Journal of Psychosomatic Research最新文献

{"title":"Incident mental disorders after breast cancer: A matched population-based cohort","authors":"Alzina Koric ,&nbsp;Chun-Pin Esther Chang ,&nbsp;N. Lynn Henry ,&nbsp;Mark Dodson ,&nbsp;Michael G. Newman ,&nbsp;Ankita P. Date ,&nbsp;Vikrant G. Deshmukh ,&nbsp;Mia Hashibe","doi":"10.1016/j.jpsychores.2025.112108","DOIUrl":"10.1016/j.jpsychores.2025.112108","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the risk of mental disorders and contributing factors of depression in breast cancer survivors, as well as to estimate the risk of death.</div></div><div><h3>Methods</h3><div>A total of 20,440 women diagnosed with breast cancer between 1997 and 2017 were identified in the Utah Cancer Registry and matched to a general population of women without cancer. To assess the risk of mental disorders and death following breast cancer, hazard ratios (HRs) and 99 % confidence intervals (CI) were estimated using Cox proportional-hazards models overall, within 2, &gt; 2 to 5, and &gt; 5-years of follow-up.</div></div><div><h3>Results</h3><div>Compared with women without cancer, breast cancer survivors had an elevated risk of depression notably within 2 years of follow-up for depression (HR 2.64, 99 %CI 2.43, 2.87), anxiety (HR 2.89, 99 %CI 2.66, 3.15), bipolar (HR 1.85, 99 %CI 1.45, 2.37), alcohol (HR 1.88, 99 %CI 1.43, 2.46), and substance-related disorders (HR 1.95, 99 %CI 1.59, 2.39). Although the risks were attenuated compared to the immediate follow-up, the burden of alcohol- and substance-disorders persisted within 5 and depression and anxiety &gt;5 years post cancer. Breast cancer survivors diagnosed with substance-related disorders within 2 years of cancer had a 2.3-fold higher risk of death (HR 2.28, 99 % CI 1.72, 3.03) compared to those without during the same time period. Depression predictors included obesity, ≥2 comorbidities, chemotherapy, or being separated.</div></div><div><h3>Conclusion</h3><div>Compared with women without cancer, breast cancer survivors had an elevated risk of multiple mental disorders. The risk of death was notably increased among breast cancer survivors with substance-related disorders.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112108"},"PeriodicalIF":3.5,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143715059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"The impact of photovoice on the report of emotions in individuals with persistent physical symptoms: Results of an experimental trial\" [Journal of Psychosomatic Research 191 (2025) 112069].","authors":"Selina Studer, Christina Nuhn, Cornelia Weise, Maria Kleinstäuber","doi":"10.1016/j.jpsychores.2025.112103","DOIUrl":"https://doi.org/10.1016/j.jpsychores.2025.112103","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":" ","pages":"112103"},"PeriodicalIF":3.5,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deciphering the complex interaction between depression, inflammation, and metabolism: A step forward but not the full picture","authors":"Pedro Lucas Santana da Silveira ,&nbsp;Antônia Gleiciane Marques Andrade ,&nbsp;Lia Mesquita de Abreu ,&nbsp;Samara Alves de Matos Angelim ,&nbsp;Emilly Sampaio de Lima ,&nbsp;Letícia Braga Martins ,&nbsp;Fabio Gomes de Matos e Souza","doi":"10.1016/j.jpsychores.2025.112105","DOIUrl":"10.1016/j.jpsychores.2025.112105","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112105"},"PeriodicalIF":3.5,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of different exercise types on depression and anxiety in individuals with cancer: A systematic review and network meta-analysis of randomized controlled trials","authors":"Peidong Wu ,&nbsp;Mengting Qian ,&nbsp;Xiangxu Chen ,&nbsp;Mingze Zhu ,&nbsp;Jing Liu","doi":"10.1016/j.jpsychores.2025.112107","DOIUrl":"10.1016/j.jpsychores.2025.112107","url":null,"abstract":"<div><h3>Objective</h3><div>Various exercise modalities have been demonstrated to be effective in alleviating anxiety and depression among individuals with cancer. However, it remains unclear which specific exercise intervention is the optimal choice. This study aimed to systematically evaluate the impact of different exercise intervention types on anxiety and depression in individuals with cancer.</div></div><div><h3>Methods</h3><div>Eligible randomized controlled trials were identified through searches of PubMed, Web of Science, and EBSCOHost, with the search period up to December 2024. Two researchers independently conducted the literature screening, data extraction, and assessment. Statistical analyses and visualizations were performed using Stata 15.0 software and RevMan5.4 software.