Recent Patents on Nanotechnology最新文献

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Improved Thermal Performance and Distillate of Conventional Solar Still via Copper Plate, Phase Change Material and CuO Nanoparticles. 通过铜板、相变材料和氧化铜纳米颗粒改善传统太阳能蒸馏器的热性能和蒸馏物。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-03 DOI: 10.2174/0118722105275724231130100817
S Kumaravel, M Nagaraj, G Bharathiraja
{"title":"Improved Thermal Performance and Distillate of Conventional Solar Still via Copper Plate, Phase Change Material and CuO Nanoparticles.","authors":"S Kumaravel, M Nagaraj, G Bharathiraja","doi":"10.2174/0118722105275724231130100817","DOIUrl":"https://doi.org/10.2174/0118722105275724231130100817","url":null,"abstract":"<p><strong>Background: </strong>The world is currently facing a growing concern regarding freshwater scarcity, which has arisen as a result of a complex interplay of various factors. Renewable energy-powered water desalination is a feasible solution to address freshwater scarcity.</p><p><strong>Methods: </strong>This study presents a comprehensive investigation of the performance of a conventional solar still (CSS) and its modified versions, such as a still with copper plates, a still with PCM and a still with PCM and 3 wt% CuO nanoparticles blend. The experiments were carried out concurrently under identical circumstances for the CSS and the proposed stills. Prior to usage, the CuO nanoparticles and their blend with PCM were characterized through various analyses.</p><p><strong>Results: </strong>The investigation showcased the copper plate attached solar still with 3 wt% CuO nanoparticles blended with PCM significantly improved the distillate production, achieving approximately 6.85 kg/m2/day. This represents an increment of approximately 23.42% compared to the still with copper plate and PCM and 69.14% related to the CSS.</p><p><strong>Conclusion: </strong>Moreover, the solar still with 3 wt% CuO nanoparticles blended with PCM demonstrated a thermal efficiency of 74.23% and an exergy efficiency of 9.75%. The production cost of distillate for all four stills remained at $0.03 per kg. These findings highlight the effectiveness of the proposed copper plate attached solar still with 3 wt% CuO nanoparticles blended with PCM as a viable method for producing potable water.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139089100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging and Non-imaging Analytical Techniques Used for Drug Nanosizing and their Patents: An Overview. 用于药物纳米化的成像和非成像分析技术及其专利综述。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/0118722105243388230920013508
Vijay Agarwal, Meenakshi Bajpai
{"title":"Imaging and Non-imaging Analytical Techniques Used for Drug Nanosizing and their Patents: An Overview.","authors":"Vijay Agarwal, Meenakshi Bajpai","doi":"10.2174/0118722105243388230920013508","DOIUrl":"10.2174/0118722105243388230920013508","url":null,"abstract":"<p><strong>Background: </strong>Nanosizing is widely recognized as an effective technique for improving the solubility, dissolution rate, onset of action, and bioavailability of poorly water-soluble drugs. To control the execution and behavior of the output product, more advanced and valuable analytical techniques are required.</p><p><strong>Objective: </strong>The primary intent of this review manuscript was to furnish the understanding of imaging and non-imaging techniques related to nanosizing analysis by focusing on related patents. In addition, the study also aimed to collect and illustrate the information on various classical (laser diffractometry, photon correlation spectroscopy, zeta potential, laser Doppler electrophoresis, X-ray diffractometry, differential scanning calorimeter, scanning electron microscopy, transmission electron microscopy), new, and advanced analytical techniques (improved dynamic light scattering method, Brunauer-Emmett- Teller method, ultrasonic attenuation, biosensor), as well as commercial techniques, like inductively coupled plasma mass spectroscopy, aerodynamic particle sizer, scanning mobility particle sizer, and matrix- assisted laser desorption/ionization mass spectroscopy, which all relate to nano-sized particles.</p><p><strong>Methods: </strong>The present manuscript has taken a fresh look at the various aspects of the analytical techniques utilized in the process of nanosizing, and has achieved this through the analysis of a wide range of peer-reviewed literature. All summarized literature studies provide the information that can meet the basic needs of nanotechnology.</p><p><strong>Results: </strong>A variety of analytical techniques related to the nanosizing process have already been established and have great potential to weed out several issues. However, the current scenarios require more relevant, accurate, and advanced analytical techniques that can minimize the time and deviations associated with different instrumental and process parameters. To meet this requirement, some new and more advanced analytical techniques have recently been discovered, like ultrasonic attenuation technique, BET technique, biosensors, etc. Conclusion: The present overview certifies the significance of different analytical techniques utilized in the nanosizing process. The overview also provides information on various patents related to sophisticated analytical tools that can meet the needs of such an advanced field. The data show that the nanotechnology field will flourish in the coming future.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"494-518"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanocrystal Materials for Resistive Memory and Artificial Synapses: Progress and Prospects. 用于电阻记忆和人工突触的纳米晶体材料:进展与前景》。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230413092108
