Esra Ekizer, Kevser Kurt Demirsoy, Süleyman Kutalmış Büyük, Semih Canpolat, Ahmet Bilirer
{"title":"Comparative Evaluation of ChatGPT-4o and Grok-3 on Cleft Lip and Palate and Presurgical Infant Orthopedics: A Multidisciplinary Assessment by Orthodontists, Pediatricians, and Plastic Surgeons.","authors":"Esra Ekizer, Kevser Kurt Demirsoy, Süleyman Kutalmış Büyük, Semih Canpolat, Ahmet Bilirer","doi":"10.1177/10556656251378591","DOIUrl":"https://doi.org/10.1177/10556656251378591","url":null,"abstract":"<p><p><b>Objective:</b> This study aimed to evaluate and compare the accuracy, clarity, and clinical applicability of 2 state-of-the-art large language models (LLMs), Chat Generative Pretrained Transformer (ChatGPT)-4o and Grok-3, in generating health information related to cleft lip and palate (CLP) and presurgical infant orthopedics (PSIO). To ensure a multidisciplinary perspective, experts from orthodontics, pediatrics, and plastic surgery independently evaluated the responses. <b>Methods:</b> Six structured questions addressing general and presurgical aspects of CLP were submitted to both ChatGPT-4o and Grok-3. Forty-five blinded specialists (15 from each specialty) assessed the 12 generated responses using 2 validated instruments: the DISCERN tool and the Global Quality Scale (GQS). We conducted interspecialty comparisons to explore variations in model evaluation. <b>Results:</b> We observed no statistically significant differences between ChatGPT-4o and Grok-3 in DISCERN or GQS scores (<i>P</i> > .05). However, pediatricians consistently assigned higher ratings than orthodontists and plastic surgeons in terms of reliability, clarity, and treatment-related content. Patient-directed questions received higher overall scores than those aimed at healthcare professionals. Grok-3 performed slightly better on questions about PSIO, whereas ChatGPT-4o provided more comprehensive and structured answers. <b>Conclusion:</b> Both LLMs demonstrated notable potential in producing readable, informative responses about CLP and PSIO. While they may aid in patient communication and support clinical education, professional oversight remains critical to ensure medical accuracy. The inclusion of Grok-3 in this orthodontic evaluation provides valuable insights and sets the stage for future research on artificial intelligence integration in interdisciplinary cleft care.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251378591"},"PeriodicalIF":1.3,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberta Costa E Silva, Felicia Miranda, Shana Rufino, Terumi Okada Ozawa, Gabriela Neves de Castro, Daniela Garib, José Fernando Castanha Henriques
{"title":"Facial Growth in Patients With Bilateral Cleft Lip and Palate After two-Stage Palatoplasty Using Vomer Flap.","authors":"Roberta Costa E Silva, Felicia Miranda, Shana Rufino, Terumi Okada Ozawa, Gabriela Neves de Castro, Daniela Garib, José Fernando Castanha Henriques","doi":"10.1177/10556656251376513","DOIUrl":"https://doi.org/10.1177/10556656251376513","url":null,"abstract":"<p><p>ObjectiveThis study aimed to assess the impact of two-stage palatoplasty incorporating a vomer flap on facial growth of individuals with bilateral cleft lip and palate (BCLP).SettingHospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, Brazil.DesignA cross-sectional study involving patients who underwent labial adhesion and anterior palatoplasty with a vomer flap at 3 and 5 months, followed by posterior palatoplasty at 12 months. Individuals without prior orthodontic treatment or secondary alveolar bone grafting were included. Cephalometric radiographs were obtained during mixed or early permanent dentition. A control group of untreated class I individuals without clefts was evaluated.ParticipantsThe sample comprised 49 individuals with BCLP (17 females, 32 males; mean age 8.91 years) and 44 control subjects (17 females, 27 males; mean age 8.91 years).Main Outcome MeasureCephalometric analysis was conducted using Dolphin Imaging software (version 11.95). Intergroup comparisons were performed using independent t-tests and Mann-Whitney U tests (<i>P</i> < .05).ResultsNo significant difference between groups was found in