</div></div><div><h3>Results</h3><div>A total of 26 randomized controlled trials (involving 2118 individuals with cancer) examining three types of exercise interventions were included. Compared to usual care, mind-body exercise (SMD = −0.58, 95 % CI (−0.99, −0.17)), followed by resistance training (SMD = −0.52, 95 % CI (−1.12, 0.09)), and aerobic exercise (SMD = −0.51, 95 % CI (−0.89, −0.13)) significantly decreased depression levels among individuals with cancer. Additionally, resistance training (SMD = −0.66, 95 % CI (−1.59, 0.27)), followed by aerobic exercise (SMD = −0.59, 95 % CI (−1.08, −0.10)), and mind-body exercise (SMD = −0.48, 95 % CI (−0.96, 0.00)) significantly decreased anxiety levels among individuals with cancer compared to usual care.</div></div><div><h3>Conclusion</h3><div>The findings of this network meta-analysis suggest that mind-body exercise, resistance training, and aerobic exercise are all effective interventions for reducing anxiety and depression among individuals with cancer.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112107"},"PeriodicalIF":3.5,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143704428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling the psychosocial links: How stressful life events and depression shape subjective aging in older adults?","authors":"Paul Arjanto ,&nbsp;Mint Husen Raya Aditama ,&nbsp;Feibry Feronika Wiwenly Senduk","doi":"10.1016/j.jpsychores.2025.112104","DOIUrl":"10.1016/j.jpsychores.2025.112104","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112104"},"PeriodicalIF":3.5,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143682295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of third-wave cognitive behavioural interventions on biopsychosocial outcomes in people diagnosed with advanced cancer: A systematic review and meta-analysis of randomised controlled trials","authors":"Elizabeth Beasley ,&nbsp;Victoria White ,&nbsp;Anna Ugalde ,&nbsp;Joanne Brooker ,&nbsp;David Skvarc ,&nbsp;Antonina Mikocka-Walus","doi":"10.1016/j.jpsychores.2025.112106","DOIUrl":"10.1016/j.jpsychores.2025.112106","url":null,"abstract":"<div><h3>Objective</h3><div>People with advanced cancer experience elevated psychological morbidity and poor quality of life (QoL). The role of third-wave cognitive-behavioural therapy (CBT) interventions in addressing these needs has been examined, but not synthesised in a systematic review. The aim of this review is to systematically identify, analyse and review randomised controlled trials (RCTs) which examined the effect of third-wave CBT interventions on biopsychosocial outcomes (e.g., anxiety, pain, QoL) in this population.</div></div><div><h3>Methods</h3><div>A systematic search was undertaken on MEDLINE, PsycInfo, CINAHL, Embase and Cochrane CENTRAL. Studies were included if they examined the effect of third-wave CBT interventions on biopsychosocial outcomes in adults living with advanced cancer in RCTs. The Cochrane Risk of Bias tool assessed risk of bias for each study. A random-effects model was fitted to the data and the restricted maximum-likelihood estimator was applied. The standardised mean differences (SMD) between control and experimental groups at short- and long-term follow up were used.</div></div><div><h3>Results</h3><div>Twelve RCTs with 782 participants were identified. Meta-analyses demonstrated that third-wave CBT interventions were only more effective than comparator groups in the short-term improvement of QoL (SMD = 0.19, 95 % CI [0.00, 0.37], <em>p</em> &lt; 0.05). The results of the 11 other meta-analyses did not reach statistical significance. Eight studies were classified as having unclear risk, and four were classified as high risk of bias.</div></div><div><h3>Conclusions</h3><div>Third-wave CBT interventions may be effective in enhancing QoL in people with advanced cancer. However, more rigorous RCTs are needed to establish their efficacy in this population.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112106"},"PeriodicalIF":3.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143682294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional neurological disorder and related conditions in healthcare provider education: A scoping review of teaching strategies and outcomes","authors":"Dearbhla P. Cullinane,&nbsp;Ashley Durfee,&nbsp;Neil Fleming,&nbsp;Denis S. Barry","doi":"10.1016/j.jpsychores.2025.112102","DOIUrl":"10.1016/j.jpsychores.2025.112102","url":null,"abstract":"<div><h3>Objective</h3><div>Limited awareness of functional neurological disorder (FND) and related conditions among healthcare providers is hindering early diagnosis and treatment. Enhancing knowledge of FND across medical curricula and in healthcare settings is vital for improving patient outcomes, yet few reports describe the implementation or impact of FND-related educational programmes.