Yingchun Chen, Dunkui Chen, Chi Zhang, Xian Zhang
{"title":"Nanocrystal Materials for Resistive Memory and Artificial Synapses: Progress and Prospects.","authors":"Yingchun Chen, Dunkui Chen, Chi Zhang, Xian Zhang","doi":"10.2174/1872210517666230413092108","DOIUrl":"10.2174/1872210517666230413092108","url":null,"abstract":"<p><strong>Background: </strong>Resistive random-access memory (RRAM) is considered to be the most promising next-generation non-volatile memory because of its low cost, low energy consumption, and excellent data storage characteristics. However, the on/off (SET/RESET) voltages of RRAM are too random to replace the traditional memory. Nanocrystals (NCs) offer an appealing option for these applications since they combine excellent electronic/optical properties and structural stability and can address the requirements of low-cost, large-area, and solution-processed technologies. Therefore, the doping NCs in the function layer of RRAM are proposed to localize the electric field and guide conductance filaments (CFs) growth.</p><p><strong>Objective: </strong>The purpose of this article is to focus on a comprehensive and systematical survey of the NC materials, which are used to improve the performance of resistive memory (RM) and optoelectronic synaptic devices and review recent experimental advances in NC-based neuromorphic devices from artificial synapses to light-sensory synaptic platforms.</p><p><strong>Methods: </strong>Extensive information related to NCs for RRAM and artificial synapses and their associated patents were collected. This review aimed to highlight the unique electrical and optical features of metal and semiconductor NCs for designing future RRAM and artificial synapses.</p><p><strong>Results: </strong>It was demonstrated that doping NCs in the function layer of RRAM could not only improve the homogeneity of SET/RESET voltage but also reduce the threshold voltage. At the same time, it could still increase the retention time and provide the probability of mimicking the bio-synapse.</p><p><strong>Conclusion: </strong>NC doping can significantly enhance the overall performance of RM devices, but there are still many problems to be solved. This review highlights the relevance of NCs for RM and artificial synapses and also provides a perspective on the opportunities, challenges, and potential future directions.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"237-255"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9687973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel and Innovative Approach of Nanotechnology with their Applications in the Management of Infectious Disease, Tuberculosis: An Overview. 纳米技术的创新方法及其在传染病、结核病管理中的应用综述。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210516666220523122724
Sonia Singh, Ashima Ahuja
{"title":"Novel and Innovative Approach of Nanotechnology with their Applications in the Management of Infectious Disease, Tuberculosis: An Overview.","authors":"Sonia Singh, Ashima Ahuja","doi":"10.2174/1872210516666220523122724","DOIUrl":"10.2174/1872210516666220523122724","url":null,"abstract":"<p><p>Tuberculosis (TB) is considered a significant health problem caused by <i>Mycobacterium tuberculosis</i>. It is one of the second-deadly infectious diseases right after AIDS. Several factors such as poor patient compliance, high dose intake, low drug bioavailability and prolonged treatment of disease are responsible for the prevalence of multi-drug resistance tuberculosis and extensively drug-resistant tuberculosis cases. Therefore, developing such drug-resistant bacterial strains has created a robust and efficient system that can improve the therapeutic effectiveness of anti-tubercular drugs. This review manuscript highlights the therapeutic outcomes of a nanotechnology-based drug delivery system in treating TB. Various novel nanoformulations for anti-mycobacterial drugs have been explored. Such novel approaches would have shown several advantages such as sustained/controlled drug release, reduced dose frequency, and resolved poor patient compliance over many free anti-tubercular drugs. This framework will provide valuable information on various nanoparticle-based technology employed in treating TB infectious disease. Patent data were searched in google patent and nanoformulations outcomes for TB management improves health of patients.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"1 1","pages":"140-163"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41333862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Critical Appraisal of Functionalized 2-Dimensional Carbon-Based Nanomaterials for Drug Delivery Applications. 功能化二维碳基纳米材料在药物递送应用中的关键评价。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210518666230911150337
