Daniel Y Kwon, Dillan F Villavisanis, Allison Choe, Nargiz Seyidova, Olachi Oleru, Peter Shamamian, Carol Wang, Alex Sarosi, Peter J Taub
{"title":"Complication Rates and Cost of Endoscopic and Open Surgical Approaches to Management of Craniosynostosis: A Large, National, Inpatient Cohort Evaluation.","authors":"Daniel Y Kwon, Dillan F Villavisanis, Allison Choe, Nargiz Seyidova, Olachi Oleru, Peter Shamamian, Carol Wang, Alex Sarosi, Peter J Taub","doi":"10.1177/10556656251320746","DOIUrl":"https://doi.org/10.1177/10556656251320746","url":null,"abstract":"<p><p>To compare outcomes, complications, and costs between endoscopic and open surgical approaches in the management of craniosynostosis using a large national database.</p><p><p>Retrospective cohort study.</p><p><p>National Inpatient Sample database, including inpatient hospital discharge data from 2018 to 2021 across 48 states and Washington, D.C.</p><p><p>The present study included 1099 patients admitted with a primary diagnosis of craniosynostosis. Among them, 183 (16.6%) underwent endoscopic surgery and 916 (83.3%) underwent open surgery.</p><p><p>Surgical management of craniosynostosis, classified as either an endoscopic or open approach.</p><p><p>Length of hospital stay, total procedure costs, and rates of inpatient complications, including surgical and medical complications.</p><p><p>Endoscopic surgery was associated with a significantly shorter length of stay (mean 1.6 days vs 3.7 days, <i>P</i> < .001) and lower total costs ($ 66 815.90 vs $ 146 271.21, <i>P</i> < .001) compared to open procedures. It demonstrated lower rates of surgical complications (0.5% vs 7.9%, <i>P</i> < .001) and neurologic complications, primarily dural tears (0.5% vs 7.0%, <i>P</i> < .001). There were no differences in inpatient mortality between groups.</p><p><p>Endoscopic approaches to craniosynostosis offer advantages over open techniques, including reduced length of stay, costs, and complications. The present findings support the increasing adoption of endoscopic methods for craniosynostosis management. Future studies should assess the long-term impact on head shape durability and neurodevelopmental outcomes.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251320746"},"PeriodicalIF":1.1,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan H Belcher, Krishna Patel, Jackie Clark, Sara Horne
{"title":"Addressing Cleft Care in Low- and Middle-Income Countries Beyond Cleft Lip and Palate with Improvement of Otolaryngology, Audiology, and Speech Services.","authors":"Ryan H Belcher, Krishna Patel, Jackie Clark, Sara Horne","doi":"10.1177/10556656251319649","DOIUrl":"https://doi.org/10.1177/10556656251319649","url":null,"abstract":"<p><p>There are many barriers patients and families face in low- and middleincome countries (LMICs) to just receive the initial surgical care for their cleft lip and palate (CLP). Cleft lip/palate care encompasses much more than just the initial primary repairs, especially in the realm of otolaryngology, audiologic health, and speech language pathology. LMICs face many disparities in training and surgical care for secondary cleft surgeries, and addressing these disparities and creating solutions is paramount for the future of CLP patients globally. This editorial aims to highlight these disparities and pave a path forward with solution-based discussions.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251319649"},"PeriodicalIF":1.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Batol K Alattar, Anthony J Ireland, Jonathan R Sandy, Peter V Fowler
{"title":"Dental Arch Relationship Outcomes of 5-Year-Olds Born With Unilateral Cleft Lip and Palate Following the Centralization of Cleft Services.","authors":"Batol K Alattar, Anthony J Ireland, Jonathan R Sandy, Peter V Fowler","doi":"10.1177/10556656251322610","DOIUrl":"https://doi.org/10.1177/10556656251322610","url":null,"abstract":"<p><p>To investigate the interdental arch relationship outcomes of 5-year-old children with unilateral cleft lip and palate (UCLP) before and after centralization of cleft services in the United Kingdom (UK) using the modified Huddart-Bodenham index (MHBI) and to investigate any differences in MHBI by cleft laterality.</p><p><p>Retrospective cross-sectional study.</p><p><p>Evaluation of three-dimensional study models of children with a complete UCLP.</p><p><p>All available 5-year-old orthodontic study models of participants with UCLP from the precentralization Clinical Standard Advisory Group (CSAG <i>n</i> = 107) and postcentralization cleft care UK (CCUK <i>n</i> = 195) studies. The models were also grouped by cleft laterality (left and right sided).</p><p><p>Differences between the interdental arch relationship outcomes were assessed using the MHBI. This index scored the buccal/palatal or labial/palatal relationships of 8 maxillary deciduous teeth with the opposing mandibular dentition. The anterior segment, buccal cleft segment, and noncleft segment scores were calculated and combined to calculate the MBHI total arch scores.