Medical Engineering & Physics最新文献

{"title":"Optical hand kinematics for machine learning-based screening of carpal tunnel syndrome.","authors":"Şerife Çelikbaş, Abdurrahim Akgündoğdu, Ayşegül Gündüz","doi":"10.1088/1873-4030/ae8dce","DOIUrl":"10.1088/1873-4030/ae8dce","url":null,"abstract":"<p><p>Carpal tunnel syndrome is usually assessed by clinical examination and electrodiagnostic testing, but these methods may not always be practical for rapid screening. In this work, it was explored whether hand motion recorded with a low-cost optical camera could add useful information to routine clinical data. Demographic variables, symptom-related findings obtained after the Phalen test, and five thumb-to-finger opposition tasks were collected. Hand landmarks were extracted with MediaPipe and used to derive kinematic descriptors, which were then analyzed together with clinical variables by machine-learning and hybrid deep-learning models. To reduce the risk of overly optimistic estimates, the main evaluation was carried out at hand level with leave-one-group-out cross-validation. In the primary leakage-safe comparison, the best Dataset 4 multimodal model yielded the strongest binary screening profile. Compared with the clinical Dataset 1 baseline, accuracy increased from 82.6% (95% CI 75.0%-90.2%) to 87.0% (79.3%-93.5%), sensitivity from 70.0% (54.4%-85.1%) to 80.0% (64.7%-93.4%), specificity from 88.7% (80.3%-95.6%) to 90.3% (83.1%-96.8%), and ROC-AUC from 0.845 (0.745-0.934) to 0.855 (0.752-0.945). In the same-architecture tests, the kinematic variables did not behave uniformly across model families. The clearest gain among the classical models was seen with light gradient boosting machine. Feature-level results were also consistent with the model findings, as selected thumb-opposition coordinates differed across stages and appeared to capture a functional component not represented by symptom scores. In the four-class severity task, the improvement was small: accuracy increased from 81.5% (72.8%-89.1%) to 82.6% (73.9%-90.2%), and macro-1 increased from 0.706 (0.544-0.823) to 0.748 (0.588-0.850). In this cohort, the optical hand-kinematic measures mainly strengthened the screening analysis. Their use for finer severity staging will need confirmation in larger external datasets and in participant-level analyses.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148551249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MultiReGAME, a gamified multimodal station for rehabilitation: pilot study.","authors":"Juan J Sánchez-Gil, Aurora Sáez, Juan José Ochoa-Sepúlveda, Rafael López-Luque, Eduardo Cañete-Carmona","doi":"10.1088/1873-4030/ae8bb1","DOIUrl":"10.1088/1873-4030/ae8bb1","url":null,"abstract":"<p><p>Accessible rehabilitation technologies that combine motor and cognitive training can expand treatment options for people with neurological disorders. The aim of this study was to design and conduct a pilot evaluation of MultiReGAME, a compact, non-invasive, gamified multimodal rehabilitation system with multiple sensing modalities for training the upper and lower limbs, hands, wrists, and cognitive functions. The platform integrates adjustable force-threshold interaction, vertical displacement-based game control, joystick and button controls, tactile interaction, keyboard input, and visual and haptic feedback. Thirteen serious games with multiple difficulty levels and input options (including multiplayer modes) were developed to facilitate personalized training, and automatic post-session summaries were included for remote follow-up of session-level performance and adherence-related variables. A single-session pilot study was conducted with 25 participants, including healthy adults and adults with neurological conditions (Córdoba, Spain). Usability and user experience were assessed following standardized exposure to the platform. Both groups successfully completed the session, reporting high perceived usability and a generally positive user experience, particularly regarding stimulation, engagement, and novelty. No fatigue or device-related adverse events were observed. These findings support the preliminary feasibility of MultiReGAME for supervised rehabilitation with remote monitoring, although further studies are needed to assess long-term reliability, adherence, and clinical efficacy. Sensor-derived force and displacement signals were not used as clinical outcomes in this pilot study.