Medical Engineering & Physics最新文献_第10页

A mechanics-based model for predicting flexible needle bending with large curvature in soft tissue 基于力学的软组织大曲率柔性针弯曲预测模型

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-19 DOI: 10.1016/j.medengphy.2024.104156

Yan-Jiang Zhao , Ye-Xin Jin , Chao Wen , Yong-De Zhang , He Zhang

引用次数: 0

Evaluation of the accuracy of a UWB tracker for in-home positioning for older adults 评估用于老年人居家定位的 UWB 跟踪器的准确性

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-19 DOI: 10.1016/j.medengphy.2024.104155

Linna Qian , Andrew Chan , Joanne Cai , Justin Lewicke , Geoff Gregson , Michael Lipsett , Adriana Rios Rincón

{"title":"Evaluation of the accuracy of a UWB tracker for in-home positioning for older adults","authors":"Linna Qian , Andrew Chan , Joanne Cai , Justin Lewicke , Geoff Gregson , Michael Lipsett , Adriana Rios Rincón","doi":"10.1016/j.medengphy.2024.104155","DOIUrl":"10.1016/j.medengphy.2024.104155","url":null,"abstract":"<div><p>The population of older adults is rapidly growing. In-home monitoring systems have been used to support aging-in-place. Ambient sensors or wearable localizers can be used but may be too low resolution, while camera systems are invasive to privacy. Ultra-wideband (UWB) localization offers precise positioning by placing anchors throughout the house and wearing a tag that is tracked by the anchors. In this study, the accuracy of UWB for indoor tracking was evaluated in a motion capture gait lab and in a mock condo in the Glenrose Rehabilitation Hospital. First, the configuration of UWB was tested, changing factors related to sampling time, anchor placement and line-of-sight. Comparing these factors to the configurations recommended by the manufacturer guidelines, accuracies remained within 14 cm. We then performed static and dynamic accuracy tests, with dynamic testing comprised of rolling and walking motions. In the motion capture lab, we found localization accuracies of 7.0 ± 11.1 cm while in the mock condo, we found accuracies of 27.3 ± 12.9 cm. Dynamic testing with rolling motions had an average of 19.1 ± 1.6 cm while walking was 20.5 ± 4.2 cm. The mean accuracy of UWB is within the 30 cm target for indoor localization.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140275681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Region-specific delamination strength of ascending thoracic aortic aneurysm of elderly hypertensive patients with bicuspid and tricuspid aortic valves 患有二尖瓣和三尖瓣主动脉瓣的老年高血压患者升胸主动脉瘤的特定区域分层强度

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-19 DOI: 10.1016/j.medengphy.2024.104157

Zhi Zhang , Xiaojuan Xu , Tieyan Li , Yuan-Feng Xin , Jianhua Tong

{"title":"Region-specific delamination strength of ascending thoracic aortic aneurysm of elderly hypertensive patients with bicuspid and tricuspid aortic valves","authors":"Zhi Zhang , Xiaojuan Xu , Tieyan Li , Yuan-Feng Xin , Jianhua Tong","doi":"10.1016/j.medengphy.2024.104157","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104157","url":null,"abstract":"<div><p>Both ageing and hypertension are clinical factors that may lead to a higher propensity for dissection or rupture of ascending thoracic aortic aneurysms (ATAAs). This study sought to investigate effect of valve morphology on regional delamination strength of ATAAs in the elderly hypertensive patients. Whole fresh ATAA samples were harvested from 23 hypertensive patients (age, 71 ± 8 years) who underwent elective aortic surgery. Peeling tests were performed to measure region-specific delamination strengths of the ATAAs, which were compared between patients with bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV). The regional delamination strengths of the ATAAs were further correlated with patient ages and aortic diameters for BAV and TAV groups. In the anterior and right lateral regions, the longitudinal delamination strengths of the ATAAs were statistically significantly higher for BAV patients than TAV patients (33 ± 7 vs. 23 ± 8 mN/mm, <em>p</em> = 0.01; 30 ± 7 vs. 19 ± 9 mN/mm, <em>p</em> = 0.02). For both BAV and TAV patients, the left lateral region exhibited significantly higher delamination strengths in both directions than the right lateral region. Histology revealed that disruption of elastic fibers in the right lateral region of the ATAAs was more severe for the TAV patients than the BAV patients. A strong inverse correlation between longitudinal delamination strength and age was identified in the right lateral region of the ATAAs of the TAV patients. Results suggest that TAV-ATAAs are more vulnerable to aortic dissection than BAV-ATAAs for the elderly hypertensive patients. Regardless of valve morphotypes, the right lateral region may be a special quadrant which is more likely to initiate dissection when compared with other regions.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140180627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving ultrasound-based bone registration using the iterative closest point algorithm paired with a complex optimization solver 使用迭代最邻近点算法和复杂优化求解器改进基于超声波的骨骼配准

