发布求助
文献互助 智能选刊 最新文献

Journal of Veterinary Medical Science最新文献

筛选
英文 中文
Characterization of senescent mesenchymal stem/stromal cells derived from equine bone marrow and the effects of NANOG on the senescent phenotypes. 从马骨髓中提取的衰老间充质干细胞/基质细胞的特征以及 NANOG 对衰老表型的影响。
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-09-01 Epub Date: 2024-07-08 DOI: 10.1292/jvms.24-0161
Chiho Kushida, Norihisa Tamura, Yoshinori Kasashima, Kota Sato, Katsuhiko Arai
{"title":"Characterization of senescent mesenchymal stem/stromal cells derived from equine bone marrow and the effects of NANOG on the senescent phenotypes.","authors":"Chiho Kushida, Norihisa Tamura, Yoshinori Kasashima, Kota Sato, Katsuhiko Arai","doi":"10.1292/jvms.24-0161","DOIUrl":"10.1292/jvms.24-0161","url":null,"abstract":"<p><p>In equine regenerative medicine using bone marrow-derived mesenchymal stem/stromal cells (BM-MSC), the importance of the quality management of BM-MSC has been widely recognized. However, there is little information concerning the relationship between cellular senescence and the stemness in equine BM-MSC. In this study, we showed that stemness markers (NANOG, OCT4, SOX2 and telomerase reverse transcriptase) and colony forming unit-fibroblast apparently decreased accompanied with incidence of senescence-associated β-galactosidase-positive cells by repeated passage. Additionally, we suggested that down-regulation of cell proliferation in senescent BM-MSC was related to increased expression of cyclin-dependent kinase inhibitor 2B (CDKN2B). On the other hand, forced expression of NANOG into senescent BM-MSC brought upregulation of several stemness markers and downregulation of CKDN2B accompanied with restoration of proliferation potential and osteogenic ability. These results suggested that expression of NANOG was important for the maintenance of the stemness in equine BM-MSC.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"930-937"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11422694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141555747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anti-tumor effect of proteasome inhibitor on canine urothelial carcinoma. 蛋白酶体抑制剂对犬尿道癌的抗肿瘤作用
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-09-01 Epub Date: 2024-07-19 DOI: 10.1292/jvms.23-0094
Yuka Kodera, Takaaki Iguchi, Daiki Kato, Namiko Ikeda, Masahiro Shinada, Susumu Aoki, Kyoka Soga, Toshio Li, Ryosuke Ohata, Shoma Koseki, Hayato Shibahara, Yosuke Takahashi, Yuko Hashimoto, Ryohei Nishimura, Takayuki Nakagawa
{"title":"Anti-tumor effect of proteasome inhibitor on canine urothelial carcinoma.","authors":"Yuka Kodera, Takaaki Iguchi, Daiki Kato, Namiko Ikeda, Masahiro Shinada, Susumu Aoki, Kyoka Soga, Toshio Li, Ryosuke Ohata, Shoma Koseki, Hayato Shibahara, Yosuke Takahashi, Yuko Hashimoto, Ryohei Nishimura, Takayuki Nakagawa","doi":"10.1292/jvms.23-0094","DOIUrl":"10.1292/jvms.23-0094","url":null,"abstract":"<p><p>Canine urothelial carcinoma (cUC) is one of the most malignant tumors affecting dogs; however, its proliferative mechanism is yet to be fully elucidated. The ubiquitin-proteasome system (UPS) is an important metabolic pathway regulating protein degradation, and its dysfunction leads to apoptosis. We investigated the antitumor effect of the proteasome inhibitor bortezomib, which blocks the UPS. Bortezomib inhibited cell growth in cUC cell lines by inducing apoptosis in vitro. These findings suggest the potential of bortezomib as a novel therapeutic drug for dogs with cUC.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"961-965"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11422692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three cases of paresis due to vertebral abscess in Shiba goats in Japan. 日本三例芝山羊因脊椎脓肿导致瘫痪的病例。
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-09-01 Epub Date: 2024-07-23 DOI: 10.1292/jvms.24-0158
Hisashi Inokuma, Kie Yamamoto, Reina Fujiwara, Masaki Maezawa, James K Chambers, Kazuyuki Uchida
