Cleft Palate-Craniofacial Journal最新文献

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Comparison of Dental Relationship and Craniofacial Development in Children With Unilateral Cleft Lip and Palate Treated With/Without Presurgical Nasoalveolar Molding. 术前鼻牙槽成型治疗儿童单侧唇腭裂牙体关系与颅面发育的比较。
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-11-01 Epub Date: 2026-03-12 DOI: 10.1177/10556656261429897
Jie Zheng, Meiqing Ren, Zhengkun Yang, Yangqi Sun, Di Guo, Wenjun Yuan
{"title":"Comparison of Dental Relationship and Craniofacial Development in Children With Unilateral Cleft Lip and Palate Treated With/Without Presurgical Nasoalveolar Molding.","authors":"Jie Zheng, Meiqing Ren, Zhengkun Yang, Yangqi Sun, Di Guo, Wenjun Yuan","doi":"10.1177/10556656261429897","DOIUrl":"10.1177/10556656261429897","url":null,"abstract":"<p><p>ObjectiveTo evaluate long-term effects of presurgical nasoalveolar molding (PNAM) on occlusal relationships and craniofacial development in children with unilateral cleft lip and palate (UCLP) using the 5-year-olds' index and cone-beam computed tomography (CBCT).DesignRetrospective cohort study.SettingTertiary-level Class A specialized stomatological hospital.ParticipantsSixty-four patients with complete UCLP.InterventionsThirty patients underwent PNAM treatment, and 34 patients did not.Main Outcome MeasureCBCT scans were used to assess dental occlusion via the 5-year-old index and to measure craniofacial variables. Intergroup differences were analyzed using the Mann-Whitney <i>U</i> test and the chi-square test, while the correlation between occlusion and craniofacial variables was examined using the Pearson correlation coefficient. A <i>P</i> value of less than .05 was considered statistically significant.ResultsA comparison of 5-year-olds' index scores in the two groups showed median scores of 3.0 (PNAM group) and 3.5 (non-PNAM group), respectively, with no significant difference found. For prognosis, no significant difference in orthognathic surgery need was found, but the PNAM group had a higher nonsurgery rate (60%) versus 50% in the non-PNAM group. In craniofacial development, the PNAM group had significantly longer maxillary length; favorable prognosis group showed smaller SNB angles, shorter mandibular body, larger ANB angles, and longer maxillary length. Correlation analysis showed 5-year-olds' index positively correlated with SNB/mandibular body length, and negatively with ANB/maxillary length.ConclusionsEarly childhood evaluations showed that treatment with/without PNAM in the neonatal period was not a major factor influencing occlusal relationships or craniofacial development in patients with UCLP. Furthermore, correlation between 5-year-olds' index and skeletal morphology in children with UCLP has been confirmed.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3775-3786"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147436963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphometric Analysis of Fossa Navicularis Magna in Patients With Cleft Palate-A Retrospective Cone Beam Computed Tomographic Study. 腭裂患者大椎小舟窝形态计量学分析——回顾性锥束计算机断层扫描研究。
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-11-01 Epub Date: 2026-04-04 DOI: 10.1177/10556656261438890
Thounaojam Sushma Devi, G Subhas Babu, Vidya Ajila, Bidisha Mullick
{"title":"Morphometric Analysis of Fossa Navicularis Magna in Patients With Cleft Palate-A Retrospective Cone Beam Computed Tomographic Study.","authors":"Thounaojam Sushma Devi, G Subhas Babu, Vidya Ajila, Bidisha Mullick","doi":"10.1177/10556656261438890","DOIUrl":"10.1177/10556656261438890","url":null,"abstract":"<p><p>ObjectivesTo evaluate the prevalence, length, width, volume, depth, and shape of fossa navicularis magna (FNM) in patients with cleft lip/palate and comparing with healthy individuals using cone beam computed tomography (CBCT).DesignThis is a retrospective study, cross-sectional study.SettingThis is institutional setting study that utilized archived CBCT scans from the Department of Oral Medicine and Radiology of the institution.Patients and ParticipantsCone beam computed tomography