Cleft Palate-Craniofacial Journal最新文献

{"title":"\"A Retrospective Evaluation of the Impact of Prenatal Diagnosis of Facial Clefts. Does Prenatal Diagnosis Matter?\"","authors":"Alyssa Valenti, Weijia Fan, Paul Asadourian, Vikash Modi, Thomas A Imahiyerobo","doi":"10.1177/10556656241272449","DOIUrl":"10.1177/10556656241272449","url":null,"abstract":"<p><p>BackgroundWith the advent of improved prenatal detection, some patients with facial clefting are diagnosed prenatally while others are diagnosed postnatally. There is limited data regarding the utility of prenatal diagnosis and how this affects care of patients with facial clefts.Methods and MaterialsA retrospective chart review was performed. Children with incomplete demographic data and those with syndromic conditions were excluded. The data were analyzed via Fisher's exact tests and Kruskal-Wallis tests (p < 0.05).Results106 patients met inclusion criteria. Facial clefting was diagnosed prenatally at different frequencies depending on type of facial cleft- patients with cleft palate alone were less likely to be identified prenatally (p < 0.0001). Patients diagnosed prenatally were seen by craniofacial specialists at an earlier age compared to those diagnosed after birth (0.27 months vs 0.7 months, p < 0.001). Similarly, those with prenatal diagnosis underwent surgery at a younger age compared to those who were diagnosed postnatally (median: 3.6 months vs 10.67 months, p < 0.001) and experienced shorter lag time (median: 3.4 months vs 8.4 months, p = 0.027) from consultation to surgery. Importantly, prenatal diagnosis resulted in pre-surgical therapy more often than in children diagnosed postnatally (86% vs 22.2%, p < 0.001).ConclusionsOur data suggests that patients with prenatal diagnosis of facial clefts were more likely to undergo pre-surgical therapy, presented to a craniofacial specialist at an earlier age, underwent surgery at an earlier age, and experienced less lag time between initial visit and surgery. More study is warranted to improve protocols for prenatal diagnoses to improve surgical outcomes.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1728-1732"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate Impact of a Patient-Reported Outcome Measure Visual Dashboard on Cleft lip and Palate Care Provision.","authors":"Nicolette T Bushman, Tyler Nguyen, Joseph Incorvia, John G Meara, Ingrid M Ganske, Carolyn Rogers-Vizena","doi":"10.1177/10556656241272450","DOIUrl":"10.1177/10556656241272450","url":null,"abstract":"<p><p>Cleft-related Patient Reported Outcome Measure (PROM) results were formatted into graphical displays for children scoring below the 25^th percentile on one or more scales. Reports were piloted in a multidisciplinary clinic where providers reviewed them, and their impact was qualitatively recorded. Graphical PROM reports informed discussions, led to treatment plan changes, and raised awareness of unmet psychosocial needs. Because of the success of this quality improvement pilot, visual PROM reports will become a regular part of our multidisciplinary cleft care. More broadly, graphical PROM data display facilitates better understanding of the patient's perspective and leads to more informed visits.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"1808-1815"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anxiety in Caregivers of Chinese Children Under 3 Years Old with Cleft Lip or Palate.","authors":"Yuanling Meng, Meijun Du, Jialu Song, Yixing Liu, Yiting Cai, Haoyang Wu, Jiali Chen, Renjie Yang, Ting Chi, Caixia Gong, Bing Shi, Hanyao Huang, Yong Lu","doi":"10.1177/10556656251382838","DOIUrl":"https://doi.org/10.1177/10556656251382838","url":null,"abstract":"<p><p>ObjectivesThis study compared anxiety between Chinese caregivers of children with non-syndromic cleft lip (CL) or cleft palate (CP) at the time of their first surgery and control group as well as identifying factors associated with caregiver anxiety.DesignRetrospective, observational cohort study.SettingDepartment of Cleft Lip and Palate in West China Hospital of Stomatology, Sichuan University.ParticipantsCaregivers of children