Korean Journal of Pathology最新文献_第5页

Inflammatory myofibroblastic tumor of the thyroid gland: a brief case report. 甲状腺炎性肌成纤维细胞瘤1例报告。

Korean Journal of Pathology Pub Date : 2014-08-01 Epub Date: 2014-08-26 DOI: 10.4132/KoreanJPathol.2014.48.4.319

Hye Jeong Kim, Jong In Na, Ji Shin Lee, Dong Hyeok Cho, Jin Seong Cho

引用次数: 5

Dedifferentiated endometrioid adenocarcinoma of the uterus: highly aggressive and poor prognostic tumor. 子宫去分化子宫内膜样腺癌:侵袭性强，预后差的肿瘤。

Korean Journal of Pathology Pub Date : 2014-08-01 Epub Date: 2014-08-26 DOI: 10.4132/KoreanJPathol.2014.48.4.327

Shin Young Park, Moon Hyang Park, Hyoung Suk Ko, Eun Jung Cha, Jang Sihn Sohn, Un Suk Jung, Chul Jung Kim, Jin Suk Kim

引用次数: 13

Chordoid meningioma in a pediatric patient with tuberous sclerosis complex. 小儿结节性硬化症合并脊索样脑膜瘤1例。

Korean Journal of Pathology Pub Date : 2014-08-01 Epub Date: 2014-08-26 DOI: 10.4132/KoreanJPathol.2014.48.4.302

Jiwon Lee, Hee Joon Yu, Jeehun Lee, Ji Hye Kim, Hyung Jin Shin, Yeon-Lim Suh, Munhyang Lee

{"title":"Chordoid meningioma in a pediatric patient with tuberous sclerosis complex.","authors":"Jiwon Lee, Hee Joon Yu, Jeehun Lee, Ji Hye Kim, Hyung Jin Shin, Yeon-Lim Suh, Munhyang Lee","doi":"10.4132/KoreanJPathol.2014.48.4.302","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.4.302","url":null,"abstract":"Meningeal tumors are rare in childhood, comprising less than 4.2% of all pediatric primary intracranial tumors.1 Fourteen histological subtypes of meningiomas exist in the World Health Organization (WHO) classification system.2 Chordoid meningioma (CM) is a rare meningiomal variant characterized histologically by features that mimic chordoma and other chordoid neoplasms.2 Chordoid meningiomal tumors tend to exhibit local recurrence and aggressive behavior, although they typically show morphologically benign features. \u0000 \u0000In a tuberous sclerosis complex (TSC) patient, hamartomas can occur in multiple organs and cause diverse clinical symptoms. Cortical tubers, subependymal nodules (SENs) and subependymal giant cell astrocytomas (SEGAs) are representative lesions of TSC and can be detected by magnetic resonance imaging (MRI) of the brain.3 SEGA lesions have been found to occur in approximately 6.1% to 18.5% of TSC patients, and account for 90% of all intracranial tumors associated with TSC.4 SEGA lesions are commonly located in the foramen of Monro or the periventricular region,5 and can cause loss of vision, papillary edemas, intracranial calcification, and hydrocephalus.6 The primary method for treating SEGA lesions consists of surgical resection of the tumors; complete and early surgical removal of tumors has been shown to be the most important prognostic factor.6 \u0000 \u0000Childhood CM has been shown to account for only ~0.5-1% of all meningiomas, with intraventricular occurrence of CM reported in only 27 children to date.2,7 Also, CM has not been reported in any TSC patients to date. Here we report a case of intraventricular CM, which appeared highly similar to SEGA in brain MRI scans, in a child with TSC.","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 4","pages":"302-6"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.4.302","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32662796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Perivascular epithelioid cell tumor arising in the sacrum: a case report. 骶骨血管周围上皮样细胞瘤1例。

Korean Journal of Pathology Pub Date : 2014-08-01 Epub Date: 2014-08-26 DOI: 10.4132/KoreanJPathol.2014.48.4.331

Yoon Sung Bae, Se Hoon Kim

引用次数: 0

Unilateral Pigmented Extramammary Paget's Disease of the Axilla Associated with a Benign Mole: A Case Study and a Review of Literature. 腋窝单侧色素性乳腺外佩吉特病合并良性痣:一例研究及文献回顾

