Journal of Veterinary Medical Science最新文献_第7页

Treatment of esophagogastric intussusception due to cryptosporidiosis using paromomycin in a corn snake (Pantherophis guttatus). 用帕罗霉素治疗隐孢子虫病引起的食管胃肠套叠。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-02-07 DOI: 10.1292/jvms.24-0483

Urarako Shimizu, Manabu Kurihara, Kenichi Tamukai, Kazutaka Yamada

引用次数: 0

Developmental process and homeostasis of whale long bones lacking medullary cavity using the radius of Antarctic minke whales, Balaenoptera bonaerensis. 以南极小须鲸（Balaenoptera bonaerensis）的桡骨为例，探讨缺乏髓腔的鲸鱼长骨的发育过程和稳态。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-02-13 DOI: 10.1292/jvms.24-0430

Yayoi Izu, Hajime Ishikawa, Satoshi Soeta

{"title":"Developmental process and homeostasis of whale long bones lacking medullary cavity using the radius of Antarctic minke whales, Balaenoptera bonaerensis.","authors":"Yayoi Izu, Hajime Ishikawa, Satoshi Soeta","doi":"10.1292/jvms.24-0430","DOIUrl":"10.1292/jvms.24-0430","url":null,"abstract":"Whales, Earth's largest mammals and live in water, form long bones without marrow cavities. Body size and mechanical stress impact the bone formation and homeostasis, yet the specific developmental processes remain unclear. Here, we demonstrate the histological changes in whale long bones from fetal to mature stages using the radius of Antarctic minke whales in comparison with domestic cats and cattle. Through intramembranous ossification and remodeling, long bones enlarge their diameters and marrow cavities, respectively. It has been demonstrated that relatively small animals, such as cats, develop the radially arranged \"primary osteonal bone,\" whereas larger animals, including cattle, form \"laminar bone\" initiated by the formation of circumferentially arranged hypercalcified lines during intramembranous ossification. Here, we demonstrated that whales form laminar bones, transitioning from circumferential in the fetus to radial during postnatal growth, and thereafter cortical bones become compact. After maturation, bone remodeling primarily occurs in the lateral and medial regions of long bones, while the bone layers in the cranial-caudal region never undergo complete resorption. As a result, these layers remain as a wire-netting structure composed of thin bone layers, without forming an open medullary cavity. These data suggest that whales enlarge their long bones through laminar bone formation and form long bones without a marrow cavity by regulating bone resorption areas during the developmental process and in maintaining homeostasis.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"336-348"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of the neonicotinoid pesticide clothianidin at a no-observed-adverse-effect-level (NOAEL) dose on maternal behavior in pregnant mice and their female offspring. 新烟碱类农药噻虫胺（NOAEL）对孕鼠及其雌性后代母性行为的影响。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-02-24 DOI: 10.1292/jvms.24-0372

Sarika Nunobiki, Ayano Yoshimoto, Makiko Ito, Sakura Yonoichi, Yukako Hara, Yuya Ishida, Rinako Morishita, Youhei Mantani, Toshifumi Yokoyama, Tetsushi Hirano, Yoshinori Ikenaka, Nobuhiko Hoshi

