly lower BDNF serum levels (SMD = –0.72;<em>p</em> &lt; 0.001,<em>n</em> = 4). Longitudinal studies showed a significant increase in serum BDNF levels after recovery (SMD = 1.78;<em>p</em> = 0.003,<em>n</em> = 6).</div></div><div><h3>Discussion</h3><div>These findings support a predominantly state-related association between peripheral BDNF levels and illness stage in AN and BN, rather than a stable condition-specific. Evidence for binge-eating disorders is extremely limited, relying on a single eligible study. Interpretation is constrained by methodological heterogeneity, variability in recovery definitions, and the largely correlational nature of the evidence. Further standardized, high-quality longitudinal studies are needed to clarify whether peripheral BDNF alterations reflect state-related mechanisms, trait vulnerability, or dynamic biological changes across illness stages.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112580"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146174333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Illness perception profiles and psychological and subjective physical symptoms in atrial fibrillation","authors":"Minjie Zheng,&nbsp;Xinxin Shi,&nbsp;Zhijuan Xie,&nbsp;Shiyu Zhang,&nbsp;Shan Qu","doi":"10.1016/j.jpsychores.2026.112540","DOIUrl":"10.1016/j.jpsychores.2026.112540","url":null,"abstract":"<div><h3>Background</h3><div>Illness perceptions have been associated with outcomes in patients with atrial fibrillation (AF). This study aimed to identify distinct illness perception profiles in patients with AF and examine their associations with psychological and physical responses.</div></div><div><h3>Method</h3><div>A total of 150 patients with AF were enrolled in this study. Illness perception profiles were identified using latent profile analysis (LPA). Model fit indices were evaluated to determine the optimal class solution. Logistic regression analyses were conducted to examine the associations between illness perception profiles and psychological and physical outcomes, including Generalized anxiety disorder-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9), 12-Item Short Form Health Survey (SF-12) and University of Toronto atrial fibrillation severity scale (AFSS).</div></div><div><h3>Result</h3><div>A two-class model was identified as optimal, comprising a “Reactive–Minimizing” profile (Class 1, 49%) and a “Symptom-Helplessness” profile (Class 2, 51%). Univariate logistic analysis revealed significant differences between classes in age, AF type, work status, PHQ-9, AFSS-symptoms, and AFSS-burden. In the multivariable logistic regression adjusted for age and sex (logistic outcome: Class 2 vs. Class 1), higher AFSS-burden scores were independently associated with the “Symptom-Helplessness” profile (OR = 1.26, 95% CI: 1.09–1.45, <em>p</em> = 0.001). Conversely, higher PHQ-9 scores were associated with the “Reactive–Minimizing” profile (OR for Symptom-Helplessness = 0.92, 95% CI: 0.86–0.99, <em>p</em> = 0.018).</div></div><div><h3>Conclusion</h3><div>Person-centered illness perception profiling revealed two distinct cognitive–emotional patterns in patients with AF that were associated with depressive symptoms and symptom burden, highlighting their potential value for individualized psychological and clinical management.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112540"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative anxiety is associated with postoperative cardiovascular events, extubation delay, and pain in patients undergoing cardiac surgery: A prospective observational study in Taiwan","authors":"Siao-Ya Su ,&nbsp;Jiin-Ling Jiang ,&nbsp;Jui-Chih Chang ,&nbsp;Jen-Hung Wang ,&nbsp;Malcolm Koo","doi":"10.1016/j.jpsychores.2026.112576","DOIUrl":"10.1016/j.jpsychores.2026.112576","url":null,"abstract":"<div><h3>Objective</h3><div>Preoperative anxiety is common among patients undergoing cardiac surgery and may influence early postoperative recovery. Evidence linking anxiety to clinically relevant postoperative outcomes remains limited, particularly in non-Western populations. This study examined the association between preoperative anxiety and multiple postoperative outcomes in patients undergoing cardiac surgery in Taiwan.