Mathematical Biosciences and Engineering最新文献

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Modeling free tumor growth: Discrete, continuum, and hybrid approaches to interpreting cancer development. 肿瘤自由生长建模:解读癌症发展的离散、连续和混合方法。
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-19 DOI: 10.3934/mbe.2024292
Dashmi Singh, Dana Paquin
{"title":"Modeling free tumor growth: Discrete, continuum, and hybrid approaches to interpreting cancer development.","authors":"Dashmi Singh, Dana Paquin","doi":"10.3934/mbe.2024292","DOIUrl":"10.3934/mbe.2024292","url":null,"abstract":"<p><p>Tumor growth dynamics serve as a critical aspect of understanding cancer progression and treatment response to mitigate one of the most pressing challenges in healthcare. The in silico approach to understanding tumor behavior computationally provides an efficient, cost-effective alternative to wet-lab examinations and are adaptable to different environmental conditions, time scales, and unique patient parameters. As a result, this paper explored modeling of free tumor growth in cancer, surveying contemporary literature on continuum, discrete, and hybrid approaches. Factors like predictive power and high-resolution simulation competed against drawbacks like simulation load and parameter feasibility in these models. Understanding tumor behavior in different scenarios and contexts became the first step in advancing cancer research and revolutionizing clinical outcomes.</p>","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6659-6693"},"PeriodicalIF":2.6,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction notice to "A video images-aware knowledge extraction method for intelligent healthcare management of basketball players" [Mathematical Biosciences and Engineering 20(2) (2023) 1919-1937]. 用于篮球运动员智能健康管理的视频图像感知知识提取方法"[《数学生物科学与工程》20(2)(2023)1919-1937]的撤稿通知。
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-18 DOI: 10.3934/mbe.2024291
Editorial Office Of Mathematical Biosciences And Engineering
{"title":"Retraction notice to \"A video images-aware knowledge extraction method for intelligent healthcare management of basketball players\" [<i>Mathematical Biosciences and Engineering</i> 20(2) (2023) 1919-1937].","authors":"Editorial Office Of Mathematical Biosciences And Engineering","doi":"10.3934/mbe.2024291","DOIUrl":"10.3934/mbe.2024291","url":null,"abstract":"","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6658"},"PeriodicalIF":2.6,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improved optimizer with deep learning model for emotion detection and classification. 利用深度学习模型改进优化情绪检测和分类。
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-17 DOI: 10.3934/mbe.2024290
C Willson Joseph, G Jaspher Willsie Kathrine, Shanmuganathan Vimal, S Sumathi, Danilo Pelusi, Xiomara Patricia Blanco Valencia, Elena Verdú
{"title":"Improved optimizer with deep learning model for emotion detection and classification.","authors":"C Willson Joseph, G Jaspher Willsie Kathrine, Shanmuganathan Vimal, S Sumathi, Danilo Pelusi, Xiomara Patricia Blanco Valencia, Elena Verdú","doi":"10.3934/mbe.2024290","DOIUrl":"https://doi.org/10.3934/mbe.2024290","url":null,"abstract":"<p><p>Facial emotion recognition (FER) is largely utilized to analyze human emotion in order to address the needs of many real-time applications such as computer-human interfaces, emotion detection, forensics, biometrics, and human-robot collaboration. Nonetheless, existing methods are mostly unable to offer correct predictions with a minimum error rate. In this paper, an innovative facial emotion recognition framework, termed extended walrus-based deep learning with Botox feature selection network (EWDL-BFSN), was designed to accurately detect facial emotions. The main goals of the EWDL-BFSN are to identify facial emotions automatically and effectively by choosing the optimal features and adjusting the hyperparameters of the classifier. The gradient wavelet anisotropic filter (GWAF) can be used for image pre-processing in the EWDL-BFSN model. Additionally, SqueezeNet is used to extract significant features. The improved Botox optimization algorithm (IBoA) is then used to choose the best features. Lastly, FER and classification are accomplished through the use of an enhanced optimization-based kernel residual 50 (EK-ResNet50) network. Meanwhile, a nature-inspired metaheuristic, walrus optimization algorithm (WOA) is utilized to pick the hyperparameters of EK-ResNet50 network model. The EWDL-BFSN model was trained and tested with publicly available CK+ and FER-2013 datasets. The Python platform was applied for implementation, and various performance metrics such as accuracy, sensitivity, specificity, and F1-score were analyzed with state-of-the-art methods. The proposed EWDL-BFSN model acquired an overall accuracy of 99.37 and 99.25% for both CK+ and FER-2013 datasets and proved its superiority in predicting facial emotions over state-of-the-art methods.</p>","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6631-6657"},"PeriodicalIF":2.6,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A topical VAEGAN-IHMM approach for automatic story segmentation. 用于自动故事分割的专题 VAEGAN-IHMM 方法。