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of a smartphone-based inertial measurement approach for quantitative gait analysis.","authors":"Fatma Nur Altin, Gracian Trivino, Erdoğan Kavlak","doi":"10.1088/1873-4030/ae8c43","DOIUrl":"10.1088/1873-4030/ae8c43","url":null,"abstract":"<p><p>Quantitative gait analysis is an important tool in clinical assessment and biomechanical research. Vision-based motion capture systems used in dedicated gait laboratories are considered the reference standard, providing highly accurate kinematic measurements, but they require specialized infrastructure and controlled environments. As a result, wearable inertial sensor systems have become a practical alternative for clinical and everyday gait assessment. This study presents a comparative evaluation of a smartphone-based gait analysis method and a clinically established wearable inertial system. Gait recordings representing healthy, mildly asymmetric, and impaired walking patterns were analysed using both approaches. The comparison focused on clinically relevant parameters, including cadence, swing-phase duration symmetry, and vertical acceleration symmetry. The smartphone-based method employs median-based statistics and robust outlier rejection to enhance reliability under non-ideal measurement conditions. For healthy and mildly asymmetric gait, both systems produced comparable parameter estimates. In gait patterns with pronounced imbalance, the smartphone-based method detected larger deviations, indicating enhanced sensitivity to asymmetry and pathological alterations, highlighting the benefits of robust statistical modelling when gait data deviate from Gaussian distributions. These findings demonstrate a strong level of agreement between the proposed smartphone-based method and a clinically established wearable inertial system while supporting the practical applicability and robustness of the approach for quantitative gait assessment. The method provides gait parameters comparable to those obtained with a wearable reference system while maintaining stable performance across different walking conditions. Its low instrumentation requirements and applicability outside laboratory settings make it suitable for rehabilitation follow-up, fall risk assessment, and repeated gait evaluation over time.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A computational fluid dynamics investigation of blood shear stress and shear-induced platelet activation in rotational atherectomy.","authors":"Yuwen Liang, Urara Satake, Toshiyuki Enomoto","doi":"10.1088/1873-4030/ae8c42","DOIUrl":"10.1088/1873-4030/ae8c42","url":null,"abstract":"<p><p>Rotational atherectomy (RA) is widely used for lesion preparation in severely calcified coronary lesions; however, shear-induced platelet activation associated with high-speed rotating burr may contribute to complications such as slow-flow and no-reflow. Therefore, clarifying the distribution and mechanisms of high-shear regions in blood and identifying the dominant regions responsible for shear-induced platelet activation, are important for improving RA procedures. However, these issues have received limited attention in previous studies on RA. In this study, a three-dimensional computational fluid dynamics model with Lagrangian particle tracking was used to investigate high-shear regions and the regions dominantly contributing to shear-induced platelet activation during RA. The effects of rotational speed, lumen diameter, and burr diameter on shear stress and platelet activation potential were examined. The results show that high-shear regions mainly form at the radial jet originating near the burr equator, in the flow adjacent to the vessel wall after radial jet impinges on the wall, and in the narrow high-velocity regions near the rotating surfaces of shaft and burr. Platelet activation potential was dominated by the burr segment, mainly due to the high-shear region near the burr surface and, to a lesser extent, the high-shear region associated with the radial jet. Higher rotational speed, smaller lumen diameter, and larger burr diameter increased platelet activation potential by increasing shear stress and exposing more blood flow to high-shear regions. These findings provide mechanistic insights into high-shear regions and shear-induced platelet activation during RA and may help guide further procedural improvements to reduce periprocedural complications.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatiotemporal dynamics of blood coagulation in medium-sized vessels: numerical insights into the effects of vessel walls and blood flow.","authors":"Ken-Ichi Tsubota, Tsutomu Tajikawa","doi":"10.1088/1873-4030/ae85fe","DOIUrl":"https://doi.org/10.1088/1873-4030/ae85fe","url":null,"abstract":"<p><p>The spatiotemporal distribution of coagulation factors fundamentally governs blood coagulation dynamics. Although these dynamics have been examined at the submillimeter scale (hundred micrometers), how this distribution influences thrombus formation at dimensions comparable to or larger than those of medium-sized vessels (on the order of 1 mm in diameter) remains insufficiently clarified. In this study, we performed numerical simulations using a well-established reaction-diffusion model of the