</div></div><div><h3>Methods</h3><div>In this prospective observational study, 113 adult patients scheduled for elective cardiac surgery were enrolled at a tertiary medical center in Eastern Taiwan. Preoperative anxiety was assessed using the Visual Analogue Scale for Anxiety (VAS-A; 0–10 scale). Outcomes included cardiovascular adverse events and non-arrhythmia-related cardiovascular events within 30 days postoperatively, delayed extubation (≥6 h), and mean 7-day postoperative pain, defined as a Critical-Care Pain Observation Tool score ≥ 2. Associations were evaluated using multivariable Firth's penalized logistic regression. Absolute risk estimates were derived at representative low and high anxiety levels.</div></div><div><h3>Results</h3><div>Higher preoperative VAS-A scores were independently associated with increased odds of cardiovascular adverse events (adjusted odds ratio [aOR], 1.34), non-arrhythmia-related cardiovascular events (aOR, 1.40), and delayed extubation (aOR, 1.40). The association with mean 7-day postoperative pain approached but did not reach conventional statistical significance after adjustment (aOR, 1.18). Absolute risk estimates demonstrated substantial differences across anxiety levels for all outcomes.</div></div><div><h3>Conclusion</h3><div>Preoperative anxiety is independently associated with several adverse postoperative outcomes after cardiac surgery. These findings support the potential value of brief preoperative anxiety screening as a pragmatic tool for perioperative risk identification. Further studies are needed to determine whether targeted anxiety management can improve postoperative clinical outcomes.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112576"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association among social participation, loneliness and depression in stroke survivors: A longitudinal cross-lagged panel analysis","authors":"Liping Sun ,&nbsp;Yuexia Liao ,&nbsp;Zhi'e Gu ,&nbsp;Xiaojuan Wan ,&nbsp;Ningning Liu","doi":"10.1016/j.jpsychores.2026.112553","DOIUrl":"10.1016/j.jpsychores.2026.112553","url":null,"abstract":"<div><h3>Objective</h3><div>To examine longitudinal associations among depressive symptoms, loneliness, and social participation in stroke survivors, and the temporal role of loneliness between social participation and depressive symptoms.</div></div><div><h3>Methods</h3><div>277 stroke survivors were conveniently sampled from two tertiary hospitals in Yangzhou, China. Depressive symptoms, loneliness, and social participation were assessed using the Patient Health Questionnaire-9, UCLA Loneliness Scale, and Utrecht Scale for Evaluation of Rehabilitation-Participation, respectively. Data were collected at baseline (T1), 3 months (T2), and 6 months (T3) post-stroke, with a cross-lagged panel model used to examine the reciprocal relationships among variables.</div></div><div><h3>Results</h3><div>Cross-lagged panel analysis revealed: T1 depressive symptoms positively predicted T2 loneliness (<em>β</em> = 0.133, <em>P</em> = 0.046)；T1 social participation negatively predicted T2 loneliness (<em>β</em> = −0.226, <em>P</em> &lt; 0.001) and depressive symptoms (<em>β</em> = −0.256, <em>P</em> &lt; 0.001)；T2 depressive symptoms negatively predicted T3 social participation (<em>β</em> = −0.098, <em>P</em> = 0.027)；T2 loneliness positively predicted T3 depressive symptoms (<em>β</em> = 0.171, <em>P</em> = 0.006)；T2 social participation negatively predicted T3 loneliness (<em>β</em> = −0.174, <em>P</em> = 0.001). Mediation analysis showed T2 loneliness mediated T1 social participation's effect on T3 depressive symptoms (indirect effect = −0.037, 95% <em>CI</em> [−0.082, −0.010]).</div></div><div><h3>Conclusion</h3><div>Alternating cross-lagged effects were observed among depressive symptoms, loneliness, and social participation in stroke survivors, with loneliness potentially acting as a mediator between social participation and subsequent depressive symptoms. These findings suggest hypotheses for phase-specific interventions, which should be tested in future studies.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112553"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146015598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distress in postural orthostatic tachycardia syndrome (POTS) is largely driven by ineffective healthcare, not patients' attitudes","authors":"Svetlana Blitshteyn ,&nbsp;Blair P. Grubb","doi":"10.1016/j.jpsychores.2026.112552","DOIUrl":"10.1016/j.jpsychores.2026.112552","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112552"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146025727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Loneliness and somatic complaints: An experience sampling method study","authors":"Martine Smeets ,&nbsp;Elody Hutten ,&nbsp;Peter Verboon ,&nbsp;Yvonne Bol ,&nbsp;Viviane Thewissen ,&nbsp;Ellen M.M. Jongen","doi":"10.1016/j.jpsychores.2026.112554","DOIUrl":"10.1016/j.jpsychores.2026.112554","url":null,"abstract":"<div><h3>Objective</h3><div>Previous studies have shown a positive relation between retrospectively measured loneliness and somatic complaints. This study investigated the relation between state loneliness and state somatic complaints as well as the direction of this relation in the context of daily life. It was hypothesized that there is a positive contemporaneous association between state loneliness and state somatic complaints as well as a positive bidirectional temporal association.