{"title":"Successful balloon angioplasty of right pulmonary coarctation with left pulmonary artery interruption in a cat: a long-term outcome follow-up case report.","authors":"Sunghoon Jeon, Gahyun Lee, Dahee Han, Jin-Kyung Kim, Namsoon Lee, Dongwoo Chang","doi":"10.1292/jvms.24-0501","DOIUrl":"https://doi.org/10.1292/jvms.24-0501","url":null,"abstract":"<p><p>A 4-month-old, British Shorthair kitten was referred to our institute for evaluation of a heart murmur. Thoracic radiography and echocardiography revealed narrowing of the right pulmonary artery, accompanied by right atrial dilation and right ventricular hypertrophy. The systolic flow velocity across the stenotic lesion was 6.15 m/sec, with a pressure gradient of 151.42 mmHg. Computed tomography confirmed right pulmonary coarctation with concurrent interruption of the left pulmonary artery. Balloon angioplasty was performed, reducing the systolic flow velocity from 6.15 m/sec to 2.79 m/sec and relieving right ventricular pressure overload. One year later, thoracic radiography revealed left lung collapse and right lung hyperinflation; however, the patient remained asymptomatic. At 33 months post-diagnosis, the patient continued to thrive without any clinical signs.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of anesthetic effects of medetomidine-midazolam-butorphanol and medetomidine-remimazolam-butorphanol administered subcutaneously and intraperitoneally in C57BL/6J mice.","authors":"Takeru Sasaki, Masaki Watanabe, Tomoki Omori, Ryosuke Nakanishi, Nobuya Sasaki","doi":"10.1292/jvms.25-0301","DOIUrl":"https://doi.org/10.1292/jvms.25-0301","url":null,"abstract":"<p><p>Anesthesia management in experimental animals is essential for animal welfare and data reproducibility. In Japan, medetomidine-midazolam-butorphanol (MMB) is commonly used due to ketamine restrictions. We developed medetomidine-remimazolam-butorphanol (MRB) by replacing midazolam with remimazolam for faster metabolism and recovery. This study compared MMB and MRB administered intraperitoneally (i.p.) or subcutaneously (s.c.) in C57BL/6J mice of both sexes. Induction and recovery were assessed using immobilization, loss of righting reflex, and return of righting reflex. MRB i.p. produced the fastest induction and recovery with relatively low variability, suggesting potential utility for brief procedures. In contrast, s.c. administration resulted in consistent onset and recovery profiles for both agents, which may be advantageous for routine experimental use.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aruto Takano, Chie Furuya, Daikichi Morinaga, April H Wardhana, Dyah H Sawitri, Toshimitsu Hatabu, Kazumi Sasai, Hiromitsu Katoh, Makoto Matsubayashi
{"title":"Evaluation of oocyst detection and PCR identification of chicken Eimeria species using intestinal contents of the rectum and cecum as different gastrointestinal tracts.","authors":"Aruto Takano, Chie Furuya, Daikichi Morinaga, April H Wardhana, Dyah H Sawitri, Toshimitsu Hatabu, Kazumi Sasai, Hiromitsu Katoh, Makoto Matsubayashi","doi":"10.1292/jvms.25-0252","DOIUrl":"https://doi.org/10.1292/jvms.25-0252","url":null,"abstract":"<p><p>In the present study, intestinal specimens were collected from layer chickens at poultry slaughterhouses and used to evaluate infection with Eimeria species. Intestinal contents were extracted separately from the rectum (from the duodenum to rectum) and cecum and used for analyses. Using flotation detection methods, the number of eimerian oocysts per gram was higher in the cecum than rectum. Polymerase chain reaction analysis also detected a greater abundance of Eimeria species in the cecum than the rectum. These results suggest that analysis of cecal contents could be more useful for detecting and identifying Eimeria species.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144709705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ai Koshikawa, Shingo Miki, Sangho Kim, Takashi Kimura, Keisuke Aoshima
{"title":"Calcinosis circumscripta of the extremities and the tongue with multifocal arterial calcification secondary to chronic kidney disease in a cat.","authors":"Ai Koshikawa, Shingo Miki, Sangho Kim, Takashi Kimura, Keisuke Aoshima","doi":"10.1292/jvms.25-0042","DOIUrl":"https://doi.org/10.1292/jvms.25-0042","url":null,"abstract":"<p><p>A 3-year-old neutered male mixed-breed cat was presented with right urinary tract obstruction caused by a urolith and severe atrophy of the left kidney. In the next year and a half, chronic kidney disease (CKD) progressed, and several masses were identified in the extremities, along with an ulcer on the tongue. Histologically, the extremity masses consisted of calcium deposits separated by fibrovascular septa, and the tongue ulcer showed severe neutrophilic infiltration with pervasive calcium deposition. These lesions were diagnosed as calcinosis circumscripta (CCs). Concurrently, multifocal mineralization of the aorta and of small- to medium-sized arteries in several organs indicated widespread vascular calcification. Both extremity and vascular lesions were likely secondary to the excessive calcium-phosphate product caused by CKD. Although CCs in either the extremities or tongue has been reported in cats, this case is notable for the presence of CCs in both extremities and tongue with systemic vascular calcification.