Shanshan Yang , Yujie Ma , Hang Fu , Chengzeng Wang , Yafeng Zhang
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引用次数: 0
Abstract
Objective
This study examined the association between allostatic load and trouble sleeping and assessed whether this relationship varies based on allostatic load score (ALS) criteria.
Methods
This cross-sectional survey utilized nationally representative data from the National Health and Nutrition Examination Survey (NHANES). ALS was derived using empirical and clinical criteria based on eight biomarkers reflecting cardiovascular, metabolic, and immune function. Weighted multivariate logistic regression was employed to analyze the association between ALS and trouble sleeping, with subgroup analyses conducted to assess gender-specific differences.
Results
Of 5331 participants included in this study, 1485 (29 %) reported trouble sleeping. In multivariate-adjusted logistic regression, higher ALS was associated with increased odds of trouble sleeping (empirical ALS: OR 1.13 [95 % CI 1.07–1.18]; clinical ALS: OR 1.08 [95 % CI 1.04–1.13]). Subgroup analyses confirmed the consistency of this association across genders.
Conclusion
This study provides robust evidence of a significant association between ALS and trouble sleeping, supported by observed OR of 1.13 (empirical) and 1.08 (clinical). The consistency of findings across both empirical and clinical ALS underscores the potential role of physiological dysregulation in sleep health, highlighting the need for integrated approaches to stress and sleep management.
目的本研究探讨了适应负荷与睡眠困难之间的关系,并评估这种关系是否根据适应负荷评分(ALS)标准而变化。方法本横断面调查采用了全国健康与营养检查调查(NHANES)中具有全国代表性的数据。ALS是根据经验和临床标准得出的,基于反映心血管、代谢和免疫功能的八种生物标志物。采用加权多变量逻辑回归分析ALS与睡眠障碍之间的关系,并进行亚组分析以评估性别差异。结果在5331名参与者中,1485人(29%)报告有睡眠问题。在多变量调整logistic回归中,ALS越高与睡眠困难的几率增加相关(经验ALS: OR 1.13 [95% CI 1.07-1.18];临床ALS: OR 1.08 [95% CI 1.04-1.13])。亚组分析证实了这种关联在不同性别之间的一致性。结论本研究提供了强有力的证据,证明ALS与睡眠困难之间存在显著关联,观察到的OR值为1.13(经验)和1.08(临床)。经验和临床ALS研究结果的一致性强调了生理失调在睡眠健康中的潜在作用,强调了压力和睡眠管理综合方法的必要性。
期刊介绍:
The Journal of Psychosomatic Research is a multidisciplinary research journal covering all aspects of the relationships between psychology and medicine. The scope is broad and ranges from basic human biological and psychological research to evaluations of treatment and services. Papers will normally be concerned with illness or patients rather than studies of healthy populations. Studies concerning special populations, such as the elderly and children and adolescents, are welcome. In addition to peer-reviewed original papers, the journal publishes editorials, reviews, and other papers related to the journal''s aims.