</div></div><div><h3>Methods</h3><div>Following PRISMA-ScR guidelines, EMBASE, MEDLINE Ovid, PsycINFO, CINAHL Ultimate, and Web of Science were searched from inception to 13 March 2024. The search term strategy included FND and related conditions combined with education for students and healthcare providers. Retrospective bibliography and grey literature searches were also conducted. Eligibility was guided using a PCC framework. Data were quantified by performing frequency counts, and a basic inductive qualitative content analysis identified facilitators and barriers to FND education. The Kirkpatrick model for evaluating training was used to stratify training outcomes.</div></div><div><h3>Results</h3><div>Following conduct of the search strategy, 3334 abstracts were identified. Twenty-two reports were included following the database search and two reports were identified via a retrospective bibliography search. Inter-rater reliability for title/abstract and full-text screening was Cohen's Kappa = 0.693 and 0.799, respectively. The reported training strategies were predominantly didactic lectures. Simulated doctor-patient role-play was frequently cited as a teaching strategy and qualitative analysis indicated that trainee participants place value on this approach. Training programmes were predominantly evaluated by recording participant reactions, engagement, and changes in knowledge and attitude towards the disorder and its treatment.</div></div><div><h3>Conclusions</h3><div>This scoping review offers the first comprehensive overview of educational strategies for FND and related conditions. The review highlights a lack of focused educational programmes and provides data to guide future pedagogical research.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112102"},"PeriodicalIF":3.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143682293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Somatic and mental distress as predictors of number of symptoms associated with environmental factors in an adult general population: Cross-sectional and longitudinal findings","authors":"Ferenc Köteles ,&nbsp;Steven Nordin","doi":"10.1016/j.jpsychores.2025.112098","DOIUrl":"10.1016/j.jpsychores.2025.112098","url":null,"abstract":"<div><h3>Objective</h3><div>Hypotheses were tested of associations between indicators of somatic and mental distress and number of different types of environmental intolerances, referred to as symptoms attributed to environmental factors (SAEFs), and these indicators predicting development of additional SAEFs in a general population. The SAEFs regarded chemicals, buildings, electromagnetic fields and sounds.</div></div><div><h3>Methods</h3><div>Data were used from a Swedish population-based sample of 2336 adults. Cross-sectional and 3-year longitudinal analyses were conducted based on validated questionnaire instruments assessing somatic symptom distress, perceived stress, anxiety and depression.</div></div><div><h3>Results</h3><div>Prevalence percentage of the SAEFs ranged from 2.1 % to 13.4 %; 16.2 % had one SAEF, 4.9 % had two SAEFs, and 1.2 % had three or four SAEFs. Cross-sectionally, Kendall rank correlation analyses and ANOVAs showed that somatic symptom distress (r_tau-b = 0.214), perceived stress (r_tau-b = 0.137), anxiety (r_tau-b = 0.145) and depression (r_tau-b = 0.100) increased with number of SAEF. In the longitudinal analysis, all four indicators were found to be predictors of an increase in number of SAEFs three years later (odds ratios = 1.021–1.049 for each scale step), with somatic symptom distress as the strongest predictor.</div></div><div><h3>Conclusion</h3><div>The results suggest that all four types of SAEFs are associated with all four indicators of negative affectivity, and that the level of these indicators is associated with number of SAEFs and predict development of additional SAEFs. Among the studied indicators, somatic symptom distress appears to be particularly associated with development of multiple SAEFs, perhaps driven by the motive to find a cause for bothersome symptoms (misattribution).</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112098"},"PeriodicalIF":3.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating branched-chain amino acids and risk of psychiatric disorders: A two-sample Mendelian randomization study","authors":"Xueren Gao,&nbsp;Weichao Zhang,&nbsp;Fang Wang","doi":"10.1016/j.jpsychores.2025.112101","DOIUrl":"10.1016/j.jpsychores.2025.112101","url":null,"abstract":"<div><h3>Objective</h3><div>Several studies have identified biomarkers that help in the prevention, diagnosis, and treatment of psychiatric disorders. The current study aimed to explore the association between circulating branched-chain amino acids (BCAA) and the risk of five psychiatric disorders.