Cleft Palate-Craniofacial Journal最新文献_第8页

Pilot Study Evaluating Augmented Reality Craniotomy Guides for Fronto-Orbital Advancement. 评估增强现实开颅指导额眶前进的初步研究。

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 DOI: 10.1177/10556656251355791

David L Best, Jessica G Li, Vicky Yau, Charles Gattie, Larson Hsu, Renée M Reynolds, Thomas M Zervos, Michael R Markiewicz

{"title":"Pilot Study Evaluating Augmented Reality Craniotomy Guides for Fronto-Orbital Advancement.","authors":"David L Best, Jessica G Li, Vicky Yau, Charles Gattie, Larson Hsu, Renée M Reynolds, Thomas M Zervos, Michael R Markiewicz","doi":"10.1177/10556656251355791","DOIUrl":"https://doi.org/10.1177/10556656251355791","url":null,"abstract":"ObjectiveAugmented reality (AR) has recently emerged as a potential alternative to 3D-printed technology in craniomaxillofacial surgery. The purpose of this study was to evaluate the feasibility and accuracy of AR craniotomy guides for fronto-orbital advancement (FOA) compared to conventional 3D-printed guides.DesignRetrospective comparative study.SettingCleft and craniofacial center at a tertiary children's hospital.Patients3D-printed skull models from 9 patients with metopic or coronal craniosynostosis who underwent FOA between January 2022 and November 2023.InterventionsA novel application was developed to project AR craniotomy guides onto 3D-printed skull models. AR guides were compared to conventional 3D-printed guides by utilizing both guidance modalities. The discrepancy at 8 pre-determined reference points was measured, including bilateral nasofrontal (NF), zygomaticofrontal (ZF), barrel stave (BS), and tenon extension (TE).Main Outcomes MeasureMeasured discrepancy in millimeters between AR guides and 3D-printed guides at the pre-determined reference points.ResultsThe anterior reference points (NF, ZF) had mean discrepancies ranging from 0.31 to 0.61 mm. The posterior points had mean discrepancies ranging from 1.39 to 3.28 mm (BS, TE). There was no statistically significant difference found between the two modalities at any reference point.ConclusionsAR craniotomy guides had a high level of accuracy, particularly at the anterior reference points. AR guides demonstrated feasibility as an alternative to 3D-printed craniotomy guides, in-vitro. Further research is required to translate this novel application to cadaver models and improve precision at posterior landmarks.","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251355791"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is There Utility in Preoperative Testing of Hemoglobin Before Primary Cheiloplasty? 初级螯合整形术前检测血红蛋白是否有用？

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 Epub Date: 2024-03-15 DOI: 10.1177/10556656241239510

Aryan Shay, Megan Gaffey, Roger Roe, Alexa Robbins, Isabella Zaniletti, Adam Johnson, Larry Hartzell

{"title":"Is There Utility in Preoperative Testing of Hemoglobin Before Primary Cheiloplasty?","authors":"Aryan Shay, Megan Gaffey, Roger Roe, Alexa Robbins, Isabella Zaniletti, Adam Johnson, Larry Hartzell","doi":"10.1177/10556656241239510","DOIUrl":"10.1177/10556656241239510","url":null,"abstract":"ObjectiveTo examine whether a preoperative hemoglobin of less than 10 g/dL is associated with a higher rate of perioperative complications.DesignRetrospective review.SettingTertiary academic hospital at Arkansas Children's Hospital of Little Rock, Arkansas.PatientsA retrospective chart review evaluated patients undergoing primary cleft lip surgery from 2012 to 2017.InterventionsNo prospective intervention was performed for this study care.Main Outcome MeasuresAge, sex, medical history, weight, and perioperative complications. Hemoglobin level was collected in the preoperative area. The primary outcome was rate of perioperative complications including infection, dehiscence, return to the operating room, unplanned admission, and emergency department visit within two weeks postoperatively.Results105 patients undergoing primary cheiloplasty met inclusion criteria. Hemoglobin levels were obtained on all patients. 93.3% (n = 98) of patients had a hemoglobin of >10 g/dL before surgery, and 6.6% (n = 7) had levels <10 g/dL. 1 of 7 patients with a hemoglobin of <10 g/dL experienced a postoperative complication (Tet spell) and one patient with a hemoglobin of >10 g/dL experienced a postoperative complication (unplanned intensive care admission for respiratory distress).ConclusionsPost-operative complications are rare after primary cheiloplasty in patients with low or normal hemoglobin levels. The results of this study show that a preoperative hemoglobin of <10 g/dL does not predict perioperative complications in patients undergoing primary cheiloplasty.","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1175-1179"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140137330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Single Institution 19 Year Comparison of Furlow and Straight Line Palatoplasty Techniques in Bilateral Cleft Lip and Palate. 单个医疗机构 19 年来在双侧唇腭裂中对 Furlow 和直线腭成形术进行的比较。