Dilpreet Singh, G D Gupta, Nimish Gupta, Princi Verma, Abhisek Dey, Simranjeet Kaur, Akshay Kumar, Namandeep Raj
{"title":"A Critical Appraisal of Functionalized 2-Dimensional Carbon-Based Nanomaterials for Drug Delivery Applications.","authors":"Dilpreet Singh, G D Gupta, Nimish Gupta, Princi Verma, Abhisek Dey, Simranjeet Kaur, Akshay Kumar, Namandeep Raj","doi":"10.2174/1872210518666230911150337","DOIUrl":"10.2174/1872210518666230911150337","url":null,"abstract":"<p><p>The development of an efficient and innovative drug delivery system is essential to improve the pharmacological parameters of the medicinal compound or drug. The technique or manner used to improve the pharmacological parameters plays a crucial role in the delivery system. In the current scenario, various drug delivery systems are available where nanotechnology has firmly established itself in the field of drug delivery. One of the most prevalent elements is carbon with its allotropic modifications such as graphene-based nanomaterials, carbon nanotubes, carbon dots, and carbon fullerenes, these nanomaterials offer notable physiochemical and biochemical properties for the delivery applications due to their smaller size, surface area, and ability to interact with the cells or tissues. The exceptional physicochemical properties of carbon-based 2D nanomaterials, such as graphene and carbon nanotubes, make them attractive candidates for drug delivery systems. These nanomaterials offer a large surface area, high drug loading capacity, and tunable surface chemistry, enabling efficient encapsulation, controlled release, and targeted delivery of therapeutic agents. These properties of the nanomaterials can be exploited for drug delivery applications, like assisting the target delivery of drugs and aiding combination molecular imaging. This review emphasizes on the recent patents on 2D carbon-based nanomaterial and their role in drug delivery systems. Carbon-based 2D nanomaterials present a wealth of opportunities for advanced drug delivery systems. Their exceptional properties and versatility offers great potential in improving therapeutic efficacy, minimizing side effects, and enabling personalized medicine and the recent patents on 2D nanomaterial.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"479-493"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10590718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-dimensional MXene Nanomaterials: Preparation, Structure Modulation and the Applications in Electrochemical Energy Storage. 二维 MXene 纳米材料:二维 MXene 纳米材料:制备、结构调制及在电化学储能中的应用。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230427161120
Yingchun Chen, Bei Yu, Lingling Peng
{"title":"Two-dimensional MXene Nanomaterials: Preparation, Structure Modulation and the Applications in Electrochemical Energy Storage.","authors":"Yingchun Chen, Bei Yu, Lingling Peng","doi":"10.2174/1872210517666230427161120","DOIUrl":"10.2174/1872210517666230427161120","url":null,"abstract":"<p><strong>Background: </strong>MXenes have attracted intensive attention owing to their unique twodimensional (2D) layered structure, high specific surface area, excellent conductivity, superior surface hydrophilicity, and chemical stability. In recent years, selective etching of the A element layers from MAX phases by fluorine-containing etchants (HF, LiF-HCl, <i>etc</i>) is a common method to prepare multilayered MXene nanomaterials (NMs) with plentiful surface terminations. At present, many studies have been reported on the use of fluorine-free etchants (NaOH, ZnCl<sub>2</sub>, <i>etc</i>) to etch MAX phases. The properties of MXene NMs are dependent on their structures.</p><p><strong>Objective: </strong>The purpose of this review is to focus on a comprehensive and systematical survey on the preparation, structure modulation, and applications of MXene NMs in electrochemical energy storage devices, including supercapacitors, lithium-ion battery, sodium-ion battery, potassium-ion battery, and aluminum-ion battery.</p><p><strong>Methods: </strong>Extensive information related to the preparation and applications of 2D MXene NMs for electrochemical energy storage and their associated patents were collected. This review highlights the recently reported 2D MXene NMs which are used in supercapacitor and various metal ion.</p><p><strong>Results: </strong>It is found that the preparation methods have great impacts on the layer spacing and surface terminations of MXenes, consequently affecting their performance. Hence, this paper summarizes the research progress of the preparation strategies, layer spacing and surface termination modulation of MXene NMs.</p><p><strong>Conclusion: </strong>The applications of 2D MXene NMs in electrochemical energy storage are outlined. The forward-looking challenges and prospects for the development of MXenes are also proposed.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"92-116"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9711720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Apoptotic-targeted Phytoconstitutent-loaded Antipsoriatic Nanobiocomposites. 以细胞凋亡为目标的植物成分负载型抗银屑病纳米生物复合材料的作用
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230201103935
