Cleft Palate-Craniofacial Journal最新文献

{"title":"Parental Experiences on Learning About and Caring for Children with Cleft Lip and Palate: A Qualitative Study from South India.","authors":"Shuba Kumar, Rani Mohanraj, Thailavathy Vaidhyalingam, Subhiksha Chakkaravarthi, Badri Thiruvenkatachari","doi":"10.1177/10556656241298217","DOIUrl":"https://doi.org/10.1177/10556656241298217","url":null,"abstract":"<p><strong>Objectives: </strong>The study aimed to understand parents' reactions to cleft, the manner in which they learned about its presence, and the challenges they faced in caring for their child with a view to providing healthcare professionals insights toward enhancing care delivery.</p><p><strong>Design: </strong>Qualitative in-depth interviews using the grounded theory approach were carried out with 11 mothers and fathers of children with cleft lip and palate (CLP) attending a cleft speciality hospital in Chennai city, in South India.</p><p><strong>Results: </strong>Analysis resulted in the discovery of 5 core categories, learning about CLP-when and how, reactions and attributions to CLP, learning about and expectations from treatment, caring for a child with CLP and support systems. Feelings of shock and bewilderment when they learned of the presence of cleft in their child was reported by most parents. Poor awareness of cleft, difficulties in feeding, and concerns for the child's future were major sources of disquiet. The presence of support from family and friends and interactions with other parents of children with cleft helped them to cope better.</p><p><strong>Conclusions: </strong>The results highlight the need for enhancing understanding of cleft among parents and strengthening them emotionally, thereby empowering them to provide effective care for their child. There is an urgent need to develop standardized information materials for parents to ensure that they have clear, consistent, and reliable information on the care of their child.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241298217"},"PeriodicalIF":1.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardization of Videorecorded Speech Samples for Children with Cleft Palate: Methods to Facilitate High-Quality Speech Outcomes Data Collection.","authors":"Adriane L Baylis, Caitlin E Cummings, Kari M Lien, Thomas J Sitzman, Richard E Kirschner, Kathy L Chapman","doi":"10.1177/10556656231217645","DOIUrl":"10.1177/10556656231217645","url":null,"abstract":"<p><strong>Background: </strong>Collection of high-quality videorecorded speech samples is essential for speech outcomes research.</p><p><strong>Solution: </strong>Cleft palate team SLPs were trained to collect standard videorecorded speech samples in the clinic setting across 20 sites in North America. Standard training and equipment was provided.</p><p><strong>What we did that is new: </strong>Quality management procedures were developed and utilized to verify video quality and protocol adherence. Over 97% of speech samples collected by trained SLPs met defined quality standards.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"2090-2096"},"PeriodicalIF":1.1,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11130073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138446720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Influencing Nasoalveolar Molding Treatment Completion and Noncompletion in Infants with Cleft Lip and Palate.","authors":"Elisa I Herrman, Ross A Dierkhising, Sarah K Lee, Thomas J Salinas, Elise W Sarvas, Christopher F Viozzi, Olivia M Muller","doi":"10.1177/10556656241293682","DOIUrl":"https://doi.org/10.1177/10556656241293682","url":null,"abstract":"<p><strong>Objective: </strong>Identify sociodemographic factors and comorbidities predictive of nasoalveolar molding (NAM) treatment completion and noncompletion in infants with cleft lip with or without (+/-) cleft palate in a rural-suburban population.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Tertiary medical center.</p><p><strong>Patients, participants: </strong>Infants diagnosed with cleft lip +/- cleft palate who initiated NAM treatment between 2013 and 2023. Forty-seven patients met inclusion criteria.</p><p><strong>Main outcome measure(s): </strong>Prevalence of NAM treatment completion, defined as continued attendance of NAM appointments until initial lip repair surgery.</p><p><strong>Results: </strong>NAM treatment noncompletion rate of 23.4%. Noncomplete NAM treatment was associated with greater additional unscheduled NAM visits (<i>P</i> < .001); increased days inpatient after birth (<i>P</i> < .001); NICU admission (<i>P</i> < .001); public insurance (<i>P</i> = .007); preterm birth (<i>P</i> = .008); history of social work visits (<i>P</i> = .024); increased comorbidities (<i>P</i> = .028); non-Caucasian race (<i>P</i> = .034); and presence of siblings (<i>P</i> = .036). Associated comorbidities included use of feeding tube (<i>P</i> < .001); and conditions related with renal (<i>P</i> < .001); cardiac (<i>P</i> = .004); failure to thrive (<i>P</i> = .009); syndromes (<i>P</i> = .009); orthopedic (<i>P</i> = .011); pulmonary (<i>P</i> = .022); and ophthalmologic systems (<i>P</i> = .041).