Iranian Journal of Public Health最新文献

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Physical Activity Status and Body Composition of Adolescents with Borderline Intellectual Functioning in South Korea. 韩国边缘智力功能青少年的体育活动状况和身体组成。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Jong Sung Kim, Woo Yeul Baek
{"title":"Physical Activity Status and Body Composition of Adolescents with Borderline Intellectual Functioning in South Korea.","authors":"Jong Sung Kim, Woo Yeul Baek","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1467-1468"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Environmental Scanning Model in Health System and Implementation Steps: A Scoping Review. 卫生系统中的环境扫描模式及实施步骤:范围审查。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Khalil Kalavani, Mohammad Hossein Mehrolhassani, Abdurrahim Pedram, Abbas Vosoogh-Moghaddam, Reza Dehnavieh
{"title":"Environmental Scanning Model in Health System and Implementation Steps: A Scoping Review.","authors":"Khalil Kalavani, Mohammad Hossein Mehrolhassani, Abdurrahim Pedram, Abbas Vosoogh-Moghaddam, Reza Dehnavieh","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Various studies have highlighted the usefulness of environmental scanning in assessing community needs and developing programs and policies. We aimed to find the most practical model of using such scanning in the healthcare literature.</p><p><strong>Methods: </strong>We conducted a scoping review based on the PRISMA guideline to ensure a comprehensive and systematic approach in 2023. To develop a comprehensive search strategy, we worked with experienced librarians and the research team. We then completed a search of five electronic databases, including Web of Science, PubMed, Scopus, Cochrane, and Embase databases. Two independent reviewers screened titles, abstracts, and full-text articles to select studies that met our inclusion criteria. The data was then analyzed and presented in a tabular format to facilitate easy interpretation and understanding.</p><p><strong>Results: </strong>We retrieved 7243 articles from various databases and sources. After removing 2755 articles due to duplication, we excluded 4380 more articles during the title and abstract screening phase. In the full-text review process, we ruled out an additional 103 articles. Finally, only 5 articles that were directly relevant to the study were included. The model that Bednar and colleagues have in their article is the latest model. Most studies propose six main steps to conduct an environmental survey in the healthcare system.</p><p><strong>Conclusion: </strong>Since the most important task of managers and policy makers of the health system is to make decisions, they can use our proposed model to collect, analyze and interpret data, identify important patterns and trends so that they can make evidence-based decisions.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1261-1271"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adjunctive Drug-Loaded Gel in the Treatment of Periodontitis: A Systematic Evaluation and Meta-Analysis. 治疗牙周炎的辅助药物凝胶:系统评估与元分析》。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Zhige Li, Xin Yang, Jiao Wang, Ziyang Qin, Yucheng Meng, Baoping Zhang
{"title":"Adjunctive Drug-Loaded Gel in the Treatment of Periodontitis: A Systematic Evaluation and Meta-Analysis.","authors":"Zhige Li, Xin Yang, Jiao Wang, Ziyang Qin, Yucheng Meng, Baoping Zhang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>This meta-analysis aimed to systematically investigate the efficacy of drug-loaded gel adjuncts in the treatment of periodontitis.</p><p><strong>Methods: </strong>A comprehensive search was conducted in six databases, i.e., the China National Knowledge Infrastructure, WanFang Data, VIP Chinese Science and Technology Periodical Database, China Biology Medicine Disc, Cochrane Library, PubMed, and Web of Science, from the inception until Jun 2023. The search focused on randomized controlled trials that examined the application of drug-loaded gels in the treatment of periodontitis. Periodontal probing depth and clinical attachment level were the primary and secondary outcomes, respectively. Stata 15.0 and Review Manager 5.4 were employed to perform the meta-analysis using the selected articles that met the predefined criteria.