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-18 DOI: 10.1016/j.medengphy.2024.104153

Ilias Theodorakos, Michael Skipper Andersen

{"title":"Improving ultrasound-based bone registration using the iterative closest point algorithm paired with a complex optimization solver","authors":"Ilias Theodorakos, Michael Skipper Andersen","doi":"10.1016/j.medengphy.2024.104153","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104153","url":null,"abstract":"<div><p>The Iterative Close Point (ICP) algorithm is used for bone registrations based on ultrasound measurements. However, the ICP has been shown to suffer from local minima. The Complex optimization, as a more robust routine compared to the commonly used gradient-based algorithms, could be an alternative for solving the ICP problem. In this study, we investigated the effect of the initial estimate and the number of registration points on bone registrations achieved using the ICP and a Complex optimization routine and we compared it against using Quadratic Sequential Programming (SQP). Ultrasound measurements were performed with an A-mode probe on a bovine humerus and an ovine femur embedded into ballistic gel. Simultaneously, the bones and the probe were tracked in 3D space using retroreflective markers. Kinematic, ultrasound and geometrical data obtained from scans of the specimens and the probe served as input to a bone registrations routine. Registrations were performed using two ICP solvers for different initial estimates and number of registration points. On average, 68 % of the Complex optimization registrations had less than 1 mm translation error and less than 1° rotational error for perturbations of the initial estimate from the reference measurements compared to the 35 % of the SQP ones. Similar medians of registration errors were observed between the two methods for variations of the number of the employed registration points. Although the Complex optimization provided accurate bone registrations for all cases, the objective function could not always determine the registrations with the smallest registration error. Future research should explore methodologies to overcome this challenge.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1350453324000547/pdfft?md5=d9b5faeb7e6ddfe440305c1550e4e9b8&pid=1-s2.0-S1350453324000547-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140187812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predicting the effects of surgically determined parameters on exercise tolerance in Fontan patients 预测手术参数对丰坦患者运动耐量的影响

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-15 DOI: 10.1016/j.medengphy.2024.104152

Poom Kritpracha , Beatrice Riviere , Charles Puelz

引用次数: 0

Ankle and hindfoot motion of healthy adults during running revealed by dynamic biplane radiography: Side-to-side symmetry, sex-specific differences, and comparison with walking 动态双平面放射摄影显示健康成年人跑步时的踝关节和后足运动：两侧对称性、性别差异以及与步行的比较

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-12 DOI: 10.1016/j.medengphy.2024.104151

Joshua C. Setliff , Paige F. Paulus , Tetsuya Yamamoto , Shumeng Yang , MaCalus V. Hogan , William J. Anderst

