Journal of Psychosomatic Research最新文献

{"title":"Short report: Early-onset health anxiety: Insights from a cross-sectional study on adults diagnosed with severe health anxiety","authors":"Rebecca Nyengaard ,&nbsp;Katrine Ingeman ,&nbsp;Lisbeth Frostholm ,&nbsp;Charlotte Ulrikka Rask","doi":"10.1016/j.jpsychores.2025.112127","DOIUrl":"10.1016/j.jpsychores.2025.112127","url":null,"abstract":"<div><h3>Objective</h3><div>The knowledge of early-onset health anxiety (HA) (i.e. onset before age 18) is limited. This retrospective study aimed to investigate 1) the age of onset of HA and 2) potential clinical factors associated with early- compared with late-onset HA in adult patients with severe HA.</div></div><div><h3>Methods</h3><div>The study sample consisted of 126 adults (aged 20–60 years) diagnosed with severe HA and referred to specialized treatment. All underwent semi-structured diagnostic interviews assessing psychiatric disorders and functional somatic disorders. The interview also included a detailed illness history with a chronological listing of HA symptom onset. Self-reports were obtained on current HA symptoms, illness perceptions, and treatment expectations.</div></div><div><h3>Results</h3><div>Early onset of HA was reported by 40 participants (32 %, 95 % CI: 24 %–41 %) with a mean age at symptom onset of 11.6 years (SD: 4.0, range: 5–17), and 23 participants reported onset before age 13 (57.5 %). Early-onset HA was significantly associated with more negative perceptions of consequences of symptoms (Cohen's d = 0.41, <em>p</em> = 0.04) and stronger psychological attributions (Cohen's d = 0.33, <em>p</em> = 0.03), and the group with early onset were more often diagnosed with severe functional somatic disorders (Cramer's V = 0.17, <em>p</em> = 0.06) and reported more negative treatment expectations (Cramer's V = 0.17, p = 0 0.06), although these results were non-significant.</div></div><div><h3>Conclusion</h3><div>Early onset of HA may be common and associated with more negative illness perceptions in adulthood. These results need replication but highlight the need for further research on HA in youth.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112127"},"PeriodicalIF":3.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Who benefits the most from cognitive behavior therapy for health anxiety? Secondary analysis of a randomized controlled trial of internet-delivered vs. face-to-face treatment in primary care","authors":"Erland Axelsson ,&nbsp;Erik Andersson ,&nbsp;Daniel Björkander ,&nbsp;Maria Hedman-Lagerlöf ,&nbsp;Susanna Österman ,&nbsp;Jonna Hybelius ,&nbsp;Erik Hedman-Lagerlöf","doi":"10.1016/j.jpsychores.2025.112130","DOIUrl":"10.1016/j.jpsychores.2025.112130","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate who benefits most from exposure-focused cognitive behavior therapy (CBT) for pathological health anxiety.</div></div><div><h3>Methods</h3><div>This was a secondary study based on a randomized controlled trial of Internet-delivered versus face-to-face CBT (<em>N</em> = 204) delivered in primary care for participants with pathological health anxiety and a primary diagnosis of either somatic symptom disorder or illness anxiety disorder. Linear mixed effects regression models were fitted on 13 weekly 18-item Health Anxiety Inventory assessments over the treatment phase. The time×variable coefficient was tested as indicative of a predictive effect, regardless of treatment format. The treatment format (Internet versus face-to-face) was then added to the model, and the time×format×variable coefficient was tested as indicative of moderation of the between-format effect. The following pre-treatment variables were evaluated: age, gender, education, health anxiety, subtypes of health anxiety behaviors, anxiety sensitivity, intolerance of uncertainty, depression symptoms, experience of psychotherapy, noncommunicable disease, treatment preference, and path of referral.</div></div><div><h3>Results</h3><div>Regardless of delivery format, a larger reduction in health anxiety was predicted by higher pre-treatment health anxiety, bodily preoccupation/checking, prevention/planning, anxiety sensitivity, and depression symptoms. Most effects were small. None of the candidate variables were significant moderators of the relative effect of Internet-delivered and face-to-face CBT.