</p><p><strong>Results: </strong>This study included 16 randomized controlled trials involving 1146 participants. Subgroup analyses based on the follow-up period revealed that the gel-based drug-assisted subgingival root planning intervention had more favorable effects on periodontal probing depth (standardized mean difference=0.50, 95% confidence interval=[0.32, 0.68], <i>I</i> <sup><i>2</i></sup> =56.0%, <i>P</i>=0.001) and clinical attachment level (standardized mean difference=0.47, 95% confidence interval=[0.29, 0.66], <i>I</i> <sup><i>2</i></sup> =57.0%, <i>P</i>=0.0007) than the subgingival root planning intervention alone. However, subgroup analysis based on the action mechanism of gel drugs showed no statistically significant differences in periodontal probing depth and clinical attachment level between groups.</p><p><strong>Conclusion: </strong>The application of the drug-loaded gel as adjunctive therapy for periodontitis effectively reduced periodontal probing depth and promoted clinical attachment level recovery. The findings provide evidence-based support for the efficacy, security, and rational use of drug-loaded gel in the treatment of periodontitis.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1246-1260"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Presentation and WES Analysis of a Large Iranian Pedigree in Five Successive Generation Affected to Sever Multiple Synostosis 2 (SYNS2, Farhud Type). 伊朗一个连续五代受严重多发性骨骺2(SYNS2,Farhud型)影响的大型父系的临床表现和WES分析。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Dariush D Farhud, Marjan Zarif-Yeganeh, Hajar Arian, Majid Kashi, Tayebeh Rezaee
{"title":"Clinical Presentation and WES Analysis of a Large Iranian Pedigree in Five Successive Generation Affected to Sever Multiple Synostosis 2 (SYNS2, Farhud Type).","authors":"Dariush D Farhud, Marjan Zarif-Yeganeh, Hajar Arian, Majid Kashi, Tayebeh Rezaee","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Bone Morphogenetic Proteins and the related Growth and Differentiation Factors (GDFs) are much conserved signaling proteins. GDF5 is pivotal for skeletal development. Several skeletal dysplasia and malformation syndromes are known as a result of mutations in <i>GDF5</i>. Multiple Synostosis Syndrome2 (SYNS2) is characterized by tarsal-carpal coalition, humeroradial synostosis, brachydactyly, and proximal symphalangism. In this study, we analyzed a large Iranian pedigree affected with a new type of SYNS2 (Farhud Type) in five successive generations.</p><p><strong>Methods: </strong>In this family-based study (1982-2022), Genetic linkage analysis of the pedigree (58affected, 62healthy) excluded the locus on chromosome 17q21-q22 in our previous study. Thus, we focused on 20q11.22 locus and <i>GDF5</i> gene. Genetic investigations were performed on 16 patients with SYNS2 and 40 healthy individuals.</p><p><strong>Results: </strong>Whole-exome-sequencing results identified a heterozygote missense mutation in exon2 of <i>GDF5</i> (NG_008076.1:g.9239G>A, NM_000557.2:c.1424G>A, S475N, rs121909347). This mutation was found in all patients but not in the unaffected individuals. This missense mutation is notable because S475 is strictly conserved among different species, and it is located in a highly conserved and active mature domain of GDF5 (phyloP100way=7.64). The corresponding defect in GDF5 may have unknown interaction with normal active 3<sup>rd</sup> and 4<sup>th</sup> structure of the product. Further bioinformatics study (amino acid multiple alignments) showed that the S475 is a much-conserved residue in many different species.</p><p><strong>Conclusion: </strong>These results introduce a new role of <i>GDF5</i> in pathogenesis of a SYNS2 (Farhud Type), considered in genetic counseling, prenatal diagnosis, and as a potential target for molecular therapy, if possible.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1381-1393"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determinants of Quality of Life in Serbian Infertile Couples. 塞尔维亚不育夫妇生活质量的决定因素。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Milena Zlatanovic, Ardea Milidrag, Marija Sorak, Sanja Kocic, Aleksandar Višnjić, Mile Despotović, Teodora Safiye, Milena Despotović, Christos Alexopoulos, Svetlana Radević
