Medical Engineering & Physics最新文献_第9页

Finite element analysis of implanted lumbar spine: Effects of open laminectomy plus PLF and open laminectomy plus TLIF surgical approaches on L3-L4 FSU 植入式腰椎的有限元分析：开放式椎板切除术加 PLF 和开放式椎板切除术加 TLIF 手术方法对 L3-L4 FSU 的影响

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-05-07 DOI: 10.1016/j.medengphy.2024.104178

Kishore Pradeep , Bidyut Pal , Kaushik Mukherjee , Gautam M. Shetty

{"title":"Finite element analysis of implanted lumbar spine: Effects of open laminectomy plus PLF and open laminectomy plus TLIF surgical approaches on L3-L4 FSU","authors":"Kishore Pradeep , Bidyut Pal , Kaushik Mukherjee , Gautam M. Shetty","doi":"10.1016/j.medengphy.2024.104178","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104178","url":null,"abstract":"<div><p>Several finite element (FE) studies reported performances of various lumbar fusion surgical approaches. However, comparative studies on the performance of Open Laminectomy plus Posterolateral Fusion (OL-PLF) and Open Laminectomy plus Transforaminal Interbody Fusion (OL-TLIF) surgical approaches are rare. In the current FE study, the variation in ranges of motions (ROM), stress-strain distributions in an implanted functional spinal unit (FSU) and caudal adjacent soft structures between OL-PLF and OL-TLIF virtual models were investigated. The implanted lumbar spine FE models were developed from subject-specific computed tomography images of an intact spine and solved for physiological loadings such as compression, flexion, extension and lateral bending. Reductions in the ROMs of L1-L5 (49 % to 59 %) and L3-L4 implanted FSUs (91 % to 96 %) were observed for both models. Under all the loading cases, the maximum von Mises strain observed in the implanted segment of both models exceeds the mean compressive yield strain for the vertebra. The maximum von Mises stress and strain observed on the caudal adjacent soft structures of both the implanted models are at least 22 % higher than the natural spine model. The findings indicate the risk of failure in the implanted FSUs and higher chances of adjacent segment degeneration for both models.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"128 ","pages":"Article 104178"},"PeriodicalIF":2.2,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140909892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dosimetric benefits and preclinical performance of steerable needles in HDR prostate brachytherapy 可转向针在 HDR 前列腺近距离放射治疗中的剂量学优势和临床前性能

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-05-07 DOI: 10.1016/j.medengphy.2024.104177

M. de Vries , M.E.M.C. Christianen , L. Luthart , K.C. de Vries , I.K.K. Kolkman-Deurloo , J.J. van den Dobbelsteen

{"title":"Dosimetric benefits and preclinical performance of steerable needles in HDR prostate brachytherapy","authors":"M. de Vries , M.E.M.C. Christianen , L. Luthart , K.C. de Vries , I.K.K. Kolkman-Deurloo , J.J. van den Dobbelsteen","doi":"10.1016/j.medengphy.2024.104177","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104177","url":null,"abstract":"<div><p>Prostate cancer patients with an enlarged prostate and/or excessive pubic arch interference (PAI) are generally considered non-eligible for high-dose-rate (HDR) brachytherapy (BT). Steerable needles have been developed to make these patients eligible again. This study aims to validate the dosimetric impact and performance of steerable needles within the conventional clinical setting.</p><p>HDR BT treatment plans were generated, needle implantations were performed in a prostate phantom, with prostate volume > 55 cm<sup>3</sup> and excessive PAI of 10 mm, and pre- and post-implant dosimetry were compared considering the dosimetric constraints: prostate V<sub>100</sub> > 95 % (13.50 Gy), urethra D<sub>0.1cm</sub><sup>3</sup> < 115 % (15.53 Gy) and rectum D<sub>1cm</sub><sup>3</sup> < 75 % (10.13 Gy).</p><p>The inclusion of steerable needles resulted in a notable enhancement of the dose distribution and prostate V<sub>100</sub> compared to treatment plans exclusively employing rigid needles to address PAI. Furthermore, the steerable needle plan demonstrated better agreement between pre- and post-implant dosimetry (prostate V<sub>100</sub>: 96.24 % vs. 93.74 %) compared to the rigid needle plans (79.13 % vs. 72.86 % and 87.70 % vs. 81.76 %), with no major changes in the clinical workflow and no changes in the clinical set-up.</p><p>The steerable needle approach allows for more flexibility in needle positioning, ensuring a highly conformal dose distribution, and hence, HDR BT is a feasible treatment option again for prostate cancer patients with an enlarged prostate and/or excessive PAI.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"128 ","pages":"Article 104177"},"PeriodicalIF":2.2,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S135045332400078X/pdfft?md5=ba76818e3a49cfd1abb83c86f3ee3956&pid=1-s2.0-S135045332400078X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection of scapholunate interosseous ligament injury using dynamic computed tomography-derived arthrokinematics: A prospective clinical trial 利用动态计算机断层扫描衍生关节运动学检测肩胛骨骨间韧带损伤：前瞻性临床试验