{"title":"Ankle and hindfoot motion of healthy adults during running revealed by dynamic biplane radiography: Side-to-side symmetry, sex-specific differences, and comparison with walking","authors":"Joshua C. Setliff , Paige F. Paulus , Tetsuya Yamamoto , Shumeng Yang , MaCalus V. Hogan , William J. Anderst","doi":"10.1016/j.medengphy.2024.104151","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104151","url":null,"abstract":"<div><p>This study aimed to characterize ankle and hindfoot kinematics of healthy men and women during overground running using biplane radiography, and to compare these data to those previously obtained in the same cohort during overground walking. Participants ran across an elevated platform at a self-selected pace while synchronized biplane radiographs of their ankle and hindfoot were acquired. Motion of the tibia, talus, and calcaneus was tracked using a validated volumetric model-based tracking process. Tibiotalar and subtalar 6DOF kinematics were obtained. Absolute side-to-side differences in ROM and kinematics waveforms were calculated. Side-to-side and sex-specific differences were evaluated at 10 % increments of stance phase with mixed model analysis. Pearson correlation coefficients were used to assess the relationship between stance-phase running and walking kinematics. 20 participants comprised the study cohort (10 men, mean age 30.8 ± 6.3 years, mean BMI 24.1 ± 3.1). Average absolute side-to-side differences in running kinematics waveforms were 5.6°/2.0 mm or less at the tibiotalar joint and 5.2°/3.2 mm or less at the subtalar joint. No differences in running kinematics waveforms between sides or between men and women were detected. Correlations were stronger at the tibiotalar joint (42/66 [64 %] of correlations were <em>p</em> < 0.05), than at the tibiotalar joint (38/66 [58 %] of correlations were <em>p</em> < 0.05). These results provide a normative reference for evaluating native ankle and hindfoot kinematics which may be informative in surgical or rehabilitation contexts. Sex-specific differences in ankle kinematics during overground running are likely not clinically or etiologically significant. Associations seen between walking and running kinematics suggest one could be used to predict the other.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140187813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustained release gel based on CT image inspection for treatment of diabetes fundus macular lesions 基于 CT 图像检测的缓释凝胶用于治疗糖尿病眼底黄斑病变

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-11 DOI: 10.1016/j.medengphy.2024.104148

Zhu-min Yang, Xing Huang, Sheng-hui Liu, Li-shi Deng, Xian Wang

{"title":"Sustained release gel based on CT image inspection for treatment of diabetes fundus macular lesions","authors":"Zhu-min Yang, Xing Huang, Sheng-hui Liu, Li-shi Deng, Xian Wang","doi":"10.1016/j.medengphy.2024.104148","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104148","url":null,"abstract":"<div><p>Currently, slow-release gel therapy is considered to be an effective treatment for fundus macular disease, but the lack of effective evaluation methods limits its clinical application. Therefore, the purpose of this study was to investigate the application and clinical effect of slow-release gel based on CT image examination in the treatment of diabetic fundus macular disease. CT images of fundus macular lesions were collected in a group of diabetic patients. Then the professional image processing software is used to process and analyze the image and extract the key parameters. A slow-release gel was designed and prepared, and applied to the treatment of diabetic fundus macular disease. CT images before and after treatment were compared and analyzed, and the effect of slow-release gel was evaluated. In a certain period of time after treatment, the lesion size and lesion degree of diabetic fundus macular disease were significantly improved by using slow-release gel therapy with CT image examination. No significant adverse reactions or complications were observed during the treatment. This indicates that the slow-release gel based on CT image examination is a safe, effective and feasible treatment method for diabetic fundus macular disease. This method can help improve the vision and quality of life of patients, and provide a new idea and plan for clinical treatment.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140122362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validity and reliability of inertial measurement units used to measure motion of the lumbar spine: A systematic review of individuals with and without low back pain 用于测量腰椎运动的惯性测量装置的有效性和可靠性：对腰痛患者和无腰痛患者的系统回顾

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-11 DOI: 10.1016/j.medengphy.2024.104146

Frederick A. McClintock, Andrew J. Callaway, Carol J. Clark, Jonathan M. Williams