scans of 200 participants aged 10 to 40 years, which comprised of 100 patients with cleft lip and/or palate, and 100 control participants, were used.InterventionFossa navicularis magna was evaluated and compared for its prevalence, length, width, volume, depthand shape among the normal subjects and patients with cleft lip/palate using CBCT.ResultFossa navicularis magna was detected more frequently in cleft (22%) than in control group (9%) and was statistically significant (<i>P</i> = .018). Although mean length, width, depth, and volume values were higher in healthy individuals, only depth was significantly greater in controls, indicating a shallow fossa in patients with cleft lip/palate (<i>P</i> = .033). Morphological distribution (round vs oval) was comparable between groups (<i>P</i> = .99).ConclusionIn the present study, FNM was more common in patients with cleft lip/palate and showed significantly reduced depth. Although oval morphology was slightly more frequent in the cleft group, it was not statistically significant. Awareness of this anatomical variant is important to avoid misinterpretation on CBCT and for better surgical planning.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3911-3916"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147619365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiographic Comparison of Alveolar Bone Grafting in Cleft Lip and Palate: Iliac Crest Versus Mandibular Symphysis. 唇腭裂牙槽骨移植的影像学比较:髂嵴与下颌联合。
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-11-01 Epub Date: 2026-03-29 DOI: 10.1177/10556656261436258
Claudia Resende Leal, Bruno Mariano Ribeiro Braga, José Carlos da Cunha Bastos Júnior, Roberta Martinelli Carvalho, Renato André de Souza Faco, Terumi Okada Ozawa, Rita de Cássia M C Lauris, Araci Malagodi de Almeida, Daniela Gamba Garib
{"title":"Radiographic Comparison of Alveolar Bone Grafting in Cleft Lip and Palate: Iliac Crest Versus Mandibular Symphysis.","authors":"Claudia Resende Leal, Bruno Mariano Ribeiro Braga, José Carlos da Cunha Bastos Júnior, Roberta Martinelli Carvalho, Renato André de Souza Faco, Terumi Okada Ozawa, Rita de Cássia M C Lauris, Araci Malagodi de Almeida, Daniela Gamba Garib","doi":"10.1177/10556656261436258","DOIUrl":"10.1177/10556656261436258","url":null,"abstract":"<p><p>ObjectiveTo compare the radiographic success rates of alveolar bone grafts (ABG) performed using bone harvested from the mandibular symphysis (MS) or the anterior iliac crest (IC). The null hypothesis was that the outcomes would be similar for both groups, regardless of the timing of surgery.DesignRetrospective cohort study with consecutive sampling of 144 periapical radiographs taken 12 months after surgery.SettingA single tertiary craniofacial center.ParticipantsOne hundred forty-four patients with complete unilateral cleft lip and palate (UCLP) and a median age of 14 years were divided into 2 groups according to the donor site.InterventionsA standardized surgical technique was used in the 144 recipient sites. Radiographic outcomes of ABG were classified as success or failure by three blinded evaluators based on the modified Bergland scale.Main Outcome MeasuresThe primary outcome was the radiographic success rate according to the grafting material. Intra- and interrater reliability was evaluated using Kappa statistics. The Mann-Whitney test was applied to compare intergroup age medians. Intergroup comparison of bone graft success rates was performed using the chi-square test (<i>P</i> < .05).ResultsThere was no statistically significant difference in patient age at grafting between the MS and IC groups (<i>P</i> = .116). Both groups had success rate above 90%, with no significant difference between them (<i>P</i> = .190).ConclusionABG using the MS donor site is a viable option for patients with complete UCLP.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3885-3890"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unusual Association of Orofacial Cleft and Finger-Like Skin Appendages With or Without Constriction Rings: A Disorganization-Like Phenotype? 有或没有收缩环的口面裂和指状皮肤附属物的不寻常关联:一种无序样表型?