</p><p><strong>Conclusions: </strong>Increased overall health complexity, public insurance status, and need for social work support were identified as factors associated with NAM noncompletion. These variables can help identify patients at risk of noncompletion and empower providers to supply individualized support and resources.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241293682"},"PeriodicalIF":1.1,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alveolar Bone Graft Supplemented With Stromal Vascular Fraction in Patients With Permanent Dentition: A Randomized Study.","authors":"Kleber Tetsuo Kurimori, Endrigo Oliveira Bastos, Paulo Roberto Pelucio Camara, Beatriz Mascarenhas Dias, Giovanna Layse Uyeda, Nivaldo Alonso","doi":"10.1177/10556656241296711","DOIUrl":"https://doi.org/10.1177/10556656241296711","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate bone development in patients with alveolar clefts and permanent dentition treated with alveolar bone graft supplemented with stromal vascular fraction (SVF).</p><p><strong>Design: </strong>Clinical, prospective, randomized.</p><p><strong>Location: </strong>Single tertiary care institution.</p><p><strong>Patients: </strong>Eighteen participants with unilateral alveolar cleft and permanent dentition were included. Patients with other comorbidities were excluded.</p><p><strong>Intervention: </strong>The control group underwent alveolar bone grafting (ABG) using iliac crest bone, while the experimental group underwent the same treatment, supplemented with SVF. Adipose tissue was collected by abdominal liposuction, and the SVF was processed using mechanical methods (decantation, microfragmentation, and filtration).</p><p><strong>Main outcome measurement: </strong>Bone formation and bone graft integration rate in alveolar cleft at 6 months postsurgery using 3-dimensional tomographic methods and density measurements.</p><p><strong>Results: </strong>The amount of bone graft correlated with an improvement in the relationship between the cleft and noncleft sides (R = 0.78, <i>P</i> < .001) and an improvement in alveolar cleft density (R = 0.69, <i>P</i> = .005), but did not correlate with the graft integration rate. The experimental group showed larger cleft sizes (0.83 × 1.74 cm³, <i>P</i> = .021) and older patients (17.35 × 27.6 years, <i>P</i> = .002), and did not differ in terms of bone development variables when compared to the control group.</p><p><strong>Conclusion: </strong>ABG supplemented with SVF showed statistically similar bone development results, but with a better trend than conventional ABG. Additionally, the studied groups had asymmetric pre-existing characteristics, with greater severity in the experimental group. A larger study will be necessary to mitigate preoperative characteristic differences and to more accurately compare the results between the methods.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241296711"},"PeriodicalIF":1.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphometric Evaluation of the Greater Palatine Foramen in Patients With Cleft lip and Palate (CLP) and Controls: A CBCT Study.","authors":"Salma Tabatabaei, Maryam Paknahad, Sajjad Adab","doi":"10.1177/10556656241300901","DOIUrl":"https://doi.org/10.1177/10556656241300901","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to use cone beam computed tomography (CBCT) scans to compare the morphometric characteristics of the greater palatine foramen (GPF) in unilateral and bilateral cleft lip/palate patients (CL/P) and non-cleft (NC) individuals.</p><p><strong>Method and material: </strong>One hundred patients with CL/P (78 unilateral and 22 bilateral) and 100 non-cleft individuals had their GPF morphometrically assessed in CBCT images. The antero-posterior width and medio-lateral width of the GPF, the distance between the right and left GPFs, the mesio-distal location of the GPF with respect to the molar teeth, the distance between the GPF and the hamulus of the medial pterygoid plate, and the distance between the GPF and the palatine alveolar ridge were measured on these images. The Kruskal-Wallis and Chi-square tests were employed to ascertain if there were any notable disparities across the 3 groups.</p><p><strong>Results: </strong>The GPF's antero-posterior width and medio-lateral width, and distance from the hamulus and palatine alveolar ridge were considerably smaller in the unilateral cleft lip/palate (UCL/P) and bilateral cleft lip/palate (BCL/P) patients than in the NC individuals. However, no significant difference was observed between the BCL/P and UCL/P groups in terms of these parameters. The distance between GPFs and the location of the GPF did not exhibit any significant differences among the 3 groups.</p><p><strong>Conclusion: </strong>Certain morphometric parameters of the GPF were significantly different in CL/P patients. Understanding the anatomy of this area is crucial for successful treatment of individuals with CL/P with minimal complications.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241300901"},"PeriodicalIF":1.