Journal of Psychosomatic Research最新文献

{"title":"“Circadian rhythms and health: Chronobiological strategies for enhancing physical and mental well-being”","authors":"Ulfah ,&nbsp;Kadek Suhardita ,&nbsp;Rikas Saputra ,&nbsp;Erfan Ramadhani ,&nbsp;Palasara Brahmani Laras ,&nbsp;Rr Dwi Umi Badriyah","doi":"10.1016/j.jpsychores.2025.112149","DOIUrl":"10.1016/j.jpsychores.2025.112149","url":null,"abstract":"<div><div>Circadian rhythms play a vital role in regulating physiological and psychological functions, yet modern lifestyles increasingly disrupt these biological cycles, contributing to a rise in sleep disorders, metabolic dysfunctions, and mental health challenges. This article explores the significance of circadian regulation and presents chronobiological strategies to optimize physical and mental well-being. Key interventions include light exposure management, meal timing adjustments, and sleep hygiene improvements. Despite advancements, challenges remain in integrating these insights into public health policies and daily routines. Emerging solutions, such as precision chronotherapy and AI-driven circadian health monitoring, offer personalized approaches to mitigating circadian misalignment. By adopting these strategies, societies can enhance productivity, cognitive function, and overall health, fostering long-term disease prevention.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"194 ","pages":"Article 112149"},"PeriodicalIF":3.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between lung function and cognitive impairment among middle-aged and older adults: The mediating role of depressive symptoms","authors":"Yubin Wang,&nbsp;Jifeng Huang,&nbsp;Yuhan Tao,&nbsp;Yuling Zhang,&nbsp;Xiaojie Zhou,&nbsp;Hui Mao","doi":"10.1016/j.jpsychores.2025.112148","DOIUrl":"10.1016/j.jpsychores.2025.112148","url":null,"abstract":"<div><h3>Background</h3><div>To date, the mechanisms underlying the relationship between lung function and cognitive decline remain poorly understood. This study aims to investigate the mediating effect of depression in the longitudinal association between lung function and subsequent cognitive impairment (CI).</div></div><div><h3>Methods</h3><div>In the China Health and Retirement Longitudinal Study (CHARLS), a total of 7275 participants were included in the final analysis. Lung function was evaluated using peak expiratory flow (PEF) measured by a peak flow meter. A composite cognitive score was used to assess cognitive function. Linear and logistic regression models, along with bootstrap analyses, were used to investigate the mediating effect of depressive symptoms on the relationship between lung function and cognitive decline.</div></div><div><h3>Results</h3><div>After adjusting for potential covariates, scores on both overall cognition and its four dimensions demonstrated an increasing trend from quartile 1 (Q1) to quartile 4 (Q4) of PEF and PEF% predicted (<em>p</em> &lt; 0.001). Higher PEF values (Q4 vs Q1: OR = 0.93, 95 % CI 0.90 to 0.97, <em>p</em> = 0.001) as well as elevated PEF% predicted (Q4 vs Q1: OR = 0.94, 95 % CI 0.90 to 0.97, <em>p</em> = 0.001) were associated with a reduced risk of developing CI onset. The mediation effect of depression accounted for approximately 8.2 % of the total effect concerning lung function's impact on cognitive decline.</div></div><div><h3>Conclusion</h3><div>Higher PEF was associated with a slower rate of longitudinal cognitive decline in middle-aged and older adults. Although depressive symptoms acted as a mediator associated with the development of CI, the majority of variance remained unexplained.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"193 ","pages":"Article 112148"},"PeriodicalIF":3.5,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144069688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding horizons in chronic pain research: From psychological factors to global relevance","authors":"Rusnila ,&nbsp;Riza Amalia ,&nbsp;Lutfatulatifah ,&nbsp;Tamama Rofiqoh ,&nbsp;Hanik Mufaridah","doi":"10.1016/j.jpsychores.2025.112145","DOIUrl":"10.1016/j.jpsychores.2025.112145","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"194 ","pages":"Article 112145"},"PeriodicalIF":3.5,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144098430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multidimensional