Sahejbir S Bhatia, Paul W Hung, Alexander E Velazquez, Kayla Prezelski, Lucas M Harrison, Timothy Booth, Rami R Hallac, Alex A Kane, Paymon Sanati-Mehrizy
{"title":"Evaluating 3D Morphometrics for Assessing Micrognathia in Neonates with Severe Pierre Robin Sequence: A Case-Control Study.","authors":"Sahejbir S Bhatia, Paul W Hung, Alexander E Velazquez, Kayla Prezelski, Lucas M Harrison, Timothy Booth, Rami R Hallac, Alex A Kane, Paymon Sanati-Mehrizy","doi":"10.1177/10556656261431485","DOIUrl":"10.1177/10556656261431485","url":null,"abstract":"<p><p>ObjectiveTo compare 3D mandibular morphometrics of neonates with Pierre Robin sequence (PRS) to age-matched controls, establish normative data, and better understand anatomic differences.DesignRetrospective case-control study.SettingTertiary pediatric medical center.PatientsTwenty-five neonates with non-syndromic PRS (mean age 15 days) with computed tomography (CT) scans of the head and mandibular distraction osteogenesis (MDO) and 25 age-matched controls (mean age 14 days) with CT scans of the head.InterventionsNone.Main Outcome MeasuresStandardized morphometric measurements, including linear distances, angles, and ratios, were generated from digital 3D reconstructions of mandibular anatomy.ResultsAsymmetry in PRS body length was significantly higher than in control mandibles (<i>p</i> = .006). PRS measurements larger than control measurements included intercondylar distance (<i>p</i> = .044), intergonial distance (<i>p</i> = .008), pogonion-interdental distance (<i>p</i> = .015), ramus height (<i>p</i> = .001), and ramus height to body length ratio (<i>p</i> < .001). PRS measurements smaller than control measurements included intercondylar angle (<i>p</i> < .001), body length (<i>p</i> < .001), and effective mandibular length (<i>p</i> < .001).ConclusionsIn a cohort of neonates with PRS severe enough to warrant MDO, findings indicate that micrognathia is constituted by a wide and antero-posteriorly short mandible for its height. Except for body length, PRS and control mandibles are similarly asymmetrical in other dimensions. These findings may contextualize structural abnormalities contributing to glossoptosis and airway obstruction in PRS, with implications for surgical management, although decision-making remains primarily guided by clinical severity of airway obstruction.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3845-3851"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13646437/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Skeletal Facial Patterns in Cleft Lip and/or Palate: A Cross-Sectional Study in a Brazilian Craniofacial Center.","authors":"Flavine Seltenreich, Thais Verdi, Juliane Carla Taufer, Geisiane Garcia Moreira, Lilian Rigo","doi":"10.1177/10556656261423054","DOIUrl":"10.1177/10556656261423054","url":null,"abstract":"<p><p>ObjectiveTo describe the demographic and clinical profile of individuals with cleft lip and/or palate (CL/P) and to analyze the association between cleft type, skeletal facial pattern, gender, and ethnicity.DesignCross-sectional study.SettingDental Clinic of the Craniofacial Deformities Rehabilitation Center of Southern Brazil.PatientsFour hundred orthodontic records of patients with CL/P treated, between 2018 and 2020.Main Outcome MeasureThe variables analyzed were cleft type, gender, race/color, skeletal facial pattern, facial profile, and maxillary and mandibular positioning. Data were evaluated using frequencies and multinomial logistic regression (crude and adjusted analysis), estimating odds ratios (OR) and respective 95% confidence intervals (CI). Variables with <i>P</i> < .10 in the crude analysis were included in the adjusted model, and those with <i>P</i> < .05 remained in the adjusted modelResultsThe mean age was 13 years (SD ± 9.5), 64% were male, and 79.3% were white. The most prevalent cleft was unilateral transforaminal (36%). Type II facial pattern predominated (45%), with a convex profile (64%) and retrusion of the maxilla (53%) and mandible (73%). A significant association was observed between male gender and post-foraminal clefts (OR = 2.67; 95% CI 1.44-4.95) and between skeletal type III facial pattern and post-foraminal (OR = 2.90; 95% CI 1.14-7.36) and transforaminal (OR = 3.45; 95% CI 1.53-7.79) clefts.ConclusionsA high prevalence of convex facial profile, skeletal type II pattern, and maxillomandibular retrusion was observed. Male sex was associated with higher odds of post-foraminal cleft, and skeletal type III facial was associated with higher odds of post-foraminal and transforaminal clefts.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3662-3668"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cody Tyson, Luke Anderson, Rahim Hirani, Rene Myers, John Grant
