Journal of Veterinary Medical Science最新文献_第10页

Association of toxin-producing Clostridioides difficile with piglet diarrhea and potential transmission to humans. 产毒艰难梭状芽孢杆菌与仔猪腹泻的关系以及向人类传播的可能性。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-07-02 Epub Date: 2024-05-27 DOI: 10.1292/jvms.24-0051

Kouki Takeichi, Akira Fukuda, Chika Shono, Noriyasu Ota, Chie Nakajima, Yasuhiko Suzuki, Masaru Usui

{"title":"Association of toxin-producing Clostridioides difficile with piglet diarrhea and potential transmission to humans.","authors":"Kouki Takeichi, Akira Fukuda, Chika Shono, Noriyasu Ota, Chie Nakajima, Yasuhiko Suzuki, Masaru Usui","doi":"10.1292/jvms.24-0051","DOIUrl":"10.1292/jvms.24-0051","url":null,"abstract":"The pathogenicity of Clostridioides difficile in piglets remains controversial. It is unknown whether C. difficile control helps protect piglet health. To clarify the association between C. difficile presence and piglet diarrhea, isolates were obtained from piglets with and without diarrhea. In addition, to determine the genetic relationship of C. difficile from pigs and humans, we performed whole-genome sequencing (WGS) of C. difficile isolates. Diarrheal and non-diarrheal stool samples were collected from neonatal piglets from five farms in Japan in 2021. To clarify the relationship between C. difficile derived from pigs and those from human clinical cases, WGS of C. difficile isolates was performed. Toxin-positive C. difficile were significantly more prevalent in piglets with diarrhea, although the overall frequency of C. difficile did not differ between piglets with and without diarrhea. This observation indicates an association between toxin-positive C. difficile and diarrhea in piglets. However, further studies are needed to establish a direct causal relationship and to explore other contributing factors to diarrhea in piglets. WGS results showed that C. difficile sequence type (ST) 11 including the hypervirulent PCR ribotype 078 isolates derived from Japanese pigs were closely related to ST11 of overseas strains (human clinical and animal-derived) and a Japanese human clinical strain. Toxin-positive C. difficile may cause diarrhea in piglets and hypervirulent C. difficile are spreading among pigs and human populations worldwide.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11251813/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Broad specificity of monoclonal IgA (TEPC15-IgA) for enteric bacteria via phosphorylcholine-mediated interaction. 通过磷酸胆碱介导的相互作用，单克隆 IgA（TEPC15-IgA）对肠道细菌具有广泛的特异性。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-07-02 Epub Date: 2024-06-04 DOI: 10.1292/jvms.23-0441

Saeka Koyama, Kaori Ito, Katsuki Usami, Shino Wada, Tsukasa Yamashita, Wakako Ikeda-Ohtsubo, Haruki Kitazawa, Ryota Hirakawa, Jahidul Islam, Mutsumi Furukawa, Tomonori Nochi

{"title":"Broad specificity of monoclonal IgA (TEPC15-IgA) for enteric bacteria via phosphorylcholine-mediated interaction.","authors":"Saeka Koyama, Kaori Ito, Katsuki Usami, Shino Wada, Tsukasa Yamashita, Wakako Ikeda-Ohtsubo, Haruki Kitazawa, Ryota Hirakawa, Jahidul Islam, Mutsumi Furukawa, Tomonori Nochi","doi":"10.1292/jvms.23-0441","DOIUrl":"10.1292/jvms.23-0441","url":null,"abstract":"Immunoglobulin A (IgA) is notable for its broad specificity toward multiple bacteria. Phosphorylcholine (PC) plays a role in the infection of pathogenic bacteria carrying PC and in the induction of IgA responses in the host immune system. The commercially available mouse monoclonal IgA, TEPC15-IgA, is a distinctive antibody with specificity for PC, warranting further exploration of its response to PC-bearing enteric bacteria. In this study, using 17 different enteric bacteria, including 3 aerobic and 14 anerobic bacteria that could be cultured in vitro, we confirmed that TEPC15-IgA recognizes 4 bacterial species: Lactobacillus taiwanensis, Limosilactobacillus frumenti, Streptococcus infantis, and Escherichia coli, although reactivity varied. Interestingly, TEPC15-IgA did not react with four of six Lactobacillus species used. Moreover, distinct target molecules associated with PC in L. taiwanensis and L. frumenti were evident, differing in molecular weight. These findings suggest that the natural generation of PC-specific IgA could prevent PC-mediated infections and potentially facilitate the formation of a microflora rich in indigenous bacteria with PC, particularly in the gastrointestinal tract.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11251817/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141262247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of different winter paddock management of Thoroughbred weanlings and yearlings in the cold region of Japan on physiological function, endocrine function and growth. 日本寒冷地区纯血马断奶幼马和一岁幼马的不同冬季围场管理对生理功能、内分泌功能和生长的影响。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-07-02 Epub Date: 2024-05-23 DOI: 10.1292/jvms.24-0083