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 Epub Date: 2024-03-17 DOI: 10.1177/10556656241239203

Collean Trotter, Dylan G Choi, Idean Roohani, Sarah Alfeerawi, Priyanka Naidu, Pasha Shakoori, Artur Fahradyan, Jessica A Lee, William P Magee, Mark M Urata, Jeffrey A Hammoudeh

{"title":"A Single Institution 19 Year Comparison of Furlow and Straight Line Palatoplasty Techniques in Bilateral Cleft Lip and Palate.","authors":"Collean Trotter, Dylan G Choi, Idean Roohani, Sarah Alfeerawi, Priyanka Naidu, Pasha Shakoori, Artur Fahradyan, Jessica A Lee, William P Magee, Mark M Urata, Jeffrey A Hammoudeh","doi":"10.1177/10556656241239203","DOIUrl":"10.1177/10556656241239203","url":null,"abstract":"Objective: This study aims to compare patients' speech correcting surgery and fistula rates between the Furlow and Straight Line (SLR) palatoplasty techniques when combined with greater palatine flaps for complete bilateral cleft lip and palate (BCLP) repair.Design: This was a single-center IRB approved retrospective cohort study.Setting: This study took place at an urban tertiary academic center.Patients, participants: All patients with BCLP anomalies that underwent repair between January 2003 and August 2022 were included. Patients with index operations at an outside institution or incomplete medical charting were excluded.Interventions: A total of 1552 patients underwent palatoplasty during the study period. Of these, 192 (12.4%) met inclusion criteria with a diagnosis of BCLP.Main outcome measures: Primary outcomes of this study included rate of fistula and incidence of speech correcting surgery. Secondary outcomes included rate of surgical fistula repair.Results: One hundred patients underwent SLR (52.1%) and 92 Furlow repair (47.9%). There was no significant difference in fistula rates between the SLR and Furlow repair cohorts (20.7% vs. 15.0%; p = 0.403). However, SLR was associated with lower rates of speech correcting surgery when compared to the Furlow repair (12.5% vs. 29.6%; p = 0.011).Conclusions: This study compares the effect of Furlow and SLR on speech outcomes and fistula rates in patients with BCLP. Our findings suggest that SLR resulted in an almost three times lower rate of velopharyngeal dysfunction requiring surgical intervention in patients with BCLP, while fistula rates remained similar.","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1134-1143"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Eyeing Risks: A Critical Analysis of the Use of Periorbital Steroids in Fronto-orbital Advancement. 关注风险：眶周类固醇用于前眶前移术的批判性分析。

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 Epub Date: 2024-03-28 DOI: 10.1177/10556656241241963

Daniel Y Cho, Jessica D Blum, Nicole Kurnik, Jordan W Swanson, Srinivas M Susarla, Jesse A Taylor, Richard A Hopper, Scott Bartlett, Craig B Birgfeld