{"title":"The Use of Infrared Thermal Imaging for Real-Time Flap Perfusion in Revision Palatoplasty with Buccinator Myomucosal Flaps.","authors":"Cody Tyson, Luke Anderson, Rahim Hirani, Rene Myers, John Grant","doi":"10.1177/10556656261422884","DOIUrl":"10.1177/10556656261422884","url":null,"abstract":"<p><p>BackgroundInfrared thermal imaging (IRTI) provides real-time visualization of tissue perfusion and may improve outcomes in flap-based reconstructive procedures. This study evaluated the impact of IRTI on complication rates following revision palatoplasty using a buccinator myomucosal flap (BMMF).MethodsA retrospective cohort study was performed on patients who underwent revision palatoplasty with BMMF between 2021 and 2024 at a single institution. Postoperative outcomes, including partial flap loss, dehiscence, and fistula formation, were compared between cases in which IRTI was utilized and those evaluated solely by traditional clinical assessment. A brief expected-cost analysis was performed.ResultsAmong 80 cases, 20 (25%) utilized IRTI for intraoperative flap evaluation and 60 (75%) did not. The overall complication rate was significantly lower in the IRTI group compared to the non-IRTI group (10% vs. 35%; <i>p = .</i>032). Partial flap loss occurred in 5.0% of IRTI cases versus 18.3% of non-IRTI cases (<i>p = .</i>139). No major complications occurred in the IRTI cohort, whereas 33.3% (7/21) of complications in the non-IRTI group required operative intervention. With conservative estimates for revision surgery, this corresponded to approximately $10,640 in savings per patient.ConclusionIntraoperative use of IRTI during revision palatoplasty with BMMF was associated with significantly lower complication rates and reduced severity of complications. By providing real-time, objective information about flap perfusion, IRTI may enhance intraoperative decision-making, improve flap viability, and reduce postoperative morbidity. These findings support IRTI as a cost-effective and noninvasive adjunct to standard clinical assessment in reconstructive surgery.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3972-3976"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding Appearance Concerns in Young People With Cleft Lip ± Palate: A Photo Elicitation Study.","authors":"Julie Davies, Alison Owen, Amy Burton","doi":"10.1177/10556656261418375","DOIUrl":"10.1177/10556656261418375","url":null,"abstract":"<p><p>ObjectiveYoung people (YP) with a cleft lip with or without cleft palate have expressed concerns about their appearance and image-sharing on social media. This study aimed to explore and understand YP's concerns, views, and experiences regarding photographs of themselves.DesignThis was an exploratory qualitative study using photo-elicitation during semi-structured interviews conducted virtually. YP provided 3 photographs of themselves they liked and 3 they did not, which were used to facilitate discussion of their appearance, thoughts, and feelings about their photographs, and social media. Interviews were transcribed and analyzed using Reflexive Thematic Analysis.Patients/ParticipantsThirteen YP aged 16 to 20 years (mean = 17.8), 10 females and 3 males, were recruited via a UK cleft charity. Two had a cleft lip only, 9 had a unilateral cleft lip and palate, and 2 had a bilateral cleft lip and palate.ResultsFour themes were developed: (1) symmetry equals beauty, (2) controlling and curating the image presented to others, (3) acceptance with maturity, and (4) connections can promote empowerment.ConclusionsThe themes highlight the concerns that YP have with their appearance, how they present their self-image to others, and how they can become empowered to embrace their cleft condition and support others. Results suggest cleft services should integrate psychosocial screening, peer support, and appearance-focused interventions to promote confidence and resilience in young people.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3608-3619"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146120776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jo Horton, Adrian P Burgess, Kelsie Smith, Anna Kearney, Sian Davies, Rosanna Samuel, Katie Piggott, Martin Evans