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-04-27 DOI: 10.1016/j.medengphy.2024.104172

Taylor P. Trentadue , Andrew R. Thoreson , Cesar Lopez , Ryan E. Breighner , Kai-Nan An , David R. Holmes III , Steven L. Moran , Sanjeev Kakar , Naveen S. Murthy , Shuai Leng , Kristin D. Zhao

{"title":"Detection of scapholunate interosseous ligament injury using dynamic computed tomography-derived arthrokinematics: A prospective clinical trial","authors":"Taylor P. Trentadue , Andrew R. Thoreson , Cesar Lopez , Ryan E. Breighner , Kai-Nan An , David R. Holmes III , Steven L. Moran , Sanjeev Kakar , Naveen S. Murthy , Shuai Leng , Kristin D. Zhao","doi":"10.1016/j.medengphy.2024.104172","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104172","url":null,"abstract":"<div><p>Scapholunate interosseous ligament injuries are a major cause of wrist instability and can be difficult to diagnose radiographically. To improve early diagnosis of scapholunate ligament injuries, we compared injury detection between bilateral routine clinical radiographs, static CT, and dynamic four-dimensional CT (4DCT) during wrist flexion-extension and radioulnar deviation. Participants with unilateral scapholunate ligament injuries were recruited to a prospective clinical trial investigating the diagnostic utility of 4DCT imaging for ligamentous wrist injury. Twenty-one participants underwent arthroscopic surgery to confirm scapholunate ligament injury. Arthrokinematics, defined as distributions of interosseous proximities across radioscaphoid and scapholunate articular surfaces at different positions within the motion cycle, were used as CT-derived biomarkers. Preoperative radiographs, static CT, and extrema of 4DCT were compared between uninjured and injured wrists using Wilcoxon signed rank or Kolmogorov-Smirnov tests. Median interosseous proximities at the scapholunate interval were significantly greater in the injured versus the uninjured wrists at static-neutral and maximum flexion, extension, radial deviation, and ulnar deviation. Mean cumulative distribution functions at the radioscaphoid joint were not significantly different between wrists but were significantly shifted at the scapholunate interval towards increased interosseous proximities in injured versus uninjured wrists in all positions. Median and cumulative distribution scapholunate proximities from static-neutral and 4DCT-derived extrema reflect injury status.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"128 ","pages":"Article 104172"},"PeriodicalIF":2.2,"publicationDate":"2024-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140901546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Digital design and fabrication of multi-material hand orthoses to allow an athlete with scleroderma to play sitting volleyball 数字化设计和制造多材料手部矫形器，使硬皮病运动员能够进行坐式排球比赛

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-04-26 DOI: 10.1016/j.medengphy.2024.104174

Andrea Giovanni Cutti , Maria Grazia Santi , Francesca Gariboldi , Raffaele Terribile , Laura Petrucci , Nicola Petrone , Gregorio Teti

