Journal of Psychosomatic Research最新文献

{"title":"Post-traumatic stress disorder and risk of systemic lupus erythematosus: Meta-analysis and Mendelian randomization study","authors":"Lingfeng Chen ,&nbsp;Mengge Zhang ,&nbsp;Shate Xiang ,&nbsp;Jingjing Zhang ,&nbsp;Runyu Chang ,&nbsp;Chao Hu ,&nbsp;Suhai Qian ,&nbsp;Ting Liu ,&nbsp;Yufeng Shi ,&nbsp;Xinghong Ding","doi":"10.1016/j.jpsychores.2025.112049","DOIUrl":"10.1016/j.jpsychores.2025.112049","url":null,"abstract":"<div><h3>Objective</h3><div>We conducted a meta-analysis and Mendelian randomization study to analyze the association and causal relationship of genetic prediction between post-traumatic stress disorder and the risk of systemic lupus erythematosus.</div></div><div><h3>Methods</h3><div>A meta-analysis was conducted using hazard ratio, relative risk, odds ratio, and 95 % confidence intervals as effect measures. Summary data from genome-wide association studies on post-traumatic stress disorder and systemic lupus erythematosus were utilized to assess the causal relationship of genetic prediction between post-traumatic stress disorder and systemic lupus erythematosus using Mendelian randomization.</div></div><div><h3>Results</h3><div>A meta-analysis showed that post-traumatic stress disorder was positively associated with the risk of systemic lupus erythematosus (RR = 1.85, 95 % CI = 1.61–2.12, <em>p</em> &lt; 0.001). The results of Egger's test showed no publication bias (<em>p</em> = 0.823, <em>p</em> &gt; 0.05). Sensitivity analysis showed that the meta-analysis results were stable (RR = 1.85, 95 % CI = 1.61–2.12). However, Mendelian Randomization analysis revealed no evidence of a causal relationship of genetic prediction between post-traumatic stress disorder and systemic lupus erythematosus (IVW OR: 1.001, 95 % CI: 0.805–1.245, <em>p</em> = 0.993).</div></div><div><h3>Conclusion</h3><div>There is a correlation between post-traumatic stress disorder and systemic lupus erythematosus, but Mendelian Randomization does not support a genetic causal effect of post-traumatic stress disorder on systemic lupus erythematosus. The potential causal relationship between the two factors may necessitate further in-depth research.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"190 ","pages":"Article 112049"},"PeriodicalIF":3.5,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing cognitive functions in non-neuropsychiatric childhood systemic lupus erythematosus: Cross-sectional study","authors":"Emil Aliyev ,&nbsp;Ecem Selin Akbas Aliyev ,&nbsp;Selcan Demir ,&nbsp;Mubeccel Yeniada Kirseven ,&nbsp;Cihat Celik ,&nbsp;Ozlem Kahraman Erkus ,&nbsp;Halime Tuna Cak Esen ,&nbsp;Ebru Cengel Kultur ,&nbsp;Banu Anlar ,&nbsp;Seza Ozen ,&nbsp;Yelda Bilginer","doi":"10.1016/j.jpsychores.2024.112027","DOIUrl":"10.1016/j.jpsychores.2024.112027","url":null,"abstract":"<div><h3>Objectives</h3><div>Systemic Lupus Erythematosus (SLE) is an autoimmune disease characterized by multisystem, including neuropsychiatric, involvement. The nervous system is affected in 20–27 % of patients within approximately two years after diagnosis. This study aimed to examine neurocognitive impairment in childhood-onset SLE (cSLE) patients before the development of any neurological, psychiatric, or cognitive manifestations.</div></div><div><h3>Methods</h3><div>The study included 98 children and adolescents. Of these, 34 (35 %) were cSLE groups, and the remaining formed two control groups: 31 (31 %) oligoarticular Juvenile Idiopathic Arthritis (oJIA) patients served as a “patient control” group, and 33 (34 %) healthy participants socio-demographically matched to the cSLE and oJIA patients formed the healthy control (HC) group. None of the subjects in the study exhibited neurological or psychiatric symptoms.