under 3 years old.Main Outcome MeasuresThe 7-item Generalized Anxiety Disorder Scale (GAD-7).ResultsCaregivers were mostly married mothers aged 19-35 years in the control (<i>n</i> = 131), CL (<i>n</i> = 132), or CP (<i>n</i> = 147) groups. Mean GAD-7 scores were 4.90 ± 4.53, 3.74 ± 3.95, and 4.82 ± 4.64 for the control, CL, and CP groups, respectively. The only differences were lower anxiety for the CL group compared to controls (<i>P</i> = .028) and to the CP group (<i>P</i> = .038). Most caregivers reported no anxiety (control 50.38%, CL 65.15%, CP 53.74%) or mild anxiety (control 39.69%, CL 27.27%, CP 31.29%). More CL caregivers exhibited no anxiety compared to controls (65.15% vs. 50.38%), while more CP caregivers exhibited moderate anxiety compared to controls (12.24% vs. 3.82%). Higher GAD-7 scores were associated with having fewer children for CL caregivers, and with younger age and lower education for CP caregivers.ConclusionAt the time of first surgery, most Chinese caregivers of children with CL/CP had no to low anxiety. Additional psychosocial support may benefit the 8% to 15% of caregivers of children with a cleft who had moderate or severe anxiety.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251382838"},"PeriodicalIF":1.3,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Pharyngeal Airway Dimensions Between Nonsyndromic Cleft Lip and Palate Patients and Healthy Controls: A Systematic Review and Meta-Analysis.","authors":"Farzaneh Ahrari, Neda Eslami, Erfan Bardideh, Mahsa Ghorbani, Maryam Forghani, Arya Gazerani","doi":"10.1177/10556656251325095","DOIUrl":"https://doi.org/10.1177/10556656251325095","url":null,"abstract":"<p><p><i>Objective</i>This study aimed to evaluate the dimensions of pharyngeal airways among nonsyndromic cleft lip and palate (CLP) patients, comparing them with a healthy control group.<i>Design</i>Systematic review and meta-analysis.<i>Patients and Exposures</i>Patients with CLP.<i>Comparison</i>Patients without CLP.<i>Main Outcome Measures</i>Primary outcomes included the volume of different pharyngeal sections, total pharyngeal airway volume, and the minimum cross-sectional area of the pharynx. Secondary outcomes were to assess the effect of cleft type, age, and sex on pharyngeal airways.<i>Results</i>A comprehensive search of MEDLINE, Web of Science, EMBASE, Scopus, and Cochrane's CENTRAL (up to August 2023) identified 39 clinical studies meeting PECO criteria, with their risk of bias assessed using the Risk of Bias in Non-randomized Studies of Exposure tool. Of these, 33 were included in a random-effects inverse variance meta-analysis. The results indicated that nonsyndromic CLP patients demonstrated a significant reduction in the volumes of total pharyngeal airway (<i>P</i> = .01), velopharynx (<i>P</i> < .001), and oropharynx (<i>P</i> < .001) compared to healthy individuals. No significant differences were observed between groups regarding nasopharynx (<i>P</i> = .60) and hypopharynx (<i>P</i> = .36) regions. The minimum cross-sectional area was significantly smaller in CLP patients compared to healthy individuals (<i>P</i> = .02). The cleft type, age, and sex showed no significant effects on the extent of dimension reduction in pharyngeal airways (<i>P</i> > .05).<i>Conclusion</i>The pharyngeal airway dimensions, particularly in the middle sections (velopharynx and oropharynx), are significantly reduced in nonsyndromic CLP patients when compared to the healthy controls. Variations in CLP type, patient age, and sex do not significantly influence this decrease in dimensions.