{"title":"Effect of the neonicotinoid pesticide clothianidin at a no-observed-adverse-effect-level (NOAEL) dose on maternal behavior in pregnant mice and their female offspring.","authors":"Sarika Nunobiki, Ayano Yoshimoto, Makiko Ito, Sakura Yonoichi, Yukako Hara, Yuya Ishida, Rinako Morishita, Youhei Mantani, Toshifumi Yokoyama, Tetsushi Hirano, Yoshinori Ikenaka, Nobuhiko Hoshi","doi":"10.1292/jvms.24-0372","DOIUrl":"10.1292/jvms.24-0372","url":null,"abstract":"Our previous reports showed that exposure to the neonicotinoid pesticide clothianidin (CLO) at a no-observed-adverse-effect-level (NOAEL) dose during fetal development and lactation in mice led to higher rates of maternal neglect and infanticide. Although the demonstrated association between decreased oxytocin secretion and decreased maternal parenting behavior implies a link to declining oxytocin levels, no evidence has yet emerged in CLO to clearly establish such an association. This study investigated the effects of CLO on maternal behavior and oxytocin in C57BL/6N mice exposed during pregnancy and lactation (F0 mothers) as well as in their adult female offspring (F1 mothers). The effects were assessed using nest building assays during pregnancy and pup retrieval assessment after delivery. The results showed a decrease in oxytocin secretion and a marked decrease in pup retrieval behavior among the F0 mothers in the CLO exposure group compared to those in the control group. Their offspring, the F1 mothers, showed significantly lower nest-building scores during pregnancy. In conclusion, this study is the first to examine the potential mechanisms by which CLO exposure in mothers at the NOAEL dose during pregnancy and lactation results in reduced plasma oxytocin levels, subsequently leading to a decline in maternal behaviors such as pup retrieval. Furthermore, these effects may impair maternal behaviors in the next generation, when the offspring mice become mothers.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"411-418"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Establishing tentative cut-off values for disk diffusion method for Pasteurella multocida and Mannheimia haemolytica from livestock animals in Japan. 建立日本家畜多杀性巴氏杆菌和溶血性曼海默病圆盘扩散法的初步临界值。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-02-17 DOI: 10.1292/jvms.24-0474

Mio Kumakawa, Ryoko Akama, Yuta Hosoi, Yukari Hiraoka, Saki Harada, Mari Matsuda, Michiko Kawanishi, Hideo Sekiguchi

{"title":"Establishing tentative cut-off values for disk diffusion method for Pasteurella multocida and Mannheimia haemolytica from livestock animals in Japan.","authors":"Mio Kumakawa, Ryoko Akama, Yuta Hosoi, Yukari Hiraoka, Saki Harada, Mari Matsuda, Michiko Kawanishi, Hideo Sekiguchi","doi":"10.1292/jvms.24-0474","DOIUrl":"10.1292/jvms.24-0474","url":null,"abstract":"Although the disk diffusion method is a useful and widely utilized antimicrobial susceptibility testing method in clinical veterinary practice, the available clinical breakpoints (CBPs) for the combination of bacterial species and antimicrobials are still limited. This study aimed to establish tentative cut-off values by analyzing the relationship between minimum inhibitory concentration and the inhibition zone diameter of the disk diffusion method for Pasteurella multocida and Mannheimia haemolytica, collected by the Japanese Veterinary Antimicrobial Resistance Monitoring system (JVARM), for the antimicrobial agents approved in Japan for the treatment of respiratory diseases in cattle and swine. Among the antimicrobial agents without CBPs for the disk diffusion method in the Clinical and Laboratory Standards Institute (CLSI), we were able to determine the tentative cut-off values of ampicillin (ABPC, S ≥25 mm, R ≤24 mm in swine), dihydrostreptomycin (DSM, S ≥8 mm in cattle, S ≥12 mm in swine), kanamycin (KM, S ≥16 mm in cattle, S ≥17 mm in swine), tetracycline (TC, S ≥21 mm, R ≤20 mm in cattle) and tiamulin (TML, S ≥13 mm in swine) for P. multocida, and CEZ (S ≥23 mm), DSM (S ≥10 mm), KM (S ≥18 mm) and TC (S ≥23 mm, R ≤20 mm) for M. haemolytica. These results should encourage the practical use of antimicrobial susceptibility testing in the clinical field and contribute to furthering prudent use of antimicrobial agents.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"349-355"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964866/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In vitro susceptibility of differentiated SH-SY5Y human neuroblastoma cells to herpes simplex virus type 1 and Japanese encephalitis virus infection. 分化的SH-SY5Y人神经母细胞瘤细胞对1型单纯疱疹病毒和乙型脑炎病毒感染的体外敏感性

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-02-24 DOI: 10.1292/jvms.24-0405

Jannatul Ferdous, Haruka Makino, Tatsunori Masatani, Yoshikazu Fujimoto, Kiyotada Naitou, Mitsuya Shiraishi