{"title":"Eyeing Risks: A Critical Analysis of the Use of Periorbital Steroids in Fronto-orbital Advancement.","authors":"Daniel Y Cho, Jessica D Blum, Nicole Kurnik, Jordan W Swanson, Srinivas M Susarla, Jesse A Taylor, Richard A Hopper, Scott Bartlett, Craig B Birgfeld","doi":"10.1177/10556656241241963","DOIUrl":"10.1177/10556656241241963","url":null,"abstract":"ObjectiveTo evaluate the outcomes associated with two techniques of periorbital steroid administration in bilateral fronto-orbital advancement (FOA).DesignMulti-institutional retrospective chart reviewSettingTwo high volume, tertiary US craniofacial centersPatients, ParticipantsPatients who underwent FOA between 2012 and 2021InterventionsPatients were divided into three cohorts based on method of steroid administration. Groups GEL and INJ represent those who received steroids in the form of triamcinolone soaked gelfoam or direct injection of dilute triamcinolone to the frontal/periorbital region, respectively. Group NON did not receive any periorbital steroids.Main Outcome Measure(s)Peri-operative outcomes including hospital length of stay and complications were evaluated based on method of periorbital steroid administration. Variables predictive of infectious complications were assessed using stepwise logistic regression.ResultsFour hundred and twelve patients were included in our sample (INJ:249, GEL:87, NON:76). Patients in the INJ group had a higher ASA class (P < .001) while patients in the NON group were significantly more likely to be syndromic (P < .001) and have multisuture craniosynostosis (P < .001). Rate of infectious complications for each cohort were NON: 2.6%, INJ: 4.4%, and GEL: 10.3%. There was no significant difference between groups in hospital length of stay (P = .654) or rate of post-operative infectious complications (P = .061). Increased ASA class (P = .021), increased length of stay (P = .016), and increased intraoperative narcotics (P = .011) were independent predictors of infectious complications.ConclusionsWe identified a dose-dependent relationship between periorbital steroids and rate of postoperative infections, with key contributions from ASA class, hospital length of stay, and dose of intraoperative narcotics.","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1210-1218"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elastic Chain Premaxillary Retraction Appliance Does Not Increase Inter-Canthal Dimension in Patients with Bilateral Cleft Lip and Palate. 弹性链式下颌前缩矫正器不会增加双侧唇腭裂患者的颌骨间尺寸。

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 Epub Date: 2024-03-21 DOI: 10.1177/10556656241241200

Hamad Burashed, Cory M Resnick, Elizabeth E Ross, John B Mulliken, Bonnie L Padwa

{"title":"Elastic Chain Premaxillary Retraction Appliance Does Not Increase Inter-Canthal Dimension in Patients with Bilateral Cleft Lip and Palate.","authors":"Hamad Burashed, Cory M Resnick, Elizabeth E Ross, John B Mulliken, Bonnie L Padwa","doi":"10.1177/10556656241241200","DOIUrl":"10.1177/10556656241241200","url":null,"abstract":"ObjectiveTo determine if the elastic chain premaxillary retraction (ECPR) appliance increases inter-medial and inter-lateral canthal dimension in patients with bilateral complete cleft lip and palate (BCLP).DesignRetrospective cohort study.SettingSpecialized tertiary care facility.Patients, Participants126 patients with BCLP; 75 had ECPR, 51 had no pre-surgical manipulation.InterventionsThree-dimensional facial photographs were obtained prior to insertion of appliance (T0), post-appliance therapy prior to appliance removal/labial repair (T1), and several months after labial repair (T2) for a longitudinal ECPR group, and were obtained after age 4 years (T3) for a non-longitudinal ECPR group and for the non-ECPR group.Main Outcome MeasuresInter-medial and inter-lateral canthal dimension (en-en, ex-ex) was determined for all groups/time-points. Measurements were compared between groups and to norms.ResultsThe mean en-en and ex-ex was 32.6 ± 3.2 mm and 84.4 ± 6.3 mm for the ECPR group and 33.5 ± 3.1 mm and 86.7 ± 7.2 mm for the non-ECPR group at T3. Inter-medial and inter-lateral canthal dimensions were significantly greater than normal (P < .05) in both groups; there was no significant difference between groups (P > .05). The mean en-en and ex-ex for the Longitudinal ECPR group was 27.5 ± 2.4 mm and 66.7 ± 3.7 mm at T0, 29.6 ± 2.4 mm and 70.4 ± 2.9 mm at T1, and 29.2 ± 2.3 mm and 72.3 ± 3.8 mm at T2. en-en and ex-ex increased significantly from T0-T1 (P < .05), decreased at T2 (P > .05) and was significantly larger than normal at all time-points (P < .05).ConclusionsInter-medial and inter-lateral canthal dimension increased after ECPR but returned to baseline growth trajectory. These dimensions were above normal at all time-points. There was no difference between those that did and did not have dentofacial orthopedic manipulation.","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1195-1200"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140186104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barriers in Cleft Service Access in Sub-Saharan Africa: A Thematic Analysis of Practical Needs of Rural Families. 撒哈拉以南非洲地区在获得裂隙服务方面存在的障碍：农村家庭实际需求专题分析》。