{"title":"Digital design and fabrication of multi-material hand orthoses to allow an athlete with scleroderma to play sitting volleyball","authors":"Andrea Giovanni Cutti , Maria Grazia Santi , Francesca Gariboldi , Raffaele Terribile , Laura Petrucci , Nicola Petrone , Gregorio Teti","doi":"10.1016/j.medengphy.2024.104174","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104174","url":null,"abstract":"<div><p>Scleroderma is a chronic and progressive autoimmune disorder of connective tissues often causing lesions and deformities of the hands. Individuals affected by this condition experience daily life limitations and are typically unable to take part in sport activities that involve impacts on the hands. In this article we describe the design and manufacturing of custom-made hand orthoses to play sitting volleyball, for an elite paralympic athlete affected by scleroderma. The devices consist of a carbon fibre shell with an internal silicone padding and an external polymeric multilayer cover. The manufacturing of the orthoses involves digital modelling, 3D printing, composite lamination and an innovative method to create a strong and durable chemical bonding between silicone and carbon fibre. The internal silicone padding proved to be effective in hosting and protecting the hands, whereas the external shell with polymeric multilayer cover allowed to dampen the ball shocks while effectively hitting the ball. Indeed, these devices allowed the athlete to take part in the 2020 Tokyo Paralympic games and were used for two years without showing any damage.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"128 ","pages":"Article 104174"},"PeriodicalIF":2.2,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1350453324000754/pdfft?md5=9bb59cbf84b4679f79a95493140d6ee9&pid=1-s2.0-S1350453324000754-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140824691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computational fluid dynamics analysis of the fluid environment of 3D printed gradient structure in interfacial tissue engineering 界面组织工程中三维打印梯度结构的流体环境计算流体动力学分析

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-04-26 DOI: 10.1016/j.medengphy.2024.104173

Bin Zhang

{"title":"Computational fluid dynamics analysis of the fluid environment of 3D printed gradient structure in interfacial tissue engineering","authors":"Bin Zhang","doi":"10.1016/j.medengphy.2024.104173","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104173","url":null,"abstract":"<div><p>Mass transport properties within three-dimensional (3D) scaffold are essential for tissue regeneration, such as various fluid environmental cues influence mesenchymal stem cells differentiation. Recently, 3D printing has been emerging as a new technology for scaffold fabrication by controlling the scaffold pore geometry to affect cell growth environment. In this study, the flow field within scaffolds in a perfusion system was investigated with uniform structures, single gradient structures and complex gradient structures using computational fluid dynamics (CFD) method. The CFD results from those uniform structures indicate the fluid velocity and fluid shear stress within the scaffold structure increased as the filament diameter increasing, pore width decreasing, pore shape decreased from 90° to 15°, and layer configuration changing from lattice to stagger structure. By assembling those uniform structure as single gradient structures, it is noted that the fluid dynamic characterisation within the scaffold remains the same as the corresponding uniform structures. A complex gradient structure was designed to mimic natural osteochondral tissue by assembly the uniform structures of filament diameter, pore width, pore shape and layer configuration. The results show that the fluid velocity and fluid shear stress within the complex gradient structure distribute gradually increasing and their maximum magnitude were from 1.15 to 3.20 mm/s, and from 12 to 39 mPa, respectively. CFD technique allows the prediction of velocity and fluid shear stress within the designed 3D gradient scaffolds, which would be beneficial for the tissue scaffold development for interfacial tissue engineering in the future.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"128 ","pages":"Article 104173"},"PeriodicalIF":2.2,"publicationDate":"2024-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1350453324000742/pdfft?md5=9c078d7de1bc998ac1149ffe7f817b96&pid=1-s2.0-S1350453324000742-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140824690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ATST-Net: A method to identify early symptoms in the upper and lower extremities of PD ATST-Net：识别帕金森病上下肢早期症状的方法

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-04-19 DOI: 10.1016/j.medengphy.2024.104171

Yuanyuan Liu , Zhaoyi Yang , Miao Cai , Yanwen Wang , Xiaoli Liu , Hexing Tong , Yuhang Peng , Yue Lou , Zhu Li