outcomes associated with chronic fatigue over 12 months in youth with emerging mood disorders","authors":"Emiliana Tonini ,&nbsp;Jacob J. Crouse ,&nbsp;Mirim Shin ,&nbsp;Joanne S. Carpenter ,&nbsp;Andrew R. Lloyd ,&nbsp;Gabrielle Hindmarsh ,&nbsp;Sarah McKenna ,&nbsp;Alissa Nichles ,&nbsp;Natalia Zmicerevska ,&nbsp;Jan Scott ,&nbsp;Frank Iorfino ,&nbsp;Christos Pantelis ,&nbsp;Barnaby Nelson ,&nbsp;Patrick D. McGorry ,&nbsp;Stephen J. Wood ,&nbsp;Alison R. Yung ,&nbsp;Rosemary Purcell ,&nbsp;Ian B. Hickie","doi":"10.1016/j.jpsychores.2025.112141","DOIUrl":"10.1016/j.jpsychores.2025.112141","url":null,"abstract":"<div><h3>Background</h3><div>Complaints of chronic fatigue lasting weeks or longer are common during adolescence. Little is known about factors associated with chronic fatigue in youth with mood disorders or potential sex-specific associations.</div></div><div><h3>Methods</h3><div>496 young people (mean age = 18.36-years, SD = 3.22; 69 % female) seeking help for mental healthcare were assessed on psychological symptoms, lifestyle, and sleep at baseline and 12-months later. Fatigue was defined as a score of ≥3 on the somatic subscale of the Somatic and Psychological Health Report. Logistic regression models were used to examine associations between clinical, lifestyle, and related factors and chronic fatigue caseness, including main effects and sex interactions.</div></div><div><h3>Results</h3><div>Half (52 % [<em>N</em> = 260]) of the sample reported fatigue at both baseline and 12-month follow-up (“<em>chronic fatigu</em>e”). Univariately, chronic fatigue cases were more commonly at later clinical stages of mental disorder and had worse mental health, sleep disturbance, and disability at baseline and follow-up. In covariate-adjusted analyses, being a chronic fatigue case was associated with persistently elevated anxiety and, at 12-month follow-up, more disability, weight gain, and shorter sleep duration. In sex-interaction analyses, chronic fatigue in females was associated with longer sleep latency at follow-up (OR = 1.97), but not in males.</div></div><div><h3>Conclusion</h3><div>Chronic fatigue was common and associated with poorer mental health and functioning longitudinally. While there were no sex differences in the rates of chronic fatigue, there were some sex differences in the factors associated with it. Systematic screening and early intervention for chronic fatigue, considering sex-specific factors, may improve multidimensional outcomes in youth with emerging mood disorders.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"193 ","pages":"Article 112141"},"PeriodicalIF":3.5,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143928876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sociodemographic and psychosocial correlates of fatigue and chronic fatigue: A cross-sectional study from a South East London community survey","authors":"Shuo Zhang ,&nbsp;Stephani L. Hatch ,&nbsp;Matthew Hotopf ,&nbsp;Graham Thornicroft ,&nbsp;Trudie Chalder ,&nbsp;Jayati Das-Munshi","doi":"10.1016/j.jpsychores.2025.112146","DOIUrl":"10.1016/j.jpsychores.2025.112146","url":null,"abstract":"<div><h3>Objective</h3><div>A better understanding of fatigue and chronic fatigue symptoms in the community may lead to better targeted preventative interventions. This study aims to estimate the prevalence of fatigue and chronic fatigue and explore relationships with sociodemographic and psychosocial factors in a representative community population survey in London, UK.</div></div><div><h3>Methods</h3><div>The first wave of the South East London Community Health study (2008 to 2010) surveyed face-to-face 1698 individuals aged 16 years and over from 1075 randomly selected households in the boroughs of Southwark and Lambeth. Self-reported fatigue and/or chronic fatigue was determined using the Chalder fatigue scale. Ordinal and binary logistic regression analyses were undertaken to assess the association of sociodemographic and psychosocial factors with higher levels of fatigue symptoms.