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Posterior Superior Alveolar Canal in Individuals With Cleft Lip and Palate Using Cone Beam Computed Tomography.","authors":"Tannishtha Tannishtha, G Subhas Babu, Vikram Shetty, Vidya Ajila","doi":"10.1177/10556656241298103","DOIUrl":"https://doi.org/10.1177/10556656241298103","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the posterior superior alveolar canal (PSAC) in individuals with cleft lip and palate (CLP) by comparing them with individuals with no cleft lip and palate (NC) using cone beam computed tomography (CBCT).</p><p><strong>Setting: </strong>This is a cross-sectional, analytical study with a prospective sample.</p><p><strong>Patients, participants: </strong>CBCT scans of 29 individuals with no cleft and palate (Group I) and 29 individuals with cleft lip and palate (Group II) were used.</p><p><strong>Interventions: </strong>PSAC was evaluated and compared for its position, diameter, and distance between the individuals with CLP and NC using CBCT scans.</p><p><strong>Results: </strong>The mean age of individuals in Group I and II were 12.93 and 11.82 years, respectively. The distribution of individuals based on gender comprised of 51.7% males and 48.3% females in both the study groups. PSAC was present in both right and left maxillary sinus in 100% of the study subjects of Group I and Group II. The most prevalent position of PSAC in Group I and Group II was on the lower third and middle third of lateral wall of maxillary sinus, respectively. The mean diameter was higher in Group II (1.2962 mm) when compared to Group I (1.0897 mm) which showed statistically significant value (<i>P</i> = .008).</p><p><strong>Conclusion: </strong>The promising results obtained from the present study demonstrates the importance of knowing the precise anatomical location of the PSAC in individuals with cleft lip and palate by using CBCT which is reliable, less time consuming and cost effective imaging tool.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241298103"},"PeriodicalIF":1.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization of a Perioperative Care Pathway for Pediatric Alveolar Bone Grafting: A Quality Improvement Initiative.","authors":"Thomas R Cawthorn, Altay Baykan, Rebecca L Hartley, Miller Smith, Kevin Robertson, Nina Hardcastle, Adam O Spencer, Frankie O G Fraulin, A Robertson Harrop","doi":"10.1177/10556656241301954","DOIUrl":"https://doi.org/10.1177/10556656241301954","url":null,"abstract":"<p><strong>Objective: </strong>To develop, implement, and evaluate a standardized perioperative care pathway for pediatric patients undergoing alveolar bone grafting from the anterior iliac crest.</p><p><strong>Design: </strong>A historical control group of 40 patients was reviewed retrospectively and compared to a prospectively collected treatment group of 40 patients who were treated with the new pathway.</p><p><strong>Setting: </strong>Tertiary-level academic pediatric hospital between 2018 and 2021.</p><p><strong>Patients: </strong>Pediatric patients with nonsyndromic cleft lip and palate undergoing alveolar bone grafting.</p><p><strong>Intervention: </strong>A perioperative clinical care pathway was specifically designed for patients undergoing alveolar bone grafting from the anterior iliac crest. The pathway involved standardization of perioperative care, ultrasound-guided regional anesthesia for both surgical sites, and scheduled postoperative analgesia.</p><p><strong>Main outcome measures: </strong>(1) Length of hospital stay; (2) opioid consumption postoperatively; and (3) volume of oral intake in the first 24 h postoperatively. Data was analyzed via comparison of means (Student's t-test for continuous data and Chi-square test for categorical data) and control chart analysis.</p><p><strong>Results: </strong>Compared to the control group, patients in the treatment group had lower mean length of stay (26.8 vs 37.8 h, <i>p </i>< .001), lower mean morphine consumption postoperatively (8 vs 34 mcg/kg, <i>p </i>= .008), and a higher proportion of patients not requiring any postoperative opioid use (80% vs 50%, <i>p </i>= .005).</p><p><strong>Conclusions: </strong>Implementation of a standardized clinical care pathway for pediatric patients undergoing alveolar bone grafting from the anterior iliac crest is feasible and was associated with significant reductions in postoperative length of stay and postoperative opioid requirements.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241301954"},"PeriodicalIF":1.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional Units Analysis of Mandibular Morphology in Patients With Parry-Romberg Syndrome.","authors":"Xiyuan Li, Zhiyong Zhang","doi":"10.1177/10556656241300802","DOIUrl":"https://doi.org/10.1177/10556656241300802","url":null,"abstract":"<p><strong>Objective: </strong>To characterize mandibular morphology in patients with Parry-Romberg syndrome (PRS).</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Setting: </strong>A craniofacial center.</p><p><strong>Patients: </strong>Thirty-three patients with PRS affecting mandible.