Rachel E. Menzies , Tadgh Connery , Daniel Macdonald , Grazia D. Riotto
{"title":"The relationship between death anxiety and fear of recurrence and progression in chronic illness: A systematic review and meta-analysis","authors":"Rachel E. Menzies , Tadgh Connery , Daniel Macdonald , Grazia D. Riotto","doi":"10.1016/j.jpsychores.2025.112373","DOIUrl":"10.1016/j.jpsychores.2025.112373","url":null,"abstract":"<div><h3>Objective</h3><div>Recent research has identified fear of recurrence and fear of progression (FORP) as common psychosocial issues among people with chronic illnesses. Similarly, growing studies have identified death anxiety as being a key transdiagnostic construct in mental health, particularly in relation to anxiety. However, the relationship between these constructs has received scarce attention. This systematic review and meta-analysis examined the relationship between FORP and death anxiety across chronic illnesses.</div></div><div><h3>Methods</h3><div>The current review was conducted in line with PRISMA guidelines. We screened 2620 papers for the current systematic review and meta-analysis. In total, 15 studies were included in the final review (<em>N</em><sub>total</sub> <em>=</em> 3506).</div></div><div><h3>Results</h3><div>A meta-analysis revealed a significant and large correlation (<em>r</em> = 0.592) between death anxiety and overall FORP. The type of illness emerged as a significant moderator of this effect, with significantly larger effect sizes found for samples affected by cancer (<em>r</em> = 0.640) compared with other illnesses (<em>r</em> = 0.495). The relationship with death anxiety was equally strong between studies which measured fear of progression versus fear of recurrence. Overall, the studies were generally of high quality with low risk of publication bias.</div></div><div><h3>Conclusions</h3><div>The current findings support the significant relationship between death anxiety and FORP across numerous illness types. The clinical implications include the need to consider death anxiety in the conceptualisation and management of FORP in chronic illness.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"198 ","pages":"Article 112373"},"PeriodicalIF":3.3,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feasibility of using a clinical measure of depression severity to assess treatment impact on total cost of care","authors":"Daniel Maeng, Hochang B. Lee, George S. Nasra","doi":"10.1016/j.jpsychores.2025.112375","DOIUrl":"10.1016/j.jpsychores.2025.112375","url":null,"abstract":"<div><h3>Objective</h3><div>Patient Health Questionnaire 9-item (PHQ9) has become a commonly used clinical measure of depression severity. This study therefore seeks to determine whether reductions in PHQ9 scores (i.e., symptom severity improvement) correspond to cost of care savings from the payer's perspective.</div></div><div><h3>Methods</h3><div>The study team obtained health insurance claims data and the PHQ9 scores of same individuals among employees of a large academic employer in the United States covering a two-year period from October 2016 to September 2018, limiting the sample to those who had at least two PHQ9 scores in two separate calendar months during a 12-month period, had initial score of 10 or above, and maintained continuous insurance enrollment for the 12-month period. The study team divided the sample into 3 mutually exclusive groups: no improvement within the 12-month period (NI; PHQ9 score remained unchanged or worsened), partial improvement (PI; 1 %–49 % improvement), or clinically significant improvement (CSI; ≥50 % improvement). Regression-adjusted mean total cost of care calculated on a per-member-per-year basis were then compared across the groups.</div></div><div><h3>Results</h3><div>The results indicated that relative to NI, CSI had incurred 36 % lower total cost of care (<em>p</em> = 0.032). However, no statistically significant association was found between NI and PI.</div></div><div><h3>Conclusion</h3><div>Although causal interpretations are difficult, these findings suggested clinically meaningful improvements in PHQ9 score are associated with lower total cost of care and that it is potentially feasible to develop a pay-for-performance scheme that align financial incentives with clinical outcomes. However, several barriers currently exist that prevent implementation in real-world settings.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"197 ","pages":"Article 112375"},"PeriodicalIF":3.3,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145019546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helena Liira, Mikko Varonen, Mikko S. Venäläinen, Jari Arokoski, Kirsi Kvarnström, Aki Vuokko, Antti Malmivaara