</div></div><div><h3>Results</h3><div>The Wechsler Intelligence Scale for Children-IV (WISC-IV) was applied to all groups. Test results showed that the Perceptual Reasoning Index Score (PRIS) was significantly lower in cSLE than in HC (F(2, 95) = 3.365, <em>p</em> = 0.042, Tukey HSD: <em>p</em> = 0.01). ‘Comprehension’ subtest scores were significantly lower in the cSLE group compared to the HC group (H(2) = 8.133, <em>p</em> = 0.017; U = 352.5, <em>p</em> = 0.009). Similarly, ‘symbol search’ subtest scores were significantly lower in the cSLE group compared to the HC group (F(2, 95) = 3.545, <em>p</em> = 0.036, Tukey HSD: <em>p</em> = 0.014).</div></div><div><h3>Conclusion</h3><div>Our results revealed that cSLE may have neurocognitive impairment without presenting any symptoms. Early detection is possible with the neurocognitive test WISC-IV. These results support the inclusion of objective neurocognitive assessment methods into the routine clinical follow-up of childhood-onset SLE.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112027"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive behavioural therapy versus other interventions on mental health in people with sensory impairments: A systematic review and meta-analysis","authors":"M. Trott ,&nbsp;A. Koblitz ,&nbsp;S. Pardhan","doi":"10.1016/j.jpsychores.2024.111998","DOIUrl":"10.1016/j.jpsychores.2024.111998","url":null,"abstract":"<div><h3>Background</h3><div>Sensory impairments can negatively affect people's quality of life and daily functioning, including anxiety and depression symptoms. Cognitive behavioural therapy (CBT) could be an effective intervention to alleviate these, however its effectiveness compared to other interventions have not been examined. The aim of this review was to examine the effectiveness of CBT versus other interventions on anxiety and depression symptoms in people with hearing, visual, and other sensory impairments.</div></div><div><h3>Methods</h3><div>This systematic review and meta-analysis of randomised controlled trials (RCTs) was conducted using a pre-registered protocol (Prospero ID:CRD42023425953). Searches were conducted in across six databases from inception through October 2024. Random-effects meta-analyses were performed.</div></div><div><h3>Results</h3><div>Of 18 included studies, interventions for tinnitus yielded a significant effect favouring intervention on anxiety (Hedge's <em>g</em> = 0.5;95 %CI0.3–0.9) and depression symptoms (Hedge's <em>g</em> = 0.4; 95 %CI 0.1–0.6). Interventions for people with hearing loss not related to tinnitus yielded a significant effect favouring intervention on anxiety symptoms (Hedge's <em>g</em> = 0.6;95 %CI 0.2–1.1), but not in depression symptoms (Hedge's <em>g</em> = 0.3;95 %CI -0.0;0.6). When sub-grouped, no significant differences between CBT and other interventions were found. Interventions for people with vision impairment yielded a non-significant difference in depression symptoms (Hedge's <em>g</em> = 0.4;95 %CI -0.0;0.7), with no studies found examining anxiety symptoms.</div></div><div><h3>Conclusion</h3><div>No significant differences were found when comparing CBT versus other interventions in hearing loss. The effectiveness of CBT for people with visual impairment was less clear due to a small number of studies. Future studies should consider other types of sensory impairments.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 111998"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142796159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modulation of cardiac autonomic activity across consciousness states and levels of sleep depth in individuals with sleep complaints and bipolar disorder or unipolar depressive disorders","authors":"Chloe Leveille ,&nbsp;Mysa Saad ,&nbsp;Daniel Brabant ,&nbsp;David Birnie ,&nbsp;Karina Fonseca ,&nbsp;Elliott Kyung Lee ,&nbsp;Alan Douglass ,&nbsp;Georg Northoff ,&nbsp;Katerina Nikolitch ,&nbsp;Julie Carrier ,&nbsp;Stuart Fogel ,&nbsp;Caitlin Higginson ,&nbsp;Tetyana Kendzerska ,&nbsp;Rebecca Robillard","doi":"10.1016/j.jpsychores.2024.111996","DOIUrl":"10.1016/j.jpsychores.2024.111996","url":null,"abstract":"<div><h3>Objective</h3><div>Autonomic nervous system dysfunction and reduced heart rate variability (HRV) often co-exist with mood disorders, a phenomenon likely influenced by sleep disturbances. This study investigated heart rate (HR) and HRV across wake, rapid eye movement (REM) sleep, and non-REM (NREM) sleep in individuals with sleep complaints and bipolar or unipolar depressive disorder.