Journal of Veterinary Medical Science最新文献

Peripheral pulmonary arterial stenosis due to lung tumor in a cat. 猫肺肿瘤所致肺动脉外周狭窄。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-16 DOI: 10.1292/jvms.26-0383

Tomoya Morita, Shunto Miyashita, Ryo Miyamoto, Reina Fujiwara

引用次数: 0

Serological and molecular detection of pathogenic Leptospira in shelter dogs in Okayama and Yamaguchi Prefectures, Japan. 日本冈山县和山口县收容犬致病性钩端螺旋体血清学和分子检测。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-16 DOI: 10.1292/jvms.26-0418

Kazuki Kiuno, Nana Ushine, Nobuo Koizumi, Hiroshi Shimoda, Takashi Shimizu, Daisuke Hayasaka

引用次数: 0

Maternal immunity to fowl adenovirus in chicks derived from vaccinated hens. 雏鸡对家禽腺病毒的母体免疫来源于接种疫苗的母鸡。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-13 DOI: 10.1292/jvms.26-0445

Tatsuya Izutsu, Hiroki Otomo, Yoshihiro Shimoji, Eiji Oishi

{"title":"Maternal immunity to fowl adenovirus in chicks derived from vaccinated hens.","authors":"Tatsuya Izutsu, Hiroki Otomo, Yoshihiro Shimoji, Eiji Oishi","doi":"10.1292/jvms.26-0445","DOIUrl":"https://doi.org/10.1292/jvms.26-0445","url":null,"abstract":"Fowl adenoviruses (FAdVs) cause various diseases, including gizzard erosion, hepatitis-hydropericardium syndrome, and inclusion body hepatitis, resulting in significant economic losses in the poultry industry. In this study, as a preliminary step toward the development of a trivalent inactivated FAdV vaccine against serotypes 1, 2, and 8b, protective maternal antibody titers in chicks and maternal antibody transfer efficiency following vaccination of hens were investigated. In challenge trials using virulent FAdV-1/2/8b strains, chicks with maternal antibody titers <1:8 showed mortality rates ranging from 21% to 51%, whereas chicks with maternal antibody titers of 1:8 were protected from mortality, although some birds exhibited clinical signs of FAdV-associated disease. In contrast, chicks with maternal antibody titers of ≥1:16 showed no clinical signs or gross pathological lesions. Analysis of chick antibody titers derived from vaccinated hens with various antibody levels demonstrated that maternal antibody transfer rates against each viral serotype ranged from 25% to 40%, indicating that vaccinated hens require antibody titers of at least 1:64 to confer protective maternal antibody titers of 1:16 in chicks. In a study evaluating immunity onset using a trivalent FAdV-1/2/8b prototype inactivated vaccine, at least 90% of vaccinated hens showed antibody titers of ≥1:64 against each serotype by 21 days after vaccination, and all hens reached this titer by day 28. In a separate duration-of-immunity study, 100% of vaccinated hens maintained antibody titers of ≥1:64 against all serotypes for at least 15 months after vaccination.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effects of low-dose medetomidine and butorphanol premedication on anesthetic induction and recovery for intramuscular alfaxalone anesthesia in cats. 小剂量美托咪定和布托啡诺预用药对猫肌注阿法索龙麻醉诱导和恢复的影响。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-13 DOI: 10.1292/jvms.26-0321

Kakeru Tanaka, Haruka Shinozaki, Jun Tamura, Norihiko Oyama, Tadashi Sano, Akifumi Itoh, Takaharu Itami, Kazuto Yamashita