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-16 DOI: 10.3934/mbe.2024289
Jia Yu, Huiling Peng, Guoqiang Wang, Nianfeng Shi
{"title":"A topical VAEGAN-IHMM approach for automatic story segmentation.","authors":"Jia Yu, Huiling Peng, Guoqiang Wang, Nianfeng Shi","doi":"10.3934/mbe.2024289","DOIUrl":"https://doi.org/10.3934/mbe.2024289","url":null,"abstract":"<p><p>Feature representations with rich topic information can greatly improve the performance of story segmentation tasks. VAEGAN offers distinct advantages in feature learning by combining variational autoencoder (VAE) and generative adversarial network (GAN), which not only captures intricate data representations through VAE's probabilistic encoding and decoding mechanism but also enhances feature diversity and quality via GAN's adversarial training. To better learn topical domain representation, we used a topical classifier to supervise the training process of VAEGAN. Based on the learned feature, a segmentor splits the document into shorter ones with different topics. Hidden Markov model (HMM) is a popular approach for story segmentation, in which stories are viewed as instances of topics (hidden states). The number of states has to be set manually but it is often unknown in real scenarios. To solve this problem, we proposed an infinite HMM (IHMM) approach which utilized an HDP prior on transition matrices over countably infinite state spaces to automatically infer the state's number from the data. Given a running text, a Blocked Gibbis sampler labeled the states with topic classes. The position where the topic changes was a story boundary. Experimental results on the TDT2 corpus demonstrated that the proposed topical VAEGAN-IHMM approach was significantly better than the traditional HMM method in story segmentation tasks and achieved state-of-the-art performance.</p>","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6608-6630"},"PeriodicalIF":2.6,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stochastic assessment of temperature-CO2 causal relationship in climate from the Phanerozoic through modern times. 从新生代到现代气候中温度-二氧化碳因果关系的随机评估。
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-10 DOI: 10.3934/mbe.2024287
Demetris Koutsoyiannis
{"title":"Stochastic assessment of temperature-CO2 causal relationship in climate from the Phanerozoic through modern times.","authors":"Demetris Koutsoyiannis","doi":"10.3934/mbe.2024287","DOIUrl":"https://doi.org/10.3934/mbe.2024287","url":null,"abstract":"<p><p>As a result of recent research, a new stochastic methodology of assessing causality was developed. Its application to instrumental measurements of temperature (<i>T</i>) and atmospheric carbon dioxide concentration ([CO<sub>2</sub>]) over the last seven decades provided evidence for a unidirectional, potentially causal link between <i>T</i> as the cause and [CO<sub>2</sub>] as the effect. Here, I refine and extend this methodology and apply it to both paleoclimatic proxy data and instrumental data of <i>T</i> and [CO<sub>2</sub>]. Several proxy series, extending over the Phanerozoic or parts of it, gradually improving in accuracy and temporal resolution up to the modern period of accurate records, are compiled, paired, and analyzed. The extensive analyses made converge to the single inference that change in temperature leads, and that in carbon dioxide concentration lags. This conclusion is valid for both proxy and instrumental data in all time scales and time spans. The time scales examined begin from annual and decadal for the modern period (instrumental data) and the last two millennia (proxy data), and reach one million years for the most sparse time series for the Phanerozoic. The type of causality appears to be unidirectional, <i>T</i>→[CO<sub>2</sub>], as in earlier studies. The time lags found depend on the time span and time scale and are of the same order of magnitude as the latter. These results contradict the conventional wisdom, according to which the temperature rise is caused by [CO<sub>2</sub>] increase.</p>","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6560-6602"},"PeriodicalIF":2.6,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in computational methods for process and data mining in healthcare. 医疗保健流程和数据挖掘计算方法的进展。
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-10 DOI: 10.3934/mbe.2024288
Marco Pegoraro, Elisabetta Benevento, Davide Aloini, Wil M P van der Aalst
{"title":"Advances in computational methods for process and data mining in healthcare.","authors":"Marco Pegoraro, Elisabetta Benevento, Davide Aloini, Wil M P van der Aalst","doi":"10.3934/mbe.2024288","DOIUrl":"https://doi.org/10.3934/mbe.2024288","url":null,"abstract":"","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6603-6607"},"PeriodicalIF":2.6,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction notice to "ICG fluorescence imaging technology in laparoscopic liver resection for primary liver cancer: A meta-analysis" [Mathematical Biosciences and Engineering 20(9) (2023) 15918-15941]. ICG荧光成像技术在原发性肝癌腹腔镜肝切除术中的应用》撤稿通知:荟萃分析" [Mathematical Biosciences and Engineering 20(9) (2023) 15918-15941].