maxillary sagittal position. However, BCLP group showed a significantly smaller SNB angle (mean difference -2.1°, <i>P</i> < .003) and a more convex skeletal profile compared to the noncleft group. Additionally, BCLP group exhibited severe lingual inclination of the maxillary incisors, (MD = -31.6°, <i>P</i> < .001) and a high prevalence of anterior crossbite.ConclusionAt the time of observation, the maxillary sagittal position appeared comparable between groups. However, mandibular retrusion contributed to a more convex profile. The severe retroinclination of maxillary incisors determined a negative overjet. Longitudinal follow up are needed to confirm long-term maxillofacial growth outcomes.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251376513"},"PeriodicalIF":1.3,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hanna Sepsick, Boyu Ma, Shane Yann Chang Kau, Kathlyn Powell, Chung H Kau
{"title":"Simultaneous Le Fort III and Le Fort I Osteotomies for Rare Midfacial Hypoplasia in a Patient with 15q11.2 Microdeletion-A Multidisciplinary Approach.","authors":"Hanna Sepsick, Boyu Ma, Shane Yann Chang Kau, Kathlyn Powell, Chung H Kau","doi":"10.1177/10556656251376904","DOIUrl":"https://doi.org/10.1177/10556656251376904","url":null,"abstract":"<p><p>15q11.2 microdeletion syndrome, also known as Burnside-Butler syndrome, is a rare partial autosomal monosomy associated with a spectrum of neurodevelopmental, cognitive, and behavioral disorders. Due to its atypical occurrence and limited research, craniofacial manifestations linked to this microdeletion remain poorly documented. This study presents a novel case of severe midface hypoplasia in a patient with 15q11.2 microdeletion syndrome, treated with a 2-stage surgical approach, and a review of the literature for simultaneous Le Fort III/I osteotomies. The first phase involved simultaneous Le Fort III and Le Fort I osteotomies followed by midface distraction, while the second phase included orthodontic treatment and a subsequent Le Fort I and bilateral sagittal split osteotomy. This report highlights the complexity of managing craniofacial anomalies in this syndrome and underscores the importance of a multidisciplinary approach for optimal outcomes.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251376904"},"PeriodicalIF":1.3,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Relationship Between Nasal Function and Lung Function in Adults with Cleft lip and Palate and Dentofacial Deformity.","authors":"Ana P Dias, Karine A Arruda, Ana P Fukushiro","doi":"10.1177/10556656251372332","DOIUrl":"https://doi.org/10.1177/10556656251372332","url":null,"abstract":"<p><p>ObjectiveTo verify the relationship between nasal function, nasal patency, respiratory mode, and type and lung function through lung capacity in patients with cleft lip and palate (CLP).ProjectQuantitative and cross-sectional clinical research.ContextTertiary-level craniofacial hospital.ParticipantsThirty patients between 18 and 30 years old with repaired CLP and presence of dentofacial deformity were evaluated.InterventionsThe respiratory mode and type were determined through perceptive assessment and obtaining respiratory symptoms, through a self-reported questionnaire. Spirometry and rhinomanometry were applied.Main outcome measuresForced vital capacity and peak forced expiratory flow.ResultsIt was identified that the respiratory mode directly influences peak expiratory flow (PEF) values, as well as the presence of respiratory disease. Forced vital capacity (FVC) showed a statistically significant relationship (<i>p</i> = .036), decreasing its values with the presence of self-reported nasal obstruction. By rhinomanometry, an average of 0.537 (±140 cm²) was obtained for nasal cross-sectional area values, with only 7.69% of cases with values below 0.400 cm², suggesting nasal obstruction.ConclusionThere is a relationship between nasal and pulmonary function in patients with CLP, with regard to the respiratory mode, presence of respiratory disease and self-reported nasal obstruction, influencing lung capacity values such as FVC and PEF.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251372332"},"PeriodicalIF":1.3,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bach Kim Nguyen, Camila Caro, Kyle Stevens, Gabriella A Garisto, Yoav Finer