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-11-01 Epub Date: 2026-03-29 DOI: 10.1177/10556656261437279
Henrique Regonaschi Serigatto, Siulan Vendramini-Pittoli, Priscila Padilha Moura, Luiza Virmond, Vinicius Contrucci Dantas Segarra, José Humberto da Cunha, Carla Rosenberg, Roseli Maria Zechi-Ceide, Nancy Mizue Kokitsu-Nakata
{"title":"Unusual Association of Orofacial Cleft and Finger-Like Skin Appendages With or Without Constriction Rings: A Disorganization-Like Phenotype?","authors":"Henrique Regonaschi Serigatto, Siulan Vendramini-Pittoli, Priscila Padilha Moura, Luiza Virmond, Vinicius Contrucci Dantas Segarra, José Humberto da Cunha, Carla Rosenberg, Roseli Maria Zechi-Ceide, Nancy Mizue Kokitsu-Nakata","doi":"10.1177/10556656261437279","DOIUrl":"10.1177/10556656261437279","url":null,"abstract":"<p><p>The mouse disorganization (Ds) was described in mutant mice with multiple congenital anomalies arising from the 3 germinative layers. The human homologue of Ds was proposed in a case presenting multiple congenital anomalies associated with the unique feature of a finger-like skin appendage. Since then, several cases have been reported suggesting the occurrence of a disorganization-like (Ds-like) phenotype in humans. Here, we report a case series of 7 patients presenting with the association of orofacial clefts and finger-like skin appendages. These cases, despite the similarities with Ds and amniotic band sequence, may represent a distinct condition within the spectrum of Ds-like, as other cases previously reported in the literature.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"4008-4016"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147576303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Anatomy to Application: A Developmental Framework for Suprazygomatic Maxillary Nerve Block in Pediatric Palatoplasty. 从解剖学到应用:儿童腭裂成形术中颧上颌神经阻滞的发展框架。
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-11-01 Epub Date: 2026-04-15 DOI: 10.1177/10556656261422848
Pantip Chitpitaklert, Nav La, Schawanya K Rattanapitoon, Tirayut Veerasatian, Nathkapach K Rattanapitoon
{"title":"From Anatomy to Application: A Developmental Framework for Suprazygomatic Maxillary Nerve Block in Pediatric Palatoplasty.","authors":"Pantip Chitpitaklert, Nav La, Schawanya K Rattanapitoon, Tirayut Veerasatian, Nathkapach K Rattanapitoon","doi":"10.1177/10556656261422848","DOIUrl":"10.1177/10556656261422848","url":null,"abstract":"","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3969-3971"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147693109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
LIMA Protocol for Palatal Fistula Reduction and Early Postoperative Maxillary Morphology in Unilateral Cleft Lip and Palate: A Randomized Controlled Trial. 单侧唇腭裂术后早期腭瘘复位和上颌形态的LIMA方案:一项随机对照试验。
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-11-01 Epub Date: 2026-02-09 DOI: 10.1177/10556656261420473
Kristaninta Bangun, Alberta Jesslyn Gunardi, Vika Tania, Prasetyanugraheni Kreshanti, Julieta Pancawati, Jessica Halim, Clara Menna
{"title":"LIMA Protocol for Palatal Fistula Reduction and Early Postoperative Maxillary Morphology in Unilateral Cleft Lip and Palate: A Randomized Controlled Trial.","authors":"Kristaninta Bangun, Alberta Jesslyn Gunardi, Vika Tania, Prasetyanugraheni Kreshanti, Julieta Pancawati, Jessica Halim, Clara Menna","doi":"10.1177/10556656261420473","DOIUrl":"10.1177/10556656261420473","url":null,"abstract":"<p><p>ObjectiveCompare the incidence of palatal fistula and early postoperative maxillary morphology following cleft palate repair performed using the Lima protocol versus the Two-Flap technique.DesignThis is a double-blind randomized controlled trial. Participants were randomly allocated to treatment groups using a random table. All surgeries were performed by a single surgeon at a single center.SettingA national tertiary referral hospital, January 2022 to December 2024.ParticipantsInfants aged 9 months to 2 years with unilateral cleft lip and palate who had not previously undergone palatal repair. Those with a history of prior palatal surgery or refusal to participate were excluded.InterventionsParticipants underwent palatoplasty using either the Lima protocol (n = 16) or the Two-Flap technique (n = 19).Main Outcome MeasuresIncidence of palatal fistula and changes in early postoperative maxillary morphology during the first 6 months of follow-up, assessed using dental cast measurements.ResultsA total of 39 patients were enrolled, with 35 completing follow-up. Baseline characteristics were comparable between groups. Postoperative palatal fistula occurred in 11% of patients, with no significant difference between the Lima and Two-Flap groups. Early postoperative maxillary morphology parameters showed similar trajectories across groups, except for greater inter-canine width in the Lima group at 6 months (<i>P</i> = .017) and greater palatal length increase in the Two-Flap group between 1 and 6 months post-op (<i>P</i> = .018).ConclusionBoth the Lima and Two-Flap techniques demonstrated comparable efficacy in preventing fistula and preserving early postoperative maxillary morphology. These findings represent short-term outcomes, and longer follow-up is required to evaluate long-term maxillary growth.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3628-3637"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two Decades of Craniosynostosis Surgery: Experience and Outcomes From the National Craniofacial Center in Oman. 二十年颅缝闭锁手术:阿曼国家颅面中心的经验和结果。