intrinsic coagulation pathway to investigate coagulation kinetics over millimeter-scale domains, while explicitly incorporating the effects of walls and convection on coagulation. The simulation settings were validated against experimentally observed coagulation behaviors. Our results indicated that in blood domains adjacent to an active wall surface, the propagation velocities of the thrombin wave and the advancing clot front decreased with increasing distance from the wall and approached a constant value at approximately 200<i>µ</i>m. This spatial variation in velocity led to domain-size-dependent behavior in the temporal evolution of the volume-averaged thrombin concentration in millimeter-scale domains analyzed in thrombin generation assays because the domain size determined the ratio of the active surface area to blood volume. In addition, simulations of coagulation along a 5 cm-long thin filament within a rat arteriovenous shunt showed a progressive increase in the coagulation rate along the flow direction, indicating that the longitudinal distribution of coagulation activity governs the total clot volume. Together, these findings underscore the need to resolve multiscale spatial distributions of coagulation, from the micrometer to centimeter scales, to improve understanding of thrombus formation under physiological conditions where the effects of walls and convection interact.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"147 7","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary validation of a portable, radiation-free, surface-based system (OmÖS) for sagittal spinal curvature measurement.","authors":"Osman Uzun, Ramazan Kayacan, Halil Burç","doi":"10.1088/1873-4030/ae8a54","DOIUrl":"10.1088/1873-4030/ae8a54","url":null,"abstract":"<p><p>Radiographic assessment remains the reference standard for measuring sagittal spinal curvatures; however, repeated exposure to ionizing radiation limits its suitability for screening and longitudinal follow-up. This has motivated the development of reliable, radiation-free measurement technologies capable of providing clinically meaningful curvature estimates. This study presents the preliminary validation of a portable, radiation-free, surface-based measurement system (OmÖS) designed for sagittal plane spinal curvature measurement. Thoracic and lumbar curvature angles were measured in 16 volunteers using both lateral spinal radiographs (radiographic Cobb method, RaG) and OmÖS under standardized standing conditions. Curvature angles were calculated using surface-based geometrical parameters derived from palpated spinous process locations. System performance was evaluated through internal calibration by comparing stepper motor-based and linear variable differential transformer (LVDT)-based measurements; validity and agreement analyses against radiographic measurements using Pearson correlation, Bland-Altman analysis, and simple linear regression, as well as test-retest reliability assessment over a two-week interval using intraclass correlation coefficients (ICCs). OmÖS demonstrated a very strong correlation with radiographic measurements for thoracic curvature angles (<i>r</i>= 0.974,<i>p</i>< 0.001) and a strong correlation for lumbar curvature angles (<i>r</i>= 0.852,<i>p</i>< 0.001). Bland-Altman analysis indicated minimal systematic bias for thoracic curvature measurements (0.13°), with limits of agreement within predefined clinically acceptable ranges. For lumbar curvature angles, agreement was characterized by slightly wider limits of agreement, but without evidence of systematic bias. Internal calibration demonstrated excellent agreement between the mechanical and electronic measurement components (<i>r</i>> 0.99). Test-retest reliability analysis demonstrated excellent reproducibility for both regions (ICC = 0.990), with low standard error of measurement (SEM = 0.61°) and minimum detectable change at the 95% confidence level (MDC95 = 1.70°). These findings indicate that OmÖS can provide reliable and reproducible radiation-free measurements of sagittal spinal curvature angles under standardized conditions. Whether the proposed system represents a radiation-free alternative of sagittal spinal curvature assessment for screening needs to be confirmed in future clinical studies involving larger and more diverse populations.