{"title":"Computer-Aided Design and Computer-Aided Manufacturing Technology for Conducting Nasoalveolar Molding for Infants With Cleft Lip and Palate: A Scoping Review.","authors":"Bach Kim Nguyen, Camila Caro, Kyle Stevens, Gabriella A Garisto, Yoav Finer","doi":"10.1177/10556656251363400","DOIUrl":"https://doi.org/10.1177/10556656251363400","url":null,"abstract":"<p><p>ObjectiveTo identify, describe, and characterize computer-aided design and computer-aided manufacturing (CAD/CAM) methods for nasoalveolar molding (NAM) based on a structured search of scientific literature.DesignScoping review was conducted following the PRISMA-ScR guidelines. Searches were done in MEDLINE, Embase, Web of Science, Cochrane Library, and Scopus. Screening and data extraction were performed.PatientsInfants with unrepaired, nonsyndromic, complete unilateral cleft lip and palate (UCLP), or bilateral cleft lip and palate (BCLP).InterventionCAD/CAM NAM.Main Outcome MeasuresOutcome measures were the digitization, virtual modeling, and manufacturing protocols.ResultsThirteen articles were included. CAD/CAM NAM involved digitizing the maxilla, designing step-by-step (stepwise) alveolar movements or expansion of plates, then manufacturing plates manually or through 3D printing. Four methods were characterized based on the virtual modeling and manufacturing techniques employed: stepwise alveolar molding and manually fabricated plates (SM_MP); stepwise alveolar molding and 3D-printed plates (SM_3P); stepwise plate expansion and 3D-printed plates (SPE_3P); and semi-automated plate expansion and 3D-printed plates (SAPE_3P). The SM_MP method was the most common, followed by the SM_3P, SPE_3P, and SAPE_3P methods. All methods were applied to treat infants with UCLP, whereas only the SM_MP and SM_3P methods were used for infants with BCLP.ConclusionsThis scoping review provides an overview of 4 CAD/CAM methods for NAM. The SM_MP and SM_3P methods simulate alveolar molding; however, the SM_3P method exhibits more advanced design and manufacturing of plates. The SPE_3P and SAPE_3P methods design consecutively enlarged plates, with the latter employing a semi-automated protocol.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251363400"},"PeriodicalIF":1.3,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shenhu Liang, Yuxiang Zai, Zhongwei Chen, Jing Yang, Xin Shu, Jianmin Luo, Nan Wang, Fang Wang, Qinggao Song
{"title":"A Preliminary Study of the Relationship Between Zinc and the AhR Signaling Pathway During Palatal Development.","authors":"Shenhu Liang, Yuxiang Zai, Zhongwei Chen, Jing Yang, Xin Shu, Jianmin Luo, Nan Wang, Fang Wang, Qinggao Song","doi":"10.1177/10556656251375952","DOIUrl":"https://doi.org/10.1177/10556656251375952","url":null,"abstract":"<p><p>ObjectiveTo investigate the effects of zinc concentration on palatal development in fetal mice and its association with the aryl hydrocarbon receptor (AhR) signaling pathway.MethodsPregnant C57BL/6J mice were fed diets with varying zinc concentrations and randomly divided into a zinc-rich (ZR) group, a normal-zinc (NZ) group, and a zinc-deficient (ZD) group. Embryonic development was observed, and the expression levels of AhR signaling pathway-related factors were examined.ResultsNo cleft palate was observed in the ZR group or NZ group, whereas the zinc-deficient group exhibited a cleft palate incidence of 27.45%. Hematoxylin and Eosin (HE) staining results revealed failed palatal shelf contact and fusion in the ZD group, whereas complete fusion occurred in the ZR group and a normal medial edge epithelial formed in the NZ group. Results from Immunohistochemistry (IHC), qRT-PCR, and Western blot analyses collectively demonstrated that, compared to the NZ group, the ZR group exhibited significant upregulation (<i>P</i> < .05) in both mRNA and protein expression levels of AhR, HSP90, CYP1A1, and SP1, whereas the ZD group displayed significant downregulation (<i>P</i> < .05).ConclusionZinc concentration is intimately correlated with fetal mouse palatal development, where zinc deficiency may contribute to cleft palate formation through suppression of AhR signaling pathway, whereas zinc-rich conditions facilitate activation of this pathway. This study reveals the regulatory role of zinc-AhR signaling axis in palatal development through mouse models, offering novel theoretical insights into zinc deficiency-induced cleft palate pathogenesis and establishing a foundational framework for preventive interventions.