{"title":"The effects of low-dose medetomidine and butorphanol premedication on anesthetic induction and recovery for intramuscular alfaxalone anesthesia in cats.","authors":"Kakeru Tanaka, Haruka Shinozaki, Jun Tamura, Norihiko Oyama, Tadashi Sano, Akifumi Itoh, Takaharu Itami, Kazuto Yamashita","doi":"10.1292/jvms.26-0321","DOIUrl":"https://doi.org/10.1292/jvms.26-0321","url":null,"abstract":"This study evaluated effects of premedication with low-dose medetomidine (MED), butorphanol (BTR), or their combination on intramuscular (IM) alfaxalone (ALFX) anesthesia in cats. Five healthy purpose-bred cats were used in a completely randomized crossover study with a minimum 1-week washout period. Cats received three types of premedication: MED (5 µg/kg), BTR (0.3 mg/kg) or their combination via IM injection. After 15 min, anesthesia was induced with low (1.0 mg/kg), medium (2.5 mg/kg) or high (5.0 mg/kg) doses of IM ALFX. Anesthetic depth, tracheal intubation scores, and cardiorespiratory variables were evaluated over 120 min. Dose-dependent anesthetic effects of ALFX were observed across all protocols. Although tracheal intubation was difficult with MED alone, premedication with BTR alone or in combination with MED facilitated successful intubation. Notably, the MED-BTR combination resulted in a significantly greater sedation/anesthetic effect, even with lower doses of ALFX. The MED-BTR combination completely prevented MED-induced emesis. Cardiorespiratory evaluation revealed a decrease in heart rate with MED and MED-BTR premedication, and percutaneous arterial oxygen saturation dropped below 93% temporarily at higher ALFX doses. In summary, premedication combining BTR and low-dose MED facilitates reliable and smooth anesthetic induction with low-dose ALFX (1.0 mg/kg), achieving sufficient anesthetic depth without inducing prolonged or turbulent recovery. However, careful monitoring for bradycardia and hypoxemia is recommended, and its clinical application should be limited to young and healthy cats with sufficient cardiorespiratory reserve.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149172094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Examination of the expression of G-protein-coupled receptor (GPR) 37 across whole-body organs using GPR37-deficient mice by Western blotting. 免疫印迹法检测g蛋白偶联受体（GPR） 37缺陷小鼠全身器官表达

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-09 DOI: 10.1292/jvms.26-0233

Kai Kitamura, Ryusuke Nakajima, Shingo Miyawaki, Shouichiro Saito

{"title":"Examination of the expression of G-protein-coupled receptor (GPR) 37 across whole-body organs using GPR37-deficient mice by Western blotting.","authors":"Kai Kitamura, Ryusuke Nakajima, Shingo Miyawaki, Shouichiro Saito","doi":"10.1292/jvms.26-0233","DOIUrl":"https://doi.org/10.1292/jvms.26-0233","url":null,"abstract":"G-protein-coupled receptor (GPR) 37 is a G-protein-coupled receptor implicated in diverse physiological and pathological processes, including myelination and Parkinson's disease. Although its expression has been reported in the central nervous system (CNS), testis, and immune cells, the distribution of GPR37 at the protein level in peripheral tissues has remained unclear, partly because it is technically difficult to detect GPR37 specifically, which shares highly similar domains with other G protein-coupled receptors. In this study, to survey the protein expression of GPR37 in the major organs, we generated GPR37‑deficient mice by deleting the exon 1 start‑codon region using CRISPR/Cas9, and the protein expression of GPR37 in the major organs was compared between wild-type and GPR37‑deficient mice by western blotting. We confirmed GPR37 expression in the CNS and testis and newly demonstrated its protein‑level expression in the eye and inner ear, the latter representing a previously unreported organ in mammals. Across tissues, the 40 kDa short form of GPR37 was the predominant variant, whereas the 75 kDa form was restricted to the eye, revealing tissue‑specific differences in molecular forms. These findings provide reliable evidence for the tissue distribution of GPR37 and establish a robust framework for validating GPCR expression in vivo, offering new insights into its potential roles in neural, reproductive, and sensory systems.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149168308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A simple oral endotracheal intubation technique in rats using a modified 5-Fr vascular sheath and a commercially available ear-pick endoscope. 使用改良的5-Fr血管鞘和市售耳锥内窥镜对大鼠进行简单的口腔气管插管技术。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-08 DOI: 10.1292/jvms.26-0344

Toru Yoshiura, Satoko Kawauchi, Mizuki Hishinuma, Terushige Toyooka

引用次数: 0

Effects of environmental enrichment on outcomes of in vitro fertilization-embryo transfer in ICR mice. 环境富集对ICR小鼠体外受精-胚胎移植结果的影响。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-08 DOI: 10.1292/jvms.26-0263

Himeka Hayashi, Chiho Tsuchiya, Kotaro Unno, Hideaki Hayashi, Hiroshi Kitamura

引用次数: 0

A case of concurrent infection with bovine viral diarrhea virus and Salmonella enterica Serovar Typhimurium and its monophasic variant in a beef calf rearing farm. 牛病毒性腹泻病毒与肠炎沙门氏菌血清型鼠伤寒沙门氏菌及其单相变异同时感染一例。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-08 DOI: 10.1292/jvms.26-0287

Kenta Yamasaki, Katsuki Tanaka, Shoya Takaki, Akiko Uematsu, Michiko Kodani, Ken Iwao, Yoichi Inoue, Naoki Yamamoto, Akira Goto, Keiichi Hisaeda, Yasunori Shinozuka, Yosuke Sasaki, Makoto Nagai, Siro Endo, Tsuneyuki Masuda