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reduction in finisher pig death rate on a farm in Japan following use of a commercial killed vaccine against porcine reproductive and respiratory syndrome virus.","authors":"Yoriko Yonezawa, Tomohiro Nakagami, Nobuyuki Tsutsumi, Nozomu Momma, Osamu Taira, Ryota Matsuyama, Kohei Makita","doi":"10.1292/jvms.24-0506","DOIUrl":"https://doi.org/10.1292/jvms.24-0506","url":null,"abstract":"<p><p>PRRS (Porcine Reproductive and Respiratory Syndrome) is a costly disease in the global pig industry. In 2021, Nisseiken Co., Ltd. in Japan launched a PRRS-killed vaccine, PRRS-ME, but its effectiveness on reducing the death rate under field conditions remained unassessed. A longitudinal study on a PRRS-positive farm in Japan (July 2019-July 2022) evaluated its effect on death rates. Piglets on a PRRS-negative farrowing farm were vaccinated at 3 and 8 weeks of age in March 2021. The vaccinated piglets were introduced to the finisher farm, where a PRRS outbreak occurred. Vaccination coverage was not associated with the death rates of growers but was negatively associated with those of finishers. The predicted reduction in the death rate of finishers associated with complete vaccination coverage was 56.8%.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yukino Tamamura-Andoh, Sota Kobayashi, Itsuro Yamane, Mafumi Watanabe, Keerthi Siri Guruge, Ryuichi Uegaki, Nobuo Arai, Ayako Watanabe-Yanai, Taketoshi Iwata, Ken Katsuda, Masato Akiba, Masahiro Kusumoto
{"title":"Association between farm-level antimicrobial usage and antimicrobial resistance in Escherichia coli isolates from healthy swine in ten farms in Japan.","authors":"Yukino Tamamura-Andoh, Sota Kobayashi, Itsuro Yamane, Mafumi Watanabe, Keerthi Siri Guruge, Ryuichi Uegaki, Nobuo Arai, Ayako Watanabe-Yanai, Taketoshi Iwata, Ken Katsuda, Masato Akiba, Masahiro Kusumoto","doi":"10.1292/jvms.25-0221","DOIUrl":"https://doi.org/10.1292/jvms.25-0221","url":null,"abstract":"<p><p>We examined the antimicrobial resistance of 1,493 Escherichia coli isolates from 440 swine fecal samples (211 and 229 samples were obtained from the sow and fattening groups, respectively) on ten farms and analyzed the association between the antimicrobial resistance rate and the annual antimicrobial usage at the farm level adjusted by the daily defined dose in Japan. For most antimicrobial agents, the rate of resistance was greater on farms with higher levels of antimicrobial use, suggesting that the amount of the corresponding antimicrobial class used at the farm level may have affected the resistance rates. Some antimicrobial resistance was positively associated with the use of the corresponding or structurally related antimicrobial agents: resistance to tetracycline in the sow group and resistance to chloramphenicol, streptomycin, kanamycin, sulfonamide-trimethoprim, and nalidixic acid in the fattening group. In addition, for many antimicrobial-resistant strains, an association was found with the use of single or multiple antimicrobial classes other than the corresponding class: resistance to ampicillin and kanamycin in the sow group and resistance to ampicillin, cefazolin, cefoxitin, cefotaxime, tetracycline, chloramphenicol, streptomycin, kanamycin, gentamicin and nalidixic acid in the fattening group. In the case of the association with the noncorresponding class, most of the E. coli isolates were multidrug resistant, suggesting that there is a high possibility of coselection on farms and that reducing the use of multiple antimicrobial agents may be effective at decreasing antimicrobial resistance.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sang-Kwon Lee, Su-Min Baek, Jin-Kyu Park, Jinsu Kang, Min Jang, Kija Lee
{"title":"Pre-contrast hyperattenuating metastatic lymph node on computed tomography due to iodide accumulation in a dog with thyroid carcinoma.","authors":"Sang-Kwon Lee, Su-Min Baek, Jin-Kyu Park, Jinsu Kang, Min Jang, Kija Lee","doi":"10.1292/jvms.25-0198","DOIUrl":"https://doi.org/10.1292/jvms.25-0198","url":null,"abstract":"<p><p>An 11-year-old Bichon Frise presented with a right cervical mass. Computed tomography revealed a thyroid mass without significant lymphadenopathy; however, the caudal portion of the ipsilateral retropharyngeal lymph node exhibited marked hyperattenuation on pre-contrast images. Histopathology of this lymph node confirmed the presence of metastasis from thyroid adenocarcinoma. The caudal portion of the lymph node displayed dense tumor cells with abundant sodium/iodide symporter-positive cells. The observed hyperattenuation of the lymph node was presumed to result from iodide deposition associated with the metastasis of the thyroid tumor. This case suggests that even in the absence of lymph node enlargement, hyperattenuating lymph nodes should raise suspicion for metastasis in dogs with thyroid tumors. However, as this is a single case, further studies are needed to determine the broader applicability of this finding.