</div></div><div><h3>Methods</h3><div>GWAS summary statistics were obtained from the UK Biobank and the FinnGen Biobank. The inverse variance weighted (IVW) method was used as a primary method to assess causal effects. The heterogeneity test, the horizontal pleiotropy test, and leave-one-out analysis were used to assess the robustness and reliability of the results.</div></div><div><h3>Results</h3><div>Total BCAA levels were not significantly associated with the risk of anxiety disorders, alcohol dependence, depression, panic disorder, and bipolar affective disorders. Separate analyses for each BCAA showed that the levels of valine and leucine were not associated with the risk of the mentioned five psychiatric disorders, and the levels of isoleucine were not associated with the risk of depression, panic disorder, and bipolar affective disorders, but with the risk of anxiety disorders (IVW: OR = 0.814, 95 %CI = 0.716–0.925) and alcohol dependence (IVW: 0.690, 95 %CI = 0.560–0.849).</div></div><div><h3>Conclusions</h3><div>Circulating isoleucine was a protective factor for anxiety disorders and alcohol dependence, offering a new research direction and theoretical basis for preventing and managing psychiatric disorders.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112101"},"PeriodicalIF":3.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of hands-off approaches alone or in combination with hands-on approaches in the treatment of chronic cervical pain within a biopsychosocial framework: A systematic review","authors":"Kübra Canlı ,&nbsp;Charbel Najem ,&nbsp;Jessica Van Oosterwijck ,&nbsp;Mira Meeus ,&nbsp;Kayleigh De Meulemeester","doi":"10.1016/j.jpsychores.2025.112086","DOIUrl":"10.1016/j.jpsychores.2025.112086","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to systematically review the current literature comparing hands-off approaches with hands-on approaches from a biopsychosocial perspective of pain processing in people suffering from chronic primary neck pain (CPNP).</div></div><div><h3>Methods</h3><div>An electronic search was conducted on PubMed, Web of Science, Scopus, and Cochrane Library. Initial searches were carried out in November 2022, with electronic database searches repeated on November 25, 2024. Eligibility criteria which were randomized controlled trials comparing hands-off approaches alone or in combination with hands-on approaches and hands-on approaches alone in people with CPNP were checked by two independent authors. The risk of bias was assessed using the revised Cochrane Risk of Bias Tool (RoB). The strength of conclusion was determined using the evidence-based guideline development approach.</div></div><div><h3>Results</h3><div>Fifteen studies with a total of 1029 participants were included in this review. The RoB was rated as low RoB for two studies, some concerns for two studies and high RoB for 11 studies.</div><div>Pain processing was assessed by pain intensity(100 % of the studies), pain sensitivity(53 % of the studies), pain-related participation in social roles(46 % of the studies), pain-related emotions(26 % of the studies), and pain-related beliefs(6 % of the studies). Limited quality of evidence was found for the hands-off approaches alone being more effective on pain intensity than hands-on approaches alone in the long term. Limited- to moderate-quality of evidence was found for hands-off approaches combined with hands-on approaches, being more effective than hands-on approaches alone in improving pain intensity, pain sensitivity, pain-related participation in social roles, pain-related emotions, and pain-related beliefs in the short-, mid- or long-term.</div></div><div><h3>Conclusions</h3><div>The current findings suggest that hands-off approaches alone are superior to hands-on approaches in the long term, at least for pain intensity. Hands-off approaches in combination with hands-on approaches were also more effective than hands-on approaches for pain processing. However, substantial heterogeneity warrants a cautious interpretation of these results. More high-quality, randomized, controlled trials with homogenous data collection and larger sample sizes are needed.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112086"},"PeriodicalIF":3.5,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143643595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}