Mutsuki Ishimaru, Takeru Tsuchiya, Yoshiro Endo, Akira Matsui, Hajime Ohmura, Harutaka Murase, Kenji Korosue, Fumio Sato, Kazuyoshi Taya

{"title":"Effects of different winter paddock management of Thoroughbred weanlings and yearlings in the cold region of Japan on physiological function, endocrine function and growth.","authors":"Mutsuki Ishimaru, Takeru Tsuchiya, Yoshiro Endo, Akira Matsui, Hajime Ohmura, Harutaka Murase, Kenji Korosue, Fumio Sato, Kazuyoshi Taya","doi":"10.1292/jvms.24-0083","DOIUrl":"10.1292/jvms.24-0083","url":null,"abstract":"Effects of different winter paddock management of Thoroughbred weanlings and yearlings in Hokkaido, Japan, which is extremely cold in winter, on physiological function, endocrine function and growth were investigated. They were divided into two groups; those kept outdoors for 22 hr in the paddock (22hr group) and those kept outdoors for 7 hr in daytime with walking exercise for 1 hr using the horse-walker (7hr+W group), and the changes in daily distance travelled, body temperature (BT), heart rate (HR), HR variability (HRV), endocrine function and growth parameters were compared between the two groups from November at the year of birth to January at 1 year of age. The 7hr+W group could travel almost the same distance as the 22hr group by using the horse-walker. The 22hr group had a lower rate of increase in body weight than the 7hr+W group in January. In addition, lower in BT and HR were observed, and HRV analysis showed an increase in high frequency power spectral density, indicating that parasympathetic nervous activity was dominant. And also, changes in circulating cortisol and thyroxine were not observed despite cold environment. On the other hand, the 7hr+W group had higher prolactin and insulin like growth factor than the 22hr group in January, and cortisol and thyroxine were also increased. Physiological and endocrinological findings from the present study indicate that the management of the 7hr+W group is effective in promoting growth and maintaining metabolism during the winter season.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11251821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141081861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Purification of living environments using photocatalysts: Inactivation of microorganisms and decomposition of allergens. 利用光催化剂净化生活环境：灭活微生物和分解过敏原。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-06-19 Epub Date: 2024-05-02 DOI: 10.1292/jvms.24-0055

Ryosuke Matsuura, Yoko Aida

{"title":"Purification of living environments using photocatalysts: Inactivation of microorganisms and decomposition of allergens.","authors":"Ryosuke Matsuura, Yoko Aida","doi":"10.1292/jvms.24-0055","DOIUrl":"10.1292/jvms.24-0055","url":null,"abstract":"Many emerging and re-emerging infectious diseases are prevalent, and the number of patients with allergies is increasing. Therefore, the importance of purifying the living environment is increasing. Photocatalysts undergo extreme redox reactions and decompose organic matter upon exposure to the excitation light. In contrast to ultraviolet light and disinfectants, which are standard methods for inactivating viruses and eliminating microorganisms, photocatalysts can decompose toxic substances, such as endotoxins and allergens, rendering them harmless to the human body. Photocatalysts have attracted significant attention as potential antiviral and antimicrobial agents. This review outlines the antiviral, antimicrobial, and anti-allergenic effects of photocatalysts. Especially, we have discussed the inactivation of SARS-CoV-2 in liquids and aerosols, elimination of Legionella pneumophila in liquids, decomposition of its endotoxin, decomposition of cat and dog allergens, and elimination of their allergenicity using photocatalysts. Furthermore, we discuss future perspectives on how photocatalysts can purify living environments, and how photocatalytic technology can be applied to companion animals and the livestock industry.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11187590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140859312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The first report of ovarian torsion causing intracoelomic hemorrhage and subsequent hemorrhagic shock in a captive Humboldt penguin (Spheniscus humboldti). 首次报道人工饲养的洪堡企鹅（Spheniscus humboldti）因卵巢扭转导致卵巢腔内出血，继而引发失血性休克。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-06-19 Epub Date: 2024-05-08 DOI: 10.1292/jvms.23-0501