</div></div><div><h3>Methods</h3><div>Using the Experience Sampling Method, 16 patients with somatic symptom disorder and 27 participants from the general population received a signal on their smartphones 10 times a day for 14 days to fill out an ESM-item on loneliness and two on somatic complaints. To test our hypotheses, multilevel linear regression models with random effects were estimated.</div></div><div><h3>Results</h3><div>Associations between state loneliness and state somatic complaints in the context of daily life were demonstrated (B = 0.12, SE = 0.01, <em>p</em> &lt; .001). Temporal analyses revealed, however, that state loneliness (t-1) did not predict somatic complaints (t) in daily life (90-min window; B = 0.01, SE = 0.01, <em>p</em> = .573). Neither did state somatic complaints predict state loneliness (B = 0.02, SE = 0.03, <em>p</em> = .534).</div></div><div><h3>Conclusions</h3><div>This study demonstrated contemporaneous associations between state loneliness and state somatic complaints in the context of daily life. However, state loneliness did not predict subsequent state somatic complaints, nor did state somatic complaints predict subsequent state loneliness. Future studies are necessary to further disentangle the complex relationship between loneliness and somatic complaints.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112554"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146025755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stigma in functional neurological disorder; a longitudinal study","authors":"Caoimhe Mcloughlin ,&nbsp;Neil Ramsay ,&nbsp;Lineke Tak ,&nbsp;Alan Carson ,&nbsp;Jon Stone","doi":"10.1016/j.jpsychores.2026.112550","DOIUrl":"10.1016/j.jpsychores.2026.112550","url":null,"abstract":"<div><h3>Background</h3><div>Stigma in Functional Neurological Disorder has been consistently reported by patient organisations as one of their biggest challenges. We aimed to longitudinally evaluate different components of stigma, namely perceived, internalised (self) and anticipated stigma experienced by patients with FND, and to explore associated factors.</div></div><div><h3>Methods</h3><div>Participants were mainly recruited prospectively via outpatient clinics at two centres, shortly after communicating the diagnosis. Measures included: perceived, internalised and anticipated stigma, somatic symptom burden, quality of life, depression, anxiety, illness attribution, and experience of care.</div></div><div><h3>Results</h3><div>Ninety-six respondents completed the baseline survey, of which 80 completed the follow-up (mean duration 7 months). Perceived stigma (Stigma Scale for Chronic Illness-8, mean 21.2) scores were in the moderate range. Regarding internalised stigma, 32% agreed they had considered that FND was their fault. Anticipated stigma was experienced most from work, followed by healthcare, then friends and family. Participants held a balanced view of their condition as physical and psychological in contrast to their perception of <em>others'</em> understanding of FND as psychological – which in turn significantly related to higher stigma scores. Identifying as a man, being in a relationship, higher age and level of education were statistically significantly protective against stigma. At follow up, perceived, self, and anticipated stigma, somatic symptom burden, quality of life, anxiety and depression scores did not change significantly.</div></div><div><h3>Conclusion</h3><div>People with FND experience high levels of perceived, self and anticipated stigma, and have high rates of physical and psychological comorbidity, which, in this cohort, did not improve over time. Counter-stigma approaches need to consider these different sources of stigma, outside just healthcare professionals.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"203 ","pages":"Article 112550"},"PeriodicalIF":3.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146025728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}