</p><p><p>Inter and intraexaminer reliability demonstrated high levels of agreement. Statistically significant differences in the anterior segment, buccal noncleft segment, and total arch MHBI scores were found, with postcentralization CCUK performing better. Right-sided UCLP had statistically significantly better buccal cleft segments, but no differences were found for the other MBHI segments or total arch scores.</p><p><p>There were improved interdental arch relationships postcentralization of cleft services in the United Kingdom. Cleft laterality differences were limited to the buccal cleft segment with right-sided UCLP having better MBHI scores.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251322610"},"PeriodicalIF":1.1,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143460349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gozel Jumayeva, Merve Soğukpınar, Beren Karaosmanoğlu, Gizem Ürel-Demir, Rahşan Göçmen, Gülen Eda Utine, Pelin Özlem Şimsek-Kiper
{"title":"ERF-Related Craniosynostosis in a Patient With Hypochondroplasia: A Case Report.","authors":"Gozel Jumayeva, Merve Soğukpınar, Beren Karaosmanoğlu, Gizem Ürel-Demir, Rahşan Göçmen, Gülen Eda Utine, Pelin Özlem Şimsek-Kiper","doi":"10.1177/10556656251319644","DOIUrl":"https://doi.org/10.1177/10556656251319644","url":null,"abstract":"<p><p>We report a case of multiple suture craniosynostosis in a patient with hypochondroplasia. The patient presented with short stature marked by a relatively long trunk and short extremities. The clinical and radiological findings were suggestive of hypochondroplasia. Additionally, craniosynostosis was identified during the evaluation, which is an unusual finding in hypochondroplasia. To further investigate, exome sequencing was performed, revealing previously reported pathogenic heterozygous variants in <i>FGFR3</i> and <i>ERF</i> genes. Exome sequencing not only enhances the accuracy of diagnosing individual cases of genetic skeletal disorders but also contributes to the collective knowledge base, advancing future research in the field.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251319644"},"PeriodicalIF":1.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Use of Fixed and Removable Bite Blocks in Bilateral Buccinator Flap Surgery for Velopharyngeal Insufficiency.","authors":"Lucy Coull, Mary Bussell, Nefer Fallico","doi":"10.1177/10556656251314257","DOIUrl":"https://doi.org/10.1177/10556656251314257","url":null,"abstract":"<p><p>To ascertain the current practice in the United Kingdom with regard to the use of bite blocks and the division of the pedicles in buccinator flap surgery for velopharyngeal insufficiency. To compare the outcomes of fixed and removable bite blocks in buccinator flap surgery, in terms of the incidence of pedicle injury and patient experience.</p><p><p>Survey of cleft surgeons in the United Kingdom on their use of bite blocks and division of the pedicles. Retrospective cohort review of consecutive patients that underwent buccinator flap surgery at Salisbury District Hospital between January 1, 2021, and December 31, 2022, comparing the use of fixed and removable bite blocks. Survey of patients who had bite blocks fitted to understand the patient and family experience.</p><p><p>Cleft consultants from the United Kingdom and Ireland responded: half (11 of 22) reported using bite blocks and half reported routinely dividing the pedicles, most commonly at 4 to 6 weeks after surgery. In our cohort (19 patients), fixed bite blocks had a higher incidence of pedicle injury (33%) and difficulty eating (78%) than removable bite blocks (20% and 20%, respectively). Generally, parents/patients tolerated the presence of bite blocks and were often unaware of pedicle injury, even in cases of repeated severe biting.</p><p><p>There is variation in the current use of bite blocks and pedicle division following buccinator flap surgery in the United Kingdom. In compliant patients, removable bite blocks may be associated with lower complication rates but neither fixed nor removable bite blocks compromise flap integrity.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251314257"},"PeriodicalIF":1.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Family-Centered Care by Parents and Nurses of Children With Congenital Microtia.","authors":"Kexin He, Na Liu, Jiayan Gou, Yao Feng, Yang Li","doi":"10.1177/10556656251319643","DOIUrl":"https://doi.org/10.1177/10556656251319643","url":null,"abstract":"<p><strong>Background: </strong>The family-centered care is widely applied in pediatric nursing; however, there has been no research reflecting its extent of practice in the auricular reconstruction process for families of children with congenital microtia in China.