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251325095"},"PeriodicalIF":1.3,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are There Morphophysiological Airway Alterations in Syndromic Craniosynostosis? A 3D Computed Tomography and CFD Analysis.","authors":"Michele Garcia-Usó, Amelia Fischer Drake, Luiz André Pimenta, Marcela Cristina Garnica-Siqueira, Thiago Henrique Dos Santos Antunes Albertassi, Cristiano Tonello, Sérgio Henrique Kiemle Trindade, Ivy KiemleTrindade-Suedam","doi":"10.1177/10556656241302550","DOIUrl":"https://doi.org/10.1177/10556656241302550","url":null,"abstract":"<p><p>ObjectivesCharacterize the upper airways (UAW) in individuals with syndromic craniosynostosis (SCS) using computed tomography scans and correlate with the airflow dynamics and craniofacial pattern.DesignObservational, cross-sectional study.SettingTertiary craniofacial center.IndividualsTwenty-nine individuals were included, divided in 2 groups: CON (n = 19; 21.2 ± 3.7 y), individuals with no craniofacial anomalies and no UAW morphological alterations, and SCS (n = 10; 22.1 ± 5.1 y) individuals with SCS prior to maxillomandibular surgery.InterventionsVolume (V, cm³) and minimal cross-sectional area (mCSA, mm²) was calculated (Mimics, Belgium). Computational fluid dynamics (ANSYS, EUA) was performed and flow (F, L/min), pressure (P, Pa), and resistance (R, Pa/[L/min]) were calculated. Cephalometric analysis (SNA[^o]), ANB[^o], Ba-S-N[^o]) was also assessed (Dolphin Imaging, USA).Main OutcomeThe morphophysiology of the UAW in SCS individuals was severely impaired compared with the CON group.ResultsThe SCS group exhibited significant volumetric reduction in the total UAW (-29%), nasal cavity (-21%), and pharynx (-37%) compared with the CON group. The mCSA was 57% smaller in the SCS group. CFD simulations demonstrated decreased flow (-9%), increased pressure (136%), and resistance (156%) in the SCS group. UAW resistance presented a strong positive correlation with mCSA (CON: <i>r</i> = 0.77 / SCS: <i>r</i> = 0.88). Cephalometric findings revealed significant differences between CON and SCS, with the SCS group exhibiting values outside the normal range.ConclusionThe UAW of individuals with SCS was anatomically and functionally impaired, suggesting a significant risk for obstructive sleep apnea.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656241302550"},"PeriodicalIF":1.3,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Staged Management of Alveolar Cleft in a Young Adult Using Combination of Local Flap, Tongue Flap, and Iliac Graft.","authors":"Sahand Samieirad, Sara Pilehvar, Shayan Yousefi, Saleh Dadmehr, Sina Samieirad, Ricardo Grillo","doi":"10.1177/10556656251378996","DOIUrl":"https://doi.org/10.1177/10556656251378996","url":null,"abstract":"<p><p>This case report details a 2-stage protocol for treating alveolar clefts, utilizing autogenous bone grafts and tongue flap techniques. This case demonstrates the value of a meticulously tailored surgical protocol (autogenous iliac bone grafting, tongue flaps, and a 2-stage approach) for achieving functional and aesthetic restoration in complex adult alveolar cleft defects, based on patient-specific anatomical traits and the extent of the defect. Further comparative research could explore long-term outcomes of such staged approaches versus single-stage repairs in similarly complex adult cases.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251378996"},"PeriodicalIF":1.3,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden of Travel is not Associated with Adherence to Follow-up Appointments - A Call for Centralization of Cleft Care in Germany.","authors":"Anna Katharina Sander, Dominik Deffner, Elisabeth Grau, Fabian Fenske, Bernd Lethaus, Andreas M Fichter","doi":"10.1177/10556656251380543","DOIUrl":"https://doi.org/10.1177/10556656251380543","url":null,"abstract":"<p><p>ObjectiveThe German system of care for patients with cleft lip and/or palate (CL/P) is fragmented. An argument against centralization is that the higher burden of travel for patients in remote and rural areas would reduce appointment adherence and subsequent care outcomes. Our objective was to test the association of travel burden and adherence and outline potential benefits of centralized cleft care.DesignFollow-up appointments June 2005 to August 2020 were retrospectively analyzed for patients with CL/P in a large German tertiary care center. Distance to care center and travel time by car/public transportation were calculated using Google Maps. Demographic characteristics included population density, degree of urbanization, and average disposable income per capita of the municipality of origin. Multiple regression