{"title":"用帕罗霉素治疗隐孢子虫病引起的食管胃肠套叠。","authors":"Urarako Shimizu, Manabu Kurihara, Kenichi Tamukai, Kazutaka Yamada","doi":"10.1292/jvms.24-0483","DOIUrl":null,"url":null,"abstract":"<p><p>A 3-year-old captive corn snake (Pantherophis guttatus) was taken our veterinary clinic with a complaint of intermittent body swelling. Radiography revealed soft-tissue swelling, and ultrasonography confirmed intussusception of the digestive tract. Celiotomy revealed esophagogastric intussusception, which was subsequently corrected. Histopathological examination of gastric mucosal biopsy and polymerase chain reaction (PCR) from feces were revealed protozoan parasitism within the lesion and detected specific genes of Cryptosporidium spp. Oral administration of paromomycin at 100 mg/kg once daily for 10 days, subsequently twice weekly for 90 days under strict hygiene management were conducted as postoperative treatment. The snake was in good clinical health. PCR and ultrasonography for Cryptosporidium spp. 752 days after surgery showed no evidence of cryptosporidiosis.</p>","PeriodicalId":49959,"journal":{"name":"Journal of Veterinary Medical Science","volume":" ","pages":"389-393"},"PeriodicalIF":1.1000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964863/pdf/","citationCount":"0","resultStr":"{\"title\":\"Treatment of esophagogastric intussusception due to cryptosporidiosis using paromomycin in a corn snake (Pantherophis guttatus).\",\"authors\":\"Urarako Shimizu, Manabu Kurihara, Kenichi Tamukai, Kazutaka Yamada\",\"doi\":\"10.1292/jvms.24-0483\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A 3-year-old captive corn snake (Pantherophis guttatus) was taken our veterinary clinic with a complaint of intermittent body swelling. Radiography revealed soft-tissue swelling, and ultrasonography confirmed intussusception of the digestive tract. Celiotomy revealed esophagogastric intussusception, which was subsequently corrected. Histopathological examination of gastric mucosal biopsy and polymerase chain reaction (PCR) from feces were revealed protozoan parasitism within the lesion and detected specific genes of Cryptosporidium spp. Oral administration of paromomycin at 100 mg/kg once daily for 10 days, subsequently twice weekly for 90 days under strict hygiene management were conducted as postoperative treatment. The snake was in good clinical health. PCR and ultrasonography for Cryptosporidium spp. 752 days after surgery showed no evidence of cryptosporidiosis.</p>\",\"PeriodicalId\":49959,\"journal\":{\"name\":\"Journal of Veterinary Medical Science\",\"volume\":\" \",\"pages\":\"389-393\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964863/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Veterinary Medical Science\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://doi.org/10.1292/jvms.24-0483\",\"RegionNum\":4,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/2/7 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Veterinary Medical Science","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1292/jvms.24-0483","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/7 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
Treatment of esophagogastric intussusception due to cryptosporidiosis using paromomycin in a corn snake (Pantherophis guttatus).
A 3-year-old captive corn snake (Pantherophis guttatus) was taken our veterinary clinic with a complaint of intermittent body swelling. Radiography revealed soft-tissue swelling, and ultrasonography confirmed intussusception of the digestive tract. Celiotomy revealed esophagogastric intussusception, which was subsequently corrected. Histopathological examination of gastric mucosal biopsy and polymerase chain reaction (PCR) from feces were revealed protozoan parasitism within the lesion and detected specific genes of Cryptosporidium spp. Oral administration of paromomycin at 100 mg/kg once daily for 10 days, subsequently twice weekly for 90 days under strict hygiene management were conducted as postoperative treatment. The snake was in good clinical health. PCR and ultrasonography for Cryptosporidium spp. 752 days after surgery showed no evidence of cryptosporidiosis.
期刊介绍：
JVMS is a peer-reviewed journal and publishes a variety of papers on veterinary science from basic research to applied science and clinical research. JVMS is published monthly and consists of twelve issues per year. Papers are from the areas of anatomy, physiology, pharmacology, toxicology, pathology, immunology, microbiology, virology, parasitology, internal medicine, surgery, clinical pathology, theriogenology, avian disease, public health, ethology, and laboratory animal science. Although JVMS has played a role in publishing the scientific achievements of Japanese researchers and clinicians for many years, it now also accepts papers submitted from all over the world.
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