Korean Journal of Pathology Pub Date : 2014-08-01 Epub Date: 2014-08-26 DOI: 10.4132/KoreanJPathol.2014.48.4.292

Aleem Ladak, Maria Bramley, Sami Titi

{"title":"Unilateral Pigmented Extramammary Paget's Disease of the Axilla Associated with a Benign Mole: A Case Study and a Review of Literature.","authors":"Aleem Ladak, Maria Bramley, Sami Titi","doi":"10.4132/KoreanJPathol.2014.48.4.292","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.4.292","url":null,"abstract":"Pigmented extramammary Paget's disease (PEMPD) is an uncommon intraepithelial adenocarcinoma and a rare variant of Paget's disease affecting skin that is rich in apocrine sweat glands such as the axilla, perianal region and vulva. It most commonly occurs in postmenopausal women and presents as a superficial pigmented scaly macule, mimicking a melanocytic lesion. The histological presentation is adenocarcinoma in situ with an increased number of melanocytes scattered between the Paget's cells. Therefore, PEMPD may be misdiagnosed as a melanocytic tumour both clinically and histologically. The tumour cells are usually positive for cytokeratin 7, epithelial membrane antigen, Cam 5.2, HER2, and mucicarmine stain while S100 and human melanoma black-45 highlight the processes of reactive dendritic cells. The association between Paget's cells and intratumoural reactive melanocytes is still unclear. We report our first case of PEMPD associated with an intradermal naevus involving the axilla in a 63-year-old woman. ","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 4","pages":"292-6"},"PeriodicalIF":0.0,"publicationDate":"2014-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.4.292","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32662794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Anaplastic Transformation of Papillary Thyroid Carcinoma in a Young Man: A Case Study with Immunohistochemical and BRAF Analysis. 年轻男性甲状腺乳头状癌间变性:免疫组织化学和BRAF分析的案例研究。

Korean Journal of Pathology Pub Date : 2014-06-01 Epub Date: 2014-06-26 DOI: 10.4132/KoreanJPathol.2014.48.3.234

Ji Hye Park, Hyeong Ju Kwon, Cheong Soo Park, SoonWon Hong

{"title":"Anaplastic Transformation of Papillary Thyroid Carcinoma in a Young Man: A Case Study with Immunohistochemical and BRAF Analysis.","authors":"Ji Hye Park, Hyeong Ju Kwon, Cheong Soo Park, SoonWon Hong","doi":"10.4132/KoreanJPathol.2014.48.3.234","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.3.234","url":null,"abstract":"This study reports a case of anaplastic transformation from a well-differentiated thyroid carcinoma in a young patient. The first recurrent tissue contained poorly differentiated foci that revealed lower thyroglobulin, thyroid transcription factor 1 (TTF-1), and galectin-3 expression than the well-differentiated area. However there was no increased p53 or Ki-67 expression in the poorly differentiated foci, nor in the well-differentiated area. The tissue subsequently relapsed and revealed only anaplastic features, complete loss of thyroglobulin, TTF-1, and galectin-3 expression and revealed an increase in p53 and Ki-67 expression. The BRAF V600E and BRAF V600V mutation were found in the initially diagnosed papillary thyroid carcinoma and the poorly differentiated foci of the recurring papillary thyroid carcinoma; however, only the BRAF V600V mutation was found in the anaplastic carcinoma. These results suggest that overexpression of p53 and Ki-67 contributed to the anaplastic transformation. We also found that the BRAF type changed during the tumor relapse. ","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 3","pages":"234-40"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.3.234","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32494206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Bilateral stafne bone cavity in the anterior mandible with heterotopic salivary gland tissue: a case report. 前颌骨双侧骨腔伴异位唾液腺组织1例。

Korean Journal of Pathology Pub Date : 2014-06-01 Epub Date: 2014-06-26 DOI: 10.4132/KoreanJPathol.2014.48.3.248

Hyunchul Kim, Jae Yeon Seok, Sangho Lee, Jungsuk An, Na Rae Kim, Dong Hae Chung, Hyun Yee Cho, Seung Yeon Ha

引用次数: 17

Well-differentiated papillary mesothelioma of the tunica vaginalis: a case study and review of the literature. 阴道膜高分化乳头状间皮瘤:个案研究及文献回顾。

Korean Journal of Pathology Pub Date : 2014-06-01 Epub Date: 2014-06-26 DOI: 10.4132/KoreanJPathol.2014.48.3.225