{"title":"ATST-Net: A method to identify early symptoms in the upper and lower extremities of PD","authors":"Yuanyuan Liu , Zhaoyi Yang , Miao Cai , Yanwen Wang , Xiaoli Liu , Hexing Tong , Yuhang Peng , Yue Lou , Zhu Li","doi":"10.1016/j.medengphy.2024.104171","DOIUrl":"10.1016/j.medengphy.2024.104171","url":null,"abstract":"<div><p>Bradykinesia, a core symptom of motor disorders in Parkinson's disease (PD), is a major criterion for screening early PD patients in clinical practice. Currently, many studies have proposed automatic assessment schemes for bradykinesia in PD. However, existing schemes suffer from problems such as dependence on professional equipment, single evaluation tasks, difficulty in obtaining samples and low accuracy. This paper proposes a manual feature extraction- and neural network-based method to evaluate bradykinesia, effectively solving the problem of a small sample size. This method can automatically assess finger tapping (FT), hand movement (HM), toe tapping (TT) and bilateral foot sensitivity tasks (LA) through a unified model. Data were obtained from 120 individuals, including 93 patients with Parkinson's disease and 27 age- and sex-matched normal controls (NCs). Manual feature extraction and Attention Time Series Two-stream Networks (ATST-Net) were used for classification. Accuracy rates of 0.844, 0.819, 0.728, and 0.768 were achieved for FT, HM, TT, and LA, respectively. To our knowledge, this study is the first to simultaneously evaluate the upper and lower limbs using a unified model that has significant advantages in both model training and transfer learning.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"128 ","pages":"Article 104171"},"PeriodicalIF":2.2,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140795159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of different fixation systems on oblique lumbar interbody fusion under vibration conditions 不同固定系统对振动条件下斜腰椎椎间融合术的影响

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-04-16 DOI: 10.1016/j.medengphy.2024.104169

Bin Zhang , Tian-Cheng Li , Xin Wang , Cheng-Fei Du , Rui Zhu

{"title":"The effect of different fixation systems on oblique lumbar interbody fusion under vibration conditions","authors":"Bin Zhang , Tian-Cheng Li , Xin Wang , Cheng-Fei Du , Rui Zhu","doi":"10.1016/j.medengphy.2024.104169","DOIUrl":"10.1016/j.medengphy.2024.104169","url":null,"abstract":"<div><p>Despite the fact that lower back pain caused by degenerative lumbar spine pathologies seriously affects the quality of life, however, there is a paucity of research on the biomechanical properties of different auxiliary fixation systems for its primary treatment (oblique lumbar interbody fusion) under vibratory environments. In order to study the effects of different fixation systems of OLIF surgery on the vibration characteristics of the human lumbar spine under whole-body vibration (WBV), a finite element (FE) model of OLIF surgery with five different fixation systems was established by modifying a previously established model of the normal lumbar spine (L1–S1). In this study, a compressive follower load of 500 N and a sinusoidal axial vertical load of ±40 N at the frequency of 5 Hz with a duration of 0.6 s was applied. The results showed that the bilateral pedicle screw fixation model had the highest resistance to cage subsidence and maintenance of disc height under WBV. In contrast, the lateral plate fixation model exerted very high stresses on important tissues, which would be detrimental to the patient's late recovery and reduction of complications. Therefore, this study suggests that drivers and related practitioners who are often in vibrating environments should have bilateral pedicle screws for OLIF surgery, and side plates are not recommended to be used as a separate immobilization system. Additionally, the lateral plate is not recommended to be used as a separate fixation system.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"128 ","pages":"Article 104169"},"PeriodicalIF":2.2,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140764654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative Capillary Refill Time with image-based finger force estimation 利用基于图像的指力估算定量毛细血管再充盈时间

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-04-16 DOI: 10.1016/j.medengphy.2024.104168

Takumi Nagasawa , Kazuki Iwata , Raquel Pantojo de Souza Bachour , Keiko Ogawa-Ochiai , Norimichi Tsumura , George C. Cardoso

引用次数: 0

Comparison of LED- and LASER-based fNIRS technologies to record the human peri‑spinal cord neurovascular response 基于 LED 和激光的 fNIRS 技术在记录人体脊髓周围神经血管反应方面的比较

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-04-12 DOI: 10.1016/j.medengphy.2024.104170

Raúl Caulier-Cisterna , Juan-Pablo Appelgren-Gonzáles , Juan-Esteban Oyarzún , Felipe Valenzuela , Ranganatha Sitaram , Antonio Eblen-Zajjur , Sergio Uribe