</div></div><div><h3>Conclusion</h3><div>This study replicates that higher pre-treatment health anxiety and anxiety sensitivity are predictive of a larger reduction in health anxiety regardless of CBT format. So far, no robust moderators of the relative effect of Internet-delivered versus face-to-face CBT for health anxiety have been identified.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112130"},"PeriodicalIF":3.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143800057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Amalia et al. “Health anxiety, academic procrastination, and the SDGs: A call for longitudinal research and global collaboration”","authors":"Charlotte Steen Duholm","doi":"10.1016/j.jpsychores.2025.112126","DOIUrl":"10.1016/j.jpsychores.2025.112126","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112126"},"PeriodicalIF":3.5,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and tinnitus: Evidence from a nationally representative observational study","authors":"Ying Cui ,&nbsp;Wenjie Miao ,&nbsp;Tong Wu ,&nbsp;Chenyang Liu ,&nbsp;Lin Chen","doi":"10.1016/j.jpsychores.2025.112114","DOIUrl":"10.1016/j.jpsychores.2025.112114","url":null,"abstract":"<div><h3>Background</h3><div>Tinnitus, a condition with substantial psychological and physical implications, significantly impacts quality of life; however, its relationship with lipid metabolism remains underexplored.</div></div><div><h3>Methods</h3><div>This population-based observational study included 4991 participants. Weighted multivariate logistic regression and restricted cubic spline (RCS) analyses were employed to assess the relationship between the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and tinnitus. Subgroup and sensitivity analyses were conducted to evaluate the consistency and robustness of findings across sociodemographic and health-related subgroups.</div></div><div><h3>Results</h3><div>A total of 791 participants reported tinnitus, with a prevalence of 15.85 %. A significant positive association was observed between NHHR and tinnitus risk. In the final model with all covariates adjusted, when NHHR increased by one unit, the risk of tinnitus would increase by 12 % (odds ratio [OR] = 1.12, 95 % confidence interval (CI), 1.02–1.22, <em>P</em> = 0.022). Compared to the lowest NHHR tertile, the highest NHHR tertile had a higher risk of tinnitus (OR = 1.46; 95 % CI, 1.02–2.07, <em>P</em> = 0.040). RCS analysis revealed that NHHR was linearly associated with tinnitus (<em>P</em> for nonlinearity = 0.923). Subgroup analyses confirmed that this association remained stable across various sociodemographic and health subgroups (<em>P</em> for interaction &gt;0.05).</div></div><div><h3>Conclusions</h3><div>These findings suggest that NHHR is positively and linearly associated with tinnitus risk, highlighting the essential role of NHHR in the development of tinnitus. The findings underscore the need for integrated metabolic and psychosomatic approaches in tinnitus prevention and management.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112114"},"PeriodicalIF":3.5,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Causal relationship between graves’ disease and mental disorders: A bidirectional Mendelian randomization study","authors":"Yuanyuan Deng ,&nbsp;Zejin Hao ,&nbsp;Wen Chen ,&nbsp;Junping Zhang ,&nbsp;Yun Zou ,&nbsp;Jie Zhang ,&nbsp;Yanhua Xi ,&nbsp;Jixiong Xu","doi":"10.1016/j.jpsychores.2025.112124","DOIUrl":"10.1016/j.jpsychores.2025.112124","url":null,"abstract":"<div><h3>Objective</h3><div>Many patients with Graves' disease (GD) also suffer from mental disorders in clinical practice, but their causal relationship remains unclear. This study aims to investigate the causal relationship between GD and common mental disorders using a bidirectional Mendelian randomization (MR)approach.</div></div><div><h3>Methods</h3><div>We derived genome-wide association study (GWAS) data for common mental disorders, including major depressive disorder (MDD), anxiety disorders, bipolar disorder, and attention-deficit/hyperactivity disorder (ADHD), from the Psychiatric Genomics Consortium consortium. GWAS data for GD were obtained from the FinnGen consortium. Subsequently, a bidirectional MR analysis was conducted, with the inverse-variance weighted (IVW) methods as the primary MR analysis method. Sensitivity analysis used Cochran's Q test, MR-Egger intercept test, and leave-one-out method.