引用次数: 0

Transthoracic echocardiographic reference intervals in 214 adult Golden retrievers. 214只成年金毛猎犬的经胸超声心动图参考间隔。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-02-12 DOI: 10.1292/jvms.24-0268

Mara Bagardi, Paolo Ferrari, Chiara Locatelli, Sara Ghilardi, Francesca Zanchi, Tommaso Vezzosi, Francesco Porciello, Mark Rishniw, Paola G Brambilla

{"title":"Transthoracic echocardiographic reference intervals in 214 adult Golden retrievers.","authors":"Mara Bagardi, Paolo Ferrari, Chiara Locatelli, Sara Ghilardi, Francesca Zanchi, Tommaso Vezzosi, Francesco Porciello, Mark Rishniw, Paola G Brambilla","doi":"10.1292/jvms.24-0268","DOIUrl":"10.1292/jvms.24-0268","url":null,"abstract":"This study describes the echocardiographic reference intervals in a large sample of Golden retrievers from the database of the Italian Veterinary Observatory for Cardiac Diseases. The echocardiographic variables and the cardiac functionality indexes obtained from 2012 to 2022 in 214 (122 females, 92 males) healthy adult Golden retrievers were compared with the previously published data for this breed and with data from the general canine population and other breeds. The diastolic left ventricular internal diameter and the left ventricle's systolic and diastolic allometric indices were higher than those reported for the general canine population (P<0.05). The same was true for the left ventricular end-diastolic and end-systolic volumes measured by Simpson's method of discs (P<0.01). Fractional shortening of the left ventricle was lower (P=0.002) and aortic flow velocity was higher (P<0.001) than the value previously reported for Golden retrievers. The reference intervals obtained in this study are useful for clinical echocardiography and for echocardiographic screening programs in Golden retrievers.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"356-363"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of gelatin-epigallocatechin gallate nanoparticles with hyaluronic acid coating for treating dry eye associated keratopathy in rats. 透明质酸涂层明胶-表没食子儿茶素没食子酸盐纳米颗粒治疗大鼠干眼相关性角膜病变的疗效评价。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-02-18 DOI: 10.1292/jvms.24-0250

Man-Ha Chan, Ching-Li Tseng, Wei-Hsiang Huang, Chung-Tien Lin

{"title":"Assessment of gelatin-epigallocatechin gallate nanoparticles with hyaluronic acid coating for treating dry eye associated keratopathy in rats.","authors":"Man-Ha Chan, Ching-Li Tseng, Wei-Hsiang Huang, Chung-Tien Lin","doi":"10.1292/jvms.24-0250","DOIUrl":"10.1292/jvms.24-0250","url":null,"abstract":"Keratoconjunctivitis sicca (KCS) is a common ocular disease in dogs characterized by inflammation of the cornea and conjunctiva. This study investigates the effectiveness of gelatin-epigallocatechin gallate nanoparticles with hyaluronic acid coating (GEH NPs) and various artificial tears in treating KCS led keratopathy in a rat model. Eighteen female Sprague-Dawley rats, aged 6 to 8 weeks were randomly assigned to 6 groups of 3. All rats except the Sham group underwent unilateral exorbital and infraorbital lacrimal gland excisions to induce KCS. The treatment groups included a KCS group without treatment, a GEH group treated with GEH NPs, and 3 groups receiving different artificial tears. Clinical examinations, including slit-lamp biomicroscopy, optical coherence tomography (OCT), and ocular surface analyser-VET (OSA-VET) were conducted preoperatively at 1 and 2 weeks postoperatively. For treating KCS associated keratopathy, the GEH NPs showed superior outcomes and consistently ranked among the strongest treatment options in most aspects evaluated, including reduced corneal irregularity, improved tear film stability, and lower fluorescein scores, indicating better corneal integrity. Additionally, the GEH group displayed the least inflammatory cell infiltration and maintained a healthier epithelial structure, further underscoring its protective effects. GEH was administered twice daily while other treatment groups were administrated 3 times daily, highlighting its efficacy even with a lower dosing frequency. The artificial tears demonstrated variable benefits on KCS led keratopathy across different evaluations. GEH NPs exhibited excellent protective effects and therapeutic potential on dry eye associated keratopathy based on this study.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"364-376"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of immunogenicity of 17 Burkholderia mallei antigens and whole cell lysate using indirect ELISA. 间接ELISA法比较17种马尔氏伯克氏菌抗原与全细胞裂解液的免疫原性。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-03-04 DOI: 10.1292/jvms.25-0039

