在随机流行病模型中捕捉季节性传播的建模方法的探索。

IF 2.6 4区 工程技术 Q1 Mathematics
Mahmudul Bari Hridoy
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引用次数: 0

摘要

传染病发病率的季节性变化是一个公认的现象,受气候变化、社会行为和影响宿主易感性和传播率的生态相互作用等因素的驱动。虽然季节性在形成流行病学动态方面发挥着重要作用,但在实证和理论研究中往往被忽视。将季节性参数纳入传染病的数学模型对于准确捕捉疾病动态、增强这些模型的预测能力和制定成功的控制策略至关重要。在本文中,我强调了将季节性纳入疾病传播的关键建模方法,包括正弦函数,周期性分段线性函数,傅立叶级数展开,高斯函数和数据驱动方法。根据这些方法的灵活性、复杂性和捕捉在现实世界流行病中观察到的不同季节性模式的能力对其进行评估。对比分析展示了每种方法的相对优势和局限性,并通过现实世界的例子加以支持。此外,通过数值模拟证明了具有季节性传播的随机易感-感染-恢复(SIR)模型。重要的结果度量,如基本和瞬时繁殖数以及从马尔可夫链的分支过程近似中得出的疾病爆发的概率,也被提出来说明季节性对疾病动力学的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An exploration of modeling approaches for capturing seasonal transmission in stochastic epidemic models.

Seasonal variations in the incidence of infectious diseases are a well-established phenomenon, driven by factors such as climate changes, social behaviors, and ecological interactions that influence host susceptibility and transmission rates. While seasonality plays a significant role in shaping epidemiological dynamics, it is often overlooked in both empirical and theoretical studies. Incorporating seasonal parameters into mathematical models of infectious diseases is crucial for accurately capturing disease dynamics, enhancing the predictive power of these models, and developing successful control strategies. In this paper, I highlight key modeling approaches for incorporating seasonality into disease transmission, including sinusoidal functions, periodic piecewise linear functions, Fourier series expansions, Gaussian functions, and data-driven methods. These approaches are evaluated in terms of their flexibility, complexity, and ability to capture distinct seasonal patterns observed in real-world epidemics. A comparative analysis showcases the relative strengths and limitations of each method, supported by real-world examples. Additionally, a stochastic Susceptible-Infected-Recovered (SIR) model with seasonal transmission is demonstrated through numerical simulations. Important outcome measures, such as the basic and instantaneous reproduction numbers and the probability of a disease outbreak derived from the branching process approximation of the Markov chain, are also presented to illustrate the impact of seasonality on disease dynamics.

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来源期刊
Mathematical Biosciences and Engineering
Mathematical Biosciences and Engineering 工程技术-数学跨学科应用
CiteScore
3.90
自引率
7.70%
发文量
586
审稿时长
>12 weeks
期刊介绍: Mathematical Biosciences and Engineering (MBE) is an interdisciplinary Open Access journal promoting cutting-edge research, technology transfer and knowledge translation about complex data and information processing. MBE publishes Research articles (long and original research); Communications (short and novel research); Expository papers; Technology Transfer and Knowledge Translation reports (description of new technologies and products); Announcements and Industrial Progress and News (announcements and even advertisement, including major conferences).
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