Journal of Veterinary Medical Science最新文献_第7页

Distribution of lesions in psittacine birds naturally infected with parrot bornavirus in Japan. 日本自然感染鹦鹉病毒的鹦鹉鸟的病变分布。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-11-01 Epub Date: 2024-09-27 DOI: 10.1292/jvms.24-0061

Chinatsu Fujiwara, Naoyuki Aihara, Motokazu Yoshino, Takanori Shiga, Kan Fujino, Ryo Komorizono, Akiko Makino, Keizo Tomonaga, Reiko Soga, Junichi Kamiie

{"title":"Distribution of lesions in psittacine birds naturally infected with parrot bornavirus in Japan.","authors":"Chinatsu Fujiwara, Naoyuki Aihara, Motokazu Yoshino, Takanori Shiga, Kan Fujino, Ryo Komorizono, Akiko Makino, Keizo Tomonaga, Reiko Soga, Junichi Kamiie","doi":"10.1292/jvms.24-0061","DOIUrl":"10.1292/jvms.24-0061","url":null,"abstract":"Mononuclear cell infiltration of the central nervous system and ganglioneuritis are characteristic histopathological findings of proventricular dilatation disease (PDD) caused by parrot bornavirus (PaBV) infection. The purpose of this study was to clarify the link between the degree of inflammatory lesions and the distribution of the virus antigen in naturally PaBV-infected parrots. Pathological examination was performed on 18 PaBV-infected birds identified by reverse transcriptase-PCR. Dilatation of the crop, proventriculus, and ventriculus was observed in all 18 (100%) birds, and dilation of the right ventricle of the heart was observed in 14/18 (78%) birds. Cases were classified based on the scores for the distribution and degree of histological lesions into neural type, with severe brain lesions, digestive type, with severe gastric lesions, or nervous/digestive type, with severe lesions in both the brain and ventriculus. The PaBV immunohistological score correlated with the inflammatory lesion scores. Ganglioneuritis, myocarditis, and myocardial degeneration were frequently observed in the heart. Interestingly, macroscopic and microscopic lesions and virus antigen were detected in the hearts of all three histological types. The present study showed that parrots naturally infected with PaBVs can be grouped into three types based on the lesion distribution, and heart failure is an important symptom in PaBV-infected parrots.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"1110-1118"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of urachal abscess resection via colpotomy in a cow. 一例通过结肠切除术切除尿道脓肿的奶牛。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-11-01 Epub Date: 2024-09-17 DOI: 10.1292/jvms.24-0256

Reiichiro Sato, Yukiko Sato, Naoyuki Fuke, Ryoko Uemura, Adrian Steiner

引用次数: 0

A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells. 针对肉豆蔻酰化富丙氨酸 C 激酶底物 N 末端的多肽可促进 SH-SY5Y 人神经母细胞瘤细胞的神经元分化。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-11-01 Epub Date: 2024-09-27 DOI: 10.1292/jvms.24-0276

Jannatul Ferdous, Kiyotada Naitou, Mitsuya Shiraishi

{"title":"A peptide against the N-terminus of myristoylated alanine-rich C kinase substrate promotes neuronal differentiation in SH-SY5Y human neuroblastoma cells.","authors":"Jannatul Ferdous, Kiyotada Naitou, Mitsuya Shiraishi","doi":"10.1292/jvms.24-0276","DOIUrl":"10.1292/jvms.24-0276","url":null,"abstract":"Myristoylated alanine-rich protein kinase C substrate (MARCKS) plays crucial roles in neuronal functions and differentiation. However, specific effects of the myristoylated N-terminal sequence (MANS) peptide, a widely used MARCKS modulator comprising the initial 24 amino acids of MARCKS, on neuronal cells remain unclear. Therefore, in this study, we aimed to examine the effects and action mechanisms of the MANS peptide on SH-SY5Y human neuroblastoma cells, which served as the in vitro neuronal cell models. MANS treatment of SH-SY5Y cells resulted in significant neurite outgrowth within 24 hr, which was as prominent as that induced by seven days of treatment with all-trans retinoic acid, the most common agent used to induce SH-SY5Y cell differentiation. Levels of synaptophysin, a neuronal marker protein, were significantly increased in the MANS peptide-treated cells. Additionally, increased MARCKS levels and decreased MARCKS phosphorylation were observed in MANS peptide-treated cells. Notably, neurite outgrowth induced by the MANS peptide was significantly reduced in MARCKS-knocked-down cells. Overall, these results suggest the MANS peptide as a novel agent for SH-SY5Y cell differentiation, particularly for the analysis of MARCKS functions.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"1136-1144"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The anti-inflammatory effects of Fuzapladib in an endotoxemic porcine model. 福扎普拉迪布在猪内毒素模型中的抗炎作用

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-11-01 Epub Date: 2024-09-12 DOI: 10.1292/jvms.24-0190

Chihiro Sugita, Takaharu Itami, Taku Miyasho, I-Ying Chen, Taku Hirokawa, Haruki Tsukui, Miki Kato, Marin Shibuya, Yuto Sano, Keiko Kato, Kazuto Yamashita

