{"title":"A Comprehensive Review of Therapeutic Approaches Available for the Treatment of Dermatitis.","authors":"Apoorva Singh, Nimisha","doi":"10.2174/1872210515666210806143015","DOIUrl":"https://doi.org/10.2174/1872210515666210806143015","url":null,"abstract":"<p><strong>Background: </strong>Dermatitis or eczema is a prevalent skin disorder worldwide and is also very common as a pediatric inflammatory skin disorder. Its succession gets worse with the multiple comorbidities which exhibit mechanisms that are poorly understood. Its management further becomes a challenge due to the limited effective treatment options available. However, the Novel Drug Delivery Systems (NDDS) along with new targeting strategies can easily bypass the issues associated with dermatitis management. If we compare the active constituents against phytoconstituents effective against dermatitis then phytoconstituents can be perceived to be more safe and gentle.</p><p><strong>Objective: </strong>Administration of NDDS of plant extract or actives displays improved absorption behavior, which helps them to permeate through lipid-rich biological membrane leading to increased bioavailability. The newer efficient discoveries related to eczema can face various exploitations. This can be intervened by the subjection of patent rights, which not only safeguard the novel works of individual(s) but also give them the opportunity to share details of their inventions with people globally.</p><p><strong>Conclusion: </strong>The present review focuses on the available research about the use of nanoformulations in the topical delivery. It further elaborates the use of different animal models as the basis to characterize the different features of dermatitis. The review also highlights the recent nanoformulations which have the ability to amplify the delivery of active agents through their incorporation in transfersomes, ethosomes, niosomes or phytosomes, etc.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"16 3","pages":"172-197"},"PeriodicalIF":2.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39289594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hafiz Muhammad Asif Javed, Muhammad Sarfaraz, Asif Mahmood, M Zubair Nisar, Akbar Ali Qureshi, Muhammad Azhar Khan, Peng Zhong, Yulong Liao
{"title":"Design and Development of a Solar Water Purification System with Graphene-Plasmonic Based Hybrid Nanocomposites: A Review.","authors":"Hafiz Muhammad Asif Javed, Muhammad Sarfaraz, Asif Mahmood, M Zubair Nisar, Akbar Ali Qureshi, Muhammad Azhar Khan, Peng Zhong, Yulong Liao","doi":"10.2174/1872210515666210609151201","DOIUrl":"https://doi.org/10.2174/1872210515666210609151201","url":null,"abstract":"<p><p>Harvesting solar energy for water treatments has been considered a promising solution for a global community. The shortage of water is a great challenge for scientists due to the increased demand of the population-however, the low efficiency of absorber materials obstacles in practical applications. In addition, state-of-the-art conventional technologies require optical concentrators and multiple component-based systems, leading to lower efficiency and higher cost. In this review, a low-cost, more reliable, less energy-intensive, and more eco-friendly solar water purification system based on graphene-plasmonic hybrid nanocomposite has been demonstrated. Graphene-plasmonic-based hybrid nanocomposite has been utilized to achieve pure water from wastewater. Such hybrid nanocomposites have the ability to clean polluted water very efficiently due to their excellent properties such as higher surface area, low concentration, and working ability. Furthermore, the development of a solar water purification system has been achieved through optimized hybrid nanocomposites.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"16 1","pages":"30-44"},"PeriodicalIF":2.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39727257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Withdrawal Notice: Development of Itraconazole Loaded Transethosomes for Improved Transdermal Delivery","authors":"Koushlesh Kumar Mishra","doi":"10.2174/1872210515666211129115811","DOIUrl":"10.2174/1872210515666211129115811","url":null,"abstract":"<p><p>The article has been withdrawn at the request of the editor of the journal Recent Patents on Nanotechnology due to incoherent content.</p><p><p>Bentham Science apologizes to the readers of the journal for any inconvenience this may caused.</p><p><p>The Bentham Editorial Policy on Article Withdrawal can be found at https://benthamscience.com/editorial-policiesmain.php</p><p><strong>Bentham science disclaimer: </strong>It is a condition of publication that manuscripts submitted to this journal have not been published and will not be\u0000simultaneously submitted or published elsewhere. Furthermore, any data, illustration, structure or table that has been published elsewhere must be reported, and copyright permission for reproduction must be obtained. Plagiarism is\u0000strictly forbidden, and by submitting the article for publication the authors agree that the publishers have the legal\u0000right to take appropriate action against the authors, if plagiarism or fabricated information is discovered. By\u0000submitting a manuscript, the authors agree that the copyright of their article is transferred to the publishers if and\u0000when the article is accepted for publication.