</div></div><div><h3>Results</h3><div>IVW results in MR demonstrated a positive association between genetic susceptibility to GD and bipolar disorder (OR = 1.073, 95 % CI: 1.042–1.105, <em>p</em> = 2.882 × 10⁻⁶). Similar causal estimates were obtained through MR-Egger regression and the weighted median method. Additionally, both Cochran's Q test and MR-Egger intercept test indicated no evidence of heterogeneity or pleiotropy. However, no causal associations were demonstrated between GD and MDD, anxiety disorders, or ADHD. Furthermore, a causal relationship between genetic susceptibility to common mental disorders and GD was not evidenced.</div></div><div><h3>Conclusions</h3><div>This bidirectional MR study supports the role of GD in the causal association with an increased risk of bipolar disorder, which guides us to pay attention to the mental diseases of GD patients in the clinic.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112124"},"PeriodicalIF":3.5,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Journal of Psychosomatic Research 2024 year in review.","authors":"Jess G Fiedorowicz, Antonina Mikocka-Walus","doi":"10.1016/j.jpsychores.2025.112125","DOIUrl":"https://doi.org/10.1016/j.jpsychores.2025.112125","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":" ","pages":"112125"},"PeriodicalIF":3.5,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143788908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protecting young women's body image from appearance-based social media exposure: A comparative study of self-compassion writing and mindful breathing interventions","authors":"Enying Li ,&nbsp;Wanni Cheng ,&nbsp;Hong Yuan ,&nbsp;Xiao Gao","doi":"10.1016/j.jpsychores.2025.112121","DOIUrl":"10.1016/j.jpsychores.2025.112121","url":null,"abstract":"<div><h3>Objective</h3><div>This study compared the effectiveness of self-compassion writing and mindful breathing in protecting body image after exposure to appearance-focused social media. It focused on individuals with high self-objectification and explored the underlying mechanisms and emotional benefits of these interventions.</div></div><div><h3>Methods</h3><div>A randomized controlled trial was conducted with 107 young females (17–25 years) assigned to self-compassion writing (<em>n</em> = 37), mindful breathing (<em>n</em> = 36), or control (<em>n</em> = 34) groups. Body dissatisfaction was induced using idealized body imagery, after which participants completed their respective interventions. State body image was measured at baseline, post-induction, and post-intervention. At the end of the study, a semi-structured interview was conducted, and the data were analyzed using Neff's self-compassion framework.</div></div><div><h3>Results</h3><div>A two-way ANOVA revealed a significant interaction effect between group and time point <em>F</em> (3.98, 207.15) = 8.45, <em>p</em> &lt; 0.001, partial <em>η</em>^<em>2</em> = 0.140. Self-compassion writing through enhanced self-kindness improved state body image beyond baseline levels. Trait self-objectification moderated the efficacy of the intervention (<em>∆R</em>^<em>2</em> = 0.04, <em>F</em> (2,100) = 3.48, <em>p</em> = 0.035). Mediation analysis revealed that both interventions improved emotional state through body image enhancement (mediation effect size = 0.21).</div></div><div><h3>Conclusions</h3><div>Self-compassion writing demonstrated superior efficacy over mindful breathing, primarily through fostering self-kindness. Body image emerged as a critical mediator of emotion improvement, highlighting the value of mindfulness-based interventions in promoting body positivity and emotional resilience following appearance-based social media exposure.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112121"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143799979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of clinical characteristics and prognosis of childhood functional neurological disorder: Identifying key factors of prognosis and optimizing clinical management","authors":"Anqi Wang ,&nbsp;Xiaowen Yang ,&nbsp;Yu Tian ,&nbsp;Hua Yang ,&nbsp;Rong Luo","doi":"10.1016/j.jpsychores.2025.112120","DOIUrl":"10.1016/j.jpsychores.2025.112120","url":null,"abstract":"<div><h3>Background</h3><div>To explore and analyze the clinical characteristics of childhood functional neurological disorder (FND) and identify key factors influencing the prognosis to optimize clinical practice.