Iranian Journal of Public Health最新文献

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The Impact of Multidisciplinary Educational Team-Based Clinical Nursing Pathway on the Psychological Resilience, Treatment Adherence, Pain Management and Quality of Life in Cancer Patients. 基于多学科教育团队的临床护理路径对癌症患者心理复原力、治疗依从性、疼痛管理和生活质量的影响。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15567
Xue Wang, Hui Wang, Jing He, Xia Li, Yanhong Cang
{"title":"The Impact of Multidisciplinary Educational Team-Based Clinical Nursing Pathway on the Psychological Resilience, Treatment Adherence, Pain Management and Quality of Life in Cancer Patients.","authors":"Xue Wang, Hui Wang, Jing He, Xia Li, Yanhong Cang","doi":"10.18502/ijph.v53i4.15567","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15567","url":null,"abstract":"<p><strong>Background: </strong>We aimed to investigate the impact of multidisciplinary educational team-based clinical nursing pathway on the psychological resilience, treatment adherence, pain management and quality of life in cancer patients.</p><p><strong>Methods: </strong>From 2019 to 2020, eighty two cancer patients were selected and randomly divided into the control group and the observational group. Both groups were treated with routine oncology nursing and the multidisciplinary educational team-based clinical nursing pathway, respectively. Psychological resilience, pain management and qualify of life were assessed by the Chinese version of the Connor-Davidson resilience scale, revised American Pain Society Patient Outcome Questionnaire and the Nottingham health profile, respectively. Treatment adherence was semi-quantitatively classified as \"good\", \"fair\" and \"bad\".</p><p><strong>Results: </strong>Patient's psychological resilience, compliance, pain outcome and quality of life were similar between the control group and the observational group on admission. Patient's psychological resilience, compliance and pain outcome in the observational group were significantly superior to those in the control group one day prior to discharge and 2 months post-discharge (all <i>P</i><0.05). The scores of energy, emotions, sleep and mobility were significantly different between the observational group and the control group one day prior to discharge and 2 months post-discharge (all <i>P</i><0.05). Significant improvements were observed with regard to the scores of energy, sleep and mobility in the control group 2 months post-discharge, whereas the scores of energy, emotions, sleep and mobility improved dramatically in the observational group (all <i>P</i><0.05).</p><p><strong>Conclusion: </strong>Compared with routine oncology nursing, multidisciplinary educational team-based clinical nursing pathway could improve patient's psychological resilience, treatment adherence, pain management and quality of life.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Middle-Aged Women's Demographics, Health Behavior, And Health Status on Health-Related Quality of Life by Economic Activity Participation: Panel Evidence from Korea. 中年妇女的人口统计、健康行为和健康状况对参与经济活动的健康相关生活质量的影响:来自韩国的面板证据。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15557
Min-Jeong Park, Hwee Wee
{"title":"Effects of Middle-Aged Women's Demographics, Health Behavior, And Health Status on Health-Related Quality of Life by Economic Activity Participation: Panel Evidence from Korea.","authors":"Min-Jeong Park, Hwee Wee","doi":"10.18502/ijph.v53i4.15557","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15557","url":null,"abstract":"<p><strong>Background: </strong>Middle-aged women have lower health-related quality of life (HRQoL) than men, and women's participation in economic activities is an important issue. In this study, the middle-aged female population was classified by economic activity participation to explore HRQoL and to identify related factors.</p><p><strong>Methods: </strong>We obtained data from the 2017 Korea Health Panel Survey (<i>N</i> = 1857 women aged 50-64 years), analyzed with chi-squared tests, <i>t</i>-tests, analyses of variance, and multiple regression analyses. HRQoL was measured with the Euro QoL-5 Dimensions index, and four demographic factors, four health behavior factors, and ten health status factors were entered.