{"title":"Associations of socioeconomic status and health-related quality of life in patients with long COVID and patients with persistent physical symptoms: A comparison of two cohort studies at baseline","authors":"Helena Liira, Mikko Varonen, Mikko S. Venäläinen, Jari Arokoski, Kirsi Kvarnström, Aki Vuokko, Antti Malmivaara","doi":"10.1016/j.jpsychores.2025.112374","DOIUrl":"10.1016/j.jpsychores.2025.112374","url":null,"abstract":"<div><h3>Background and aim</h3><div>Emerging evidence suggest a significant association between Long COVID (LC) and other persistent physical symptoms (PPS) with lower socioeconomic status (SES). We investigated the relationship between SES and health-related quality of life (HRQOL), as measured by the 15D and the EUROHIS-QOL-8 instruments, among patients with LC and those experiencing other PPS-related conditions.</div></div><div><h3>Methods</h3><div>Factors related to clinical and socioeconomic aspects that affect HRQOL were evaluated using 15D, a validated 15-item self-reported questionnaire. Two parallel cohorts at Helsinki University Hospital were analyzed: the Helsinki LC cohort (<em>n</em> = 422; 2021–2023) and the Helsinki Sympa cohort (<em>n</em> = 599; 2020–2024), consisting of patients with PPS. Additionally, we performed an intersectional MAIHDA analysis of biopsychosocial predictors of quality of life.</div></div><div><h3>Results</h3><div>The cohorts were demographically similar, with 70.6 % and 66.4 % female participants and mean ages of 44.8 years (SD = 11.3) and 38.8 years (SD = 11.0) in the LC and Sympa cohorts, respectively. By EUROHIS-QOL-8, 34 % of LC and 41 % of Sympa respondents rated their overall QOL as very bad or bad (scale options 1–2 out of 5). Mean 15D scores were 0.76 (SD = 0.11) in the LC cohort and 0.74 (SD = 0.11) in the Sympa cohort (scale: 0–1). Working status, comorbidities, and tertiary education emerged as key determinants in the information-criteria–based model, highlighting the cumulative burden of overlapping social and clinical disadvantages. No significant multiplicative effects were found within our cohorts.</div></div><div><h3>Conclusions</h3><div>Patients in both cohorts reported reduced HRQOL, and the influence of socioeconomic factors on QOL were highly similar. Comorbidities, only basic school education, and being out of work were associated with the lowest HRQOL scores. The accumulation of socioeconomic disadvantage may function as a barrier to treatment, and healthcare professionals should recognize these challenges and ensure that patients receive adequate support.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"197 ","pages":"Article 112374"},"PeriodicalIF":3.3,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher M. Celano , Lily H. Jacobson , Emily H. Feig , Rachel A. Millstein , Wei-Jean Chung , Christina N. Massey , Brian C. Healy , Isabella Henneman , Monika Sadlonova , Nikita B. Acharya , Jeff C. Huffman
{"title":"A text message intervention to promote physical activity in midlife: The MASTERY randomized pilot trial","authors":"Christopher M. Celano , Lily H. Jacobson , Emily H. Feig , Rachel A. Millstein , Wei-Jean Chung , Christina N. Massey , Brian C. Healy , Isabella Henneman , Monika Sadlonova , Nikita B. Acharya , Jeff C. Huffman","doi":"10.1016/j.jpsychores.2025.112372","DOIUrl":"10.1016/j.jpsychores.2025.112372","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"197 ","pages":"Article 112372"},"PeriodicalIF":3.3,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emerson J. Bartholomew , Oleg N. Medvedev , Keith J. Petrie , Trudie Chalder
{"title":"Rasch analysis of the hospital anxiety and depression scale in patients with chronic fatigue syndrome","authors":"Emerson J. Bartholomew , Oleg N. Medvedev , Keith J. Petrie , Trudie Chalder","doi":"10.1016/j.jpsychores.2025.112370","DOIUrl":"10.1016/j.jpsychores.2025.112370","url":null,"abstract":"<div><h3>Background</h3><div>The Hospital Anxiety and Depression Scale (HADS) is widely utilized for assessing psychological distress in medical populations, yet its clinimetric properties in chronic fatigue conditions remain underexplored. Given the complex symptom presentation in chronic fatigue syndrome (CFS), rigorous clinimetric validation is essential for accurate clinical assessment.</div></div><div><h3>Objective</h3><div>This study aimed to evaluate the clinimetric properties of the HADS using Rasch methodology in patients with CFS, with particular emphasis on dimensionality, item functioning, and measurement precision.</div></div><div><h3>Methods</h3><div>Rasch analysis was conducted on HADS responses from 286 participants diagnosed with CFS. The Partial Credit Rasch model was applied to assess overall model fit, item performance, unidimensionality and differential item functioning.</div></div><div><h3>Results</h3><div>Initial analysis revealed suboptimal model fit, necessitating subtest modifications to address local response dependence. The subtest solution demonstrated acceptable fit to the Rasch model with evidence of strict unidimensionality, high reliability (PSI = 0.87), and no differential item functioning by demographic variables. Rasch-converted interval scores showed improved measurement precision compared to ordinal scoring. Interval scoring yielding a significantly higher mean (M = 22.55, SD = 3.78) compared to unconverted scoring (M = 20.30, SD = 6.87), <em>t</em>(275) = −19.54, <em>p</em> < .001, indicating that ordinal scoring systematically underestimates the latent trait level. Interval scores showed a 45 % reduction in measurement error demonstrated by the substantial reduction in standard error.</div></div><div><h3>Conclusions</h3><div>The HADS demonstrated acceptable measurement properties in patients with CFS. The development of ordinal-to-interval conversion tables enhances the scale's precision, supporting its continued use in clinical and research contexts.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"197 ","pages":"Article 112370"},"PeriodicalIF":3.3,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145049076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xuping Li , Shuiyuan Xiao , Yajun Sun , Ying Zheng , Yibin Hao , Gang Tian