Yoshiki Ichikawa, Yukiko Iinuma, Tomohiro Okagawa, Ryo Shimbo, Batchuluun Enkhtuul, Ochirbat Khurtsbaatar, Yuta Kinoshita, Hidekazu Niwa, Keisuke Aoshima, Atsushi Kobayashi, Vanaabaatar Batbaatar, Kazuhiko Ohashi, Takashi Kimura

{"title":"Comparison of immunogenicity of 17 Burkholderia mallei antigens and whole cell lysate using indirect ELISA.","authors":"Yoshiki Ichikawa, Yukiko Iinuma, Tomohiro Okagawa, Ryo Shimbo, Batchuluun Enkhtuul, Ochirbat Khurtsbaatar, Yuta Kinoshita, Hidekazu Niwa, Keisuke Aoshima, Atsushi Kobayashi, Vanaabaatar Batbaatar, Kazuhiko Ohashi, Takashi Kimura","doi":"10.1292/jvms.25-0039","DOIUrl":"10.1292/jvms.25-0039","url":null,"abstract":"Glanders is a World Organization for Animal Health (WOAH)-notifiable equine disease caused by the infection of Burkholderia mallei, and is endemic in Mongolia, South Asia, Africa, and South America. While the complement fixation test (CFT) has been widely used for serodiagnosis of glanders and is considered a standard serological test, it has several limitations. These limitations include poor specificity, labor intensive techniques, variability in antigen and protocol. Consequently, indirect enzyme-linked immunosorbent assays (iELISAs) based on recombinant proteins have been developed as alternative serodiagnostic assays to address some of the challenges associated with the CFT. The accuracy of iELISA relies on the B. mallei proteins used as an antigen. Hence, to determine the best diagnostic candidate in iELISA, in terms of sensitivity and specificity, a comparison of 17 immunogenic B. mallei proteins and detergent-based whole cell lysate (WCL) was performed. According to the sensitivity and specificity on the sera from glanderous and non-glanderous Mongolian native horses, iELISA using Hcp1, GroEL, and detergent-based WCL represented the highest diagnostic accuracy. These three candidates did not have cross-reactivity to horse sera with several other equine diseases. WCL, Hcp1, and GroEL showed considerable potential as antigens for iELISA in the serodiagnosis of glanders in Mongolia. Detergent-based WCL extraction offers a consistent approach for the preparation of reliable B. mallei antigen. WCL-iELISA should be further validated in a large-scale study to meet WOAH demands.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"394-401"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964862/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An increase in the urinary levels of prostaglandin D₂ and platelet-activating factor metabolites in dogs with mast cell tumor. 肥大细胞瘤犬尿中前列腺素D2和血小板活化因子代谢物水平的升高。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-02-21 DOI: 10.1292/jvms.24-0525

Arisa Yamazaki, Akane Hayashi, Tatsuro Nakamura, Yuta Hamasaki, Rikako Inoue, Sho Yoshimoto, Koji Kobayashi, Takayuki Nakagawa, Takahisa Murata

引用次数: 0

Phyllodes tumor in the mammary gland of a northern tree shrew (Tupaia belangeri). 北方树鼩乳腺的叶状瘤。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2025-04-01 Epub Date: 2025-02-17 DOI: 10.1292/jvms.24-0444

Tatsuro Hifumi, Yuki Tanaka, Kyoko Tsukiyama-Kohara, Noriaki Miyoshi

引用次数: 0