{"title":"Craniofacial Collaboration UK: Long-Term Developmental Outcomes of Single Suture Craniosynostosis.","authors":"Jo Horton, Adrian P Burgess, Kelsie Smith, Anna Kearney, Sian Davies, Rosanna Samuel, Katie Piggott, Martin Evans","doi":"10.1177/10556656261426371","DOIUrl":"10.1177/10556656261426371","url":null,"abstract":"<p><p>ObjectiveThis article explores the long-term developmental outcomes of children diagnosed with single suture craniosynostosis (SSC).Design/participantsData were collected from an opportunity sample of 440 children who received a routine developmental screening assessment in 3 highly specialized craniofacial centers (HSCC) in the United Kingdom between July 2015 and July 2024. All children were assessed with the Ages and Stages Questionnaire-Third Edition (ASQ-3) between 3 and 5 years of age and the Wechsler Abbreviated Scale of Intelligence-Second Edition (WASI-II) at 7 and 10 years of age.ResultsThe majority of children with SSC were in the average range across most developmental and cognitive domains. On the ASQ, 24% of children were found to be \"delayed\" on 1 or more ASQ-3 domains; 8% being found to be delayed on all domains. Delays in fine and gross motor skills were found in early childhood, and in perceptual reasoning skills later on. Using path analysis, it was shown that early delays, especially in fine and gross motor skills, persisted over time and were associated with an increased risk of subtle cognitive deficits in middle childhood. A delay in any 1 developmental domain found before the age of 5 was associated with an IQ difference of around 1 standard deviation below the normative mean on cognitive tests administered in middle childhood.ConclusionsFor most children with SSC, there is no evidence of any impairment in cognitive development. However, for the small minority, delays found in early childhood persisted into middle childhood.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3717-3728"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"IRF6 Gene Polymorphisms Influence the Susceptibility of Nonsyndromic Cleft Lips With or Without Palate: A MOOSE-Compliant Meta-Analysis.","authors":"Rubin Sahu, Subhra Malinee Mishra, Prasad Nalabothu, Syed Altaf Hussain, Lvks Bhaskar","doi":"10.1177/10556656261420470","DOIUrl":"10.1177/10556656261420470","url":null,"abstract":"<p><p>ObjectiveThe present meta-analysis has been conducted with the objective of conducting a precise examination of the association between 6 <i>IRF6</i> gene polymorphisms and the risk of nonsyndromic cleft lip with or without palate (CL ± P) among various ethnic groups.MethodsThe meta-analysis incorporated a total of 53 published case-control studies. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were computed. A leave-1-out sensitivity analysis was conducted, in conjunction with an investigation into publication bias, under the dominant model. Subgroup analysis based on ethnicity was performed.ResultsThe rs642961 was associated with an increased risk (AA + AG vs GG; OR: 1.31; 95% CI: 1.10-1.55; <i>P</i> < .02; <i>I</i><sup>2</sup> = 70%), while rs2235371 significantly reduced risk (AA + AG vs GG; OR: 0.74; 95% CI: 0.60-0.92; <i>P</i> < .007; <i>I</i><sup>2</sup> = 75%) of CL ± P. The remaining single-nucleotide polymorphisms (rs861019, rs2013162, rs2235373, and rs2235375) were not associated with the risk of CL ± P. Subgroup analysis based on ethnicity revealed distinct ethnicity-specific effects, with rs861019 associated with increased CL ± P risk in Caucasians, rs642961 increasing risk in Asians and mixed populations, and rs2235371 reducing risk only in Caucasians.ConclusionWhile <i>IRF6</i> gene rs642961 and rs2235371 were found to be associated with an increased risk of CL ± P in all studies, there was suggestive evidence of ethnic-specific differences, particularly among Caucasian and Asian populations. Although this study lends further support to the notion of an association between CL ± P and the <i>IRF6</i> gene polymorphisms, it is clear that further studies including diverse cohorts are needed to provide fully validated, ethnic- or population-specific insights.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3620-3627"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katerina L Aris, Richard E Kirschner, Emily Hrach, Brandon S Stone
