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Recent Patents on Nanotechnology最新文献

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A Complete Sojourn of Current Trends in Gastro-retentive Drug Delivery System: Recent Advances and Patent Survey. 胃肠道留置给药系统当前趋势概览：最新进展与专利调查
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2024-01-01 DOI: 10.2174/1872210517666230331083346
Abhisek Dey, Amrinder Singh, Balak Das Kurmi, Dilpreet Singh
{"title":"A Complete Sojourn of Current Trends in Gastro-retentive Drug Delivery System: Recent Advances and Patent Survey.","authors":"Abhisek Dey, Amrinder Singh, Balak Das Kurmi, Dilpreet Singh","doi":"10.2174/1872210517666230331083346","DOIUrl":"10.2174/1872210517666230331083346","url":null,"abstract":"<p><p>The current work aims to provide a complete sojourn on gastro-retentive drug delivery system (GRDDS) along with formulation methods, polymer selection, and in vitro/ in vivo challenges with finished dosage forms. Ideally, a biopharmaceutical-hindered drug has a rapid clearance and erratic bioavailability due to its low aqueous solubility and permeability. Additionally, it also suffers from high first-pass metabolism and pre-systemic gut wall clearance. Gastro-retentive drug delivery systems have become an emerging technology where newer methodologies and scientific approaches have been used to provide the controlled release of drugs and provide a protective mechanism in the stomach. By the virtue of utilizing GRDDS as a dosage form, these formulations increase Gastroretention time (GRT) which prolongs the controlled release of the drug in the dosage form. GRDDS contribute to increased drug bioavailability and targeting at a site of action, which enhances therapeutic action and offers significant patient compliance. Furthermore, the present work also highlighted the critical role of polymers in favoring drug retention across GIT with the mechanism of gastro-retention and recommended concentration ranges. The emerging technology is also highlighted by the approved drug products and patented formulations in the recent decade which is depicted in a justified manner. GRDDS formulations have demonstrated clinical efficacy, which is supported by a compilation of patents for cutting-edge innovations in dosage forms that can be held in the stomach for an extended period of time.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":"190-206"},"PeriodicalIF":2.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9233841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design, Reliability Modeling and Evaluation of FTSM FTSM的设计、可靠性建模与评估
4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2023-12-13 DOI: 10.2174/9789815165340123010006
Shilpa Gupta
{"title":"Design, Reliability Modeling and Evaluation of FTSM","authors":"Shilpa Gupta","doi":"10.2174/9789815165340123010006","DOIUrl":"https://doi.org/10.2174/9789815165340123010006","url":null,"abstract":"It has been proved that the use of multiplexers and demultiplexers of the smallest size has improved reliability to an extent but the effect of using bigger-sized MUX and DEMUX on reliability and fault tolerance must also be evaluated. In the recent past, the consequences of using higher-sized MUXs and DEMUXs have been explored and presented in this chapter. The full analysis of the size of MUXs and DEMUXs to be used so as to increase the reliability of the network to the optimum level has been presented. The analysis done on SEN MIN shows that the best size of MUXs and DEMUXs to be used is 4×1 and 1×4 respectively and hence the SEN MIN with 4×1 MUX and 1×4 DEMUX is named Fault Tolerance SEN MIN (FTSM).","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"1 1","pages":"134-158"},"PeriodicalIF":0.0,"publicationDate":"2023-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147917365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging Treatment Options of Pluronic in Designing Colloidal Nano and Microcarriers Carriers for Various Therapies Pluronic在设计用于各种治疗的胶体纳米和微载体方面的新治疗选择
4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2023-11-07 DOI: 10.2174/0118722105255391231018112747
Ravinder Verma, Laxmi Rani, Sweta Kamboj, Rohit Kamboj, Tanu Kamboj, Shailendra Bhatt