{"title":"Three cases of paresis due to vertebral abscess in Shiba goats in Japan.","authors":"Hisashi Inokuma, Kie Yamamoto, Reina Fujiwara, Masaki Maezawa, James K Chambers, Kazuyuki Uchida","doi":"10.1292/jvms.24-0158","DOIUrl":"10.1292/jvms.24-0158","url":null,"abstract":"<p><p>Three Shiba goats aged 1 to 7 years kept in Ibaraki prefecture in Japan were presented with chief complaint of lumbar paralysis or gait abnormalities. As cerebrospinal setariasis were suspected in all cases at the first stage, ivermectin was administered to treat, but the response was insufficient. Necropsy revealed abscess formation on the ventral side of the spine at T5 in Case 1, T5-6 in Case 2, and C7-T1 in Case 3, causing compression of the spinal cord in all three cases. In addition to cerebrospinal setariasis, vertebral abscess should be considered as a cause of paresis or gait abnormalities in goats in Japan. Computed tomography was a useful for diagnosing vertebral abscess.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"946-950"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11422688/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141762165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular phylogenetical identification of bear roundworms (Baylisascaris transfuga) derived from wild Japanese black bears (Ursus thibetanus japonicus) around Lake Towada. 从十和田湖周围的野生日本黑熊（Ursus thibetanus japonicus）身上提取的熊蛔虫（Baylisascaris transfuga）的分子系统学鉴定。
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-09-01 Epub Date: 2024-07-16 DOI: 10.1292/jvms.24-0142
Kodai Kusakisako, Nanami Kaneda, Yuichi Kamiharako, Asako Haraguchi, Jun Hakozaki, Kazuhiko Nakayama, Hajar Hasan, Sakure Nakamura, Junji Shindo, Hiromi Ikadai
{"title":"Molecular phylogenetical identification of bear roundworms (Baylisascaris transfuga) derived from wild Japanese black bears (Ursus thibetanus japonicus) around Lake Towada.","authors":"Kodai Kusakisako, Nanami Kaneda, Yuichi Kamiharako, Asako Haraguchi, Jun Hakozaki, Kazuhiko Nakayama, Hajar Hasan, Sakure Nakamura, Junji Shindo, Hiromi Ikadai","doi":"10.1292/jvms.24-0142","DOIUrl":"10.1292/jvms.24-0142","url":null,"abstract":"<p><p>The bear roundworm Baylisascaris transfuga has been identified in several host bears (Ursinae). However, limited genetic information is available on the bear roundworm in Japanese populations. This study evaluated the genetic composition of bear roundworms isolated from wild Japanese black bears indigenous to Lake Towada, Japan. First, we conducted genetic and/or molecular phylogenetic analyses based on cytochrome c oxidase subunit II and internal transcribed spacer 2 among Baylisascaris species. These analyses revealed that the identified roundworms were genetically B. transfuga. In addition, the average body size of the obtained roundworms in this study was almost the same as that previously reported for B. transfuga. This study represents an important step in genetic research on the roundworm B. transfuga in Ursinae bears not only from Japan but also from the rest of the world.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"951-955"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11422683/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The first isolation of Clostridium massiliodielmoense from a dead beef cow in Japan and pitfalls to be aware of in identifying the Clostridium species. 从日本一头死亡肉牛中首次分离出 Massiliodielmoense 梭状芽孢杆菌，以及鉴别梭状芽孢杆菌种类时应注意的陷阱。
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-09-01 Epub Date: 2024-07-12 DOI: 10.1292/jvms.24-0086
Takashi Mada, Asami Umeda, Akira Kodama, Daisuke Takamatsu
{"title":"The first isolation of Clostridium massiliodielmoense from a dead beef cow in Japan and pitfalls to be aware of in identifying the Clostridium species.","authors":"Takashi Mada, Asami Umeda, Akira Kodama, Daisuke Takamatsu","doi":"10.1292/jvms.24-0086","DOIUrl":"10.1292/jvms.24-0086","url":null,"abstract":"<p><p>Clostridium sp. was detected in the organs of a cow with black watery diarrhea in Japan. Results identifying this species were inconsistent; Clostridium novyi type A infection was suggested by PCR assay targeting Clostridium fliC region (fliC-multiplex PCR), while 16S rRNA gene sequencing identified the isolated bacteria as Clostridium massiliodielmoense. Sequencing of fliC-multiplex PCR products from the isolates revealed the presence of fliC region in C. massiliodielmoense, which had 92.7% nucleotide similarity to that of C. novyi type A JCM 1406<sup>T</sup>, leading to the false positive detection of C. novyi by the PCR. This is the first C. massiliodielmoense isolation from clinical specimens, suggesting the need for further research on its pathogenicity and improvement in fliC-multiplex PCR.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"925-929"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11422693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between the left-right asymmetric motor-related conformation and the orientation of facial hair whorls in Japanese Kiso horses. 日本木曾马左右不对称的运动相关构型与面部毛发轮廓方向之间的关系。
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-09-01 Epub Date: 2024-07-09 DOI: 10.1292/jvms.24-0182
Sawa Onouchi, Tomoki Yoshida, Shouichiro Saito, Yasuro Atoji
