Lieselotte Mond , Martina de Zwaan , Batoul Safieddine , Kai G. Kahl , Jona T. Stahmeyer , Jelena Epping
{"title":"Incidence of depression in patients with chronic cardiovascular diseases: Case-control study with German health insurance claims data","authors":"Lieselotte Mond , Martina de Zwaan , Batoul Safieddine , Kai G. Kahl , Jona T. Stahmeyer , Jelena Epping","doi":"10.1016/j.jpsychores.2025.112066","DOIUrl":"10.1016/j.jpsychores.2025.112066","url":null,"abstract":"<div><h3>Background</h3><div>Depression and cardiovascular diseases (CVD) are two common conditions that account for a high proportion of morbidity and mortality worldwide and in Germany. The objective of this study is to examine whether the risk of developing depression in persons with prevalent chronic CVD is elevated compared to persons without CVD and whether it varies by sex and age group.</div></div><div><h3>Methods</h3><div>This observational case-control study is based on German statutory health insurance claims data from 2015 to 2019 (<em>N</em> = 2,229,042). The study population comprises persons with a CVD diagnosis in 2016 and without depression or acute major CVD event in 2015–2016 (<em>N</em> = 173,774). A control group was built by 1:1 matching by sex, gender and age. Cox regression models estimated the risk of developing depression during the observation period (2017–2019) while adjusting for several comorbidities. Results are presented stratified by sex and age group.</div></div><div><h3>Results</h3><div>The presence of chronic CVD increased the risk of developing depression in men and women and in all examined age groups. This relationship between chronic CVD and depression appeared to be particularly pronounced in younger men aged under 55 years (HR = 1.33, 95 %-Confidence Interval (CI) = 1.14–1.54). However, risk of developing depression was much higher in women (with and without CVD) than in men (HR = 1.53, 95 %-CI = 1.46–1.61).</div></div><div><h3>Conclusions</h3><div>This study underlines the importance of mental health services for patients with cardiovascular diseases. Given the impact of depression on re-hospitalization, self-care and all-mortality in patients with chronic cardiovascular disorders, a screening for depressive symptoms in this patient group is highly recommended.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"191 ","pages":"Article 112066"},"PeriodicalIF":3.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"‘Help yourself, so the (circadian) rhythms help you’: Chronobiological insights to promote physical and mental health","authors":"Roberto Manfredini , Filippo Pigazzani , Gianluca Colussi , Fiammetta Cosci","doi":"10.1016/j.jpsychores.2025.112072","DOIUrl":"10.1016/j.jpsychores.2025.112072","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"191 ","pages":"Article 112072"},"PeriodicalIF":3.5,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xilin Yu , Yueshuai Pan , Qianqian Li , Ruting Gu , Wenbin Jiang , Guofang Kuang , Lili Wei
{"title":"Development and validation of gestational diabetes mellitus health behaviour scale","authors":"Xilin Yu , Yueshuai Pan , Qianqian Li , Ruting Gu , Wenbin Jiang , Guofang Kuang , Lili Wei","doi":"10.1016/j.jpsychores.2025.112083","DOIUrl":"10.1016/j.jpsychores.2025.112083","url":null,"abstract":"<div><h3>Objective</h3><div>We aimed to develop the health behaviour scale for gestational diabetes mellitus patients (HB-GDM) and evaluate its psychometric properties. The scale may provide theoretical basis and evidence for identifying the pathways to enhance health behaviours and optimise health management strategies.</div></div><div><h3>Methods</h3><div>The initial constructs and items of the scale were developed through literature review, qualitative analysis and Delphi expert consultation based on the socio-ecological model. Item analysis was conducted by four methods and using a sample (<em>n</em> = 235) recruited in China to form formal scale. Additional participants (<em>n</em> = 505) completed survey to measure the internal consistency reliability, test-retest reliability, content validity, construct validity and criterion-related validity of scale.