</div></div><div><h3>Method</h3><div>In this retrospective study, clinical data of children with FND who visited the Department of Pediatric Neurology of West China Second Hospital of Sichuan University between March 2020 and March 2023 were collected to analyze their clinical characteristics and prognosis. And 173 patients completed follow-up one year after diagnosis. Logistic regression was used to analyze factors associated with clinical prognosis.</div></div><div><h3>Results</h3><div>Among the 248 patients, with a median age of 10 years (IQR 9–12), 60.5 % were male and 39.5 % were female. The most common symptoms were weakness or paralysis and non-epileptic seizures. 11.2 % combined with psychiatric disorders. Half of the patients had experienced previous stressors, including personal (40.3 %), family (22.6 %), and school factors (21.0 %). The average follow-up time was 488.7 ± 295.5 days. The overall prognosis was good, with clinical symptom remission in 75.1 % of cases. Logistic regression revealed that both the duration of symptoms and comorbid psychiatric disorders were negatively associated with a good prognosis.</div></div><div><h3>Conclusion</h3><div>The clinical characteristics of children with FND may be associated with socio-cultural background factors and psychological factors. Symptom duration and comorbid psychiatric disorders are important factors influencing prognosis.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112120"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143760932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health anxiety, academic procrastination, and the SDGs: A call for longitudinal research and global collaboration","authors":"Riza Amalia ,&nbsp;Henny Indreswari ,&nbsp;I.M. Hambali ,&nbsp;Arbin Janu Setiyowati ,&nbsp;Rizky Andana Pohan ,&nbsp;Ronal Surya Aditya ,&nbsp;Rosalia Dewi Nawantara ,&nbsp;Surahman","doi":"10.1016/j.jpsychores.2025.112111","DOIUrl":"10.1016/j.jpsychores.2025.112111","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112111"},"PeriodicalIF":3.5,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143747347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"I'm tired of pretending that nothing's wrong: A mixed-methods study of financial barriers for individuals living with primary dysmenorrhea","authors":"Kathryn Wilkin ,&nbsp;Subhadra Evans ,&nbsp;Marilla Druitt ,&nbsp;Antonina Mikocka-Walus","doi":"10.1016/j.jpsychores.2025.112119","DOIUrl":"10.1016/j.jpsychores.2025.112119","url":null,"abstract":"<div><h3>Background</h3><div>Primary dysmenorrhea (PD), or pain in the abdomen experienced during menstruation, remains under-recognised, leading to poorer financial outcomes for those affected.</div></div><div><h3>Aim</h3><div>The current study aimed to explore individual perspectives of financial burden relating to PD, while also examining the impact of biopsychosocial factors on reported financial barriers.</div></div><div><h3>Method</h3><div>Participants completed an online survey between May and July 2019 measuring pain, symptoms of depression, anxiety, and stress, fatigue, perceived social support, sociodemographic information, days of work or school missed, and number of GP or specialist visits due to pain per year. Open-ended questions relating to financial impact of PD and suggested workplace supports were included in a two-year follow-up survey. Template thematic analysis was conducted, and themes were then entered as outcome measures in binary logistic regression models, using biopsychosocial variables as predictors.</div></div><div><h3>Results</h3><div>Australian women who experienced PD, measured by a numeric rating scale for period pain, were recruited (<em>n</em> = 140). Three themes were developed: <em>Burden of Healthcare and Financial Disempowerment</em>, <em>Reduced Workplace Participation</em> and <em>Stigma and Prejudice</em>. Pain (OR = 1.568, 95 % CI = 1.195–2.058), fatigue (OR = 1.050, 95 % CI = 1.013–1.089) and perceived family support (OR = 0.715, 95 % CI = 0.522–0.980) significantly predicted <em>Stigma and Prejudice</em>.</div></div><div><h3>Conclusion</h3><div>Increased pain or fatigue severity and reduced perceived family support may be associated with <em>Stigma and Prejudice</em> as a financial barrier for those with PD. Improved recognition of the impact of PD at a governmental level may help to address stigma, thus reducing the financial burden for those affected and society as a whole.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"192 ","pages":"Article 112119"},"PeriodicalIF":3.5,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}