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251375952"},"PeriodicalIF":1.3,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Homero Carneiro Aferri, Olivia Mesquita Vieira de Souza, Monica Moraes Waldemarin Lopes, Jeniffer de Cássia Rillo Dutka, Maria Inês Pegoraro-Krook
{"title":"Pharyngeal Bulb Reduction Program in Individuals with Cleft Palate.","authors":"Homero Carneiro Aferri, Olivia Mesquita Vieira de Souza, Monica Moraes Waldemarin Lopes, Jeniffer de Cássia Rillo Dutka, Maria Inês Pegoraro-Krook","doi":"10.1177/10556656251370490","DOIUrl":"https://doi.org/10.1177/10556656251370490","url":null,"abstract":"<p><p>ObjectivesTo describe a pharyngeal bulb reduction program (PBRP) aimed at decreasing the size of the velopharyngeal gap in individuals with repaired cleft palate presenting hypodynamic velopharynx, and to evaluate the effect of the PBRP on pharyngeal bulb dimensions.MethodsThirteen patients (6 females and 7 males; mean age = 28 years) with repaired cleft palate and hypodynamic velopharynx, who demonstrated normal speech using a pharyngeal bulb, participated in the study. The PBRP lasted two weeks and consisted of sequential pharyngeal bulb reductions during nasoendoscopy combined with intensive speech therapy. After each bulb reduction, measurements of bulb length, width, area, volume, and the prosthesis weight (pre-/post-PBRP) were obtained.ResultsAt the end of the PBRP, reductions in bulb dimensions were observed (length: -32.13%, width: -47.26%, area: -61.41%, and volume: -52.80%), as well as a decrease in prosthesis weight (-21.12%).Conclusions\"In PBRB, the reduction in the dimensions of the pharyngeal bulb, combined with intensive speech therapy, proved effective in stimulating velopharyngeal mechanism movements during speech, leading to a consequent reduction in the size of the velopharyngeal gap. Following the PBRB procedure, reductions in the width and length of the bulb were observed, creating more favorable conditions for performing secondary surgery aimed at correcting velopharyngeal insufficiency.\"</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251370490"},"PeriodicalIF":1.3,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paul Asadourian, Alyssa B Valenti, Alexandra Michalowski, Albert Y Truong, Nell Borys, Myles LaValley, Vikash Modi, Thomas A Imahiyerobo
{"title":"Estimated Time of Arrival: Impact of Healthcare Disparities on Access to and Outcomes of Multidisciplinary Cleft Lip and Palate Care.","authors":"Paul Asadourian, Alyssa B Valenti, Alexandra Michalowski, Albert Y Truong, Nell Borys, Myles LaValley, Vikash Modi, Thomas A Imahiyerobo","doi":"10.1177/10556656241259890","DOIUrl":"10.1177/10556656241259890","url":null,"abstract":"<p><p>ObjectiveTo determine the impact of sociodemographic and clinical factors on patient presentation into the cleft care pathway and determine how delayed interventions may affect post-surgical outcomes.DesignRetrospective study.SettingMultidisciplinary craniofacial clinics of two university hospitals.Patients, Participant135 patients with cleft lip and/or palate.InterventionsPrimary cheiloplasty, primary palatoplasty.Main Outcome MeasuresAge at initial presentation, age at first surgery, lag time, delayed surgery, rate of return to the emergency department (ED), readmission rate, reoperations, and oronasal fistula development.ResultsPatients referred by OBGYN who underwent cheiloplasty had an earlier age at initial presentation (p < 0.01), earlier age at first surgery (p = 0.01), and a shorter lag time (p < 0.01) compared to children from other referral pathways. African American children had an older age at first surgery (p = 0.01) and a longer lag time (p = 0.02) when compared to non-African American children. Children with syndromes had an older age at first surgery (p < 0.01) and a longer lag time (p < 0.01) than children without syndromes. Patient race, cleft type, and syndromic status increased the odds of receiving delayed surgery. Patients who received delayed palatoplasty returned to the ED at a higher rate than patients who received non-delayed palatoplasty (p = 0.02).ConclusionsOur data suggest that referral source, race, and syndromic status influence the timeliness of cleft care. Surgeons should develop strong referral networks with local OBGYNs and hospitals to allow for an early entry into the cleft care pathway.