</div></div><div><h3>Methods</h3><div>Polysomnographic data was retrospectively collated for 120 adult patients with sleep complaints and depressive symptoms [60 diagnosed with bipolar disorder, 60 diagnosed with a unipolar depressive disorder], and 60 healthy controls. HR and time-based HRV variables were computed on 30-s segments and averaged across the night for wake, NREM and REM sleep.</div></div><div><h3>Results</h3><div>Significant group by consciousness state interactions showed that the unipolar and bipolar groups had lower standard deviation of normal-to-normal intervals root mean square of successive R-R interval differences compared to controls during NREM and REM sleep, but not during wake (SDNN: <em>F</em>(4, 330) = 3.0, <em>p</em> = .021, np2 = 0.035; RMSSD: <em>F</em>(4, 332) = 5.8, <em>p &lt;</em> .001, np2 = 0.065). The magnitude of these group differences did not vary significantly between NREM 1, NREM 2 and NREM 3 sleep. These interactions persisted after excluding individuals taking 3rd generation antipsychotic, lithium, anticonvulsant, and cardiovascular medications.</div></div><div><h3>Conclusion</h3><div>Although further work is required to account for the impact of psychotropic and cardiac medications, as well as manic and euthymic states, these findings suggest that the sleep-based autonomic signature of depressive states differs across different types of mood disorders and could potentially inform the development of biomarkers and therapeutic targets.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 111996"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between personality traits and myocardial infarction- A European cross-sectional study","authors":"Björn Agvall ,&nbsp;Junmei Miao Jonasson","doi":"10.1016/j.jpsychores.2024.112019","DOIUrl":"10.1016/j.jpsychores.2024.112019","url":null,"abstract":"<div><h3>Background</h3><div>Myocardial infarction (MI) is a serious condition that increases with age. It is valuable to identify the reasons why some are affected, and possibly, why different personality traits can be associated with an increased or decreased risk for myocardial infarction.</div></div><div><h3>Methods</h3><div>This is a cross-sectional study based on wave 7 data from the Survey of Health, Ageing and Retirement in Europe (SHARE). A total of 52,231 individuals aged 50 years or older were included in the study. The Big Five personality traits constituted the main exposure variables and were analyzed separately. The value of each personality trait variable was standardized. The association between each personality trait and MI was examined by logistic regression models which were used to estimate the Odds Ratios (ORs) and 95 % Confidence Intervals (CIs).</div></div><div><h3>Results</h3><div>A total of 6336 participants reported having a MI in this study. The odds of MI were higher in individuals with greater Neuroticism (OR: 1.15, 95 % CI: 1.12–1.18). Higher Conscientiousness was associated with decreased odds of MI (OR: 0.96, 95 % CI: 0.94–0.99). Higher Agreeableness was associated with lower odds of MI (OR: 0.96, 95 % CI: 0.94–0.99). There were no significant associations between Openness or Extraversion and the odds of MI, respectively.</div></div><div><h3>Conclusions</h3><div>Higher Neuroticism was associated with increased odds of MI. Higher Agreeableness and Conscientiousness were associated with decreased odds of MI, respectively. Our study is of interest for the prevention of MI.