</p><p><strong>Objective: </strong>This study aims to understand the perspectives of parents of children with congenital microtia and nurses at auricular reconstruction centers in Beijing, China, regarding family-centered care practices and specific areas that need improvement.</p><p><strong>Methods: </strong>The study utilized the Measure of Processes of Care (MPOC-20) and the Measure of Processes of Care for Service Providers (MPOC-SP) to survey 100 parents and 22 nurses. Scores for each dimension and item with low score (1-4 points, representing for at least 25% respondents) were statistically analyzed, indicated deficiencies in care services. The scores of parents and nurses were compared with international data.</p><p><strong>Results: </strong>In this study, the dimension scores of the MPOC-20 ranged from 5.34 ± 1.22 (Coordinated and Comprehensive Care) to 5.57 ± 1.22 (Providing Specific Information). The dimension scores of the MPOC-SP ranged from 5.91 ± 1.08 (Showing Interpersonal Sensitivity) to 6.25 ± 1.20 (Providing General Information). Both sets of scores were higher than most previous studies, particularly in Providing General Information.</p><p><strong>Conclusion: </strong>Parents of children with congenital microtia and nurses generally rated family-centered care practices positively. However, improvements are needed in Coordinated and Comprehensive Care and Showing Interpersonal Sensitivity. Future efforts should aim to enhance the care system for microtia by standardizing care service content, increasing auditory and psychological interventions, and strengthening long-term follow-up care.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251319643"},"PeriodicalIF":1.1,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Zygomatic Implant Rehabilitation in Patients With Cleft Lip and Palate: A Narrative Review of Clinical Outcomes and Indication Criteria Validation.","authors":"Bhárbara Marinho Barcellos, Shengchi Fan, Bilal Al-Nawas, Peer Kämmerer, Julia Heider","doi":"10.1177/10556656251318854","DOIUrl":"https://doi.org/10.1177/10556656251318854","url":null,"abstract":"<p><p>Zygomatic implant (ZI) is considered a predictable alternative for patients with atrophic maxilla. However, regarding the case of patients with cleft lip and palate (CLP), the evidence of ZI rehabilitation remains unclear. This study aimed to evaluate the indications and clinical outcomes of rehabilitation using ZI in CLP patients. The focus question was: \"What are the indications and clinical outcomes of ZI rehabilitation in patients with CLP?\" Electronic and manual literature searches were performed from January 2000 to May 2024 in five databases. Clinical studies and case reports were selected. The primary outcome was the ZI survival rates. The secondary outcomes were indications, loading protocols, and complications. The extracted data were subjected to descriptive analysis. In total, 16 studies were included, 24 patients with CLP received 48 ZIs, with an average of 4.2 years of follow-up. The survival rate of ZIs was 97.9% and was mainly indicated for those with Cawood and Howell classification V and VI, with insufficient bone in the maxilla with bilateral CLP. The immediate loading was performed in 33.3% of the cases, and the prosthesis was designed according to case complexity and necessity. ZI rehabilitation appears to be a reliable and predictable solution for the patient with CLP. The immediate loading solution can be beneficial to CLP patients as it helps avoid additional treatments. However, with the inconsistently limited data, the indications cannot be only based on the existing CLP classification.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251318854"},"PeriodicalIF":1.1,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Maxillary Sinus Pathologies in Children and Adolescents with Cleft Lip and Palate Using Cone Beam Computed Tomography: A Retrospective Study.","authors":"Ayşe Çelik, Nilüfer Ersan, Senem Selvi-Kuvvetli","doi":"10.1177/10556656241306834","DOIUrl":"https://doi.org/10.1177/10556656241306834","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to evaluate maxillary sinus (MS) pathologies in children and adolescents with cleft lip and palate (CLP) in comparison to a sex- and age-matched control group using cone beam computed tomography (CBCT), retrospectively.</p><p><strong>Method: </strong>CBCT images obtained between the years 2014 and 2022 from a total of 130 patients aged between 7 and 18 were considered eligible for this study. Age, sex, and the type of MS pathologies in each sinus were recorded in CLP (n = 65) and control (n = 65) groups. The MS pathologies were categorized and recorded for both right and left sinuses separately as: (1) healthy; (2) mucosal thickening >3 mm; (3) polypoidal mucosal thickening; (4) partial opacification; and (5) complete opacification. In the CLP group, the cleft type and side were also recorded. Variations of polypoidal mucosal thickenings were subcategorized as small, large, and multiple.