Pankaj Singh Patel, Rajnish Srivastava, Sunita Panchawat
{"title":"Role of Apoptotic-targeted Phytoconstitutent-loaded Antipsoriatic Nanobiocomposites.","authors":"Pankaj Singh Patel, Rajnish Srivastava, Sunita Panchawat","doi":"10.2174/1872210517666230201103935","DOIUrl":"10.2174/1872210517666230201103935","url":null,"abstract":"<p><p>Psoriasis is an inflammatory and proliferative autoimmune dermatological disorder. It is a skin ailment that is defined by particular, drab-red or peach-pink stiff areas with silvery scales patches. Other typical characteristics include the proliferation of epidermal layer, aberrant keratinization, hyperkeratosis, increased micro capillary vascularization, and infiltration of inflammatory mediator loaded cells. Conventional pharmacotherapies currently available can only provide minor advantages. Nanomedicines based on nanotechnology can potentially improve the efficacy and safety of psoriasis medications. Apoptosis plays an important pathogenetic role in many chronic inflammatory diseases, including those of dermatological interest, in particular, regarding psoriasis. In this regard, treatments with antioxidant properties could be appropriate therapeutic options. We reviewed the available studies on the efficacy of antiapoptotic therapies in psoriasis. We'll look at phytochemicals in this review, which are natural components found in plants with antiapoptotic activity that are frequently used to treat psoriasis. For improved topical treatment, we also take into consideration the advantages of loading phytoconstituents as medicines into lipid based nanocarriers. The utilization of herbal nanomedicines in psoriasis, as well as nano delivery carrier system for phytoconstituents with improved therapeutic profiles and decreased toxicity, are the subjects of this review. The study's purpose is to find more effective herbal nanomedicines for treating psoriasis. In the treatment of psoriasis, phytoconstituents that have shown antipsoriatic potential in recent years, as well as phytoconstituents loaded based nanomedicines, have a lot of promising roles to be explored. Furthermore, very few patents have been found in the field of nanotechnology utilizing lipid-based nanocarrier system for the treatment of psoriasis. Therefore, this review greatly compels the researcher to validate the process development of lipid-based drug delivery system for the patentability of the product. This should be in a view of shifting in the applicability of the drug delivery system for general public health as a potential treatment option in psoriasis.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"220-236"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10656806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comprehensive Review on Prospects of Polymeric Nanoparticles for Treatment of Diabetes Mellitus: Receptors-Ligands, In vitro & In vivo Studies. 聚合物纳米粒子治疗糖尿病前景综述:受体-配体、体外和体内研究。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230803091245
Arinjay Jain, Shilpa Dawre
{"title":"A Comprehensive Review on Prospects of Polymeric Nanoparticles for Treatment of Diabetes Mellitus: Receptors-Ligands, <i>In vitro</i> & <i>In vivo</i> Studies.","authors":"Arinjay Jain, Shilpa Dawre","doi":"10.2174/1872210517666230803091245","DOIUrl":"10.2174/1872210517666230803091245","url":null,"abstract":"<p><p>As per International Diabetes Federation Report 2022, worldwide diabetes mellitus (DM) caused 6.7M moralities and ~537M adults suffering from diabetes mellitus. It is a chronic condition due to β-cell destruction or insulin resistance that leads to insulin deficiency. This review discusses Type-1 DM and Type-2 DM pathophysiology in detail, with challenges in management and treatment. The toxicity issues of conventional drugs and insulin injections are complex to manage. Thus, there is a need for technological intervention. In recent years, nanotechnology has found a fruitful advancement of novel drug delivery systems that might potentially increase the efficacy of anti-diabetic drugs. Amongst nano-formulations, polymeric nanoparticles have been studied to enhance the bioavailability and efficacy of anti-diabetic drugs and insulin. In the present review, we summarized polymeric nanoparticles with different polymers utilized to deliver anti-diabetic drugs with <i>in vitro</i> and <i>in vivo</i> studies. Furthermore, this review also includes the role of receptors and ligands in diabetes mellitus and the utilization of receptor-ligand interaction to develop targeted nanoparticles. Additionally, we discussed the utility of nanoparticles for the delivery of phytoconstituents which aids in protecting the oxidative stress generated during diabetes mellitus. Atlast, this article also comprises of numerous patents that have been filed or granted for the delivery of antidiabetic and anticancer molecules for the treatment of diabetes mellitus and pancreatic cancer.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"457-478"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10284198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Overview of Metallic Nanoparticles: Classification, Synthesis, Applications, and their Patents. 金属纳米粒子概述:分类、合成、应用及其专利。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230901114421