</p><p><strong>Results: </strong>HRQoL was lower in the economically inactive group compared to the active group. Education, physical activity, chronic disease, vision problem, dental problem, activity restriction, frustration, and anxiety were associated with HRQoL in both groups. Spouse and household income were additional predictors identified only in the economically inactive group, and the 10 factors explained 36.0% of the variance. In the economically active group, drinking, sleeping time, hearing problem, stress, and depression were additional predictors identified, and the 13 factors explained 23.0% of the variance.</p><p><strong>Conclusion: </strong>Healthcare providers should consider both common predictors between economically active and inactive middle-aged women as well as predictors that were unique to each group to improve their HRQoL.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphological Changes in Adolescent Athletes with Chronic Ankle Instability. 患有慢性踝关节不稳的青少年运动员的形态变化
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15574
Sang-Hyup Song, Namwoong Kim, Jupil Ko
{"title":"Morphological Changes in Adolescent Athletes with Chronic Ankle Instability.","authors":"Sang-Hyup Song, Namwoong Kim, Jupil Ko","doi":"10.18502/ijph.v53i4.15574","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15574","url":null,"abstract":"","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in Melanoma Mortality in Serbia: A 22-Year Population-Based Study. 塞尔维亚黑色素瘤死亡率趋势:一项为期 22 年的人口研究。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15559
Zorana Babic, Nemanja Rancic, Sanja Ilic, Snezana Corovic, Vesna Milicic, Gordana Djordjevic, Ognjen Djordjevic, Sladjana Ilic, Svetlana Radevic
{"title":"Trends in Melanoma Mortality in Serbia: A 22-Year Population-Based Study.","authors":"Zorana Babic, Nemanja Rancic, Sanja Ilic, Snezana Corovic, Vesna Milicic, Gordana Djordjevic, Ognjen Djordjevic, Sladjana Ilic, Svetlana Radevic","doi":"10.18502/ijph.v53i4.15559","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15559","url":null,"abstract":"<p><strong>Background: </strong>We aimed to investigating the sex-specific and age-specific melanoma mortality trends observed on the territory of Serbia between 2000 and 2021.</p><p><strong>Methods: </strong>This population-based study used data from the Statistical Office of the Republic of Serbia database during the period 2000-2021. The calculation of the gender and age-standardized rates (ASR) was performed. We used a regression analysis complete with linear trend model.</p><p><strong>Results: </strong>The mean ASR was 1.77 per 100,000 people, meaning that male mortality rates (2.24 per 100,000) was higher than female mortality rates (1.34 per 100,000). During the observation period, a rising trend in mortality from melanoma skin cancer was reported. Observed by gender, the change of melanoma mortality trend was significant in men (<i>P</i>=0.021), but not in women (<i>P</i>=0.747). The annual growth rate of ASRs values was 1.43%. A increase in the melanoma mortality rate was observed since 2000 by 2.44% annually in males and by 2.79% annually in females. Mortality rates were increasing in both sexes as they aged, and the greatest number of deaths was recorded in the group of those aged 80 yr or above (16.25 per 100,000 for men; 10.45 per 100,000 for women).</p><p><strong>Conclusion: </strong>Our study findings underline the importance of launching more effective public health awareness campaigns to educate people about the dangers of melanoma and its symptoms' detection along with establishing a diagnosis at an early stage of the disease, especially among male patients and those at an advanced age.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brisk Walking Exercise Has Benefits of Lowering Blood Pressure in Hypertension Sufferers: A Systematic Review and Meta-Analysis. 快步走运动有益于降低高血压患者的血压:系统回顾与元分析》。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15554
Rehmaita Malem, Ristiani Ristiani, Muhibbullah Ali Puteh