</div></div><div><h3>Results</h3><div>The scale contains six dimensions with a total of 29 items. The Cronbach's α of the scale was 0.912, McDonald's ω of the scale was 0.936, test–retest reliability was 0.957, content validity was 0.935, The cumulative variance contribution rate of the six common factors was 77.488 % and CFA model had acceptable goodness-of-fit indices(<em>χ</em><sup><em>2</em></sup><em>/df</em> = 2.567, <em>RMSEA</em> = 0.079). The criterion-related validity was 0.827(<em>P</em><0.01).</div></div><div><h3>Conclusion</h3><div>HB-GDM scale showed satisfactory psychometric properties and has strong specialisation and better applicability.</div></div><div><h3>Practice implications</h3><div>The scale is favourable for pregnant women with GDM to clarify their unhealth behaviours. It provided guidance regarding maternal and postpartum follow-up care and the formulation of women health care strategies with regional characteristics.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"191 ","pages":"Article 112083"},"PeriodicalIF":3.5,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143478588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martin Jirásek , Tomáš Sieger , Gabriela Chaloupková , Lucia Nováková , Petr Sojka , Mark J. Edwards , Tereza Serranová
{"title":"The impact of motor and non-motor symptoms fluctuations on health-related quality of life in people with functional motor disorder","authors":"Martin Jirásek , Tomáš Sieger , Gabriela Chaloupková , Lucia Nováková , Petr Sojka , Mark J. Edwards , Tereza Serranová","doi":"10.1016/j.jpsychores.2025.112071","DOIUrl":"10.1016/j.jpsychores.2025.112071","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the effect of overall, between- and within-day subjectively rated fluctuations in motor and non-motor symptoms in people with functional motor disorder (FMD) on the health-related quality of life (HRQoL).</div></div><div><h3>Background</h3><div>FMD is a complex condition characterized by fluctuating motor and non-motor symptoms that may negatively impact HRQoL.</div></div><div><h3>Methods</h3><div>Seventy-seven patients (54 females, mean age 45.4 ± 10.4 years) with a clinically established diagnosis of FMD, including weakness, completed symptom diaries, rating the severity of motor and non-motor symptoms (i.e., pain, fatigue, mood, cognitive difficulties) on a 10-point numerical scale three times daily for seven consecutive days. HRQoL was assessed using the SF-36 questionnaire. For the analysis, fluctuation magnitude was defined in terms of the variability in self-reported symptom scores.</div></div><div><h3>Results</h3><div>The mental component of SF-36 was jointly predicted by the overall severity scores (t(74) = −3.61, <em>P</em> < 0.001) and overall general fluctuations (t(74) = −2.98, <em>P</em> = 0.004). The physical SF-36 was found to be related only to the overall symptom severity scores (t(74) = −7.09, <em>P</em> < 0.001), but not to the overall fluctuations. The assessment of the impact of different components showed that the mental component of SF-36 was significantly influenced by the combined effect of average fatigue (t(73) = −3.86, <em>P</em> < 0.001), between-day cognitive symptoms fluctuations (t(73) = −3.22, <em>P</em> = 0.002), and within-day mood fluctuations (t(73) = −2.48, <em>P</em> = 0.015).</div></div><div><h3>Conclusions</h3><div>This study demonstrated the impact of self-reported symptom fluctuations across multiple motor and non-motor domains on mental but not physical HRQoL in FMD and highlighted the importance of assessing and managing fluctuations in clinical practice.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"191 ","pages":"Article 112071"},"PeriodicalIF":3.5,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143478587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marjorie Heule , Mark A. Lumley , Janice Tomakowsky , Britney Abro , Laura Krasean