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1461-1468"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141735453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juliana Garcia Martins, Pâmella de Oliveira Ladeia, Roseli Maria Zechi-Ceide, Mariani da Costa Ribas, Nicolle Zimmermann, Luciana Paula Maximino
{"title":"Cognitive and Behavioral Characteristics of Children with Robin Sequence Associated with Stickler Syndrome: A Case Series.","authors":"Juliana Garcia Martins, Pâmella de Oliveira Ladeia, Roseli Maria Zechi-Ceide, Mariani da Costa Ribas, Nicolle Zimmermann, Luciana Paula Maximino","doi":"10.1177/10556656251372323","DOIUrl":"https://doi.org/10.1177/10556656251372323","url":null,"abstract":"<p><p>This study describes the cognitive and behavioral characteristics of five children with Robin Sequence associated with Stickler Syndrome. All showed preserved intelligence, with most scoring within the average range for working memory, verbal inhibition, visuospatial planning, and auditory attention. Visual attention difficulties were noted. Two had academic deficits. Four children showed symptoms of Attention-Deficit/Hyperactivity Disorder (ADHD), and one was diagnosed with ADHD and Specific Learning Disorder, also presenting signs of Obstructive Sleep Apnea. Findings highlight the need for systematic, multidisciplinary follow-up, emphasizing sleep-related respiratory evaluation as a differential diagnosis for inattention, hyperactivity, and academic difficulties.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251372323"},"PeriodicalIF":1.3,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144975919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Osseous Outcomes of Cleft Alveolar Bone Grafting with Allograft and Platelet-Rich Fibrin: Preliminary Study with Radiological Outcome.","authors":"Julie Chauvel-Picard, Camille Lambert, Dominique Gaget, Marc Asselborn, Edouard Lange, Arnaud Gleizal","doi":"10.1177/10556656241271663","DOIUrl":"10.1177/10556656241271663","url":null,"abstract":"<p><p>ObjectiveCleft lip and palate are the most common craniofacial malformations worldwide. The alveolar cleft is treated with a bone graft, between 4 and 7 years of age in mixed dentition. This is an important step because it provides good quality jawbone and a better support of the lip and the alar cartilage on the side of the cleft. Bone autografting with iliac harvesting remains the most commonly used technique, but it is not without risks. Allograft techniques have therefore been described to reduce this morbidity (pain, infectious risk, hemorrhagic risk, fracture risk). The aim of this study was to evaluate, one year after allografting, the efficiency and consolidation of the bone allograft in the alveolar cleft.SettingA retrospective study was conducted in the department of pediatric craniomaxillofacial surgery in the Woman-Mother-Child Hospital in Lyon, France.PatientsThis series includes 22 patients or 25 alveolar cleft bone grafts, including 16 boys and 6 girls, with an average age of 6.1 years.Main Outcome MeasuresQuantify the residual bone allograft by evaluating the ratio between the volume of the bone graft and the volume of the initial space on pre- and post-operative cone beam computed tomography.ResultsThe residual bone allograft percentage at 1 year was 58.5% (± 22.3).ConclusionsAlveolar cleft bone graft with bone allograft is an alternative to iliac autografting to reduce donor site morbidity.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1549-1554"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}