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112019"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Boosting integration of physical and mental health: The impact of increasing psychiatrists in general hospitals without psychiatric Ward","authors":"Michitaka Funayama ,&nbsp;Toshihiro Taira ,&nbsp;Yoshinori Saeki ,&nbsp;Keiichi Uemura ,&nbsp;Fumie Oka ,&nbsp;On Kato ,&nbsp;Naoko Satake ,&nbsp;Hiraki Koishikawa ,&nbsp;Shigeki Sato ,&nbsp;Katsuji Nishimura","doi":"10.1016/j.jpsychores.2024.112024","DOIUrl":"10.1016/j.jpsychores.2024.112024","url":null,"abstract":"<div><h3>Objective</h3><div>It remains unclear whether general hospitals without psychiatric wards can provide sufficient services for both physical and mental health needs, as they often lack adequate psychiatrists, primarily due to cost constraints. This article explores the relationship between the number of full-time psychiatrists and functionality for integrating physical and mental health services in these settings.</div></div><div><h3>Methods</h3><div>The Medical Policy Committee of the Japanese Society of General Hospital Psychiatry conducted a nationwide survey in 2022 to evaluate the detailed scope and volume of service of psychiatric departments in general hospitals without a psychiatric ward. The survey collected data related to scope and volume of service, including the availability of on-call services, the number of patients seen in outpatient settings, and the number of consultation-liaison services provided. The results were analyzed based on the number of full-time psychiatrists, with and without data from university hospitals, and categorized by hospital type. To account for confounding factors, multivariable regression analyses were also performed.</div></div><div><h3>Results</h3><div>Broader scope and higher vollume in essential services was observed depending on the number of full-time psychiatrists, including on-call services, outpatient services, and consultation-liaison services, especially pediatric, anorexia, and perinatal psychiatric issues. Hospitals with multiple full-time psychiatrists offered broader services, a scope beyond the capacity of a single full-time psychiatrist, as confirmed by multivariable analyses. University hospitals offered the widest range of psychiatric services.</div></div><div><h3>Conclusions</h3><div>Despite often being underestimated due to cost constraints, having multiple full-time psychiatrists in a general hospital without a psychiatric ward is essential for supporting the broader scope needed to integrate physical and mental health services.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112024"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of depressive symptoms and cardiovascular health with mortality among U.S. adults","authors":"Boxuan Pu ,&nbsp;Wei Wang ,&nbsp;Lubi Lei ,&nbsp;Jingkuo Li ,&nbsp;Yue Peng ,&nbsp;Yanwu Yu ,&nbsp;Lihua Zhang ,&nbsp;Xin Yuan","doi":"10.1016/j.jpsychores.2024.112032","DOIUrl":"10.1016/j.jpsychores.2024.112032","url":null,"abstract":"<div><h3>Background</h3><div>Depression and cardiovascular health (CVH) are interconnected, and both are independently associated with mortality. However, the joint effects of depressive symptoms and CVH on mortality remain unclear.</div></div><div><h3>Methods</h3><div>By utilizing the National Health and Nutrition Examination Survey (NHANES) 2007–2018, we included 18,679 adults aged ≥20 years without cardiovascular diseases (CVD). The definition of elevated depressive symptoms was based on the Patient Health Questionnaire-9 (PHQ-9) scores≥10. CVH was evaluated by Life's Essential 8 (LE8) and categorized into low (&lt;50), moderate (50–80), or high (≥80). The joint association of depressive symptoms and CVH with mortality was examined utilizing multivariate Cox proportional hazard models.</div></div><div><h3>Results</h3><div>Elevated depressive symptoms were associated with higher mortality risks, and CVH could explain 12.7 % and 13.7 % of the associations between depression and all-cause and non-CVD mortality, respectively. No significant interactions were found between CVH and depressive symptoms on mortality. High CVH attenuated the all-cause mortality risk in patients with elevated depressive symptoms (HR, 0.20; 95 % CI: 0.05–0.89). Compared to participants with elevated depressive symptoms and low CVH, those with no elevated depressive symptoms and high CVH had lower risks of all-cause (HR, 0.26; 95 % CI: 0.16–0.43), CVD (HR, 0.20; 95 % CI: 0.07–0.52), non-CVD mortality (HR, 0.28; 95 % CI 0.16–0.50).