{"title":"The anti-inflammatory effects of Fuzapladib in an endotoxemic porcine model.","authors":"Chihiro Sugita, Takaharu Itami, Taku Miyasho, I-Ying Chen, Taku Hirokawa, Haruki Tsukui, Miki Kato, Marin Shibuya, Yuto Sano, Keiko Kato, Kazuto Yamashita","doi":"10.1292/jvms.24-0190","DOIUrl":"10.1292/jvms.24-0190","url":null,"abstract":"Endotoxemia is a systemic inflammatory condition caused by lipopolysaccharide (LPS) stimulation, which produces inflammatory cytokines. Fuzapladib (FZP) inhibits the activation of adhesion molecules found on the surface of inflammatory cells, mitigating inflammation. In this study, we evaluated the therapeutic effects of fuzapladib on inflammatory cytokines and cardio-respiratory function using an LPS-induced endotoxemic porcine model. Fifteen pigs were separated into three groups: low-FZP (n=5), high-FZP (n=5), and control (n=5). Pigs were administered LPS under general anesthesia, and complete blood cell count, blood biochemistry, inflammatory cytokines, and cardio-respiratory function were evaluated. Statistical analysis was performed using a linear mixed-effects model and the Steel-Dwass test, with a significance threshold of P<0.05. During the 4 hr experimental period, one pig in the control group and two pigs in the low-FZP group died due to hypoxemia and hypotension. In the early acute changes following LPS administration, the high-FZP group maintained significantly higher arterial oxygen partial pressure and normal blood pressure compared to the control group. Although interleukin-6 levels increased in all groups during the experiment, they were significantly lower in the high-FZP group compared to the control group. Other parameters showed no clinically significant differences. In conclusion, while high-dose fuzapladib did not reduce organ damage in the porcine endotoxemia model, it suppressed interleukin-6 production, delayed the progression of deterioration, and contributed to a reduction in mortality during the observation period.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"1145-1155"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of DNase I in DNA degradation and cell-free DNA generation after acetaminophen-induced hepatic injury. DNase I 在对乙酰氨基酚引起的肝损伤后 DNA 降解和游离 DNA 生成中的作用

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-11-01 Epub Date: 2024-09-18 DOI: 10.1292/jvms.23-0344

Shuhei Takada, Shuhei Ogawa, Ryushin Mizuta

引用次数: 0

Investigating drug residues in Mongolian milk using a newly developed method with high performance liquid chromatography and a photo diode array. 利用新开发的高效液相色谱法和光电二极管阵列调查蒙古牛奶中的药物残留。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-10-14 DOI: 10.1292/jvms.24-0113

Delgermurun Dugar, Kodai Motohira, Nyamsuren Purevdorj, Bolormaa Pelden, Shouta Mm Nakayama, Mayumi Ishizuka, Yoshinori Ikenaka

{"title":"Investigating drug residues in Mongolian milk using a newly developed method with high performance liquid chromatography and a photo diode array.","authors":"Delgermurun Dugar, Kodai Motohira, Nyamsuren Purevdorj, Bolormaa Pelden, Shouta Mm Nakayama, Mayumi Ishizuka, Yoshinori Ikenaka","doi":"10.1292/jvms.24-0113","DOIUrl":"https://doi.org/10.1292/jvms.24-0113","url":null,"abstract":"Despite the beneficial impacts of using drugs in animal husbandry, the risks of drug residues in animal products are a concern worldwide. Therefore, most countries have developed systems and methods to detect and monitor drug residues in animal products using high performance liquid chromatography (HPLC) with mass spectrometry (MS). However, MS detectors are not available in all universities; thus, we developed a new method suitable for ultraviolet detection. We first validated a new method targeting tetracycline and albendazole in milk and evaluated these drug residues in 50 samples collected from farms and supermarkets in Mongolia. The practical limit of quantification (PQL) calculated in our newly developed method was suitable to detect the maximum residual limits defined in Codex Alimentarius, and the accuracy and precision of a new method were comparable to previous studies. In particular, inter-day analysis showed great precision, with albendazole showing a 99% recovery rate with ± 3.3 of relative standard deviation (RSD). In addition, we evaluated our drugs contamination, but targeted drugs residues were not detected in the current sample set. However, this may reflect the decreased use of tetracycline in the veterinary field and seasonal use of albendazole in Mongolia. Therefore, these drugs must be continuously monitored. To the best of our knowledge, this is the first report about drug residues in milk published in an international journal by a Mongolian domestic institution. Further investigations of drug residue in Mongolia are urgently needed.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transvenous embolization of patent ductus arteriosus in 16 dogs using the Amplatzer Vascular Plug II device: description of a modified technique and complications. 使用 Amplatzer Vascular Plug II 装置对 16 只狗的动脉导管未闭进行经静脉栓塞治疗：改良技术及并发症描述。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-10-01 Epub Date: 2024-09-02 DOI: 10.1292/jvms.23-0445