{"title":"Associations of abuse experiences in childhood/adolescence and adulthood to pain, sexual functioning, and mental health among women with urogenital pain","authors":"Marjorie Heule , Mark A. Lumley , Janice Tomakowsky , Britney Abro , Laura Krasean","doi":"10.1016/j.jpsychores.2025.112060","DOIUrl":"10.1016/j.jpsychores.2025.112060","url":null,"abstract":"<div><h3>Objective</h3><div>Urogenital pain affects 14–25 % of women and is predicted by prior abuse. The purpose of this study was to investigate associations of abuse type (sexual, physical, emotional, verbal) and timing (childhood, adolescence, adulthood) on outcomes (depression, anxiety, pain, sexual functioning).</div></div><div><h3>Methods</h3><div>Women (<em>N</em> = 350; age <em>M</em> = 48.44) presenting with pain at a tertiary women's urology center reported whether they had experienced each type of abuse at each time point and completed outcome measures.</div></div><div><h3>Results</h3><div>Latent class analysis of abuse types and timings identified a 4-class solution which differed primarily in phase of life for which abuse types (verbal, emotional, and physical, but not sexual) were elevated: 1) little or no abuse throughout life (66.6 %), 2) childhood/adolescent abuse only (14.6 %), 3) adulthood abuse only (8.3 %), or 4) abuse across the life course (10.6 %). Statistical comparisons between classes revealed abuse throughout life or in childhood/adolescence only was associated with depression and abuse throughout life, with anxiety <em>(p</em> < .001, <em>d</em> = 0.48–1.40), compared to no abuse. However, abuse over life or in adulthood only, but not childhood/adolescent only, was associated with pain interference, pain intensity, and low sexual satisfaction (<em>p</em> < .05, <em>d</em> = 0.38–0.77).</div></div><div><h3>Conclusion</h3><div>These patterns suggest that <em>when</em> abuse occurs may matter differentially in terms of mental and physical health; abuse (especially emotional/verbal and physical) in both childhood and adulthood may predispose to poor mental health, whereas adulthood abuse may be more associated with pain and functioning. One should assess when abuse occurs—including adulthood—in addition to type of abuse to understand its association with outcomes.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"191 ","pages":"Article 112060"},"PeriodicalIF":3.5,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of substance use disorders among patients with psoriasis and anxiety disorders","authors":"Nina Modanlo , Xiaofeng Yan , James A. Bourgeois","doi":"10.1016/j.jpsychores.2025.112068","DOIUrl":"10.1016/j.jpsychores.2025.112068","url":null,"abstract":"","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"191 ","pages":"Article 112068"},"PeriodicalIF":3.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143463420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Selina Studer , Christina Nuhn , Cornelia Weise , Maria Kleinstäuber
{"title":"The impact of photovoice on the report of emotions in individuals with persistent physical symptoms: Results of an experimental trial","authors":"Selina Studer , Christina Nuhn , Cornelia Weise , Maria Kleinstäuber","doi":"10.1016/j.jpsychores.2025.112069","DOIUrl":"10.1016/j.jpsychores.2025.112069","url":null,"abstract":"<div><h3>Objective</h3><div>Identifying and reporting emotions can be challenging for individuals with persistent physical symptoms (PPS), like tinnitus or tension-type headaches. Photovoice (PV) helps people identify and report their emotions by photographing relevant objects or situations. The aim of our study was to examine whether PV facilitates the report of emotions in individuals with PPS.</div></div><div><h3>Methods</h3><div>We randomly assigned 169 participants with PPS to one of three groups: a PV group, a writing group, or a passive control group. The PV group took daily photographs related to their symptoms and coping, the writing group wrote keywords, and the passive control group had no task. After a week, all participants completed an online writing task about their symptoms and coping, which was analyzed for the number of emotion words used. We also assessed self-reported affect, ability to identify and report emotions, and self-disclosure.</div></div><div><h3>Results</h3><div>Participants in the PV group used more emotion words in the writing task than the control groups. Specifically, the PV group used significantly more positive emotion words (<em>F</em>(2,166) = 26.86, <em>p</em> < .001) and fewer negative emotion words (<em>F</em>(2,166) = 8.28, <em>p</em> < .001) compared to the writing and control groups. No significant group differences were found for self-reported affect and self-disclosure.