{"title":"Emerging Treatment Options of Pluronic in Designing Colloidal Nano and Microcarriers Carriers for Various Therapies","authors":"Ravinder Verma, Laxmi Rani, Sweta Kamboj, Rohit Kamboj, Tanu Kamboj, Shailendra Bhatt","doi":"10.2174/0118722105255391231018112747","DOIUrl":"https://doi.org/10.2174/0118722105255391231018112747","url":null,"abstract":"Poloxamers, commonly known as Pluronics, are a special family of synthetic tri-block copolymers with a core structure made of hydrophobic poly (propylene oxide) chains sandwiched by two hydrophilic poly (ethylene oxide) chains. It is possible to modify the mechanical, bioactive, and microstructural characteristics of Pluronics to simulate the behavior of different types of tissues. Additionally, they are auspicious drug carriers with the capacity to increase therapeutic agent availability and to design nano-drug formulations for various ailments. The nanoformulation composed of Pluronics is more susceptible to cancer cells due to their amphiphilic nature and feature of selfassembling into micelles. Today's expanding poloxamer research is creating new hopes that increase the possibility of new remedies for a brand-new nanomedicine age treatment. This article provides a concise overview of the classification, grading, and attributes of drug delivery systems (DDSs) as well as the potential for Pluronics to create micro and nanocarriers. We subsequently discuss its utility in drug delivery for cancer, gene therapy, anti-infective therapy, antioxidants, anti-diabetic drugs, anti-HIV, Alzheimer's disease, and antimicrobial drugs. This review also highlighted several patented formulations that contain various grades of Pluronics in one or more different ways. The recent findings in fundamental research in the field properly demonstrate the strong interest in these novel pharmaceutical strategies.","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"116 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135541456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
INVASOMES: New Carriers for Transdermal Delivery of Anticancer Drugs invasome:抗肿瘤药物经皮递送的新载体
4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2023-10-11 DOI: 10.2174/0118722105254232230920053519
Lalit Kumar
{"title":"INVASOMES: New Carriers for Transdermal Delivery of Anticancer Drugs","authors":"Lalit Kumar","doi":"10.2174/0118722105254232230920053519","DOIUrl":"https://doi.org/10.2174/0118722105254232230920053519","url":null,"abstract":"<jats:sec>\u0000<jats:title />\u0000<jats:p />\u0000</jats:sec>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136254093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comprehensive Review on Recent Advances and Patents of Niosomes niosome的研究进展及专利综述
4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2023-10-10 DOI: 10.2174/0118722105259776231002071218
Sushma Verma, Sakshi Saharawat
{"title":"A Comprehensive Review on Recent Advances and Patents of Niosomes","authors":"Sushma Verma, Sakshi Saharawat","doi":"10.2174/0118722105259776231002071218","DOIUrl":"https://doi.org/10.2174/0118722105259776231002071218","url":null,"abstract":"Abstract: Niosomes are novel, self-assembled vesicular carriers that deliver both lipophilic and hydrophilic drugs at the specific site in a targeted way, enhancing bioavailability and extending therapeutic effects. Niosomes are a versatile drug delivery system with a diverse range of applications from gene to brain-targeted delivery and they are more attractive choices than liposomes as they are efficient at biodegrading. Niosome offers several advantages over conventional drug delivery systems, including enhanced stability, and also have gained a lot of focus in natural product delivery in recent years. This review provides a comprehensive view of niosomal research and recent advancements, including classification and fabrication methods, and their role in drug delivery and targeting. The description of the rise in niosomal formulation patents around the world is also elaborated along with the natural product delivery of niosomes which has recently gained significance. Patents on novel preparation, loading, and modification techniques have enhanced the importance of niosome in the pharmaceutical industry.","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136361067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patent Selections 专利的选择
4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2023-09-01 DOI: 10.2174/187221051703230215165620
{"title":"Patent Selections","authors":"","doi":"10.2174/187221051703230215165620","DOIUrl":"https://doi.org/10.2174/187221051703230215165620","url":null,"abstract":"","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135736237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