Chika Shirakata, Hirotaka Kondo

引用次数: 0

Three cases of dogs with osteosarcoma of the forelimb treated with liquid nitrogen for limb-sparing surgery using autologous bone. 利用液氮对三例前肢骨肉瘤患犬进行治疗，以使用自体骨骼进行保肢手术。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-06-19 Epub Date: 2024-04-29 DOI: 10.1292/jvms.23-0390

Daisuke Yazawa, Masakazu Shimada, Nobuo Kanno, Shuji Suzuki, Takuya Yogo, Yasuji Harada, Yasushi Hara

引用次数: 0

The prevalence of porcine gastric ulcer and Helicobacter suis in Taiwan. 台湾猪胃溃疡和猪螺旋杆菌的流行情况。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-06-19 Epub Date: 2024-05-01 DOI: 10.1292/jvms.23-0403

Pei-Ju Lin, Che-Wei Liao, Hsin-Heng Chiang, Dan-Yuan Lo, Hung-Chih Kuo, Ching-Fen Wu

{"title":"The prevalence of porcine gastric ulcer and Helicobacter suis in Taiwan.","authors":"Pei-Ju Lin, Che-Wei Liao, Hsin-Heng Chiang, Dan-Yuan Lo, Hung-Chih Kuo, Ching-Fen Wu","doi":"10.1292/jvms.23-0403","DOIUrl":"10.1292/jvms.23-0403","url":null,"abstract":"Gastric ulcer is a common disease affecting pigs worldwide, with a prevalence reported as high as 93%. The cause of porcine gastric ulcer is multifactorial, with Helicobacter suis (H. suis) being considered as the primary pathogenic factor. To date, prevalence of H. suis resulting in porcine gastric ulcer in Taiwan has not been investigated. In this study, we collected 360 pig stomachs from the slaughterhouses. In addition, stomach tissues from the 88 diseased pigs submitted for necropsy were divided into symptomatic and asymptomatic groups. Gastric lesions were scored, and polymerase chain reaction was used to determine the occurrence of gastric ulcer and the prevalence of H. suis. The positive rate of H. suis in the samples from slaughtered pigs was 49.7%, and both infection of H. suis and the presence of gastric lesions were prone to occur in autumn. The positive rates of H. suis infection in the symptomatic and asymptomatic groups were 59.1% and 31.8%, respectively. Moreover, the proportion of the samples with gastroesophageal ulcer in the symptomatic group was 68.2%, predominantly observed in growing pigs. The incidence of the samples from the slaughterhouses with gastroesophageal erosion to ulceration revealed a significant difference between H. suis -infected and H. suis -uninfected pigs; however, there is no significant difference in the samples of diseased pigs. In conclusion, H. suis infection was associated with gastric ulcer in slaughtered pigs, but it was not the primary cause of gastroesophageal ulcer in diseased pigs with clinical symptoms.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11187585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of mammary gland tumors in bitches: effects of sodium dichloroacetate as neoadjuvant therapy. 母犬乳腺肿瘤的治疗：二氯乙酸钠作为新辅助疗法的效果。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-06-19 Epub Date: 2024-05-01 DOI: 10.1292/jvms.23-0393

Lucas Cavalli Kluthcovsky, Megan Jennifer, Tassia Mariane Merisio, Jorge Luiz Costa Castro, Jair Rodini Engracia Filho