{"title":"Path analysis of medication adherence in schizophrenia patients based on the extended theory of planned behavior: A cross-sectional study","authors":"Xuping Li , Shuiyuan Xiao , Yajun Sun , Ying Zheng , Yibin Hao , Gang Tian","doi":"10.1016/j.jpsychores.2025.112371","DOIUrl":"10.1016/j.jpsychores.2025.112371","url":null,"abstract":"<div><h3>Background</h3><div>Medication adherence is a significant challenge among community-dwelling patients with schizophrenia. Understanding the influencing factors through the lens of behavioral theory can provide valuable guidance for designing effective interventions to improve medication adherence.</div></div><div><h3>Objectives</h3><div>This study aimed to identify the factors associated with medication adherence and the underlying mechanisms, based on the extended Theory of Planned Behavior (TPB), among community-dwelling patients with schizophrenia in China.</div></div><div><h3>Methods</h3><div>Medication adherence was measured using the seven-day recall method. Medication attitudes were assessed using the Drug Attitude Inventory-10-Item Version, perceived behavioral control was measured with the Self-Efficacy for Appropriate Medication Use Scale, and subjective norms, intention, and supervision were evaluated using self-developed items. Path analysis was conducted to test the hypotheses based on the extended TPB.</div></div><div><h3>Results</h3><div>A total of 468 community-dwelling patients with schizophrenia were surveyed, and 81.20 % of them demonstrated adherent. Intention (standardized effect: 0.897) and supervision (standardized effect: 0.084) were directly associated with medication adherence. Attitude (standardized effect: 0.268, computed as 0.299 × 0.897), subjective norms (standardized effect: 0.283, computed as 0.316 × 0.897), and perceived behavioral control (standardized effect: 0.187, computed as 0.208 × 0.897) were indirectly associated with medication adherence through intention.</div></div><div><h3>Conclusion</h3><div>The extended TPB is a suitable model for predicting medication adherence among community-dwelling patients with schizophrenia in China. It provides a robust framework for designing interventions targeting attitude, subjective norms, perceived behavioral control, and supervision to enhance medication adherence.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"197 ","pages":"Article 112371"},"PeriodicalIF":3.3,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144932764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saya Niwa , Karolina Fila-Pawłowska , Tomasz Wieczorek , Arkadiusz Ziółkowski , Omer Van den Berg , Joanna Rymaszewska
{"title":"Differential autonomic reactivity and end-tidal CO2 levels in patients with persistent somatic symptoms versus healthy controls","authors":"Saya Niwa , Karolina Fila-Pawłowska , Tomasz Wieczorek , Arkadiusz Ziółkowski , Omer Van den Berg , Joanna Rymaszewska","doi":"10.1016/j.jpsychores.2025.112268","DOIUrl":"10.1016/j.jpsychores.2025.112268","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"196 ","pages":"Article 112268"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Dauchy , Cathy Bonnet , Clément Gouraud , Hélène Dechamps-Léger , Diana Bouaza , Jacques Blacher , Cédric Lemogne
{"title":"Evaluation of an integrative and collaborative program to support general practitioners in the Management of Post-Traumatic Stress Symptoms among refugee patients","authors":"Sarah Dauchy , Cathy Bonnet , Clément Gouraud , Hélène Dechamps-Léger , Diana Bouaza , Jacques Blacher , Cédric Lemogne","doi":"10.1016/j.jpsychores.2025.112240","DOIUrl":"10.1016/j.jpsychores.2025.112240","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"196 ","pages":"Article 112240"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ann-Christin Pfeifer , Eva Neubauer , Marcus Schiltenwolf
{"title":"Enhancing pain outcomes: The role of therapeutic alliance and biological markers in interdisciplinary multimodal pain therapy","authors":"Ann-Christin Pfeifer , Eva Neubauer , Marcus Schiltenwolf","doi":"10.1016/j.jpsychores.2025.112270","DOIUrl":"10.1016/j.jpsychores.2025.112270","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"196 ","pages":"Article 112270"},"PeriodicalIF":3.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145010602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}