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A high-performance, memory efficient micro-FE solver for large scale heterogeneous image-based models on consumer hardware.","authors":"Adam Gorski, O Remus Tutunea-Fatan, Louis M Ferreira, Nikolas K Knowles","doi":"10.1088/1873-4030/ae8a53","DOIUrl":"10.1088/1873-4030/ae8a53","url":null,"abstract":"<p><p>Micro finite element modeling is commonly used in bone research to predict strains, stresses, forces and displacements. To accurately capture the underlying bone microstructure, microCT can be used to generate large scale heterogeneous image-based models. However, these large models quickly overwhelm traditional solvers, even when efficiently optimized sparse matrices are used. Matrix-free methods can be combined with preconditioned conjugate gradient (PCG) methods to further decrease memory usage, however, the unstructured solvers required for porous bone still require significant amounts of memory for the mesh. Additionally, typical FE solvers designed for solving large models are centered around supercomputer clusters and not consumer hardware, making these large-scale simulations infeasible for smaller research teams or clinical use. To solve these problems, a custom structural linear finite element solver was built and tested to conform to accessible consumer hardware. Maximizing performance, memory efficiency and hardware compatibility were the top priorities for the solver, and thus special care was taken to decrease the memory usage of the mesh by exploiting patterns that occur during meshing, utilizing bi-directional element and node index buffers for faster per node parallelization, all while including both graphics processing unit (GPU) OpenCL and CPU solving support. The developed software solved models up to 1 billion degrees-of-freedom (DOF) on a single consumer GPU with single precision, and models of nearly 600 million DOF were solved when utilizing double precision. When compared to other bone oriented solvers, the new solver outperformed both in solving time and memory usage. The mesh compression allowed the unstructured mesh data to be reduced to just a tiny fraction of the PCG solving vectors, resulting in a memory efficiency ranging from 35 to 37 bytes per DOF. Overall, the solver demonstrated the ability to quickly solve large porous FE models that would typically be unsolvable on regular consumer hardware.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and experimental characterization of a cadaveric stance simulator for residual limb biomechanics.","authors":"David V Herlihy, John M Chomack, David N Paglia, Charlene Wetterstrand, J Patrick O'Connor, Susan E D'Andrea, Jason T Maikos","doi":"10.1088/1873-4030/ae8544","DOIUrl":"10.1088/1873-4030/ae8544","url":null,"abstract":"<p><p>Understanding the biomechanical interaction between residual limbs and prosthetic sockets is essential for optimizing prosthesis design and minimizing tissue injury. Existing cadaveric stance simulators have not been specifically designed to examine socket-residual limb biomechanics. This study designed, constructed, and evaluated a cadaveric stance simulator capable of applying physiologically representative compressive forces through residual limbs. The long-term objective is to utilize dynamic stereo x-ray (DSX) to quantify 3D skin strain at the socket-residual limb interface, for which this simulator serves as a critical foundational step. The simulator combined passive spring compression with active stepper motor control to generate characteristic double-peaked vertical ground reaction force (vGRF) profiles of stance phase. Primary validation was performed under idealized conditions using a rigid prosthesis configuration, with cadaveric testing as a secondary feasibility assessment on two residual limbs with direct force plate measurement. Validation metrics included peak vGRF, peak-to-valley (P2V) ratio, first-to-second peak symmetry (P2P), and loading and unloading rates, with target parameters derived from five participants with transtibial limb loss. Non-parametric analyses compared simulator outputs with control data. Spring-based force estimates were validated against force plate measurements using root mean square (RMS) error and Bland-Altman analyses. Idealized trials showed no significant differences across validation metrics, indicating the simulator closely matched selected physiological loading metrics. Exploratory cadaveric comparisons demonstrated lower peak vGRF, P2V ratio, and unloading rates relative to control participants, attributable to intentional force reductions to preserve tissue integrity. Spring-based force estimates demonstrated preliminary agreement with force plate measurements, supported by RMS error and Bland-Altman analysis. The stance simulator provided a repeatable, adaptable platform for physiologically representative residual limb loading. Its compatibility with DSX imaging establishes a foundation for quantifying 3D skin strain at the socket-residual limb interface, supporting improved socket design and outcomes for individuals with lower limb loss.