{"title":"A Novel Association Between Mandibulofacial Dysostosis with Microcephaly and Congenital Diaphragmatic Hernia.","authors":"Katerina L Aris, Richard E Kirschner, Emily Hrach, Brandon S Stone","doi":"10.1177/10556656261424482","DOIUrl":"10.1177/10556656261424482","url":null,"abstract":"<p><p>Mandibulofacial dysostosis with microcephaly (MFDM) is a rare craniofacial syndrome due to pathogenic variants in <i>EFTUD2</i>. Affected patients may present with cleft palate, dysmorphic craniofacial features, short stature, microcephaly, developmental delay/intellectual disability, and variable congenital anomalies. Gastrointestinal anomalies include esophageal atresia and tracheoesophageal fistula. Congenital diaphragmatic hernia (CDH) has not been previously reported. Here, we present a novel case of MFDM with CDH in a late preterm female with multiple congenital malformations observed prenatally. Postnatal genetic testing was diagnostic for a heterozygous <i>de novo</i> pathogenic variant in <i>EFTUD2</i>, consistent with a diagnosis of MFDM.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3995-3999"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147285872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Louise Lendt, Magnus Becker, Ketty Andersson, Kristina Klintö
{"title":"Longitudinal Speech Outcomes in Foreign-Born and Native-Born Children in Sweden with Cleft Palate, and Influence of Palatal Surgery Timing.","authors":"Louise Lendt, Magnus Becker, Ketty Andersson, Kristina Klintö","doi":"10.1177/10556656261434727","DOIUrl":"10.1177/10556656261434727","url":null,"abstract":"<p><p>ObjectiveTo compare longitudinal speech outcomes at ages 5 and 10 years in foreign-born and Swedish-born children with cleft palate with or without cleft lip (CP ± L), and assess impact of cleft type, additional diagnosed conditions, sex, and age at completed primary palatal surgery.DesignLongitudinal, registry-based cohort study.SettingRegional public care university hospitals in Sweden.Participants723 children (143 foreign-born, 580 Swedish-born) with CP ± L.InterventionsPrimary and secondary palatal surgery, and speech-language therapy.Main outcome measuresDichotomized outcomes of velopharyngeal competence (VPC), percentage of consonants correct (PCC), and non-oral speech errors, and received secondary palatal surgery and speech-language therapy.ResultsA significantly lower proportion of foreign-born than Swedish-born 5-year-olds had VPC (75% vs. 85%, <i>p</i> = .007), age-appropriate consonant production (25% vs. 57% <i>p</i> < .001), and no non-oral speech errors (67% vs. 84%, <i>p</i> < .001). Speech improved longitudinally, yet a significantly lower proportion of foreign-born children had VPC (86% vs. 94%, <i>p</i> = .002), age-appropriate consonant production (52% vs. 76%, <i>p</i> < .001), and no non-oral errors (82% vs. 93%, <i>p</i> < .001) at 10 years. The difference in VPC at age 5 and in all speech outcomes at age 10 was associated with higher age at primary surgery in foreign-born children. They also had higher rates of secondary palatal surgery (<i>p</i> < .001) and speech-language therapy (<i>p</i> < .001) than Swedish-born peers.ConclusionsLater primary palatal surgery in foreign-born children was associated with poorer speech outcomes at 10 years. Early primary palatal surgery and continued follow-up are essential to optimize speech development.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3857-3873"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13646417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muath S Alassaf, Fatma Dawood Abdulhameed, Ahmad A Othman, Hadeel Khaja, Abdulsamad T Habeeb, Albraa B Alolayan, Mahmoud A Alsulaimani, Faisal F Hakeem