</div></div><div><h3>Conclusion</h3><div>Adults with low CVH and elevated depressive symptoms had significantly higher risks of all-cause, CVD, and non-CVD mortality. The finding suggests considering depressive symptoms and CVH jointly in developing targeted strategies to improve survival.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112032"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An online mindfulness-based intervention for adults with Inflammatory Bowel Disease & psychological distress: A feasibility randomized controlled trial of the Mind4IBD program","authors":"Colette Naude ,&nbsp;David Skvarc ,&nbsp;Yao Coitinho Biurra ,&nbsp;Lily Blake ,&nbsp;Subhadra Evans ,&nbsp;Simon Knowles ,&nbsp;O. Eric ,&nbsp;Chatpakorn Prasertsung ,&nbsp;Lahiru Russell ,&nbsp;Anna Bassili ,&nbsp;Antonina Mikocka-Walus","doi":"10.1016/j.jpsychores.2024.111984","DOIUrl":"10.1016/j.jpsychores.2024.111984","url":null,"abstract":"<div><h3>Objective</h3><div>The bidirectional relationship between disease activity and mental health in inflammatory bowel disease (IBD) has prompted investigations into the efficacy of psychotherapies, such as mindfulness-based interventions (MBI), for improving biopsychosocial outcomes. Therefore, the aim is to examine the feasibility, acceptability, and preliminary efficacy of an online-delivered, self-directed MBI, adapted to individuals with IBD and psychological distress, in comparison to wait-list control (WLC).</div></div><div><h3>Methods</h3><div>50 adults with IBD were randomized to WLC (<em>N</em> = 25) or intervention (N = 25) groups. The intervention (MIND4IBD program) consisted of six, weekly, 15-min videos (with guided meditations). Feasibility was examined through recruitment and retention rates, while acceptability was examined through intervention satisfaction ratings and qualitative feedback. Preliminary efficacy was examined using linear mixed models for group differences in outcomes between baseline and post-intervention.</div></div><div><h3>Results</h3><div>Primary Outcomes. The retention rate for the WLC group was 92 %, while the retention rate for the intervention group was 48 %. However, 16 % of participants allocated to the intervention group never began the intervention, therefore this resulted in a retention rate of 71 % of participants who began the intervention. Acceptability was high with an average intervention satisfaction rating of 83/100. Secondary Outcomes. When compared with the WLC, the MIND4IBD program improved total mindfulness levels (b = 0.29, 95 %CI [0.11,0.47], <em>p</em> = 0.004) with a large effect size (β = 0.54, b = 0.19, 95 %CI [0.04,0.34], <em>p</em> = 0.014). Themes based on participants' intervention feedback included: 1) beginning of journey with mindfulness, 2) the beneficial impact of mindfulness, 3) why adapting the intervention to IBD is important, 4) views on program delivery, and 5) mixed reactions to AI generated presenters.</div></div><div><h3>Conclusion</h3><div>MIND4IBD is feasible and acceptable for individuals with IBD and psychological distress. Participants' total mindfulness levels increased significantly in the intervention group compared to WLC. Most participants provided positive intervention feedback. These findings warrant a full-scale RCT to determine MIND4IBD's efficacy for IBD.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 111984"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of post-stroke delirium with short-term trajectories of cognition","authors":"Elzbieta Klimiec-Moskal,&nbsp;Joanna Pera,&nbsp;Agnieszka Slowik,&nbsp;Tomasz Dziedzic","doi":"10.1016/j.jpsychores.2024.112011","DOIUrl":"10.1016/j.jpsychores.2024.112011","url":null,"abstract":"<div><h3>Background</h3><div>Delirium could increase the risk of cognitive decline. We aimed to determine if changes in cognitive functions shortly after stroke differ between patients with and patients without delirium.