{"title":"Comparison of LED- and LASER-based fNIRS technologies to record the human peri‑spinal cord neurovascular response","authors":"Raúl Caulier-Cisterna , Juan-Pablo Appelgren-Gonzáles , Juan-Esteban Oyarzún , Felipe Valenzuela , Ranganatha Sitaram , Antonio Eblen-Zajjur , Sergio Uribe","doi":"10.1016/j.medengphy.2024.104170","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104170","url":null,"abstract":"<div><p>Recently, functional Near-Infrared Spectroscopy (fNIRS) was applied to obtain, non-invasively, the human peri‑spinal Neuro-Vascular Response (NVR) under a non-noxious electrical stimulation of a peripheral nerve. This method allowed the measurements of changes in the concentration of oxyhemoglobin (<em>O<sub>2</sub>Hb</em>) and deoxyhemoglobin (<em>HHb</em>) from the peri‑spinal vascular network. However, there is a lack of clarity about the potential differences in perispinal NVR recorded by the different fNIRS technologies currently available. In this work, the two main noninvasive fNIRS technologies were compared, i.e., LED and LASER-based. The recording of the human peri‑spinal NVR induced by non-noxious electrical stimulation of a peripheral nerve was recorded simultaneously at <em>C</em><sub>7</sub> and <em>T</em><sub>10</sub> vertebral levels. The amplitude, rise time, and full width at half maximum duration of the perispinal NVRs were characterized in healthy volunteers and compared between both systems. The main difference was that the LED-based system shows about one order of magnitude higher values of amplitude than the LASER-based system. No statistical differences were found for rise time and for duration parameters (at thoracic level). The comparison of point-to-point wave patterns did not show significant differences between both systems. In conclusion, the peri‑spinal NRV response obtained by different fNIRS technologies was reproducible, and only the amplitude showed differences, probably due to the power of the system which should be considered when assessing the human peri‑spinal vascular network.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"127 ","pages":"Article 104170"},"PeriodicalIF":2.2,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1350453324000717/pdfft?md5=c341f41b79959fce9d5cf94637c06878&pid=1-s2.0-S1350453324000717-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140631712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modeling and experimental study of the intervention forces between the guidewire and blood vessels 导丝与血管间介入力的建模和实验研究

IF 2.2 4区医学

Medical Engineering & Physics Pub Date : 2024-04-11 DOI: 10.1016/j.medengphy.2024.104166

Pan Li , Jing Feng , Xue Zhang , Delei Fang , Junxia Zhang , Cunman Liang

{"title":"Modeling and experimental study of the intervention forces between the guidewire and blood vessels","authors":"Pan Li , Jing Feng , Xue Zhang , Delei Fang , Junxia Zhang , Cunman Liang","doi":"10.1016/j.medengphy.2024.104166","DOIUrl":"https://doi.org/10.1016/j.medengphy.2024.104166","url":null,"abstract":"<div><p>A profound investigation of the interaction mechanics between blood vessels and guidewires is necessary to achieve safe intervention. An interactive force model between guidewires and blood vessels is established based on cardiovascular fluid dynamics theory and contact mechanics, considering two intervention phases (straight intervention and contact intervention at a corner named “J-vessel”). The contributing factors of the force model, including intervention conditions, guidewire characteristics, and intravascular environment, are analyzed. A series of experiments were performed to validate the availability of the interactive force model and explore the effects of influential factors on intervention force. The intervention force data were collected using a 2-DOF mechanical testing system instrumented with a force sensor. The guidewire diameter and material were found to significantly impact the intervention force. Additionally, the intervention force was influenced by factors such as blood viscosity, blood vessel wall thickness, blood flow velocity, as well as the interventional velocity and interventional mode. The experiment of the intervention in a coronary artery physical vascular model confirms the practicality validation of the predicted force model and can provide an optimized interventional strategy for vascular interventional surgery. The enhanced intervention strategy has resulted in a considerable reduction of approximately 21.97 % in the force exerted on blood vessels, effectively minimizing the potential for complications associated with the interventional surgery.</p></div>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"127 ","pages":"Article 104166"},"PeriodicalIF":2.2,"publicationDate":"2024-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140619404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0