models including flexible spatial function learning assessed associations with follow-up appointment adherence.ResultsPatients (n = 1140) had 9447 scheduled appointments with a 48.2% attendance rate. Distance to the clinic (M = 85.19 ± 75.12 km, range 0.45-536), travel time (M = 71.18 ± 48.5 min, range 2-330), population density (725.32 ± 807.82 inhabitants/km², range 14-4861), and lower average income (20,993.38 ± 1220.72 Euro, range 14,521-32,348.83) were not associated with appointment attendance. Patients from more rural areas were slightly more likely to attend check-ups (p = 0.027, 95% CI [0.016, 0.212]).ConclusionThe burden of travel to the clinic was not associated with attending follow-up appointments for patients with CL/P. These findings challenge a common assumption about attendance and warrant further multi-center studies to inform policy decisions for restructuring cleft care in Germany.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251380543"},"PeriodicalIF":1.3,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Correlation Between Orofacial Cleft Birth Prevalence and Residential Altitude: A Global, Ecological Study.","authors":"Xin-Ru Li, Lei-Ming Cao, Wenting She, Zhongzhi Jin, You-Jian Peng","doi":"10.1177/10556656251378598","DOIUrl":"https://doi.org/10.1177/10556656251378598","url":null,"abstract":"<p><p>ObjectThis study aims to analyze the correlation between orofacial cleft (OFC) birth prevalence and residential altitude from a global perspective, providing more evidence for the development of early screening and prevention policies for OFC, particularly in high-altitude regions.DesignThe birth prevalence of OFC, summary exposure value of associated risk factors, and Socio-demographic Index data were extracted from the Global Burden of Disease Study 2021. Geographic altitude (GA) and global altitude-population data were extracted from published data. A novel Population Altitude Index (PAI) was developed to describe the altitude at which a country's population is primarily concentrated. Spearman correlation coefficient (<i>R_s</i>), multinominal logistic regression, partial correlation analysis, Mann-Whitney <i>U</i> test, and paired <i>t</i> test were employed to analyze the relationships between OFC birth prevalence, GA, PAI, and other related factors. Sensitivity analysis was performed using the generalized linear model. The population attributable fraction was used to assess the contribution of high residential altitude to the birth prevalence of OFC.ResultsMann-Whitney <i>U</i> test and paired <i>t</i> test indicated a statistical difference between GA and PAI (<i>P</i> < .05). Orofacial cleft birth prevalence showed a moderate positive correlation with PAI (<i>R_s</i> = 0.31, <i>P</i> < .05), stronger than with GA (<i>R_s</i> = 0.21, <i>P</i> < .05). Partial correlation analysis, multinominal logistic regression, and generalized linear model confirmed PAI's independent association with OFC birth prevalence after adjusting for other risk factors. A PAI threshold of 375 m yielded the largest intergroup difference (Cohen <i>d</i> = -0.65). The estimated population attributable fraction for OFC birth prevalence in regions with a PAI >375 m was 9.9% (lower: 4.7%, upper: 14.1%).ConclusionResidential altitude, particularly when assessed by PAI, is positively associated with national and regional level OFC birth prevalence. The PAI may serve as a valuable index for future altitude-related epidemiological studies.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251378598"},"PeriodicalIF":1.3,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association of Neighborhood Disadvantage with Surgical Outcomes and Follow-up Adherence in Patients with Cleft Palate.","authors":"Daniel Y Chu, Aidan W O'Shea, Jessieka T Knazze, Chloe S Lam, Alexandra D Center, Manasa H Kalluri, Jessica D Blum, Ellen C Via, Catharine B Garland, Daniel Y Cho","doi":"10.1177/10556656251381640","DOIUrl":"https://doi.org/10.1177/10556656251381640","url":null,"abstract":"<p><p>ObjectiveTo assess the relationship between neighborhood-level social disadvantage, as measured by Area Deprivation