{"title":"Screening for Obstructive Sleep Apnoea in Patients With Cleft Lip and/or Palate in Saudi Arabia.","authors":"Muath S Alassaf, Fatma Dawood Abdulhameed, Ahmad A Othman, Hadeel Khaja, Abdulsamad T Habeeb, Albraa B Alolayan, Mahmoud A Alsulaimani, Faisal F Hakeem","doi":"10.1177/10556656261425656","DOIUrl":"10.1177/10556656261425656","url":null,"abstract":"<p><p>ObjectiveTo screen for obstructive sleep apnea (OSA) in nonsyndromic patients with cleft lip and/or palate in Saudi Arabia and to identify factors associated with positive OSA screening results.DesignCross-sectional analytical study.SettingCleft lip and palate clinic, Madinah, Saudi Arabia.Patients, ParticipantsA total of 231 nonsyndromic patients aged 2 to 18 years with cleft lip and/or palate. Patients with syndromic diagnoses were excluded.InterventionsParticipants and their guardians completed a structured, 37-item interview-based questionnaire administered by the investigator. Responses were recorded through an online form and analyzed after data cleaning.Main Outcome Measure(s)Screening outcomes for OSA risk and associations between OSA status and demographic or clinical variables.ResultsThe mean age of participants was 7.5 ± 3.7 years, and 55.4% were male. Most patients were underweight (70%), followed by those with healthy body mass index (21.2%). No significant differences were found between OSA-positive and OSA-negative groups across demographic or clinical variables, except for the OSA risk score, which was significantly higher in the OSA-risk group.ConclusionsChildren with cleft lip and/or palate may exhibit mild OSA symptoms, including snoring and noisy breathing. Routine clinical screening remains essential to detect early signs of airway obstruction. While polysomnography is the diagnostic gold standard, further research is needed to clarify its correlation with clinical findings in this patient population.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3729-3736"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147311796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What Are the Challenges Facing Comprehensive Cleft Care in Africa? A Qualitative Study Involving Cleft Care Providers Across Africa.","authors":"Ikenna Gerald Isiekwe, Puneet Batra","doi":"10.1177/10556656261428993","DOIUrl":"10.1177/10556656261428993","url":null,"abstract":"<p><p>ObjectiveTo identify the challenges facing comprehensive cleft care in Africa and to propose solutions to some of these challengesDesignA virtual focus group discussion (FGD) was conducted involving 10 cleft care providers from across the African continent. Thematic analysis was used to analyze the collected data.SettingParticipants in the FGD were experienced cleft care providers from across Africa including North Africa, Southern Africa, East Africa, West Africa, Central Africa and a representative of Francophone West Africa.ParticipantsTen experienced cleft care providers from across the African continent, who were selected using a purposive sampling technique, based on their specialty and experience in cleft care.Main outcome measuresChallenges facing comprehensive cleft care in Africa were identified and solutions proffered to some of these challenges.ResultsThe main challenges and solutions were categorized under patients' factors, clinicians' factors and institutional/other factors. Poverty, low level of awareness, insufficient manpower and poor healthcare systems were some of the major recurring challenges. Other unique challenges identified were language barriers affecting access to cleftcare training in Francophone Africa and the brain drain syndrome, which had resulted in the migration of cleftcare manpower from the continent. Improved patient support systems, enhanced manpower training and motivation and improved healthcare systems were some of the solutions suggested<b>.</b>ConclusionThe main challenges identified were shortage of required manpower and institutional and policy challenges, while the proposed solutions ranged from enhanced manpower training and motivation to improved healthcare systems.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3787-3797"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147445826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}