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2021-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39677591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Meet The Editorial Board Member","authors":"C. Balázsi","doi":"10.2174/187221051503210916164354","DOIUrl":"https://doi.org/10.2174/187221051503210916164354","url":null,"abstract":"Dr. Csaba Balázsi (MSc-1993, PhD-2000, DSc-2014) is a Scientific Adviser in Centre for Energy Research of Hungarian Academy of Sciences. He is a metallurgical engineer with 20+ years of practice in various physical and chemical technologies of nanocomposite manufacturing, including nanomilling, hydrothermal, powder metallurgy, sintering, electrospinning. His research area covers R&D of high performance materials for medical, sensor and high temperature applications. He was involved in the development of nanoporous hexagonal tungsten oxide materials for gas sensors, carbon nanotube/graphene nano-platelet added silicon nitride ceramic composites for tribological applications and several other nanocomposites, including polymer based biocompatible composites for orthopedics. He is principal investigator or co-PI in several national (OTKA, NKTH, TéT, Eötvös, Bolyai) and international (FP7, NATO, NSF, ESA) research grants.","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"1 1","pages":""},"PeriodicalIF":2.0,"publicationDate":"2021-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41448622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
John O Origomisan, Woei J Lau, Farhana Aziz, Ahmad F Ismail
{"title":"Impacts of Secondary Mixed Monomer on Properties of Thin Film Composite (TFC) Nanofiltration and Reverse Osmosis Membranes: A Review.","authors":"John O Origomisan, Woei J Lau, Farhana Aziz, Ahmad F Ismail","doi":"10.2174/1872210514666201014152621","DOIUrl":"https://doi.org/10.2174/1872210514666201014152621","url":null,"abstract":"<p><p>Polyamide (PA) Thin-Film Composite (TFC) membranes are widely used for large-scale water and wastewater treatment processes worldwide owing to their good balance between water permeability and dissolved solutes separation rate. The physicochemical properties of the cross-linked PA layer are the main criteria determining the filtration performance of the resultant TFC membrane, and this selective layer can be created through Interfacial Polymerization (IP) between two immiscible active monomers, i.e., amine monomer in aqueous solution and acyl chloride monomer in organic solution. This patent review article intends to provide insights to researchers in fabricating improved properties of TFC membranes through the utilization of secondary monomers during IP process. To the best of our knowledge, this is the first review that gives a state-of-the-art account of the subject matter by emphasizing the impacts of secondary monomers (both amine and acyl chloride monomers) on the properties of conventional TFC membranes for nanofiltration and reverse osmosis applications. Our review indicated that the introduction of secondary monomers into either aqueous or organic solution could alter the physical and chemical properties of PA layer, which led to variations in membrane filtration performance. Nevertheless, more research is still required, as most of the secondary monomers reported in the literature did not overcome the membrane trade-off effect between permeability and selectivity. The subject of improved PA layer development is a multi-disciplinary study that requires researchers with different backgrounds (e.g., materials science, chemistry, physics and engineering) to work together.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"15 2","pages":"105-124"},"PeriodicalIF":2.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38490574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Recent Overview on Dermatological Applications of Liposomes.","authors":"Poonam Kushwaha, Sumedha Saxena, Babita Shukla","doi":"10.2174/1872210514666201021145233","DOIUrl":"https://doi.org/10.2174/1872210514666201021145233","url":null,"abstract":"<p><strong>Background: </strong>In dermatology, the topical application of liposomes has proven to be of therapeutic value. Many drugs encapsulated into liposomes have shown enhanced skin penetration.</p><p><strong>Methods: </strong>Liposomes are lipid based spherical vesicles. In structure and composition, they resemble cell membrane. Because of their amphipathic nature, they can be used as carriers for hydrophilic as well as lipophilic therapeutic agents. These liposomal systems can easily get integrated with the skin lipids and maintain the desired hydration conditions to improve drug penetration and localization in the skin layers.</p><p><strong>Results: </strong>Considering the need for topical delivery and the promising potential of liposomes, an attempt has been made to explore the recent advances of liposome-based formulations in dermatological applications.