{"title":"Determinants of Quality of Life in Serbian Infertile Couples.","authors":"Milena Zlatanovic, Ardea Milidrag, Marija Sorak, Sanja Kocic, Aleksandar Višnjić, Mile Despotović, Teodora Safiye, Milena Despotović, Christos Alexopoulos, Svetlana Radević","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to examine the quality of life and the factors that determine the quality of life of infertile couples.</p><p><strong>Methods: </strong>The research was conducted as a cross-sectional study at the Gynecology and Obstetrics Clinic \"Narodni Front\" in Belgrade, the Special Gynecology Hospital \"Ferona\" in Novi Sad, the Special Hospital for the Treatment of Sterility and In Vitro Fertilization \"Spebo Medikal\" in Leskovac and the General Hospital in Valjevo, Serbia in 2022, on a sample of 378 infertile couples. The data were collected by means of a questionnaire, the integral part of which is the standardized FertiQoL scale. Independent <i>t</i>-test and one-way ANOVA were used to determine differences. A value of <i>P</i><0.05 was considered statistically significant.</p><p><strong>Results: </strong>Women achieve a significantly lower score on the quality of life questionnaire (69.34±11.05) compared to men (73.96±9.87). Women exhibit significantly lower scores in the area of physical, emotional and social functioning (<i>P</i><0.05). Men who live in the countryside show a lower quality of life score in the emotional (<i>P</i>=0.029) and social (<i>P</i>=0.042) domains. In addition, men over 40 years of age and with a high level of education have a lower quality of life (<i>P</i>=0.08).</p><p><strong>Conclusion: </strong>Women have a lower quality of life, as do men from rural areas and over 40 years of age. A multi-disciplinary approach and community education, as well as the provision of social support with a special emphasis on emotional and material support, would significantly contribute to improving the quality of life of infertile couples.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1322-1331"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender and Age Discrepancies of Lifestyle Indices Related to Metabolic Syndrome among Iranian Aging Population. 伊朗老年人群中与代谢综合征相关的生活方式指数的性别和年龄差异。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Ali Dehghani Ahmadabad, Leila Jahangiry, Mahdieh Abbasalizad Farhangi, Haniyeh Farajiazad, Eesa Mohammadi
{"title":"Gender and Age Discrepancies of Lifestyle Indices Related to Metabolic Syndrome among Iranian Aging Population.","authors":"Ali Dehghani Ahmadabad, Leila Jahangiry, Mahdieh Abbasalizad Farhangi, Haniyeh Farajiazad, Eesa Mohammadi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>We aimed to investigate the relationship between lifestyle status and metabolic syndrome (MetS) components across gender and age groups of the older population, specifically focusing on identifying the association between MetS and lifestyle factors in classified age groups in older individuals.</p><p><strong>Methods: </strong>Overall, 582 older people with MetS in Yazd (Iran) urban primary health care centers were randomly included from 10 health centers and invited to participate in the study in 2022. During the phone invitation, eligible interested people were asked to refer to health care centers for clinical assessments by trained health researchers. MetS components, dietary intakes using validated frequency food questionnaire, and physical activity by International physical activity questionnaire (IPAQ-short form) were measured.</p><p><strong>Results: </strong>Women with Mets under 75 yr had significantly higher BMI, weight, and FBS than men and men had significantly higher WC than women. Among patients over 75 yr old, women had significantly higher weight than men had and lower WC and lower HDL_C than men. There were significant differences between gender groups of the aging patient under 75 yr old in terms of vigorous physical activity, total metabolic equivalent of activity, total fat intake, PUFA, and sodium intake, with men reporting level of mentioned lifestyle factors than women.</p><p><strong>Conclusion: </strong>There were significant gender differences between two aged groups (>75 and <75 yr old) of patients for MetS components and lifestyle risk factors. Weight and WC showed noteworthy gender differences, with variations in both age groups.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1437-1445"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the Causes of Neonatal Mortality: An Umbrella Review. 调查新生儿死亡原因:综述。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Elham Amini, Mohammad Heidarzadeh, Leila Ahmadian, Shahram Ariafar, Mohammadreza Amiresmaili