{"title":"Relationship between the left-right asymmetric motor-related conformation and the orientation of facial hair whorls in Japanese Kiso horses.","authors":"Sawa Onouchi, Tomoki Yoshida, Shouichiro Saito, Yasuro Atoji","doi":"10.1292/jvms.24-0182","DOIUrl":"10.1292/jvms.24-0182","url":null,"abstract":"<p><p>We examined the relationship between inherited motor-related conformation and orientation of facial hair whorls in Japanese Kiso horses. Eleven horses were divided into clockwise, counterclockwise, and radial groups according to facial hair whorls. We placed six markers on anatomical landmarks of each lateral side in a horse and measured the height of the landmarks, the distance between adjacent landmarks, and the angle of the adjacent landmarks. In the counterclockwise group, the horses tended to exhibit higher values on the left side than on the right side, and the comparison of the height of landmarks revealed a significant difference between both sides. Therefore, the orientation of facial hair whorls may suggest the tendency of motor-related conformation, at least in counterclockwise group.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"920-924"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11422695/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Allergen-specific immunoglobulin-Es for dermatitis in the Japanese native Noma horses. 治疗日本本地野马皮炎的过敏原特异性免疫球蛋白-Es。
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-09-01 Epub Date: 2024-07-15 DOI: 10.1292/jvms.24-0107
Sae Yoshida, Akira Matsuda, Eri Iwata, Tetsushi Ono, Keiichi Hisaeda, Emi Ohzawa, Yasuharu Hiasa, Hitoshi Kitagawa
{"title":"Allergen-specific immunoglobulin-Es for dermatitis in the Japanese native Noma horses.","authors":"Sae Yoshida, Akira Matsuda, Eri Iwata, Tetsushi Ono, Keiichi Hisaeda, Emi Ohzawa, Yasuharu Hiasa, Hitoshi Kitagawa","doi":"10.1292/jvms.24-0107","DOIUrl":"10.1292/jvms.24-0107","url":null,"abstract":"<p><p>Noma horses are native Japanese horses. Health checkups revealed that many Noma horses developed dermatitis during summer, which subsided in winter. Seasonal development and signs of itching, suggestive of allergic dermatitis, were observed. In this study, allergen-specific IgE was measured using blood samples collected from 15 Noma horses in summer and winter to identify allergens highly associated with dermatitis. The presence of dermatitis in the subject individuals was recorded during blood sample collection. White blood cell and eosinophil counts, serum total IgE concentration, and serum allergen-specific IgE units (ARUs) were measured. White blood cell and eosinophil counts were significantly higher in horses with dermatitis in summer compared to winter. On the other hand, there was no significant difference in serum total IgE concentration regardless of the presence of dermatitis or the season. Horses with dermatitis in summer showed higher ARUs derived from red ants, horseflies, biting midges, cockroaches, deerflies, and mosquitoes than those in winter. These ARUs were positively correlated with white blood cell and eosinophil counts. The factor analysis results suggested that sensitization to some insects, such as mosquitoes and deerflies, may be a cause of dermatitis. In conclusion, insect-derived allergens could be associated with the onset of dermatitis in Noma horses.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"938-945"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11422699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic analysis based on next generation sequencing of Streptococcus equi subsp. equi isolated from horses imported into Japan. 基于新一代测序对从日本进口马匹中分离出的马链球菌亚种进行基因分析。
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-08-02 Epub Date: 2024-06-18 DOI: 10.1292/jvms.23-0342
Kei Nakajima, Kazufumi Kasuya, Hironobu Senba, Katsunori Tagami, Yuta Kinoshita, Hidekazu Niwa
{"title":"Genetic analysis based on next generation sequencing of Streptococcus equi subsp. equi isolated from horses imported into Japan.","authors":"Kei Nakajima, Kazufumi Kasuya, Hironobu Senba, Katsunori Tagami, Yuta Kinoshita, Hidekazu Niwa","doi":"10.1292/jvms.23-0342","DOIUrl":"10.1292/jvms.23-0342","url":null,"abstract":"<p><p>Strangles is a globally widespread, commonly diagnosed and important infectious disease of equids caused by Streptococcus equi subsp. equi. We performed whole genome sequencing of 19 S. equi isolates collected from imported horses at the Japanese border. Of these isolates, 15 isolates were obtained from clinical cases and 4 were from subclinical cases. The 19 isolates were grouped into 3 Bayesian analysis of population structure (BAPS) groups by the core genome single nucleotide polymorphism analysis corresponding to exporting country, SeM typing, or exporter of the horses. The 19 isolates possessed same pathogenic genes regardless of clinical status in imported horses and no antimicrobial resistance genes. The disease status of the horses may rather reflect the prior exposure of animals with sub-clinical infection to S. equi.