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-11-01 Epub Date: 2026-05-04 DOI: 10.1177/10556656261441008
Sondus Al Jadeedi, Khalifa Al Alawi, Yamamh Al Jubori, Sultan Al Shaqsi, Taimoor Al Bulushi
{"title":"Two Decades of Craniosynostosis Surgery: Experience and Outcomes From the National Craniofacial Center in Oman.","authors":"Sondus Al Jadeedi, Khalifa Al Alawi, Yamamh Al Jubori, Sultan Al Shaqsi, Taimoor Al Bulushi","doi":"10.1177/10556656261441008","DOIUrl":"10.1177/10556656261441008","url":null,"abstract":"<p><p>ObjectiveTo evaluate the demographic characteristics, surgical approaches, and short- and long-term outcomes of patients undergoing craniosynostosis (CS) at a national referral center over a 20-year period.DesignRetrospective cohort study.SettingNational Craniofacial Center, Khawlah Hospital.ParticipantsAll patients who underwent surgical correction for CS between January 2004 and December 2023 were included.InterventionsPatients were managed according to a standardized multidisciplinary institutional protocol involving craniofacial plastic surgery and neurosurgery. Surgical interventions included open cranial remodeling procedures-most commonly fronto-orbital advancement-and suturectomy.Main Outcome Measure(s)Demographic data, suture involvement, syndromic association, operative details, perioperative complications, and long-term outcomes were analyzed.ResultsA total of 124 patients were identified; 58.1% were male, and 56.5% had nonsyndromic CS. Multisuture involvement was the most common presentation (39.5%). Most patients underwent surgery between 4 and 12 months of age. Open cranial remodeling was performed in 56.5% of cases, while 11.3% underwent suturectomy. Intraoperative complications were predominantly dural injuries (41.9%), with sagittal sinus injury occurring in 2.4%. Postoperative complications included fever (48.4%) and subgaleal collection (4.8%). There was no perioperative mortality. Long-term follow-up of up to 6 years demonstrated residual cranial deformity in 28.2% and palpable fixation devices in 22.6% of patients.ConclusionsThis 20-year institutional review represents the largest national series of surgically managed CS in Khawlah Hospital. Surgical management achieved favorable outcomes with low morbidity and no mortality. Ongoing multidisciplinary collaboration remains essential to optimize long-term results.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3917-3925"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147822882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring Sleep Behavior and Language Outcomes in Children with Cleft Lip and Palate Using Data from a National Cohort Study. 利用一项国家队列研究的数据探索唇腭裂儿童的睡眠行为和语言结果。
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-11-01 Epub Date: 2026-02-19 DOI: 10.1177/10556656261423833
Stephanie van Eeden, Victoria C P Knowland
{"title":"Exploring Sleep Behavior and Language Outcomes in Children with Cleft Lip and Palate Using Data from a National Cohort Study.","authors":"Stephanie van Eeden, Victoria C P Knowland","doi":"10.1177/10556656261423833","DOIUrl":"10.1177/10556656261423833","url":null,"abstract":"<p><p>ObjectiveTo explore the relationship between sleep behaviors and language development in children with cleft lip and palate (CP ± L).DesignCross-sectional analysis of questionnaire data from a national cohort study.<b>Setting:</b> All participants were treated within a national health service specialist cleft center.<b>Participants:</b> 1990 questionnaires were analyzed. All cleft phenotypes, including 10.2% with Robin Sequence (RS) and 8.5% with syndromic diagnoses, were included.<b>Measures:</b> Sleep outcome measures from parent report included sufficient sleep in a 24-h period and reports of concern about sleep behavior. Language outcome measures included answers to the Ages and Stages Questionnaire (3rd edition) (ASQ-3).ResultsParental concern about sleep was low overall (13.0% at 18 months, 7.9% at 3 years), but higher in children with RS and syndromic diagnoses. At 3 years, parents of children with cleft palate were more likely to be concerned about sleep than those with cleft lip only (P = .009). Reports of sufficient sleep were high (>88% across all ages), but children with RS showed a decline over time. Significant positive correlations were found between sufficient sleep and language outcomes at all ages (τ = .087, P = .004 at 18 months; τ = .131, P = .002 at 3 years; τ = .445, P < .001 at 5 years). At 5 years, this association remained after controlling for confounders (r = .347, P < .001).ConclusionsSleep behaviors were associated with language development in children with CP ± L. These findings highlight the need for longitudinal and interventional studies to better understand the role of sleep on developmental outcomes in this population.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"3677-3689"},"PeriodicalIF":1.3,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13646412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146229501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Using Platelet-Rich Fibrin With an Iliac Crest Bone Graft on Alveolar Bone Formation: A Systematic Review. 富血小板纤维蛋白联合髂骨移植物对牙槽骨形成的影响:一项系统综述。