</div></div><div><h3>Results</h3><div>The point prevalence of fatigue was 23.5 % (95 % CI 21.5–25.7). After adjusting for age and sex, higher levels of fatigue were substantially associated with impacts on work and other activities due to physical (OR: 4.87 (95 % CI 3.44–6.88)) or emotional symptoms (OR: 4.52 (95 % CI, 3.16–6.48)). Higher levels of fatigue were also associated with seeking emotional help from professionals (OR: 2.73 (95 % CI, 1.91–3.92) or family or friends (OR: 2.37 (95 % CI,1.68–3.34) and reporting less perceived instrumental (OR: 2.01 (0.75–5.37)) and emotional support (OR: 3.76 (1.46–9.68)).</div></div><div><h3>Conclusion</h3><div>Our findings highlight the high prevalence of fatigue and chronic fatigue in a representative urban community sample. Higher levels of fatigue were significantly associated with greater disability and formal and informal help-seeking. The quality of perceived social support is an important protective factor.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"193 ","pages":"Article 112146"},"PeriodicalIF":3.5,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘A name to the pain’: A mixed methods analysis of diagnostic delay and perceptions of diagnosis importance in Australians with endometriosis","authors":"Danielle Mosterd ,&nbsp;Subhadra Evans ,&nbsp;Leesa Van Niekerk ,&nbsp;David Skvarc ,&nbsp;Mathew Leonardi ,&nbsp;Katherine Stanley ,&nbsp;Antonina Mikocka-Walus","doi":"10.1016/j.jpsychores.2025.112143","DOIUrl":"10.1016/j.jpsychores.2025.112143","url":null,"abstract":"<div><div>Diagnostic delay is a significant issue facing people with endometriosis; however, the Australian perspective and participant voice is missing for why delay occurs. The current study aimed to assess the length of diagnostic delay, whether this is changing over time, correlates of longer delay and the importance of diagnosis. This study utilised a mixed methods cross-sectional online survey of people with endometriosis (<em>n</em> = 506). Individuals with self-reported endometriosis were recruited via social media and websites of Australian endometriosis organisations completing an online, cross-sectional survey. Hierarchical multiple regression, ANOVA and template analysis were conducted. Participants reported an average diagnostic delay of 12.3 years (<em>SD</em> = 7.7), with delay appearing shorter in those who first saw a general practitioner (GP) for their symptoms since 2018 (mean 4.7 years, <em>SD</em> = 3.4). More recent endometriosis-related symptom onset, younger age at diagnosis, and accessing medical care through public healthcare were associated with shorter delays, whilst seeing a higher number of doctors prior to diagnosis and queer identity was associated with longer delays. Participants indicated that diagnostic delay most commonly occurs due to dismissal and disbelief by medical professionals and qualitative accounts revealed that receiving a diagnosis is important for many reasons. Diagnostic delay is perceived as a barrier to receiving timely, effective care for endometriosis. Increased societal and medical professional knowledge regarding symptoms indicative of endometriosis, and early treatment and clinical skills focused on pain validation and acknowledgement are recommended to improve timely diagnosis.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"193 ","pages":"Article 112143"},"PeriodicalIF":3.5,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143928877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dyadic effects of eHealth literacy on health-promoting behaviors in older adults with stroke and their family caregivers: The mediating role of self-efficacy","authors":"Chen Xu ,&nbsp;Lei Qian ,&nbsp;Yanhui Qiu ,&nbsp;Fen Ye ,&nbsp;Jianru Hao ,&nbsp;Jun Wang ,&nbsp;Yuyu Qiu","doi":"10.1016/j.jpsychores.2025.112144","DOIUrl":"10.1016/j.jpsychores.2025.112144","url":null,"abstract":"<div><h3>Aim</h3><div>Health-promoting behaviors (HPB) are crucial for older adults with stroke and their family caregivers. This study aimed to explore the dyadic effects of eHealth literacy (eHL) on HPB among older adults with stroke and their family caregivers, as well as whether self-efficacy (SE) mediated this relationship.</div></div><div><h3>Methods</h3><div>A cross-sectional approach was used to collect data from 293 survivor-caregiver dyads. Questionnaires measuring eHL, SE, and HPB were completed by participants. Data analysis was conducted using the actor-partner interdependence mediation model.