</p><p><strong>Results: </strong>The mean age of the 130 patients (58 female, 72 male) was calculated as 12.43 ± 3.13. Among the patients in the study and control groups, polypoidal mucosal thickening was found to be the most frequent sinus pathology (25.4%), while total opacification was found to be the least frequent (1.6%). Overall, only the number of sinuses with mucosal thickening greater than 3 mm was statistically significantly higher in the CLP than that of the control group (<i>P</i> < .05). In terms of cleft type and side, the frequency of the pathology based on the sinuses showed no significant difference in any of the pathology groups (<i>P</i> > .05).</p><p><strong>Conclusion: </strong>Incidental findings in the oral and maxillofacial region that are detected on CBCT images of CLP patients may play an important role in the early diagnosis of MS diseases and aid in the referral for further evaluation.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241306834"},"PeriodicalIF":1.1,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fo Yew Tan, Nor Adilah Binti Mohd Nor, Siti Fauzza Ahmad, Firdaus Hariri
{"title":"Utilization of Mandibular Occlusal Plane as Vector Guidance Oral Prosthesis in Cleft Maxillary Distraction Osteogenesis: A Technical Note.","authors":"Fo Yew Tan, Nor Adilah Binti Mohd Nor, Siti Fauzza Ahmad, Firdaus Hariri","doi":"10.1177/10556656251319642","DOIUrl":"https://doi.org/10.1177/10556656251319642","url":null,"abstract":"<p><strong>Background: </strong>Conventionally, vector guidance for internal distractor placement during cleft maxillary distraction osteogenesis (DO) is done using vector guidance splint. Vector guidance splint cannot be fabricated if occlusion is not decompensated for model surgery.</p><p><strong>Solution: </strong>Using mandibular occlusal plane as anatomical reference, vector guidance oral prosthesis is fabricated to guide distractor placement and vector determination, in cases where model surgery is not possible.</p><p><strong>What we do that is new: </strong>Vector guidance oral prosthesis is a new prototype produced to guide maxillary DO without the need of model surgery.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251319642"},"PeriodicalIF":1.1,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karthik Sennimalai, Kaja Mohaideen, Madhanraj Selvaraj, Hamza Parvez Siddiqui, Om Prakash Kharbanda, Sakshi Katyal
{"title":"Cephalometric Parameters as Predictive Factors for Orthognathic Surgery in Unilateral Cleft Lip and Palate Patients: A Systematic Review and Meta-Analysis.","authors":"Karthik Sennimalai, Kaja Mohaideen, Madhanraj Selvaraj, Hamza Parvez Siddiqui, Om Prakash Kharbanda, Sakshi Katyal","doi":"10.1177/10556656251316967","DOIUrl":"https://doi.org/10.1177/10556656251316967","url":null,"abstract":"<p><p>To identify cephalometric parameters that could predict future need for orthognathic surgery (OGS) in patients with unilateral cleft lip and palate (UCLP).</p><p><p>Final search was conducted on July 7, 2024, across PubMed, Scopus, Embase, Web of Science, Cochrane, Ovid Medline, EBSCO, and LILACS, without any language and publication time restriction. Studies comparing surgical versus nonsurgical UCLP patients were included. Two independent reviewers screened studies, and those included were evaluated using Quality in Prognostic Studies (QUIPS) tool. Random-effects meta-analysis of various sagittal and vertical cephalometric parameters (SNA, SNB, ANB, mandibular plane angle [MPA], and lower anterior face height [%LFH]) was performed.</p><p><p>Ten studies were included in systematic review and 5 in meta-analysis. Quality in Prognostic Studies tool assessment indicated moderate risk in 6 studies, with 2 demonstrating high and low risks of bias. Meta-analysis revealed that in the 5- to 8-year age group, significant differences were observed in SNA and ANB angles between surgical and nonsurgical groups, with mean differences of 2.25° (95% confidence interval [CI] = 1.12, 3.39) and 3° (95% CI = 1.86, 4.15), respectively. In 9- to 14-year age group, significant differences were found in all 3 sagittal parameters: SNA angle difference of 2.65° (95% CI = 1.44, 3.86), SNB angle difference of 3.23° (95% CI = -4.69, -1.77), and ANB angle difference of 5.54° (95% CI = 3.66, 7.42). Vertical parameters (MPA and %LFH) were not statistically significant between groups in any age group.</p><p><p>Cephalometric parameters could be a valuable predictive factor for determining the future need for OGS in patients with UCLP. ANB angle has been shown to be a significant predictor for distinguishing between surgical and nonsurgical patients.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251316967"},"PeriodicalIF":1.1,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}