The role of self-compassion in protecting psychological wellbeing and health-related quality of life in those with endometriosis: A prospective study

IF 3.5 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research Pub Date : 2025-07-09 DOI:10.1016/j.jpsychores.2025.112322

Chelsea M. Skinner, Roeline G. Kuijer

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引用次数: 0

Abstract

Objective

Endometriosis negatively impacts psychological wellbeing and health-related quality of life (HRQoL). Emerging research suggests that self-compassion may be a protective resource, although the mechanisms through which it influences functioning in endometriosis are not well understood. This study examined the relationship between self-compassion, psychological distress, and HRQoL over a six-month period. Pain catastrophising, pain acceptance, and resilience were examined as potential mediators.

Methods

264 individuals with endometriosis completed questionnaires twice over a 6-month period assessing self-compassion (T1 only), psychological distress (depression, anxiety, and stress), HRQoL, pain catastrophising, pain acceptance (activity engagement, pain willingness), resilience, and endometriosis-related information (T1 and T2). Bootstrapped mediation analyses were conducted to examine the relationship between the key variables cross-sectionally and over time (two-wave mediation).

Results

Psychological wellbeing and HRQoL was significantly impaired in this sample. Higher self-compassion was associated with less impairment on all outcome variables at T1 (r > −0.25, p < .001) and improvements in depression (b = −0.28, p < .01) and stress (b = −0.21, p < .05) over the study period. Cross-sectionally, pain catastrophising mediated the relationship between self-compassion and all outcome variables. Prospectively, higher self-compassion at baseline was related to a decrease in pain catastrophising over the study period, which in turn was related to a decrease in depression, anxiety, stress, and HRQoL impairment over the study period. Pain willingness, activity engagement, and resilience were less consistent mediators at baseline and did not mediate the relationship between self-compassion and the outcome variables prospectively.

Conclusion

Future research should consider interventions that address self-compassion and pain catastrophising to reduce impairment in psychological wellbeing and HRQoL in individuals with endometriosis.

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自我同情在子宫内膜异位症患者保护心理健康和健康相关生活质量中的作用：一项前瞻性研究

目的子宫内膜异位症对心理健康和健康相关生活质量（HRQoL）有负面影响。新兴研究表明，自我同情可能是一种保护资源，尽管它影响子宫内膜异位症功能的机制尚不清楚。这项研究在六个月的时间里调查了自我同情、心理困扰和HRQoL之间的关系。疼痛灾难化、疼痛接受和恢复力被认为是潜在的中介。方法264例子宫内膜异位症患者在6个月内完成两次问卷调查，评估自我同情（T1）、心理困扰（抑郁、焦虑和压力）、HRQoL、疼痛灾难、疼痛接受（活动参与、疼痛意愿）、恢复力和子宫内膜异位症相关信息（T1和T2）。进行了自举中介分析，以横向和随时间检验关键变量之间的关系（双波中介）。结果本组患者心理健康状况和HRQoL均明显下降。较高的自我同情与T1时所有结果变量的损害程度降低相关(r >；−0.25,p <；.001)和抑郁症的改善(b = - 0.28, p <；.01)和应力(b = - 0.21, p <；.05)。横断面上，疼痛灾难化介导了自我同情与所有结果变量之间的关系。前瞻性地，基线时较高的自我同情与研究期间疼痛灾难的减少有关，而疼痛灾难又与研究期间抑郁、焦虑、压力和HRQoL损害的减少有关。疼痛意愿、活动投入和恢复力在基线时是不一致的中介，并且在自我同情与结果变量之间没有前瞻性的中介作用。结论未来的研究应考虑自我同情和痛苦灾难的干预措施，以减少子宫内膜异位症患者心理健康和HRQoL的损害。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Psychosomatic Research 医学-精神病学

CiteScore

7.40

自引率

6.40%

发文量

314

审稿时长

6.2 weeks

期刊介绍： The Journal of Psychosomatic Research is a multidisciplinary research journal covering all aspects of the relationships between psychology and medicine. The scope is broad and ranges from basic human biological and psychological research to evaluations of treatment and services. Papers will normally be concerned with illness or patients rather than studies of healthy populations. Studies concerning special populations, such as the elderly and children and adolescents, are welcome. In addition to peer-reviewed original papers, the journal publishes editorials, reviews, and other papers related to the journal''s aims.