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-10-22 DOI: 10.1177/10556656261499561
Shankargouda Patil, Sonia Sabu, Shilpa Bhandi, Samuel Thomas, Aayushi Shah, Hayden Dehoyos, Frank W Licari, Charles Miller
{"title":"The Effect of Using Platelet-Rich Fibrin With an Iliac Crest Bone Graft on Alveolar Bone Formation: A Systematic Review.","authors":"Shankargouda Patil, Sonia Sabu, Shilpa Bhandi, Samuel Thomas, Aayushi Shah, Hayden Dehoyos, Frank W Licari, Charles Miller","doi":"10.1177/10556656261499561","DOIUrl":"https://doi.org/10.1177/10556656261499561","url":null,"abstract":"<p><p>ObjectiveAlveolar bone grafting in individuals with cleft lip and/or palate is typically performed using the iliac crest as the donor site. Platelet-rich fibrin is a concentrate rich in growth factors that can promote bone formation. This review evaluates the effect of using this concentrate along with alveolar bone grafts on bone formation in people with cleft lip and/or palate.DesignThis systematic review was conducted following the PRISMA guidelines, and PubMed (MEDLINE), Scopus, Embase, and Web of Science were searched with appropriate search terms. Data were exported to EndNote Online, and duplicates were removed. After screening, full-text articles were retrieved, and only those meeting the inclusion criteria were further assessed. Data were extracted, and the methodological quality of the articles was appraised using the Cochrane Risk of Bias tool.SettingNot applicable.PatientsIndividuals with cleft lip and/or palate.InterventionsAlveolar bone grafting using the iliac crest.Main outcome measureDetails on volume, percentage of newly formed bone, density, height, and width of the bone over time in the cleft lip and/or palate.ResultsOf 116 articles retrieved from the databases, 5 were included in the review. All studies indicated better outcomes when using platelet-rich fibrin with the graft, although the results were not always statistically significant. Methodological concerns were noted across all studies.ConclusionPlatelet-rich fibrin may enhance bone formation at the alveolar cleft site when used with iliac crest grafts. However, more rigorous long-term studies and clinical trials are needed to obtain definitive evidence.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656261499561"},"PeriodicalIF":1.3,"publicationDate":"2026-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149247080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Utility of Velopharyngeal MRI in Children With Unexplained Velopharyngeal Insufficiency. 腭咽MRI对不明原因腭咽功能不全儿童的诊断价值。
IF 1.3 4区 医学
Cleft Palate-Craniofacial Journal Pub Date : 2026-10-21 DOI: 10.1177/10556656261497973
Emily K Sherrod, Jonathan Black, Kazlin N Mason
{"title":"Diagnostic Utility of Velopharyngeal MRI in Children With Unexplained Velopharyngeal Insufficiency.","authors":"Emily K Sherrod, Jonathan Black, Kazlin N Mason","doi":"10.1177/10556656261497973","DOIUrl":"10.1177/10556656261497973","url":null,"abstract":"<p><p>ObjectiveTo explore the utility of velopharyngeal MRI in contributing additional diagnostic information for patients with velopharyngeal insufficiency (VPI) of unknown etiology.DesignRetrospective cohort study.SettingTertiary children's hospital.ParticipantsChildren with clinically significant VPI without a confirmed etiology.InterventionsStandardized perceptual speech assessment with nasometry, non-sedated MRI, and multidisciplinary review for treatment planning.Main Outcome MeasuresMRI-informed etiologic classification, anatomic and functional contributors to VPI, and management recommendations.ResultsAmong 89 children, six (6.7%) presented with clinically significant VPI of unknown etiology on routine examination. MRI identified occult submucous cleft palate or atypical levator veli palatini morphology in five (83.3%) and adenoid-supported VP closure in three (50%). Involution was expected to unmask increased pharyngeal depth in two (33.3%). MRI supported patient-specific recommendations for speech therapy, surgical interventions, and longitudinal monitoring.ConclusionsMRI provided clinically meaningful diagnostic information beyond routine examination and informed management decisions for children with VPI.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656261497973"},"PeriodicalIF":1.3,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13693508/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149240249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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