</div></div><div><h3>Results</h3><div>In terms of actor effects, eHL of both survivors and caregivers was positively associated with their HPB through their respective SE (survivor: <em>β</em> = 0.142, <em>P</em> &lt; 0.001; caregiver: <em>β</em> = 0.167, <em>P</em> &lt; 0.001). Regarding partner effects, caregivers' eHL was positively associated with survivors' HPB, with this relationship mediated by survivors' SE (<em>β</em> = 0.112, <em>P</em> &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>There were intrapersonal and interpersonal associations among eHL, SE, and HPB in older adults with stroke and their family caregivers. It suggested that eHL was positively related to HPB in dyads and revealed the potential mediating role of SE. It provides valuable guidance for dyadic interventions to enhance HPB and improve the overall well-being of older adults with stroke and their family caregivers.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"193 ","pages":"Article 112144"},"PeriodicalIF":3.5,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143929375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effective interventions to reduce sick leave in workers with mental illnesses: A systematic review of randomized controlled trials","authors":"Rahman Shiri,&nbsp;Pekka Varje,&nbsp;Salla Toppinen-Tanner","doi":"10.1016/j.jpsychores.2025.112140","DOIUrl":"10.1016/j.jpsychores.2025.112140","url":null,"abstract":"<div><h3>Objective</h3><div>Effective interventions to reduce sick leave in people with mental illnesses remain unknown. This systematic review of randomized controlled trials (RCTs) assessed the impact of various interventions on reducing sick leave among individuals with mental illnesses.</div></div><div><h3>Methods</h3><div>We conducted searches in PubMed, Cochrane Library, and PsycInfo until February 2024 and included RCTs with parallel designs. Two reviewers assessed the quality of trials using the Cochrane risk of bias tool (ROB-2).</div></div><div><h3>Results</h3><div>Out of 5109 publications, 75 RCTs were included. Ten RCTs with no serious risk of bias demonstrated that certain interventions could reduce sick leave. Interventions based on cognitive behavioral therapy and problem-solving therapy reduced sick leave within a year, but the effect was not long-lasting. Enhanced care approaches, where physicians and care managers encouraged patients to start and maintain pharmacotherapy or psychotherapy, also decreased absenteeism. Online cognitive behavioral therapy yielded a modest decrease in absenteeism. An intervention involving both employees and supervisors to modify the workplace and address stress reduced long-term sick leave. Involving employees in stressor management initiatives decreased sick leave, and a combination of work-focused and online cognitive behavioral therapy reduced short-term sick leave but did not affect long-term (≥15 days) rates. Group therapy led by a clinical psychologist for stress management also showed benefits in the short term (3 months).</div></div><div><h3>Conclusion</h3><div>Multifaceted approaches that combine individual therapy and workplace adjustments are more effective in managing sick leave for individuals with mental illnesses than either approach alone.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"193 ","pages":"Article 112140"},"PeriodicalIF":3.5,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143918398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined influence of healthy lifestyles, nutritional and inflammatory status on mortality among US adults with depression","authors":"Jumei Yin ,&nbsp;Lan Jiang ,&nbsp;Huan Zhang ,&nbsp;Jinming Zhang ,&nbsp;Ju Zhang ,&nbsp;Nuo Yao ,&nbsp;Yongquan Shi ,&nbsp;Zheyi Han","doi":"10.1016/j.jpsychores.2025.112131","DOIUrl":"10.1016/j.jpsychores.2025.112131","url":null,"abstract":"<div><h3>Objective</h3><div>Healthy lifestyles, nutritional and inflammatory status are interrelated and influence mortality. This study aimed to evaluate their separate and combined effects on all-cause and cause-specific mortality in individuals exhibiting depression.