</p><p><strong>Interventions: </strong>Preoperative computed tomography data were analyzed using Mimics 26.0 (Materialise Inc.). Distances between landmarks-condyle process (Con), coronoid process (Cor), mandibular foramen (IAF), gonion (Go), and mental foramen-were measured to represent the sizes of skeletal units. Positional asymmetry was reflected by angles between lines connecting bilateral landmarks and the occlusal plane.</p><p><strong>Main outcome measure(s): </strong>Bilateral differences in unit sizes were compared. Absolute difference (Δ) > 5 mm and relative size (RS) < 80% were set to evaluate the severity of hypoplasia. Angular measurements were compared to 0° using one-sample <i>t</i> tests. Pearson correlation analysis was conducted to examine the relationship between onset ages and both RS and angular measurements.</p><p><strong>Results: </strong>The affected side's skeletal units were smaller. Severe hypoplasia was more common in the angular unit. Angles between Con-Con', Cor-Cor', IAF-IAF', and the occlusal plane were less than 0°, whereas the angle with Go-Go' was greater than 0°. Age of onset was positively correlated with the condylar unit size and the Con-Con' to occlusal plane angle.</p><p><strong>Conclusions: </strong>Patients with PRS affecting mandible exhibit smaller skeletal units on the affected side, particularly in the angular unit. Most landmarks on affected side tend to cluster toward the occlusal plane. Earlier onset of PRS correlates with more pronounced condylar asymmetry. Evaluating the severity of functional units involvement and implementing appropriate treatment should be considered.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241300802"},"PeriodicalIF":1.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Single Stage Management of a Severe Form of Grade 3 Hypertelorism With Sincipital and Basal Encephaloceles-Lessons Learnt!","authors":"Anil Murarka, Arun Sharma, Anurag Sharma, Sachin Gupta, Gaurav Kakkar, Ketan Kulkarni, Maninder Dhaliwal, Veena Raghunathan, Mohit Sharma","doi":"10.1177/10556656241299201","DOIUrl":"https://doi.org/10.1177/10556656241299201","url":null,"abstract":"<p><p>The article elucidates the management of a case of severe form of grade III hypertelorism with an intercanthal distance of 61 mm in a 4-year-old child. The management was especially challenging because of the patient's young age, degree of hypertelorism, wide cleft and simultaneous presence of 2 big (sincipital & basal) encephaloceles and a lipoma in the midline. This paper attempts to describe the attempted surgery, postoperative course and the learnings derived from its management to probably create a road-map for surgeons faced with such a challenge in future.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241299201"},"PeriodicalIF":1.1,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142711601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an Artificial Intelligence-Based Algorithm for the Assessment of Skeletal Age and Detection of Cervical Vertebral Anomalies in Patients with Cleft Lip and Palate.","authors":"Gaithoiliu Kamei, Puneet Batra, Ashish Kumar Singh, Garima Arora, Simran Kaushik","doi":"10.1177/10556656241299890","DOIUrl":"https://doi.org/10.1177/10556656241299890","url":null,"abstract":"<p><p>To develop an artificial intelligence (AI)-based algorithm for the assessment and comparison of skeletal maturation in patients with and without cleft lip and/or palate and to detect the presence of cervical vertebral anomalies (CVAs).</p><p><p>Retrospective cohort study.</p><p><p>A university orthodontic clinic and comprehensive cleft care centers.</p><p><p>In total, 1080 cephalograms of patients with and without unilateral cleft lip and palate (UCLP) aged 6 to 18 years, without any associated syndromes, congenital disorders, or history of trauma or illness, were collected. About 960 cephalograms were assessed in the study upon elimination of poor-quality lateral cephalograms.</p><p><p>The MobileNet architecture using TensorFlow framework was employed to develop 2 convolutional neural network (CNN)-based AI models for automated assessment of skeletal age and detection of CVAs. Inter-rater reliability for manual cervical vertebral maturation (CVM) staging was assessed using Cohen's kappa coefficient, and intraclass correlation coefficient (ICC) was calculated. The results of each model were separately analyzed using chi-square test, and the statistical significance was tested at 5% level.</p><p><p>The CNN-based AI model yielded an average accuracy rate of 74.5%, with an accuracy of up to 88% for detecting skeletal maturity and an accuracy rate of 83% for detecting CVAs.</p><p><p>It can be concluded that CVM methods help detect skeletal maturity objectively in patients with UCLP and have shown delayed skeletal growth compared to patients without UCLP. CVAs were found to be more prevalent in patients with UCLP than in their non-cleft counterparts, with these findings facilitated by utilizing a novel AI algorithm.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241299890"},"PeriodicalIF":1.1,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}