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148377746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of a morphable human forearm model based on 3D surface scans: enabling semi-automated design of patient-specific splints for military and civilian acute care.","authors":"L A van Ginkel, M Smulders, E Hermans, G J M Tuijthof, T J J Maal, V M A Stirler, G A de Jong","doi":"10.1088/1873-4030/ae7110","DOIUrl":"10.1088/1873-4030/ae7110","url":null,"abstract":"<p><p>Three-dimensional (3D) printed, patient-specific splints may offer an alternative for conventional immobilization methods by enhancing comfort, aeration, and hygiene. However, their broader clinical use remains limited by the complexity of current design workflows. Most existing workflows depend on 3D scans processed with commercial software and on manual or semi-automated computer-aided design procedures that are difficult to reproduce, time-intensive, and often require pot-fit adjustments that are challenging to implement. A scalable modeling framework capable of capturing the substantial anatomical variability of the human forearm is needed to support more automated design pipelines. Morphable models address these limitations by establishing dense point-to-point correspondence across anatomical meshes, enabling a reference shape with fixed topology to deform through a set of parameters to approximate individual anatomies accurately. This study developed and validated a morphable forearm model using 200 structured light scans from 100 healthy adults (41 ± 19 years). Mesh preprocessing, anatomical alignment, and iterative registration were performed using a standardized framework, after which a statistical shape model was constructed and evaluated by comparing deformed mean shapes to original geometries using vertex-to-surface distance metrics. The model achieved a mean reconstruction error of 0.05 ± 0.11 mm, with the largest deviations near mesh boundaries at the hand and upper arm. These results demonstrate that the morphable model accurately represents forearm shape variability and provides a reproducible foundation for semi-automated, patient-specific splint design, thereby supporting the more efficient and clinically scalable implementation of 3D-printed immobilization solutions.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147989776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experimental evaluation of the electrical power output of an uncemented revision hip stem equipped with a piezoelectric element under various everyday activities.","authors":"Franziska Geiger, Henning Bathel, Hendrikje Raben, Ursula van Rienen, Rainer Bader, Daniel Kluess","doi":"10.1088/1873-4030/ae7f8c","DOIUrl":"10.1088/1873-4030/ae7f8c","url":null,"abstract":"<p><p>Smart implants are intended to achieve a longer lifespan in the future through integrated sensory and therapeutic functions. In this way, insufficient osseointegration and loosening of uncemented total hip replacements should be prevented by electrodes attached to the femoral stem, specifically stimulating bone growth to improve fixation and thus avoiding revision. For this function, an energy source is necessary, whereby an internal, autonomous one is desirable. Accordingly, in a previous study, a piezoelectric element was integrated into an uncemented hip stem to convert mechanical energy into electrical energy. However, the electrical output has only been calculated computationally, while in practical applications, energy losses occur during energy storage. Moreover, there is a lack of research on total hip and knee replacements with integrated piezoelectric elements that evaluate electrical power generation during everyday activities other than gait. Therefore, the present study aimed to experimentally determine the generated average electrical power of an uncemented revision hip stem with equipped piezoelectric element during different everyday activities. Furthermore, the storable energy during the most promising activities was evaluated with a standard energy harvesting (SEH) circuit. A simplified test rig was set up for these measurements. The results indicate that jogging and walking, with an average electrical power of 204<i>µ</i>W and 75<i>µ</i>W, respectively, convert the most energy, followed by stairs up and stairs down. After 20 min of jogging, 20.7 mJ were stored in a 330<i>µ</i>F capacitor, while one hour of walking yielded 12.9 mJ in a 470<i>µ</i>F capacitor. The energy required for two 1 cm long stimulation electrodes is estimated to range from 0.1 mJ (10<i>µ</i>A, 1000 Hz) to 254 mJ (100<i>µ</i>A, 20 Hz) for the recommended daily protocol of three 45 min sessions. Accordingly, the harvested energy of 12.9 mJ may be sufficient to support electrical bone stimulation at up to 20<i>µ</i>A over 20-1000 Hz. To increase the stored energy, significant energy losses in the SEH circuit due to impedance mismatch must be minimized by improving the energy harvesting circuitry.</p>","PeriodicalId":49836,"journal":{"name":"Medical Engineering & Physics","volume":"147 7","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}