{"title":"Investigating the Causes of Neonatal Mortality: An Umbrella Review.","authors":"Elham Amini, Mohammad Heidarzadeh, Leila Ahmadian, Shahram Ariafar, Mohammadreza Amiresmaili","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Neonatal mortality remains a critical global challenge, with preventable instances prevailing. The initial stride in mitigating neonatal mortality involves elucidating its underlying causes.</p><p><strong>Methods: </strong>This study utilized an umbrella review approach to discern factors associated with neonatal mortality. Five international databases, namely Pub Med, Web of Science, Scopus, CINAHL, and EMBASE, were meticulously searched to achieve this.</p><p><strong>Results: </strong>The initial search yielded 12,631 articles using a search strategy centered on keywords related to factors contributing to neonatal mortality. Ultimately, 95 articles met the criteria incorporated into this study.</p><p><strong>Conclusion: </strong>This study endeavors to identify the primary risk factors contributing to neonatal mortality. The discerned risk factors have been systematically categorized into four groups: maternal factors, neonatal factors, aspects linked to healthcare systems, and socio-economic factors. As such, it is imperative for policymakers to take heed of these identified risk factors and formulate comprehensive strategies encompassing both long-term and short-term initiatives. Effective interventions spanning various sectors are crucial for the prevention of neonatal mortality.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1272-1283"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tracking of Infectious Diseases in Shahr-i Sokhta (Burnt City) during the Bronze Age (ca. 3200-2200 BCE) through Anemic Signs Observed in Excavated Human Skeletons. 通过在出土人类骸骨中观察到的贫血迹象追踪青铜时代(约公元前 3200-2200 年)Shahr-i Sokhta(烧焦的城市)的传染病。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Negar Bizhani, Giorgia Vincenti, Seyyed Mansur Seyyed Sajjadi, Jean Dupouy-Camet, Rouhollah Shirazi, Mehdi Nateghpour, Faranak Kargar, Vahid Shariati, Pier Francesco Fabbri, Gholamreza Mowlavi
{"title":"Tracking of Infectious Diseases in Shahr-i Sokhta (Burnt City) during the Bronze Age (ca. 3200-2200 BCE) through Anemic Signs Observed in Excavated Human Skeletons.","authors":"Negar Bizhani, Giorgia Vincenti, Seyyed Mansur Seyyed Sajjadi, Jean Dupouy-Camet, Rouhollah Shirazi, Mehdi Nateghpour, Faranak Kargar, Vahid Shariati, Pier Francesco Fabbri, Gholamreza Mowlavi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The intriguing area of paleopathology merges the disciplines of archeology and biological studies. Using this line of research, it is possible to identify diseases that have left skeletal traces in the past. In addition, diseases such as various anemia that occur in childhood, when bone tissue is soft and retains evidence, can be identified in ancient bones. Cribra orbitalia (Co<i>)</i>, cribra cranii (Cc<i>)</i>, and porotic hyperostosis (Ph<i>)</i> were ancient skeletal remains' most common degenerative anomalies.</p><p><strong>Methods: </strong>Shahr-i Sokhta dated back to 3200-1800 BCE, is the subject of our research; it is located in Sistan and Baluchistan province (Iran). The research was done on the archaeological data collected during the MAIPS expeditions at Shahr-i Sokhta (2017-2021) kept at the storage of the excavated materials on the site. The skeletal remains were examined for bone abnormalities such as Co, Cc, and Ph. These symptoms were analyzed to obtain traces of anemia-related diseases at this site. Data has been utilized following the Data Collection Codebook.</p><p><strong>Results: </strong>Ninety-six adults were studied while the anemic signs of CC and Co are respectively seen in 27/72 (37.5 %) and 10/57 (17; 5 %), and these samples have been kept for future analysis.</p><p><strong>Conclusion: </strong>Bones may narrate a person's life, their gender and how old they were when they died besides the diseases they had. Some of the skeletons show signs of anemia, Classical paleopathology lets us to re-confirm studying diseases by further targeted sampling using molecular methods.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1416-1426"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Bioinformatics-Based Approach to Discover Novel Biomarkers in Hepatocellular Carcinoma. 基于生物信息学的方法发现肝细胞癌中的新型生物标记物