</div></div><div><h3>Methods</h3><div>We included patients who participated in the Prospective Observational Polish Study on post-stroke delirium and underwent the Montreal Cognitive Assessment (MoCA) at day 1, day 8 and 3 months after stroke. Delirium was diagnosed using DSM-5 criteria. We used mixed linear regression models to characterize changes in mean adjusted MoCA scores over time.</div></div><div><h3>Results</h3><div>We included 402 patients (mean age: 68.9 <span><math><mo>±</mo></math></span> 13.3 years; mean NIHSS on admission: 6.2 <span><math><mo>±</mo></math></span> 5.5; 48.8 % female). Delirium occurred in 18.9 % of them. Mean adjusted MoCA scores increased from day 1 to day 8 (20.48 vs 23.34, <em>P</em> &lt; 0.001) and then declined from day 8 to month 3 (23.34 vs 22.21, P &lt; 0.001). The rate of change in total MoCA scores from day 1 to day 8 (net effect: 0.65, 95 %CI: −1.19; 2.49, <em>P</em> = 0.489) and from day 8 to month 3 (net effect: -2.43, 95 %CI: −4.84; −0.02, <em>P</em> = 0.147) did not differ between patients with and patients without delirium. Compared with patients without delirium, those with delirium showed a greater improvement in naming, orientation and attention, accompanied by a worsening in memory from day 1 to day 8. They also experienced a greater decline in attention and orientation, along with a greater improvement in memory from day 8 to 3 months.</div></div><div><h3>Conclusions</h3><div>Post-stroke delirium is associated with short-term trajectories of specific cognitive domains, but not with changes in global cognition.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112011"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neighborhood disorder and social cohesion: A longitudinal investigation of links with maternal cardiometabolic risk one year postpartum","authors":"Leah Cha,&nbsp;Amanda K. Montoya,&nbsp;Christine Dunkel Schetter,&nbsp;Jennifer A. Sumner","doi":"10.1016/j.jpsychores.2024.112012","DOIUrl":"10.1016/j.jpsychores.2024.112012","url":null,"abstract":"<div><h3>Objective</h3><div>Neighborhood characteristics can influence cardiometabolic health, including during the perinatal period. However, maternal health research has largely examined the influence of objective neighborhood measures, limiting insights into psychological and social processes. We examined associations of perceived neighborhood disorder and social cohesion with maternal cardiometabolic risk 1 year postpartum and explored potential pathways of psychological distress and physical activity.</div></div><div><h3>Methods</h3><div>A predominantly low-income sample of Black, Latina, and White postpartum women (<em>n</em> = 987) were participants in the Community Child Health Network study. Women reported on neighborhood characteristics at 1 month postpartum and on symptoms of depression, anxiety, and posttraumatic stress disorder and physical activity at 6 months postpartum. Biometrics and biological samples were collected at 1 year postpartum, including blood pressure, height, weight, and dried blood spots for cardiometabolic biomarkers (e.g., C-reactive protein, glycosylated hemoglobin). In this pre-registered study, we used structural equation modeling to estimate latent variables for disorder, social cohesion, distress, physical activity, and cardiometabolic risk. We fit a parallel mediation model to test associations between latent neighborhood factors at 1 month postpartum, distress and physical activity at 6 months postpartum, and cardiometabolic risk at 1 year postpartum.</div></div><div><h3>Results</h3><div>Greater social cohesion, but not disorder, was significantly associated with lower distress and greater physical activity. However, there were no significant associations between disorder or social cohesion with subsequent cardiometabolic risk nor evidence for indirect effects of distress or physical activity.</div></div><div><h3>Conclusion</h3><div>Results suggest that social cohesion may be more pertinent than disorder for health-relevant behavioral mechanisms in postpartum women.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"189 ","pages":"Article 112012"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}