Index (ADI) and Childhood Opportunity Index (COI), and postoperative outcomes and follow-up care after primary or secondary cleft palate repair.DesignRetrospective cohort study.SettingAcademic tertiary care center.PatientsPediatric patients with cleft palate with or without cleft lip (CP ± L).InterventionsPrimary palatoplasty, revision palatoplasty, or closure of oronasal fistula.Main outcome measuresPostoperative complications and clinic follow-up adherence.ResultsA total of 244 patients were included in the study. Among all patients, there was only a moderate correlation between patients' ADI and COI quintiles (R² = 0.465, <i>P</i> < .001). In patients undergoing primary palatoplasty, greater ADI neighborhood deprivation was significantly associated with a greater number of no-show (<i>P</i> = .011) and cancelled (<i>P</i> = .025) clinic appointments. In patients undergoing revision palatoplasty, greater ADI neighborhood deprivation was significantly associated with higher rates of postoperative complications (<i>P</i> = .016) and a greater number of no-show clinic appointments (<i>P</i> = .036). Greater COI disadvantage was associated with significantly higher rates of hospital readmission (<i>P</i> = .049) and fewer cancelled clinic appointments (<i>P</i> = .049) in revision palatoplasties. Neighborhood disadvantage was not predictive of any oronasal fistula repair postoperative outcomes, follow-up adherence, or patient characteristics at surgery.ConclusionsNeighborhood-level social disadvantage indices are predictive of suboptimal surgical outcomes and follow-up adherence in patients undergoing cleft palate surgery and could be used to identify patients who may benefit from additional clinic outreach and support.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251381640"},"PeriodicalIF":1.3,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What Factors Affect Safe Bedside Extubation After Mandibular Distraction?","authors":"Cory M Resnick, Andrew J Deek, Ryan Caprio, Snigdha Jindal, Faye Evans, Raymond Park","doi":"10.1177/10556656251381160","DOIUrl":"https://doi.org/10.1177/10556656251381160","url":null,"abstract":"<p><p>ObjectiveThere is no universal protocol for extubation following mandibular distraction osteogenesis (MDO) surgery in infants with Robin sequence (RS). The aims of this study were to identify the frequency and contributing factors for reintubation after MDO, to help determine the optimal setting for planned extubation.DesignThis is a retrospective observational study of patients with RS managed with MDO during their first year of life from 2013 to 2021.Main Outcome MeasuresThe primary outcome variable was the need for reintubation <24 h after extubation. A secondary outcome was the frequency of oxygen saturation <95% after extubation.ResultsFifty-two subjects were included. Of these, 31 (59.6%) were male, 43 (82.7%) had a cleft palate, 19 (36.5%) were syndromic, and 24 (46.2%) had ≥1 comorbidity. Extubation was at 3.6 ± 2.4 days after surgery and 1 patient (1.9%) required reintubation. Forty-one (78.8%) had ≥1 transient oxygen desaturation managed with supplemental oxygen (<i>n</i> = 25, 61%) or continuous positive airway pressure (<i>n</i> = 16, 39%). Increased risk for postextubation respiratory events was associated with Stickler syndrome (<i>P</i> = .01), musculoskeletal, neurologic, or endocrine comorbidities (<i>P</i> < .001), low birthweight (<i>P</i> = .044), and high preoperative obstructive Apnea-Hypopnea Index (<i>P</i> = .037).Conclusions and RelevanceReintubation was rare and minor postextubation oxygen desaturations, while common, were readily treated utilizing standard intensive care unit protocols. We conclude that most infants with RS can be safely extubated in their care unit following MDO. This minimizes medical resources, decreases hospital charges, and simplifies patient management compared to returning to the operating room for extubation.</p>","PeriodicalId":49220,"journal":{"name":"Cleft Palate-Craniofacial Journal","volume":" ","pages":"10556656251381160"},"PeriodicalIF":1.3,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}