</div></div><div><h3>Methods</h3><div>6143 individuals with depression (median age 47) were recruited from the US National Health and Nutrition Examination Survey (NHANES 2005–2018), with mortality followed up through December 31, 2019. A healthy lifestyle score (0–5) was constructed based on current non-smoking, low-to-moderate alcohol consumption, adequate sleep, sufficient physical activity and healthy diet. Higher scores indicated healthier lifestyles. The Advanced Lung Cancer Inflammation Index (ALI), a composite marker of inflammation and nutritional status, was calculated as Body Mass Index (BMI) (kg/m²) × albumin (g/dl)/Neutrophil-to-Lymphocyte Ratio (NLR). Higher ALI values denoted lower inflammation and better nutrition. Weighted Cox proportional-hazards models were used to estimate mortality hazard ratios.</div></div><div><h3>Results</h3><div>Healthier lifestyles significantly lowered all-cause (hazard ratio [HR] 0.72, 95 % confidence interval [CI] 0.66–0.78), cardiovascular (HR 0.70, 95 % CI 0.58–0.83), and non-cardiovascular mortality (HR 0.72, 95 % CI 0.64–0.81). High ALI reduced all-cause (HR 0.70, 95 % CI 0.54–0.91) and cardiovascular mortality (HR 0.46, 95 % CI 0.28–0.77) compared with low ALI. Joint analyses showed that individuals with both healthy lifestyle scores ≥3 and high ALI had the lowest risk of all-cause, cardiovascular, and non-cardiovascular mortality (HR 0.44, 95 % CI 0.33–0.60; 0.32, 95 % CI 0.16–0.63; 0.49, 95 % CI 0.35–0.68).</div></div><div><h3>Conclusion</h3><div>The joint presence of healthy lifestyles and high ALI was significantly associated with lower risk of mortality among individuals with depression.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"193 ","pages":"Article 112131"},"PeriodicalIF":3.5,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143869433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of obsessive beliefs on fibromyalgia: The mediating role of emotional dysfunction and obsessive-compulsive symptoms","authors":"Burak Okumus ,&nbsp;Makbule Esen Oksuzoglu ,&nbsp;Nihal Yılmaz ,&nbsp;Hande Gunal Okumus","doi":"10.1016/j.jpsychores.2025.112128","DOIUrl":"10.1016/j.jpsychores.2025.112128","url":null,"abstract":"<div><h3>Background</h3><div>The role of obsessive beliefs in the development and maintenance of Fibromyalgia syndrome (FMS) remains unclear. This study aims to compare patients with FMS and controls in terms of obsessive beliefs, quality of life, and comorbid psychiatric symptoms. In addition, this study uses structural equation modelling (SEM) to examine whether obsessive beliefs influence FMS symptom severity directly or through mediating factors.</div></div><div><h3>Method</h3><div>This study was conducted at Uşak Training and Research Hospital, Turkey, involving 116 adults, including 76 FMS patients (mean age = 43.2) and 40 controls (mean age = 45.8). Both groups completed the Short Form 12 Health Survey (SF-12), Obsessive Beliefs Questionnaire (OBQ) and Symptom Checklist-90 Revised (SCL-90-R), with the FMS group additionally completing the Fibromyalgia Impact Questionnaire (FIQ). SEM was applied to examine the direct and indirect effects of obsessive beliefs on FMS symptom severity.</div></div><div><h3>Results</h3><div>In the FMS group, SF-12 subscale scores were lower, while OBQ-44 and SCL-90-R subscale scores (except for anger-hostility, phobic anxiety, and paranoid ideation) were higher compared to controls (all <em>p &lt; .05).</em> The final model showed that the OBQ-Total Score negatively predicted SF-12 Role Emotional (β = −0.22, <em>p</em> = .042) and positively predicted SCL-90 Obsessive-Compulsive (β = 0.25, <em>p</em> = .013). SF-12 Role Emotional negatively predicted both the FIQ (β = −0.50, <em>p</em> &lt; .001) and SCL-90 Obsessive-Compulsive (β = −0.40, <em>p</em> = .001), while SCL-90 Obsessive-Compulsive positively predicted the FIQ (β = 0.39, <em>p</em> = .002).</div></div><div><h3>Conclusions</h3><div>Our findings highlight the role of obsessive beliefs and emotional dysfunction in FMS severity, suggesting that targeting these factors may help alleviate symptoms. Future research should examine targeted therapies to enhance emotional regulation and cognitive flexibility in FMS.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112128"},"PeriodicalIF":3.5,"publicationDate":"2025-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143825763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}