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 Epub Date: 2024-04-01 DOI: 10.1177/10556656241244976

Abdurrazaq Olanrewaju Taiwo, Uta Lehmann, Vera Scott, Isah Shafi'u, Suleman Gusau Lawal, Usamatu Abdulmajid, Ramat Oyebummi Braimah, Adebayo Aremu Ibikunle, Abdullahi Bello Abubakar, Bala Mujtaba, Mike Eghosa Ogbeide, Suwaiba Labbo-Jadadi, Olufemi Ibrahim Adigun, Bruno Oludare Ile-Ogedengbe

{"title":"Barriers in Cleft Service Access in Sub-Saharan Africa: A Thematic Analysis of Practical Needs of Rural Families.","authors":"Abdurrazaq Olanrewaju Taiwo, Uta Lehmann, Vera Scott, Isah Shafi'u, Suleman Gusau Lawal, Usamatu Abdulmajid, Ramat Oyebummi Braimah, Adebayo Aremu Ibikunle, Abdullahi Bello Abubakar, Bala Mujtaba, Mike Eghosa Ogbeide, Suwaiba Labbo-Jadadi, Olufemi Ibrahim Adigun, Bruno Oludare Ile-Ogedengbe","doi":"10.1177/10556656241244976","DOIUrl":"10.1177/10556656241244976","url":null,"abstract":"ObjectiveTo explore the experiences and perceptions of barriers of parents and family members of patients with cleft lip and palate in accessing cleft services in remote northwest Nigeria.DesignFace-to-face semi-structured audio recorded interviews were used to obtained qualitative textual data. Thematic analysis using interpretative descriptive techniques was employed to understand the participants' lived experiences with barriers and accessibility to cleft services.SettingParticipants were from Sokoto, Kebbi and Zamfara states in remote northwest, Nigeria.ParticipantsConsisted of 22 caregivers (17 parents and 5 extended family members) were purposively sampled between 2017 and 2020Main outcome measuresBarriers experienced while accessing cleft services were identified during thematic analysis.ResultOver three quarter of the respondents had patients with both cleft lip and palate and without any previous family history (n = 20). About two-thirds of the participants (n = 15) were females. Most of the interviews were conducted before the surgeries (n = 15).Five themes emergedlack of information, financial difficulty, misrepresentation from health workers, multiple transportation and previous disappointment.ConclusionsAreas of poor awareness, misinformation from primary health care workers, financial hurdles, multiple transportation logistics and others were identified. Aggressive broadcasting of information through radio, timely treatment and collaboration with influential religious leaders were emphasized. Support, grants and subsidies from government and voluntary agencies are encouraged to mitigate the huge out of pocket cost of cleft care in the region.","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1219-1227"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140337438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of a Novel TP63 Variant in a Chinese Patient with Orofacial Clefts and Ectrodactyly: Case Report and Literature Review. 在一名患有口面裂和外耳道畸形的中国患者中发现新型 TP63 变体：病例报告与文献综述