</p><p><strong>Conclusion: </strong>This patent summarizes the recent findings of liposome-based formulations for dermal delivery of drugs.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"15 4","pages":"310-321"},"PeriodicalIF":2.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38513992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent Patents and Advances on Nanotechnologies against Coronavirus.","authors":"Roozbeh Abedini-Nassab, Naeemeh Mahdaviyan","doi":"10.2174/1872210514666201110125536","DOIUrl":"https://doi.org/10.2174/1872210514666201110125536","url":null,"abstract":"<p><p>Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is one of the seven known coronaviruses infecting humans; HKU1, 229E, NL63, OC43, Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and SARS-CoV-2, the last three of which can cause severe symptoms in patients. COVID-19, previously known as 2019 novel coronavirus, caused by SARS-CoV-2, was first reported in Wuhan, China, in late 2019, and quickly resulted in a major epidemic across the world. Although the origin of SARS-CoV-2 is not clear yet, genome sequencing results suggest that this is the third reported spillover of an animal coronavirus to humans, from 2002. The development of detection, therapeutic, and prevention strategies for COVID-19 is a fundamental task towards curing infected people and competing with the pandemic. Because of their similarities, scientists believe that treatment/ detection methods similar to what were used against the illnesses caused by SARS-CoV or MERS-CoV may be effective for curing/detecting COVID-19. Here, we review the recent nanotechnology techniques used for treating and testing SARS-CoV, MERS-CoV, and SARS-CoV-2, and potential therapeutic options for curing COVID-19. This patent summarizes the recent findings of advances on Nanotechnologies against Coronavirus.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"15 4","pages":"322-330"},"PeriodicalIF":2.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38586657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent Advances on the Application of Graphene Quantum Dots in Energy Storage.","authors":"Feng Shi, Quanrun Liu","doi":"10.2174/1872210515666210120115159","DOIUrl":"https://doi.org/10.2174/1872210515666210120115159","url":null,"abstract":"<p><strong>Background: </strong>As an emerging carbon nanomaterial, Graphene Quantum Dots (GQDs) have shown great potential application in new energy storage devices due to their unique small size effect and abundant edge active sites. This work introduces the main synthesis strategies of GQDs, which include top-down and bottom-up methods; the application examples of GQDs and GQDsbased composites in energy storage are reviewed, moreover, the unique advantages of GQDs in supercapacitors, Lithium-Ion Batteries (LIBs) and Lithium-sulfur batteries (Li-S batteries) are highlighted. The problems and development prospects in this growing area are also discussed.</p><p><strong>Methods: </strong>We conducted a detailed search of \"the application of GQDs in energy storage devices\" in the published papers and the public patents based on the Web of Science database in the period from 2014 to 2020. The corresponding literature was carefully evaluated and analyzed.</p><p><strong>Results: </strong>Sixty papers and twenty-eight recent patents were included in this mini-review. The significant advances in recent years are summarized with comparative and balanced discussion. Thanks to the unique properties of large specific surface area, high conductivity and abundant active sites, GQDs have unparalleled potential application for new energy storage, especially improving the specific capacity and cycle stability of supercapacitors, LIBs and Li-S batteries.</p><p><strong>Conclusion: </strong>The findings of this mini-review confirm the importance of GQDs, show the enhanced electrochemical performance in supercapacitors, LIBs and Li-S batteries, and also provide a helpful guide to design and fabricate high-efficiency electrode materials.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"15 4","pages":"298-309"},"PeriodicalIF":2.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38864557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Overview of the Recent Developments and Patents in the Field of Pharmaceutical Nanotechnology.","authors":"Deepika Purohit, Deeksha Manchanda, Manish Makhija, Jyoti Rathi, Ravinder Verma, Deepak Kaushik, Parijat Pandey","doi":"10.2174/1872210514666200909154409","DOIUrl":"https://doi.org/10.2174/1872210514666200909154409","url":null,"abstract":"<p><strong>Background: </strong>Compared to traditional dosage methods, the Novel Drug Delivery Systems (NDDS) provide various advantages. In the last few years, the interest shifted to works focused on the novel drug delivery methods for small and large molecular drug carriers utilizing particulate drug delivery systems as well. It is evident from the last decade as observed in increased number of patents in this field that the technology has evolved tremendously.