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A review on ecological and physiological studies in bears from a One Health perspective.","authors":"Michito Shimozuru","doi":"10.1292/jvms.25-0215","DOIUrl":"https://doi.org/10.1292/jvms.25-0215","url":null,"abstract":"<p><p>The Hokkaido brown bear is the largest terrestrial mammal in the Hokkaido ecosystems and now inhabits almost all forests in Hokkaido, Japan. These bears have evolved through a unique shift from carnivorous to omnivorous feeding habits, which are of interest to their ecology. However, human-bear conflicts, such as human injury and crop or livestock damage, have become a serious concern, which requires ecological research for its mitigation. The hibernation behavior of bears has unique characteristics that differ from those of other small hibernators, including minimal decrease in body temperature. Interestingly, they show resistance to muscle atrophy and bone loss during prolonged periods of immobility. This review provides an overview of ecological and physiological studies on bears from One Health perspective, focusing on ecology, human-bear conflict, infectious diseases, and hibernating physiology and its application to human health.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paolo Martelli, Lee Foo Khong, Christopher Marriot Perkins, Jessica Pui Yin Li, Hok Lai Ho, Lell Luk
{"title":"First successful intra-uterine artificial insemination in a cownose ray (Rhinoptera javanica) using chilled semen.","authors":"Paolo Martelli, Lee Foo Khong, Christopher Marriot Perkins, Jessica Pui Yin Li, Hok Lai Ho, Lell Luk","doi":"10.1292/jvms.24-0293","DOIUrl":"https://doi.org/10.1292/jvms.24-0293","url":null,"abstract":"<p><p>Reproduction of endangered wildlife, including elasmobranchs, is a fundamental mission of modern aquariums. Captive breeding programs necessitate artificial insemination to better utilize the limited stock in each facility. A cownose ray (Rhinoptera javanica) was successfully inseminated producing a live offspring. The semen was collected under chemical restraint, extended with a custom-made solution and kept chilled at 6<sup>o</sup>C for 24 hr. The quality of the semen was assessed at collection and just prior to insemination, noting color, volume, subjective sperm motility, sperm viability and concentration. Intrauterine insemination was carried out under chemical restraint. The monitoring of pregnancy was performed by serial ultrasound scans of the fetus assessing gilling and heartbeat. A healthy female pup was born after a gestation of 429 days (61 weeks and 2 days). Genetic microsatellite analysis confirmed that the pup was not a product of parthenogenesis and identified the donor male as the sire. This is the first report of a successful artificial insemination in an aplacental viviparous ray, suggesting these techniques can be applied to other species in this clade.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Albert Chun-Chun Chuang, Thomas Chia-Tang Ho, Jacky Peng-Wen Chan
{"title":"Prostaglandin-induced luteolysis and estrous expression in dairy heifers: applications of ovulation prediction based on automated activity monitoring system.","authors":"Albert Chun-Chun Chuang, Thomas Chia-Tang Ho, Jacky Peng-Wen Chan","doi":"10.1292/jvms.25-0162","DOIUrl":"https://doi.org/10.1292/jvms.25-0162","url":null,"abstract":"<p><p>This study evaluated the effects of different prostaglandin F<sub>2α</sub> (PG) regimens on luteolysis, estrous behavior, and ovulation timing in dairy heifers using an automated activity monitoring (AAM) system. Eight days after presynchronized ovulation (designated as Day 0), twenty-seven heifers were assigned to one of three PG regimens, administered 24 hr apart: a single standard PG dose of 500 µg followed by saline (one standard dose, OSD, n=8), two low PG doses of 375 µg and 250 µg (two low doses, TLD-1.5, n=8), or two PG doses of 250 µg each (TLD-1, n=8). All heifers experienced complete luteolysis and ovulation after PG treatments, however, heifers in the TLD-1.5 and TLD-1 groups exhibited delayed progesterone (P<sub>4</sub>) decline, prolonged luteolysis, later estrus onset, and lower peak value of the estrous alarm (PA) than those in OSD. Despite these variations, the interval from estrus to ovulation remained stable, confirming AAM's reliability for predicting suitable artificial insemination (AI) timing. The delayed luteolytic patterns induced by each regimen affected estrous expressions, as the serum P<sub>4</sub> concentration on Day 1 was positively correlated to the timing of highest estradiol (E<sub>2</sub>) as well as ovulation but negatively correlated to PA. The ability of AAM to consistently predict ovulation, regardless of variations in luteolysis, ensures its practical value in AI programs. These findings highlighted the importance of optimizing PG regimens while reinforcing the role of AAM in reproductive management.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}