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 Epub Date: 2024-05-08 DOI: 10.1177/10556656241241132

Leheng Jiang, Chanyuan Jiang, Tao Song, Yongqian Wang, Nuo Si, Haidong Li, Ningbei Yin

引用次数: 0

IFT122 Regulates Proliferation of mEPMCs Through the Shh Signaling Pathway by Primary Cilia. IFT122通过原纤毛Shh信号通路调控mEPMCs增殖

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 DOI: 10.1177/10556656251352294

Ruoyu Mei, Jianan Guo, Jie Yin, Wei He, Fang Wang

{"title":"IFT122 Regulates Proliferation of mEPMCs Through the Shh Signaling Pathway by Primary Cilia.","authors":"Ruoyu Mei, Jianan Guo, Jie Yin, Wei He, Fang Wang","doi":"10.1177/10556656251352294","DOIUrl":"https://doi.org/10.1177/10556656251352294","url":null,"abstract":"ObjectiveTo investigate how intraflagellar transport protein 122 (IFT122) regulates murine embryonic palate mesenchymal cell (mEPMC) proliferation via the Sonic Hedgehog (Shh) pathway and its dependency on primary cilia integrity, elucidating mechanisms underlying cleft palate pathogenesis.DesignIntraflagellar transport protein 122 was silenced in E14.5-derived mEPMCs using lentiviral shRNA. Primary cilia morphology (immunofluorescence), Shh signaling components (Smo, Gli3 via qPCR/Western blot), and proliferation markers (CCK-8 assay, Proliferating Cell Nuclear Antigen [PCNA], Cyclin D1) were analyzed. Rescue experiments employed the Smoothened agonist (SAG) to activate Shh signaling.Main Outcome MeasureCilia incidence and length; Smo/Gli3 mRNA and protein expression; Gli3A/Gli3R ratio; cell proliferation rates (OD values, PCNA, Cyclin D1); SAG-mediated rescue effects.ResultsIntraflagellar transport protein 122 knockdown reduced cilia incidence (10.2% vs 2.4%, P < .01) and length (7.8 μm vs 3.4 μm, P < .01), impaired Smo trafficking (mRNA↓42%, protein↓50%), suppressed Gli3A/Gli3R ratio (↓62%), and inhibited proliferation (PCNA/Cyclin D1↓40%-60%, P < .01). Smoothened agonist partially restored Smo expression (↑1.8×), Gli3 activation, and proliferation (P < .05), confirming cilia-dependent Shh regulation.ConclusionIntraflagellar transport protein 122 maintains primary cilia structure to enable Shh-driven mEPMC proliferation. Its deficiency disrupts cilia integrity and Shh signaling, linking ciliary dysfunction to cleft palate. Partial rescue by SAG validates the mechanism, highlighting therapeutic potential for targeting cilia-Shh axis defects.","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251352294"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144545784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patient-Reported Outcomes of Primary Cleft Rhinoplasty: A Long-Term Assessment Using CLEFT-Q. 初次鼻裂成形术患者报告的结果：使用Cleft - q进行长期评估。

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 DOI: 10.1177/10556656251355040

Isabel A Ryan, Jinggang J Ng, Jusung Kim, Philip D Tolley, Oksana A Jackson, David W Low, Scott P Bartlett, Jesse A Taylor, Eric C Liao, Jordan W Swanson