</div></div><div><h3>Conclusions</h3><div>PV promises to facilitate more positive, nuanced, and detailed reporting of emotions and may be therapeutically useful in gathering richer insights from the participant's perspective. Future research should target individuals who respond best to PV and develop tailored treatment to increase treatment effects.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"191 ","pages":"Article 112069"},"PeriodicalIF":3.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143550159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yun-shan Chen , Ge-hui Feng , Qian-qian Yue , Yi-Fei Wang , Min Liu , Ke-hao Zhao , Tian Tang , Mao-ting Huang , Wen-ting Yi , Hui-ling Yan , Jia-hui Yan , Ying Zeng
{"title":"Effects of non-pharmacological interventions on anxiety in patients undergoing colonoscopy: A network meta-analysis of randomized controlled trials","authors":"Yun-shan Chen , Ge-hui Feng , Qian-qian Yue , Yi-Fei Wang , Min Liu , Ke-hao Zhao , Tian Tang , Mao-ting Huang , Wen-ting Yi , Hui-ling Yan , Jia-hui Yan , Ying Zeng","doi":"10.1016/j.jpsychores.2025.112065","DOIUrl":"10.1016/j.jpsychores.2025.112065","url":null,"abstract":"<div><h3>Background</h3><div>Anxiety is a common and significant problem in patients who need to undergo colonoscopy. However, the question of which non-pharmacological intervention is the best strategy to reduce anxiety in patients undergoing colonoscopy remains unanswered.</div></div><div><h3>Objectives</h3><div>To evaluate and rank the effectiveness of various non-pharmacological interventions for reducing anxiety in patients undergoing colonoscopy in order to identify the most effective strategies.</div></div><div><h3>Methods</h3><div>We searched PubMed, Cochrane Library, Embase, Web of Science, and Medline for randomized controlled trials published from the database construction to March 2024. The primary outcome was the difference between pre- and post-intervention anxiety means. A network meta-analysis was conducted utilizing the “gemtc” package based on R4.3.0.</div></div><div><h3>Results</h3><div>The analysis encompassed 24 randomized controlled trials, incorporating 2525 participants and evaluating 9 non-pharmacological interventions. All non-pharmacological interventions reduced anxiety in patients undergoing colonoscopy compared to standard care, with music intervention (SMD = -0.52, 95 %CI (−0.84,-0.20)), audiovisual distraction (SMD = -0.54, 95 %CI(−0.96,-0.12)), video information (SMD = -1.47, 95 %CI(−2.03,-0.90)), individual education (SMD = -1.72, 95 %CI(−2.76,-0.70)), and electroacupuncture (SMD = -1.12, 95 %CI(−2.10,-0.13)) having statistically significant effects. SUCRA ranking identified the priority of individual education (SUCRA: 92.5 %) and video information (SUCRA: 87.7 %). Meta-regression and sensitivity analysis further demonstrated the stability of the evidence. The certainty of the evidence was mostly rated as medium to low.</div></div><div><h3>Conclusion</h3><div>This review highlights the superior effects of individual education and video information in reducing anxiety in patients undergoing colonoscopy. The findings of our review could provide clinical decision-makers and healthcare practitioners, such as doctors and nurses, with evidence-based practices for selecting interventions to reduce anxiety in patients undergoing colonoscopy.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"191 ","pages":"Article 112065"},"PeriodicalIF":3.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143550158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhaojun Yang , Yehao Luo , Jiali He , Yahui Yuan , Qiaoyun Liu , Jingyi Guo , Yuping Lin , Lu Sun , Guanjie Fan