Seyda Erdogan, Arbil Acikalin, Handan Zeren, Gulfılız Gonlusen, Suzan Zorludemir, Volkan Izol

引用次数: 15

Low-grade adenosquamous carcinoma of the breast with diverse expression patterns of myoepithelial cell markers on immunohistochemistry: a case study. 低级别乳腺腺鳞癌的不同表达模式的肌上皮细胞标记免疫组织化学:一个案例研究。

Korean Journal of Pathology Pub Date : 2014-06-01 Epub Date: 2014-06-26 DOI: 10.4132/KoreanJPathol.2014.48.3.229

Yoon Jin Cha, Gi Jeong Kim, Byeong-Woo Park, Ja Seung Koo

{"title":"Low-grade adenosquamous carcinoma of the breast with diverse expression patterns of myoepithelial cell markers on immunohistochemistry: a case study.","authors":"Yoon Jin Cha, Gi Jeong Kim, Byeong-Woo Park, Ja Seung Koo","doi":"10.4132/KoreanJPathol.2014.48.3.229","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.3.229","url":null,"abstract":"This paper reports a case of low-grade adenosquamous carcinoma (LGASC) arising in a 69-year-old woman, who presented with a 1-cm palpable mass on her right breast. Core needle biopsy diagnosed the mass as a fibroadenoma. After six months, the mass increased in size, and the patient received subsequent mammotome excision. On microscopic examination, bland-looking small glands were infiltrating into the fibrotic stroma with lymphocytic infiltrates at the periphery. Hematoxylin and eosin staining revealed relatively easily detectable myoepithelial cells along the outside in each of the glandular structures with variable degrees of squamous metaplasia. Based on histologic features, the patient was diagnosed with LGASC. LGASC is a rare variant of metaplastic carcinoma, which is characterized by a favorable prognosis. Due to the bland cytology and presence of myoepithelial cells, LGASC can be misdiagnosed as benign lesion. Additionally, inconsistent expression of myoepithelial markers could aid the diagnosis of LGASC. ","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 3","pages":"229-33"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.3.229","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32494205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Primary gastric histiocytic sarcoma reminiscent of inflammatory pseudotumor: a case report with review of the literature. 原发性胃组织细胞肉瘤伴炎性假瘤:1例报告并文献复习。

Korean Journal of Pathology Pub Date : 2014-06-01 Epub Date: 2014-06-26 DOI: 10.4132/KoreanJPathol.2014.48.3.258

Dakeun Lee, Young-Bae Kim, Sook Hee Chung, Sang-Ryung Lee, Cheul Su Byun, Sang-Uk Han, Jae Ho Han

{"title":"Primary gastric histiocytic sarcoma reminiscent of inflammatory pseudotumor: a case report with review of the literature.","authors":"Dakeun Lee, Young-Bae Kim, Sook Hee Chung, Sang-Ryung Lee, Cheul Su Byun, Sang-Uk Han, Jae Ho Han","doi":"10.4132/KoreanJPathol.2014.48.3.258","DOIUrl":"https://doi.org/10.4132/KoreanJPathol.2014.48.3.258","url":null,"abstract":"Histiocytic sarcoma is a malignant proliferation of cells showing similar morphologic and immunophenotypic features to mature tissue histiocytes. 1 It is a very rare neoplasm, and only a limited number of cases have been reported. Although it occurs in lymph nodes, the majority of cases present in extranodal sites, most commonly the intestinal tract, skin, and soft tissues. 2 In the intestinal tract, primary gastric involvement is exceptional; only a handful of cases have been reported in the English literature. 2-6 In all of these cases, the neoplastic cells were highly atypical, and malignancy was easily suggested based on the morphology. In the case presented here, diagnosis was a challenge due to the lack of a high degree of atypia or pleomorphism of the tumor cells. Herein, we report a case of primary gastric histiocytic sarcoma masquerading as an inflam matory pseudotumor. We also present the clinical characteristics of previously reported gastric histiocytic sarcomas by literature review.","PeriodicalId":49936,"journal":{"name":"Korean Journal of Pathology","volume":"48 3","pages":"258-62"},"PeriodicalIF":0.0,"publicationDate":"2014-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4132/KoreanJPathol.2014.48.3.258","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32495697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5