{"title":"Treatment of mammary gland tumors in bitches: effects of sodium dichloroacetate as neoadjuvant therapy.","authors":"Lucas Cavalli Kluthcovsky, Megan Jennifer, Tassia Mariane Merisio, Jorge Luiz Costa Castro, Jair Rodini Engracia Filho","doi":"10.1292/jvms.23-0393","DOIUrl":"10.1292/jvms.23-0393","url":null,"abstract":"Mastectomy is the standard treatment for mammary gland tumors in dogs. In addition to traditional therapy, sodium dichloroacetate (DCA) can act as target therapy, as it may promote autophagy, reduce metastatic potential, and tumor proliferation in mammary tumor cell lines. This study aimed to analyze the effects of DCA as preoperative therapy for mammary tumors in bitches. Nineteen animals were selected, and they received DCA at a dose of 10 mg/kg orally every 12 hr, for 15 days. The periodic evaluation included hematological analysis (complete blood count and biochemical markers), evaluation of gastrointestinal adverse effects, evaluation of tumor volume, histopathological analysis, and immunohistochemical evaluation (Ki67 and cyclooxygenase-2/COX-2 markers). After treatment, there was a significant reduction in hematocrit (P=0.02) and leukocyte (P=0.04) means. Despite the variations for these two hematological parameters, the means remained within the reference range for the species. There were two cases of vomiting and one case of diarrhea. Most cases were classified as carcinoma in mixed tumor (n=7, 36.8%), followed by solid carcinoma (n=6, 31.6%). Nine cases (47.4%) showed reduced tumor volume, nine (47.4%) had stable disease, and one showed progressive disease. While there was no sample with a COX-2 score higher than 6, tumor samples with COX-2 scores 3 and 4 were significantly associated with stable disease or progression. DCA preoperative treatment for bitches with mammary gland tumors showed safety and potential cytoreduction in some cases.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11187584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case report of live-stranded rough-toothed dolphin (Steno bredanensis) with plastic debris ingestion on the Pacific coast of Japan. 日本太平洋沿岸活体搁浅粗齿海豚（Steno bredanensis）摄入塑料碎片的病例报告。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-06-01 Epub Date: 2024-05-07 DOI: 10.1292/jvms.23-0329

Chika Shirakata, Ryota Hanaue, Hiromi Ohtsubo, Akira Shiozaki, Kazue Ohishi, Soichiro Ishisaka, Dai Ohtsu

引用次数: 0

Molecular detection of Hepatozoon canis in dogs from Ibagué, Tolima. 在托利马省伊瓦圭市的狗中进行犬肝吸虫分子检测。

IF 1.1 4区农林科学

Journal of Veterinary Medical Science Pub Date : 2024-06-01 Epub Date: 2024-04-30 DOI: 10.1292/jvms.24-0035

Angélica Rocio Ramírez-Alvarado, Valentina Rueda-García, Iang Schroniltgen Rondón-Barragán

{"title":"Molecular detection of Hepatozoon canis in dogs from Ibagué, Tolima.","authors":"Angélica Rocio Ramírez-Alvarado, Valentina Rueda-García, Iang Schroniltgen Rondón-Barragán","doi":"10.1292/jvms.24-0035","DOIUrl":"10.1292/jvms.24-0035","url":null,"abstract":"The genus Hepatozoon consists of apicomplexan protozoans that affect mammals, birds, amphibians, and reptiles. In dogs, the Hepatozoon species include H. canis and H. americanum, which are transmitted by the Rhipicephalus sanguineus tick and cause nonspecific signs, such as fever, weight loss, diarrhea, and blood disorders. These protozoans have a worldwide distribution in Europe, Asia, Africa, and North and South America, including Colombia. The aim of this study was to determine the prevalence and risk factors associated with H. canis in the urban and rural areas of Ibagué, Colombia. Blood samples were collected from 308 dogs (180 rural areas and 128 urban areas). Collected data included dog breed, sex, age, environmental factors, and the presence of ectoparasites. A fragment of the 18S rRNA gene was amplified by PCR for detection of the pathogen and confirmed by sequencing. Among the 308 samples, 14 were positive (14/308, 4.5%) for the presence of H. canis. The partial sequence of the 18S rRNA gene showed identity values >98% with H. canis, forming a cluster with sequences from Latin America. An epidemiological survey found two protective factors: most of the time at home (P=0.055) and overnight stay at home (P=0.03). This is the first molecular study of the prevalence and phylogeny analysis of H. canis in Ibagué, Colombia. The findings may help determine risk factors and enhance our understanding of the geographic distribution of H. canis in Colombia.","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11187595/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140865667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0