{"title":"Association between weekend catch-up sleep and the systemic immune-inflammation index in adults: Evidence from the NHANES 2017–2020","authors":"Zhaojun Yang , Yehao Luo , Jiali He , Yahui Yuan , Qiaoyun Liu , Jingyi Guo , Yuping Lin , Lu Sun , Guanjie Fan","doi":"10.1016/j.jpsychores.2025.112070","DOIUrl":"10.1016/j.jpsychores.2025.112070","url":null,"abstract":"<div><h3>Background</h3><div>Chronic sleep deprivation is widespread and associated with detrimental health outcomes, including inflammation. A common strategy to address weekday sleep deficits is weekend catch-up sleep (WCS). However, the relevance of the WCS on systemic inflammation, as quantified by the systemic immune-inflammation index (SII), remains inadequately understood.</div></div><div><h3>Methods</h3><div>This cross-sectional analysis examined data from the National Health and Nutrition Examination Survey (NHANES) 2017–2020 cohort. To explore the relationship between the WCS and the SII, we employed univariate analysis, weighted linear regression, restricted cubic spline (RCS) techniques, and subgroup analyses.</div></div><div><h3>Results</h3><div>The final sample included 4849 adults. Weighted linear regression confirmed a negative association between the WCS and the SII after adjusting for potential confounders (β = −16.72, 95 % CI: −34.29 to 0.85, <em>P</em> = 0.04). Subgroup analyses revealed that this association varied by obesity, gender, and age. Additionally, the association between the WCS duration and the SII was non-linear (<em>P</em> = 0.006) in adults with a weekday sleep duration of 7–8 h.</div></div><div><h3>Conclusion</h3><div>WCS can help mitigate the inflammatory burden associated with chronic sleep deprivation. WCS durations of 3 h and longer are particularly beneficial for adults who experience sleep deprivation on weekdays. The association between WCS and SII appears to be moderated by factors such as obesity, gender, and smoking status.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"191 ","pages":"Article 112070"},"PeriodicalIF":3.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143463419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoo Hyun Um , Jihye Oh , Young-Chan Kim , Suhyung Kim , Tae-Won Kim , Ho-Jun Seo , Jong-Hyun Jeong , Seung-Chul Hong
{"title":"Sex and age-related differences of the mental health risk in obstructive sleep apnea: A nationwide population-based cohort study","authors":"Yoo Hyun Um , Jihye Oh , Young-Chan Kim , Suhyung Kim , Tae-Won Kim , Ho-Jun Seo , Jong-Hyun Jeong , Seung-Chul Hong","doi":"10.1016/j.jpsychores.2025.112064","DOIUrl":"10.1016/j.jpsychores.2025.112064","url":null,"abstract":"<div><h3>Background</h3><div>Obstructive sleep apnea (OSA) and psychiatric disorders often coexist, affecting patient outcomes and treatment responses. This relationship, particularly the risk of psychiatric conditions in OSA patients, merits further investigation considering age and sex differences.</div></div><div><h3>Methods</h3><div>Utilizing the South Korean National Health Insurance claims database (2010–2019), this nationwide-population-based, retrospective study identified OSA patients and matched them with controls based on age and sex. Psychiatric disorders were defined using ICD-10 codes for depression and anxiety. Multivariable logistic regression models, adjusted for demographics and comorbidities, evaluated the association between OSA and psychiatric disorders, with detailed subgroup analyses by age and sex.</div></div><div><h3>Results</h3><div>Among the 103,785 matched pairs, OSA patients had significantly higher odds of depressive disorders [adjusted OR = 1.62 (95 % CI: 1.60–1.63)] and anxiety disorders [adjusted OR = 1.56 (95 % CI: 1.54–1.58)] compared to controls. Females with OSA were particularly susceptible to these psychiatric conditions. The risk of psychiatric disorders in OSA patients increased with age, peaking for depression between 60 and 79 years and for anxiety between 40 and 59 years, before slightly declining in the oldest cohort.</div></div><div><h3>Conclusion</h3><div>OSA is significantly associated with an increased risk of depressive and anxiety disorders, with pronounced vulnerabilities observed among females and specific age groups. These findings underscore the need for age- and sex-specific considerations in managing OSA and its psychiatric comorbidities, emphasizing a more individualized approach to treatment to enhance patient outcomes.</div></div>","PeriodicalId":50074,"journal":{"name":"Journal of Psychosomatic Research","volume":"190 ","pages":"Article 112064"},"PeriodicalIF":3.5,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143429637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}