Antoine Dubès, Jean-Benoît Thambo, Virginie Loyer, Pierre Menaut

{"title":"Transvenous embolization of patent ductus arteriosus in 16 dogs using the Amplatzer Vascular Plug II device: description of a modified technique and complications.","authors":"Antoine Dubès, Jean-Benoît Thambo, Virginie Loyer, Pierre Menaut","doi":"10.1292/jvms.23-0445","DOIUrl":"10.1292/jvms.23-0445","url":null,"abstract":"Patent ductus arteriosus (PDA) is a deadly congenital disease in dogs if left untreated. Occlusion of the defect is the treatment of choice and can be achieved by surgical ligation or interventional closure. In this retrospective study of 16 dogs, an alternative to the classically used canine device which is placed by an arterial route is described. The Amplatzer Vascular Plug II® (AVPII) can be deployed by a transvenous approach, using a modified and simplified technique using a single catheter to perform angiography and device delivery. This allows the percutaneous treatment of smaller dogs <3 kg and the concomitant treatment of pulmonic stenosis if present. Successful and complete closure was achieved in all dogs with a mean device/ampulla diameter ratio of 1.28 and a mean device/ostium ratio of 3.6. Embolization into the pulmonary artery was observed in one dog where the device/ampulla diameter ratio was <1.1 and device/ostium ratio was <2.1. In conclusion, our study confirms that PDA transvenous closure using the AVPII appears to be a viable alternative to transarterial closure, allowing the treatment of smaller dogs and a fully percutaneous approach. Care should be taken in patients with very large ducti where undersizing might result in device embolization.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"1089-1095"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11442394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the mutations in the genes involved in Janus kinase/signal transducer and activator of transcription pathway in canine large cell gastrointestinal lymphoma. 犬大细胞胃肠道淋巴瘤中 Janus 激酶/信号转导和转录激活通路相关基因突变的研究。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-10-01 Epub Date: 2024-08-13 DOI: 10.1292/jvms.24-0096

Takumi Tsuruta, Naoki Matsumura, Keijiro Mizukami, Yuko Goto-Koshino, Tomomi Aoi, Ryoko Yamada, Itsuma Nagao, Megumi Sakamoto, Taisuke Nakagawa, Ray Fukuoka, Aki Ohmi, James K Chambers, Kazuyuki Uchida, Yukihide Momozawa, Hirotaka Tomiyasu

{"title":"Investigation of the mutations in the genes involved in Janus kinase/signal transducer and activator of transcription pathway in canine large cell gastrointestinal lymphoma.","authors":"Takumi Tsuruta, Naoki Matsumura, Keijiro Mizukami, Yuko Goto-Koshino, Tomomi Aoi, Ryoko Yamada, Itsuma Nagao, Megumi Sakamoto, Taisuke Nakagawa, Ray Fukuoka, Aki Ohmi, James K Chambers, Kazuyuki Uchida, Yukihide Momozawa, Hirotaka Tomiyasu","doi":"10.1292/jvms.24-0096","DOIUrl":"10.1292/jvms.24-0096","url":null,"abstract":"Canine gastrointestinal lymphoma is known to be of T-cell origin in most cases, but the molecular biological aberrations have not been clarified. In human intestinal T-cell lymphoma, the mutations in the genes associated with Janus kinase/signal transducer and activator of transcription (JAK-STAT) pathway have been frequently observed. In this study, the gene mutations were investigated in 31 dogs with large cell gastrointestinal lymphoma (LCGIL) by focusing on the genes involved in JAK-STAT pathway. Next-generation sequencing analysis to examine the mutations in STAT3, STAT5B, and JAK1 genes throughout the exon regions revealed the mutations in STAT3 gene in two dogs and JAK1 gene in one dog. In conclusion, this study could not indicate the associations of gene mutations in JAK-STAT pathway with LCGIL in most canine cases.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"1052-1055"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11442398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aquaporin 3 is expressed in the basaloid cells of canine sebaceous glands. Aquaporin 3 在犬皮脂腺的基底细胞中表达。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-10-01 Epub Date: 2024-08-15 DOI: 10.1292/jvms.24-0188

Hiroko Sonoda, Yoshiki Taniguchi, Naruki Fujimoto, Yoshiki Higashijima, Toshiyuki Matsuzaki, Takuya Hirai, Teruo Itoh, Kazuyuki Uchida, Masahiro Ikeda

引用次数: 0

A probable cluster of premature birth and stillbirth caused by Leptospira interrogans serogroup Hebdomadis in an integrated swine farm in Nagasaki Prefecture, Japan. 日本长崎县一家综合养猪场可能发生由钩端螺旋体血清群 Hebdomadis 引起的早产和死胎群。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-10-01 Epub Date: 2024-08-07 DOI: 10.1292/jvms.24-0215

Yoshimi Terayama, Masashi Maeda, Yusuke Hata, Youhei Kawasaki, Nobuo Koizumi

引用次数: 0