{"title":"A case of concurrent infection with bovine viral diarrhea virus and Salmonella enterica Serovar Typhimurium and its monophasic variant in a beef calf rearing farm.","authors":"Kenta Yamasaki, Katsuki Tanaka, Shoya Takaki, Akiko Uematsu, Michiko Kodani, Ken Iwao, Yoichi Inoue, Naoki Yamamoto, Akira Goto, Keiichi Hisaeda, Yasunori Shinozuka, Yosuke Sasaki, Makoto Nagai, Siro Endo, Tsuneyuki Masuda","doi":"10.1292/jvms.26-0287","DOIUrl":"https://doi.org/10.1292/jvms.26-0287","url":null,"abstract":"In July 2022, an outbreak characterized by fever, diarrhea, and mortality occurred among suckling calves at a beef calf-rearing farm in Tottori Prefecture in Japan. A monophasic variant of Salmonella enterica serovar Typhimurium (Salmonella 4,[5],12:i:-) was subsequently isolated from a deceased calf. In August 2022, a persistently infected (PI) calf with bovine viral diarrhea virus (BVDV) was identified and subsequently euthanized. Between June and September 2022, the median number of treatments administered per month per calf in the calf-hutch area tended to be higher (P<0.20) and the mortality rate was significantly higher (P<0.05) compared with the same period in 2021. In this outbreak, the PI calf introduced to the farm likely transmitted BVDV to other suckling calves; the resulting immunosuppression may have exacerbated the clinical manifestations of concomitant Salmonella 4,[5],12:i:- infection, leading to substantial production losses on the farm. To our knowledge, this is the first report of a herd-level concurrent infection with BVDV and Salmonella 4,[5],12:i:- in Japan.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149129072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nasal fibroma associated with bovine papillomavirus-2 in a Japanese Black steer. 日本黑牛鼻纤维瘤与牛乳头瘤病毒-2相关。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-06 DOI: 10.1292/jvms.26-0333

Naoya Gakumazawa, Tomoya Tamura, Shoko Takeuchi, Haruhi Shono, Yusuke Goto, Yoshihiro Kumagai, Hayate Nishiura, Tomoyuki Shibahara

引用次数: 0

A retrospective study of 143 cases of ventricular septal defects in cattle aged under 12 months. 对143例12月龄以下牛室间隔缺损的回顾性研究。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2026-10-06 DOI: 10.1292/jvms.26-0380

Hisashi Inokuma, Masaki Maezawa, Megumi Itoh, Ena Chiba, Yoshiyuki Tsuchiya, Kio Yoshida, Ken-Ichi Watanabe, Manabu Yamada, Yoshiyasu Kobayashi, Hitoshi Hatai, James K Chambers, Kazuyuki Uchida

{"title":"A retrospective study of 143 cases of ventricular septal defects in cattle aged under 12 months.","authors":"Hisashi Inokuma, Masaki Maezawa, Megumi Itoh, Ena Chiba, Yoshiyuki Tsuchiya, Kio Yoshida, Ken-Ichi Watanabe, Manabu Yamada, Yoshiyasu Kobayashi, Hitoshi Hatai, James K Chambers, Kazuyuki Uchida","doi":"10.1292/jvms.26-0380","DOIUrl":"https://doi.org/10.1292/jvms.26-0380","url":null,"abstract":"To identify factors that influence the severity of clinical signs associated with ventricular septal defect (VSD) in calves, the clinical and pathological findings of 143 confirmed cases in animals under 12 months of age were retrospectively reviewed. Observed clinical signs included emaciation (92.3%), reduced vitality (83.9%), respiratory signs (77.6%), anorexia (74.1%), exercise intolerance (69.9%), cyanosis or pallor (50.3%), standing with assistance (32.9%), collapse (14.7%), death prior to euthanasia (11.9%), and signs of congestion (7.7%). Cardiac murmurs were detected in all cases and holosystolic murmurs in 86.0% of cases, while ejection murmurs, other systolic murmurs, and diastolic murmurs were detected in a small number of cases. The 143 cases were divided into two groups, the severe group (66 cases) and the mild group (77 cases), based on clinical scores, and their findings were compared. Statistically, there were no significant differences between the two groups in hematological parameters and the diameter of the septal defect. However, the blood urea nitrogen levels were significantly higher, and total cholesterol concentrations were significantly lower, in the severe group than in the mild group. In addition, the prevalence of concurrent malformations, including double outlet right ventricle, pulmonary stenosis, and patent ductus arteriosus, was significantly higher in the severe group than in the mild group. Although the defect diameter in the severe group (median: 2.0 cm) was larger than that in the mild group (median: 1.5 cm), the difference was marginal (P=0.0517).","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149129088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0