纳米治疗法:纳米颗粒治疗法的制备及其在神经系统疾病治疗中的应用。

IF 2 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY
Astha Singh, Aakriti Patel, Hema Chaudhary, Kiran Yadav, Neha Minocha
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引用次数: 0

摘要

背景:治疗学是一种侧重于提供以患者为中心的护理的方法,并正在发展成为一种有针对性、安全和有效的药物治疗方法。纳米诊断学结合了诊断和治疗方式,将传统治疗和个性化医疗联系起来。治疗学为纳米技术提供了新的思路。这篇综述描述了目前用于治疗神经系统疾病的基于纳米技术的疗法的现状。本文还讨论了一些治疗学方面的专利。目的:本研究旨在对纳米治疗的诊断和治疗特性、基于纳米技术治疗神经系统疾病的现状以及纳米治疗的未来潜力进行更全面的综述。方法:“治疗学”一词是指将治疗学和诊断学相结合的治疗策略,以监测治疗反应并提高药物疗效和安全性。治疗学是个体化医疗的重要组成部分,需要在预测医学方面取得重大进展。术语“治疗学”是指根据测试结果筛选患者潜在的药物不良反应和靶向药物递送的诊断。治疗学治疗神经系统疾病(如脑肿瘤(神经胶质瘤)、帕金森氏病、阿尔茨海默病和神经血管疾病)。我们使用了Google Scholar、PubMed、Google Patents和Scopus上的许多评论文章来收集本综述的信息。本综述收集了来自许多来源的数据,以提供更多关于治疗学的信息。结果:在回顾了大量文献后,本文讨论了各种纳米载体系统在神经系统疾病治疗中的作用以及纳米材料的制备。结论:纳米颗粒具有独特的内在特性,可用于功能化和成像。核医学的治疗学包括诊断成像和使用不同放射性标记的同一分子或不同剂量的同一药物进行治疗。通过观察潜在靶点,可以确定病人是否会从某种治疗中获益。有针对性的核治疗已被证明是有益的,如果选择仔细,并具有良好的安全性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanotheranostics: The Fabrication of Theranostics with Nanoparticles and their Application to Treat the Neurological Disorders.

Background: Theranostics is a method that focuses on providing patient-centred care and is evolving as a targeted, safe, and effective pharmacotherapy. Nanotheranostics combines diagnosis and therapeutic modalities that bridge traditional treatment and personalised medicine. Theranostics provides novel ideas for nanotechnology. This review describes the current state of nanotechnology-based therapies used to treat neurological illnesses. Some patents on theranostics are also discussed in this review.

Objective: This study aims to provide a more comprehensive review of the diagnosis and therapeutic properties of nanotheranostics, the present state of nanotechnology-based treatment of neurological disorders, and the future potential of theranostics.

Method: The phrase "theranostics" refers to a treatment strategy that integrates therapeutics and diagnostics to monitor treatment response and enhance drug efficacy and safety. Theranostics is a crucial component of personalised medicine and calls for significant advancements in predictive medicine. The term "theranostics" refers to a diagnosis that screens patients for potential adverse drug reactions and targets drug delivery depending on the test results. Theranostics treats neurological disorders (like brain tumours (glioma), Parkinson's disease, Alzheimer's disease, and neurovascular diseases). Many review articles on Google Scholar, PubMed, Google Patents, and Scopus were used to gather information for this review. Data acquired from many sources was compiled in this review to provide more information on theranostics.

Result: The role of various nanocarrier systems as theranostic agents for neurological illnesses and the fabrication of nanomaterials for theranostics are discussed in this article after evaluating a substantial number of review articles.

Conclusion: The distinctive intrinsic features of nanoparticles make them useful for functionalization and imaging. Theranostics in nuclear medicine include diagnostic imaging and therapy using the same molecule that is radiolabeled differently or the same medication at various doses. It is possible to determine if a patient will benefit from a given treatment by visualising potential targets. Targeted nuclear therapy has been shown to be beneficial in patients if chosen carefully and has a good safety profile.

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来源期刊
Recent Patents on Nanotechnology
Recent Patents on Nanotechnology NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY
CiteScore
4.70
自引率
10.00%
发文量
50
审稿时长
3 months
期刊介绍: Recent Patents on Nanotechnology publishes full-length/mini reviews and research articles that reflect or deal with studies in relation to a patent, application of reported patents in a study, discussion of comparison of results regarding application of a given patent, etc., and also guest edited thematic issues on recent patents in the field of nanotechnology. A selection of important and recent patents on nanotechnology is also included in the journal. The journal is essential reading for all researchers involved in nanotechnology.
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