Sarika Dhir, Shailendra Bhatt, Mahima Chauhan, Vandana Garg, Rohit Dutt, Ravinder Verma
{"title":"An Overview of Metallic Nanoparticles: Classification, Synthesis, Applications, and their Patents.","authors":"Sarika Dhir, Shailendra Bhatt, Mahima Chauhan, Vandana Garg, Rohit Dutt, Ravinder Verma","doi":"10.2174/1872210517666230901114421","DOIUrl":"10.2174/1872210517666230901114421","url":null,"abstract":"<p><strong>Background: </strong>Nanotechnology has gained enormous attention in pharmaceutical research. Nanotechnology is used in the development of nanoparticles with sizes ranging from 1-100 nm, with several extraordinary features. Metallic nanoparticles (MNPs) are used in various areas, such as molecular biology, biosensors, bio imaging, biomedical devices, diagnosis, pharmaceuticals, etc., for their specific applications.</p><p><strong>Methodology: </strong>For this study, we have performed a systematic search and screening of the literature and identified the articles and patents focusing on various physical, chemical, and biological methods for the synthesis of metal nanoparticles and their pharmaceutical applications.</p><p><strong>Results: </strong>A total of 174 references have been included in this present review, of which 23 references for recent patents were included. Then, 29 papers were shortlisted to describe the advantages, disadvantages, and physical and chemical methods for their synthesis, and 28 articles were selected to provide the data for biological methods for the formulation of metal NPs from bacteria, algae, fungi, and plants with their extensive synthetic procedures. Moreover, 27 articles outlined various clinical applications of metal NPs due to their antimicrobial and anticancer activities and their use in drug delivery.</p><p><strong>Conclusion: </strong>Several reviews are available on the synthesis of metal nanoparticles and their pharmaceutical applications. However, this review provides updated research data along with the various methods employed for their development. It also summarizes their various advantages and clinical applications (anticancer, antimicrobial drug delivery, and many others) for various phytoconstituents. The overview of earlier patents by several scientists in the arena of metallic nanoparticle preparation and formulation is also presented. This review will be helpful in increasing the current knowledge and will also inspire to innovation of nanoparticles for the precise and targeted delivery of phytoconstituents for the treatment of several diseases.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"415-432"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10553354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mapping the Nanotechnology Patent Landscape in the Field of Cancer. 绘制癌症领域的纳米技术专利图。
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230530162115
Haoyu Sun, Tong Wu, Xinrui Liu, Huanzhang Xia, Hongmei Yuan
{"title":"Mapping the Nanotechnology Patent Landscape in the Field of Cancer.","authors":"Haoyu Sun, Tong Wu, Xinrui Liu, Huanzhang Xia, Hongmei Yuan","doi":"10.2174/1872210517666230530162115","DOIUrl":"10.2174/1872210517666230530162115","url":null,"abstract":"<p><strong>Background: </strong>Currently, cancer is still a significant disease that seriously endangers human health. Therefore, advanced diagnostic technology and treatment protocols are urgently needed. The rapid development of nanotechnology is expected to provide new ideas for cancer diagnosis and treatment.</p><p><strong>Objective: </strong>The research aims to comprehensively demonstrate the hotspots of nanotechnology applications in cancer.</p><p><strong>Methods: </strong>In this study, an International Patent Classification codes co-occurrence network is constructed to visualize the technology landscape by simultaneously locating and ranking technologies that play an integral role in nanotechnology diffusion and bridging in the field of cancer. In addition, community identification and topic modeling highlight the latent topics in patent documents.</p><p><strong>Results: </strong>The visualization results of the patent network yield five main clusters: Cluster 0 is a nanoparticle composition delivery system with liposomes as the primary carrier. Cluster 1 is mainly represented by nano-immunotherapy with immune checkpoint inhibitors. Cluster 2 is nano phototherapy based on photodynamic therapy and photothermal therapy. Cluster 3 is diagnostic imaging involving nanotechnology. Cluster 4 is a drug delivery system with nanovesicles and albumin nanoparticles as carriers.</p><p><strong>Conclusion: </strong>It was found that carriers represented by liposomes, vesicles, and albumin nanoparticles are essential nanomaterials in the current anticancer drug delivery systems. Integrating next-generation immunosuppressants and nanotechnology will become an important development direction for future immunotherapy. Organic/inorganic nanomaterials are pivotal in cancer imaging diagnosis and phototherapy.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"321-334"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9551890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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