WITHDRAWN: Expression and Clinical Significance of Cat B and sICAM-1 in the GCF of Patients with Peri-implantitis WITHDRAWN：Cat B和sICAM-1在种植体周围炎患者GCF中的表达及其临床意义
IF 2 4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2023-08-18 DOI: 10.2174/1872210517666230818161525
Jichao Lin, Yanjun Lin, Youcheng Yu, Qinglian Wang
{"title":"WITHDRAWN: Expression and Clinical Significance of Cat B and sICAM-1 in the GCF of Patients with Peri-implantitis","authors":"Jichao Lin,&nbsp;Yanjun Lin,&nbsp;Youcheng Yu,&nbsp;Qinglian Wang","doi":"10.2174/1872210517666230818161525","DOIUrl":"10.2174/1872210517666230818161525","url":null,"abstract":"<p><p>The article has been withdrawn at the request of the authors of the journal Recent Patents on Nanotechnology.</p><p><p>Bentham Science apologizes to the readers of the journal for any inconvenience this may caused.</p><p><p>The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policiesmain.php</p><p><strong>Bentham science disclaimer: </strong>It is a condition of publication that manuscripts submitted to this journal have not been published and will not be\u0000simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been\u0000published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is\u0000strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal\u0000right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By\u0000submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and\u0000when the article is accepted for publication.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2023-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10078160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design of Antimalarial Compounds on Quinoline Scaffold: From Plant to Drug 喹啉支架上抗疟化合物的设计：从植物到药物
4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2023-06-05 DOI: 10.2174/9789815123678123030010
Paulo F. S. Santos-Júnior, Igor José dos Santos Nascimento, Geraldo J. S. Neto, Rafael Jorge Melo de Omena, Thiago Mendonça de Aquino, João Xavier de Araújo‐Júnior, Mário R. Meneghetti, Edeildo Ferreira da Silva‐Júnior
{"title":"Design of Antimalarial Compounds on Quinoline Scaffold: From Plant to Drug","authors":"Paulo F. S. Santos-Júnior, Igor José dos Santos Nascimento, Geraldo J. S. Neto, Rafael Jorge Melo de Omena, Thiago Mendonça de Aquino, João Xavier de Araújo‐Júnior, Mário R. Meneghetti, Edeildo Ferreira da Silva‐Júnior","doi":"10.2174/9789815123678123030010","DOIUrl":"https://doi.org/10.2174/9789815123678123030010","url":null,"abstract":"Plasmodium species are responsible for a high incidence of cases and resistance, even with several approved drugs. Quinoline derivatives are recognized as a source of active compounds, where tafenoquine has been recently approved. Cases of resistance and the indiscriminate use of anti-malarials against COVID-19 have negatively contributed to eradicating this disease. In this context, modifications at 2- or 4-amino positions from the quinoline scaffold or even its metal complexes have shown promising advances in the field, especially against resistant strains, such as 3D7, W2, D10, Dd2, K1 , and FCR-3. In this chapter, we discussed all aspects involving such compounds, presenting their results based on SAR analysis and recent contributions/advances involving this classic scaffold arising from nature.&lt;br&gt;","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"1 1","pages":"189-237"},"PeriodicalIF":0.0,"publicationDate":"2023-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147912607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Meet the Editorial Board Member 与编辑委员会成员见面
4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2023-06-01 DOI: 10.2174/187221051702221121141420
Tapas K. Bandyopadhyay
{"title":"Meet the Editorial Board Member","authors":"Tapas K. Bandyopadhyay","doi":"10.2174/187221051702221121141420","DOIUrl":"https://doi.org/10.2174/187221051702221121141420","url":null,"abstract":"","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135275270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patent Selections 专利的选择
4区 材料科学
Recent Patents on Nanotechnology Pub Date : 2023-06-01 DOI: 10.2174/187221051702221121151611
{"title":"Patent Selections","authors":"","doi":"10.2174/187221051702221121151611","DOIUrl":"https://doi.org/10.2174/187221051702221121151611","url":null,"abstract":"","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135275271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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