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-09 DOI: 10.3934/mbe.2024286
Editorial Office Of Mathematical Biosciences And Engineering
{"title":"Retraction notice to \"ICG fluorescence imaging technology in laparoscopic liver resection for primary liver cancer: A meta-analysis\" [<i>Mathematical Biosciences and Engineering</i> 20(9) (2023) 15918-15941].","authors":"Editorial Office Of Mathematical Biosciences And Engineering","doi":"10.3934/mbe.2024286","DOIUrl":"10.3934/mbe.2024286","url":null,"abstract":"","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6559"},"PeriodicalIF":2.6,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Possible counter-intuitive impact of local vaccine mandates for vaccine-preventable infectious diseases. 地方疫苗接种规定对疫苗可预防传染病可能产生的反直觉影响。
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-08 DOI: 10.3934/mbe.2024284
Maddalena Donà, Pieter Trapman
{"title":"Possible counter-intuitive impact of local vaccine mandates for vaccine-preventable infectious diseases.","authors":"Maddalena Donà, Pieter Trapman","doi":"10.3934/mbe.2024284","DOIUrl":"https://doi.org/10.3934/mbe.2024284","url":null,"abstract":"<p><p>We modeled the impact of local vaccine mandates on the spread of vaccine-preventable infectious diseases, which in the absence of vaccines will mainly affect children. Examples of such diseases are measles, rubella, mumps, and pertussis. To model the spread of the pathogen, we used a stochastic SIR (susceptible, infectious, recovered) model with two levels of mixing in a closed population, often referred to as the household model. In this model, individuals make local contacts within a specific small subgroup of the population (e.g., within a household or a school class), while they also make global contacts with random people in the population at a much lower rate than the rate of local contacts. We considered what would happen if schools were given freedom to impose vaccine mandates on all of their pupils, except for the pupils that were exempt from vaccination because of medical reasons. We investigated first how such a mandate affected the probability of an outbreak of a disease. Furthermore, we focused on the probability that a pupil that was medically exempt from vaccination, would get infected during an outbreak. We showed that if the population vaccine coverage was close to the herd-immunity level, then both probabilities may increase if local vaccine mandates were implemented. This was caused by unvaccinated pupils possibly being moved to schools without mandates.</p>","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6521-6538"},"PeriodicalIF":2.6,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Forecasting hospital discharges for respiratory conditions in Costa Rica using climate and pollution data. 利用气候和污染数据预测哥斯达黎加呼吸系统疾病的出院人数。
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-08 DOI: 10.3934/mbe.2024285
Shu Wei Chou-Chen, Luis A Barboza
{"title":"Forecasting hospital discharges for respiratory conditions in Costa Rica using climate and pollution data.","authors":"Shu Wei Chou-Chen, Luis A Barboza","doi":"10.3934/mbe.2024285","DOIUrl":"https://doi.org/10.3934/mbe.2024285","url":null,"abstract":"<p><p>Respiratory diseases represent one of the most significant economic burdens on healthcare systems worldwide. The variation in the increasing number of cases depends greatly on climatic seasonal effects, socioeconomic factors, and pollution. Therefore, understanding these variations and obtaining precise forecasts allows health authorities to make correct decisions regarding the allocation of limited economic and human resources. We aimed to model and forecast weekly hospitalizations due to respiratory conditions in seven regional hospitals in Costa Rica using four statistical learning techniques (Random Forest, XGboost, Facebook's Prophet forecasting model, and an ensemble method combining the above methods), along with 22 climate change indices and aerosol optical depth as an indicator of pollution. Models were trained using data from 2000 to 2018 and were evaluated using data from 2019 as testing data. During the training period, we set up 2-year sliding windows and a 1-year assessment period, along with the grid search method to optimize hyperparameters for each model. The best model for each region was selected using testing data, based on predictive precision and to prevent overfitting. Prediction intervals were then computed using conformal inference. The relative importance of all climatic variables was computed for the best model, and similar patterns in some of the seven regions were observed based on the selected model. Finally, reliable predictions were obtained for each of the seven regional hospitals.</p>","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6539-6558"},"PeriodicalIF":2.6,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemic control by social distancing and vaccination: Optimal strategies and remarks on the COVID-19 Italian response policy. 通过拉开社会距离和接种疫苗控制疫情:意大利 COVID-19 应对政策的最佳战略和评论。
IF 2.6 4区 工程技术
Mathematical Biosciences and Engineering Pub Date : 2024-07-03 DOI: 10.3934/mbe.2024283
Alberto d'Onofrio, Mimmo Iannelli, Piero Manfredi, Gabriela Marinoschi
{"title":"Epidemic control by social distancing and vaccination: Optimal strategies and remarks on the COVID-19 Italian response policy.","authors":"Alberto d'Onofrio, Mimmo Iannelli, Piero Manfredi, Gabriela Marinoschi","doi":"10.3934/mbe.2024283","DOIUrl":"https://doi.org/10.3934/mbe.2024283","url":null,"abstract":"<p><p>After the many failures in the control of the COVID-19 pandemic, identifying robust principles of epidemic control will be key in future preparedness. In this work, we propose an optimal control model of an age-of-infection transmission model under a two-phase control regime where social distancing is the only available control tool in the first phase, while the second phase also benefits from the arrival of vaccines. We analyzed the problem by an ad-hoc numerical algorithm under a strong hypothesis implying a high degree of prioritization to the protection of health from the epidemic attack, which we termed the \"low attack rate\" hypothesis. The outputs of the model were also compared with the data from the Italian COVID-19 experience to provide a crude assessment of the goodness of the enacted interventions prior to the onset of the Omicron variant.</p>","PeriodicalId":49870,"journal":{"name":"Mathematical Biosciences and Engineering","volume":"21 7","pages":"6493-6520"},"PeriodicalIF":2.6,"publicationDate":"2024-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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