{"title":"Validity and reliability of inertial measurement units used to measure motion of the lumbar spine: A systematic review of individuals with and without low back pain","authors":"Frederick A. McClintock, Andrew J. Callaway, Carol J. Clark, Jonathan M. Williams","doi":"10.1016/j.medengphy.2024.104146","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104146","url":null,"abstract":"<div><p>Low back pain (LBP) is a leading cause of disability, resulting in aberrant movement. This movement is difficult to measure accurately in clinical practice and gold standard methods, such as optoelectronic systems involve the use of expensive laboratory equipment. Inertial measurement units (IMU) offer an alternative method of quantifying movement that is accessible in most environments. However, there is no consensus around the validity and reliability of IMUs for quantifying lumbar spine movements compared with gold standard measures. The aim of this systematic review was to establish concurrent validity and repeated measures reliability of using IMUs for the measurement of lumbar spine movements in individuals with and without LBP. A systematic search of electronic databases, incorporating PRISMA guidelines was completed, limited to the English language. 503 studies were identified where 15 studies met the inclusion criteria. Overall, 305 individuals were included, and 109 of these individuals had LBP. Weighted synthesis of the results demonstrated root mean squared differences of <2.4° compared to the gold standard and intraclass correlations >0.84 for lumbar spine movements. IMUs offer clinicians and researchers valid and reliable measurement of motion in the lumbar spine, comparable to laboratory methods, such as optoelectronic motion capture for individuals with and without LBP.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S135045332400047X/pdfft?md5=51b1da48edfdd3b2278ae9c7b7a6d65d&pid=1-s2.0-S135045332400047X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140122363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Virtual and analytical self-expandable braided stent treatment models 虚拟和分析自膨胀编织支架治疗模型

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-11 DOI: 10.1016/j.medengphy.2024.104145

Reza Abdollahi , Amirali Shahi , Daniel Roy , Simon Lessard , Rosaire Mongrain , Gilles Soulez

{"title":"Virtual and analytical self-expandable braided stent treatment models","authors":"Reza Abdollahi , Amirali Shahi , Daniel Roy , Simon Lessard , Rosaire Mongrain , Gilles Soulez","doi":"10.1016/j.medengphy.2024.104145","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104145","url":null,"abstract":"<div><p>The Flow Diverter is a self-expandable braided stent that has helped improve the effectiveness of cerebral aneurysm treatment during the last decade. The Flow Diverter's efficiency heavily relies on proper decision-making during the pre-operative phase, which is currently based on static measurements that fail to account for vessel or tissue deformation. In the context of providing realistic measurements, a biomechanical computational method is designed to aid physicians in predicting patient-specific treatment outcomes. The method integrates virtual and analytical treatment models, validated against experimental mechanical tests, and two patient treatment outcomes. In the case of both patients, deployed stent length was one of the validated result parameters, which displayed an error inferior to 1.5% for the virtual and analytical models. These results indicated both models' accuracy. However, the analytical model provided more accurate results with a 0.3% error while requiring a lower computational cost for length prediction. This computational method can offer designing and testing platforms for predicting possible intervention-related complications, patient-specific medical device designs, and pre-operative planning to automate interventional procedures.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140134857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Image testing based on biomedical drug loading in cardiovascular drug care simulation for coronary heart disease 冠心病心血管药物护理模拟中基于生物医学药物负载的图像测试

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-03-11 DOI: 10.1016/j.medengphy.2024.104150

Guifang Song , Huili Chang , Nv Mu

{"title":"Image testing based on biomedical drug loading in cardiovascular drug care simulation for coronary heart disease","authors":"Guifang Song , Huili Chang , Nv Mu","doi":"10.1016/j.medengphy.2024.104150","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104150","url":null,"abstract":"<div><p>Coronary heart disease is a common cardiovascular disease, and its therapeutic effect is affected by the distribution and absorption of drugs in the body. Biomedical drug-carrying image testing technology can provide a quantitative assessment of drug distribution and absorption in the body. This study aims to explore the application of biomedical drug-carrying image testing technology in the simulation of cardiovascular drug care in coronary heart disease, so as to provide reference for the optimization of drug treatment plan and individualized treatment. The study collected clinical data and medication regiments of patients with coronary heart disease. Then, the imaging examination of patients was carried out by selecting appropriate drug loading markers using the biomedical drug loading image examination technology. Then quantitative analysis was used to process the image data to quantitatively evaluate the distribution and absorption of drugs in the cardiovascular system. The quantitative data of drug distribution and absorption in patients with coronary heart disease have been obtained successfully by means of biomedical imaging. These data reveal the dynamic changes of drugs in the cardiovascular system, and help doctors optimize drug therapy, improve treatment effectiveness, and achieve personalized treatment.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140160180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0