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Amir Shourideh, Reza Maddah, Bahareh Shateri Amiri, Zarrin Basharat, Marzieh Shadpirouz
{"title":"A Bioinformatics-Based Approach to Discover Novel Biomarkers in Hepatocellular Carcinoma.","authors":"Amir Shourideh, Reza Maddah, Bahareh Shateri Amiri, Zarrin Basharat, Marzieh Shadpirouz","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Liver hepatocellular carcinoma (LIHC) is a common cancer with a poor prognosis and high recurrence rate. We aimed to identify potential biomarkers for LIHC by investigating the involvement of hub genes, microRNAs (miRNAs), transcription factors (TFs), and protein kinases (PKs) in its occurrence.</p><p><strong>Methods: </strong>we conducted a bioinformatics analysis using microarray datasets, the TCGA-LIHC dataset, and text mining to identify differentially expressed genes (DEGs) associated with LIHC. They then performed functional enrichment analysis and gene-disease association analysis. The protein-protein interaction network of the genes was established, and hub genes were identified. The expression levels and survival analysis of these hub genes were evaluated, and their association with miRNAs, TFs, and PKs was assessed.</p><p><strong>Results: </strong>The analysis identified 122 common genes involved in LIHC pathogenesis. Ten hub genes were filtered out, including <i>CDK1, CCNB1, CCNB2, CCNA2, ASPM, NCAPG, BIRC5, RRM2, KIF20A,</i> and <i>CENPF</i>. The expression level of all hub genes was confirmed, and high expression levels of all hub genes were correlated with poor overall survival of LIHC patients.</p><p><strong>Conclusion: </strong>Identifying potential biomarkers for LIHC can aid in the design of targeted treatments and improve the survival of LIHC patients. The findings of this study provide a basis for further research in the field of LIHC and contribute to the understanding of its molecular pathogenesis.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1332-1342"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488550/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eating Behavior, Sleep Disorders and Digital Game Addiction in Children and Determination of Associated Factors by CHAID Analysis. 儿童的饮食行为、睡眠障碍和数字游戏成瘾以及通过 CHAID 分析确定相关因素。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Bedriye Ural, Esin Sezgin, Elvan Yilmaz-Akyuz
{"title":"Eating Behavior, Sleep Disorders and Digital Game Addiction in Children and Determination of Associated Factors by CHAID Analysis.","authors":"Bedriye Ural, Esin Sezgin, Elvan Yilmaz-Akyuz","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Healthy nutrition and good quality sleep are one of the most important factors for growth and development in a child. Digital game addiction may cause some problematic behaviors and affect children's nutrition and sleep. We aimed to investigate the relationship between digital game addiction, eating behavior, and sleep disorders in children.</p><p><strong>Methods: </strong>The study was conducted with 252 mothers with children between the ages of 4-7 years, selected by convenient sampling methods. The Digital Game Addiction Scale, Children's Eating Behavior Questionnaire and The Sleep Disturbance Scale for Children (SDSC) were used to collect data. The correlation coefficient and the decision tree CHAID algorithm were used in the data analysis.</p><p><strong>Results: </strong>Digital game addiction negatively affects children's eating behavior and sleep patterns. It was found that there was a mostly positive but weakly significant relationship between digital game addiction and children's eating behaviors (<i>P</i><.01; <i>P</i><.05) and a highly significant relationship was found between the sleep disorder scale sleep hyperhidrosis sub-dimension (<i>P</i><.05). While digital game addiction is affected by gender, the mother's education level, and eating behavior are affected by the mother's age, the parent's education level, and the child's gender (<i>P</i><.05). The child's age is the variable that affects the children's sleep disorder (<i>P</i><.05).</p><p><strong>Conclusion: </strong>Intervention programs for children and families can be created for the causes of digital game addiction, its effects on child development and the correct use of the digital world.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 6","pages":"1293-1303"},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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