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"828-832"},"PeriodicalIF":1.1,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11300130/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meningoencephalitis with malacia caused by Sarcocystis calchasi in a rock pigeon in Japan. 日本一只岩鸽患了由卡氏沙雷氏菌引起的脑膜脑炎并伴有畸形。
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-08-02 Epub Date: 2024-06-27 DOI: 10.1292/jvms.24-0069
Mio Kobayashi, Keisuke Takesue, Tetsuhito Kigata, Natsumi Kobayashi, Susumu Iwaide, Tomoaki Murakami, Hayato Harima, Akiko Yamazaki, Daigo Azakami, Makoto Shibutani, Toshinori Yoshida
{"title":"Meningoencephalitis with malacia caused by Sarcocystis calchasi in a rock pigeon in Japan.","authors":"Mio Kobayashi, Keisuke Takesue, Tetsuhito Kigata, Natsumi Kobayashi, Susumu Iwaide, Tomoaki Murakami, Hayato Harima, Akiko Yamazaki, Daigo Azakami, Makoto Shibutani, Toshinori Yoshida","doi":"10.1292/jvms.24-0069","DOIUrl":"10.1292/jvms.24-0069","url":null,"abstract":"<p><p>Sarcocystis spp. cause pigeon protozoan encephalitis, a neuronal disease. A female pigeon exhibiting torticollis had a necrotic area in the cerebral hemisphere surrounded by lesions with perivascular cuffing, gliosis, granulomatous foci, and meningitis. Non-necrotic lesions were also observed in the brainstem. Intact and degenerative schizonts were observed within the neuropils and neurons in the lesions. Deoxyribonucleic acid (DNA) was extracted from paraffin-embedded brain tissues and genetically analyzed after gel electrophoresis to determine Sarcocystis spp. using specific primer sets for 28S ribosomal ribonucleic acid and internal transcribed spacer region-1. DNA sequencing confirmed a significant homology with S. calchasi. This is the first report of meningoencephalitis with malacia caused by S. calchasi in a rock pigeon in Japan.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"906-910"},"PeriodicalIF":1.1,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11300125/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acaricidal activity of Erigeron acer L. root against Haemaphysalis longicornis and phytochemical profiling by liquid chromatography-tandem mass spectrometry. 刺五加（Erigeron acer L.）根对长角雉（Haemaphysalis longicornis）的杀螨活性及液相色谱-串联质谱法的植物化学成分分析。
IF 1.1 4区 农林科学
Journal of Veterinary Medical Science Pub Date : 2024-08-02 Epub Date: 2024-07-03 DOI: 10.1292/jvms.24-0090
Orkhon Banzragchgarav, Nanang R Ariefta, Rika Umemiya-Shirafuji, Punsantsogvoo Myagmarsuren, Badgar Battsetseg, Banzragch Battur, Javzan Batkhuu, Yoshifumi Nishikawa
{"title":"Acaricidal activity of Erigeron acer L. root against Haemaphysalis longicornis and phytochemical profiling by liquid chromatography-tandem mass spectrometry.","authors":"Orkhon Banzragchgarav, Nanang R Ariefta, Rika Umemiya-Shirafuji, Punsantsogvoo Myagmarsuren, Badgar Battsetseg, Banzragch Battur, Javzan Batkhuu, Yoshifumi Nishikawa","doi":"10.1292/jvms.24-0090","DOIUrl":"10.1292/jvms.24-0090","url":null,"abstract":"<p><p>The present study is focused on evaluating acaricidal activity and chemical compositions of Erigeron acer root, which was identified as a promising candidate among fifteen Mongolian plant extracts tested for acaricidal activity. The acaricidal effect was evaluated against Haemaphysalis longicornis, assessed for toxicity to normal human skin fibroblast, and analyzed for its chemical constituents. The acetone extract of E. acer root showed significant activity against H. longicornis, with a lethal concentration (LC<sub>50</sub>) of 5.31 mg/mL and low toxicity, evidenced by a cytotoxic concentration (CC<sub>50</sub>) of 267.00 µg/mL. Using liquid chromatography-tandem mass spectrometry and molecular networking, thirteen natural compounds were identified, including pyrrolidines, alkaloids, fatty acids, and flavonoids, highlighting the efficacy of E. acer root extract as an effective acaricide against H. longicornis and offering insights for developing new tick control solutions.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"897-905"},"PeriodicalIF":1.1,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11300131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信