</p><p><strong>Objective: </strong>Drug carriers utilized by this novel technology include liposomes, dendrimers, polymeric nanoparticles, magnetic nanoparticles, solid lipid nanoparticles, and carbon nanomaterials. Various forms of polymers have been used in the production of nanocarriers.</p><p><strong>Methods: </strong>Nanocarriers are colloidal systems varying in size from 10 to 1000 nm. This technology is now used to identify, manage and monitor numerous diseases and physical methods to alter and enhance the pharmacokinetic and pharmacodynamic properties of specific types of drug molecules.</p><p><strong>Results: </strong>Nanoparticles can be formulated by a number of techniques including ionic gelation, crosslinking, coacervation/precipitation, nanoprecipitation, spray drying, emulsion- droplet coalescence, nano sonication techniques, etc. Several methods are used with which these nanoparticles can be characterized. These methods include nuclear magnetic resonance, optical microscopy, atomic force microscopy, photon correlation spectroscopy and electron microscopy, surface charge, in-vitro drug release, etc. Conclusion: In the present review, the authors have tried to summarize recent advances in the field of pharmaceutical nanotechnology and also focused on the application and new patents in the area related to NDDS.</p>","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"15 1","pages":"15-34"},"PeriodicalIF":2.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38364803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Conceptual Analysis of Solid Self-emulsifying Drug Delivery System and its Associate Patents for the Treatment of Cancer.","authors":"Neeraj Singh, Shweta Rai, Sankha Bhattacharya","doi":"10.2174/1872210514666200909155516","DOIUrl":"https://doi.org/10.2174/1872210514666200909155516","url":null,"abstract":"<p><strong>Background: </strong>About two-third of new drugs reveal low solubility in water due to which it becomes difficult for formulation scientists to develop oral solid dosage forms with a pharmaceutically acceptable range of therapeutic activity. In such cases, S-SMEEDS are the best carriers used universally for the delivery of hydrophobic drugs. SEDDS are also used but due to their limitations, SSMEDDS are used widely. These are the isotropic mixtures of oils, co-solvents, and surfactants. SSMEDDS are physically stable, easy to manufacture, easy to fill in gelatin capsules as well as improve the drug bioavailability by releasing the drug in the emulsion form into the gastrointestinal tract and enable smooth absorption of the drug through the intestinal lymphatic pathway.</p><p><strong>Methods: </strong>We conducted a literature search related to our review, also employing the peer-reviewed research, and provided a conceptual framework. Standard tools were used for drawing the figures of the paper, and various search engines were used for literature exploration. In this review article, the author has discussed the importance of S-SMEDDS, selection criteria for excipients, pseudo-ternary diagram, mechanism of action of S-SMEDDS, solidification techniques used for S-SMEDDS, Characterization of SEDDS and S-SMEDDS including Stability Evaluation of both and future prospects have been concluded through recent findings on S-SMEDDS in Cancer as well as a neoteric patent on S-SMEDDS.</p><p><strong>Results: </strong>Many research papers have been discussed in this review article, from which it was found that the ternary phase diagram is the most crucial part for developing the SMEDDS. From the various research findings, it was found that the excipient selection is the essential step which decides the strong therapeutic effect of the formulation. The significant outcome related to solid-SMEDDS is the less the globule size, the higher would be the bioavailability. The method in which adsorption of a solid carrier takes place is most widely used for the preparation of solid-SMEDDS. After reviewing many patents, it was observed that the solid-SMEDDS have a strong potential for targeting and treating different types of cancer due to their properties to enhance permeation and increase bioavailability.</p><p><strong>Conclusion: </strong>S-SMEEDS are more acceptable pharmaceutically as compared to SEDDS due to their various advantages over SEDDS, such as stability issue is prevalent with SEDDS. A number of patent researchers have formulated S-SMEDDS of poorly soluble drugs and found S-SMEDDS as prospective for the delivery of hydrophobic drugs in the treatment of cancer. S-SMEEDS are increasingly grabbing attention, and the patentability on S-SMEDDS is unavoidable, which proves that S-SMEEDS are widely accepted carriers. These are used universally for the delivery of hydrophilic drugs and anticancer drugs as they release the drug to the gastrointestinal tra","PeriodicalId":49324,"journal":{"name":"Recent Patents on Nanotechnology","volume":"15 2","pages":"92-104"},"PeriodicalIF":2.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38364802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}