{"title":"Patient-Reported Outcomes of Primary Cleft Rhinoplasty: A Long-Term Assessment Using CLEFT-Q.","authors":"Isabel A Ryan, Jinggang J Ng, Jusung Kim, Philip D Tolley, Oksana A Jackson, David W Low, Scott P Bartlett, Jesse A Taylor, Eric C Liao, Jordan W Swanson","doi":"10.1177/10556656251355040","DOIUrl":"https://doi.org/10.1177/10556656251355040","url":null,"abstract":"ObjectiveRhinoplasty maneuvers at the time of cleft lip (CL) repair remain controversial. Particularly, the impact of primary rhinoplasty (PR) on patient-reported outcomes (PROs) and quality of life (QoL) is largely unknown. This study aims to compare PROs and QoL in patients with CL who did or did not undergo PR.DesignRetrospective study.SettingAcademic tertiary care center.Patients, ParticipantsPatients with CL who completed the CLEFT-Q from 2021 to 2024 and had undergone definitive CL repair at our institution.InterventionsPR or no primary rhinoplasty (NPR) at the time of CL repair.Main Outcome Measure(s)The primary outcome was CLEFT-Q scores across facial appearance, health-related QoL, and facial function domains.ResultsA total of 109 patients with 110 CLEFT-Q responses were included. 22% (n = 24) underwent NPR and 78% (n = 85) PR at time of CL repair. Median age at lip repair was 4.6 [1.6] months, and at CLEFT-Q survey was 10.2 [1.6] years. Among those with intermediate rhinoplasty, nose scores were significantly higher in PR compared to NPR on overall (75 vs. 57, P = .026) and unilateral CL analysis (75 vs. 57, P = .018). NPR patients were significantly more likely to undergo intermediate rhinoplasty than PR patients (71%, n = 17 vs 33%, n = 28, P < .001).ConclusionsPR is associated with improved self-perception of nasal appearance in school-aged children with CL compared to those who did not undergo PR.","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251355040"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feeding Management and Palate Repair Timing in Infants with Cleft Palate with and without Pierre Robin Sequence: A Multisite Study. 有皮埃尔-罗宾序列和无皮埃尔-罗宾序列腭裂婴儿的喂养管理和腭修复时机：多站点研究。

IF 1.1 4区医学

Cleft Palate-Craniofacial Journal Pub Date : 2025-07-01 Epub Date: 2024-03-15 DOI: 10.1177/10556656241239766

Jessica L Williams, Kari M Lien, Richard Kirschner, Gregory Allen, Kathy Chapman

{"title":"Feeding Management and Palate Repair Timing in Infants with Cleft Palate with and without Pierre Robin Sequence: A Multisite Study.","authors":"Jessica L Williams, Kari M Lien, Richard Kirschner, Gregory Allen, Kathy Chapman","doi":"10.1177/10556656241239766","DOIUrl":"10.1177/10556656241239766","url":null,"abstract":"ObjectivesCompare the feeding management practices in infants with cleft palate with and without Pierre Robin sequence (PRS) and determine if specific feeding difficulties or interventions predict delayed palate repair.DesignRetrospective cross-sectional study.SettingSeventeen cleft palate teams contributed data.Patients414 infants were included in this study: 268 infants with cleft palate only and 146 infants with cleft palate and PRS.ProceduresData were collected via parent interview and electronic health records.Main Outcome MeasuresOutcomes for the primary objective included categorical data for: history of poor growth, feeding therapy, milk fortification, use of enteral feeding, and feeding difficulties. The outcome for the secondary objective was age in months at primary palate repair.ResultsInfants with PRS had a significantly higher prevalence of feeding difficulties (81% versus 61%) and poor growth (29% versus 15%) compared to infants with cleft palate only. Infants with PRS received all feeding interventions-including feeding therapy, milk fortification, and enteral feeding-at a significantly higher frequency. Infants with PRS underwent primary palate repair at a mean age of 13.55 months (SD = 3.29) which was significantly (P < .00001) later than infants with cleft palate only who underwent palate repair at a mean age of 12.05 months (SD = 2.36). Predictors of delayed palate repair included diagnosis of PRS as well as Hispanic ethnicity and a history of poor growth.ConclusionsThese findings can be used to establish clinical directives focused on providing early, multimodal feeding interventions to promote optimal growth and timely palate repair for infants with PRS.","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1180-1189"},"PeriodicalIF":1.1,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11401965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140137329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0