{"title":"Brisk Walking Exercise Has Benefits of Lowering Blood Pressure in Hypertension Sufferers: A Systematic Review and Meta-Analysis.","authors":"Rehmaita Malem, Ristiani Ristiani, Muhibbullah Ali Puteh","doi":"10.18502/ijph.v53i4.15554","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15554","url":null,"abstract":"<p><strong>Background: </strong>Brisk walking exercise is an aerobic exercise with the moderate intensity that can reduce the risk in people with hypertension. This systematic review and meta-analysis aimed to investigate the effects of interventions related to brisk walking and blood pressure reduction in hypertensive patients.</p><p><strong>Methods: </strong>Search strategy through the PubMed, Science Direct, ProQuest, and Google Scholar databases limited from 2018 to 2023. The components measured are systolic blood pressure and diastolic blood pressure. This study uses the Black and Downs checklist to measure the quality of the study, which consists of 3, namely high quality, medium quality, and low quality. Effect size analysis of the study used the standard mean difference between brisk walking exercise and not doing brisk walking exercise.</p><p><strong>Results: </strong>The results of the identification of the database obtained 1700 articles, then limited by title, year, abstract (n = 381), and full-text article feasibility (n = 76) to obtain nine articles included. Nine articles were included in the systematic review and meta-analysis by study quality: six studies of high quality, 2 of medium quality, and 1 of low quality. Systolic blood pressure had a substantial effect size in all studies (<i>P</i><0.05; SMD: -0.55) while diastolic blood pressure had an effect medium size (<i>P</i>=0.05; SMD: 0.13).</p><p><strong>Conclusion: </strong>Brisk walking exercise can significantly reduce blood pressure in people with hypertension-recommendations for the future to carry out community-based physical activity in improving physical health, including heart health.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design and Framework for Developing Disaster Health Information System (DHIS): A Systematic Review. 开发灾害卫生信息系统(DHIS)的设计与框架:系统回顾。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15552
Arief Tarmansyah Iman, Hari Kusnanto Josef, Ariani Arista Putri Pertiwi, Lutfan Lazuardi, Lia Nurcahyani, Faizul Hasan
{"title":"Design and Framework for Developing Disaster Health Information System (DHIS): A Systematic Review.","authors":"Arief Tarmansyah Iman, Hari Kusnanto Josef, Ariani Arista Putri Pertiwi, Lutfan Lazuardi, Lia Nurcahyani, Faizul Hasan","doi":"10.18502/ijph.v53i4.15552","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15552","url":null,"abstract":"<p><strong>Background: </strong>Health information systems are critically important in disaster management. It supports disaster management activities and the information needed for decision-making support. We aimed to evaluate comprehensively published literature on disaster health information systems designed to identify and extract the required framework and components.</p><p><strong>Methods: </strong>A systematic review approach was used to systematically seek, screen, and synthesize data extracted from papers on using health information systems in disasters from the electronic databases (Scopus, PubMed, ProQuest, and SAGE) with no limit up to Jan 2022 following the PRISMA declaration for reporting. The inclusion criteria consisted of full-text journal articles, publications in English, and studies focusing on disaster health information systems, critically evaluated articles using the Joanna Brigg Institute (JBI). Content analysis was used to analyze extracted data.</p><p><strong>Results: </strong>Of 998 identified references, 18 articles were finally included and analyzed in this study and they are good quality according to appraisal results using JBI. Most reports described research of development or working prototypes and working framework; only two referred to early research or proposed design or framework. Of 18 articles; identified into 3 themes; 4 DHISs in pre-disaster, thirteen DHISs used during the disaster, and one DHIS in post-disaster were identified.</p><p><strong>Conclusion: </strong>All the systems have a design or framework starting from strategies and plans, information flow, disaster management, and operation engagement, and involve all stakeholders, including the community. Its systems are supported by the latest technology and methods and the principles of integration and interoperability to obtain a DHIS that can assist decision-making processes.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Psychological Intervention Based on the Self-Transcendence Theory on the Sleep Quality of Chinese Nurses. 基于自我超越理论的心理干预对中国护士睡眠质量的影响
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15558
Wei Guofang, Wei Zhang, Zhen Zhu
{"title":"Effects of Psychological Intervention Based on the Self-Transcendence Theory on the Sleep Quality of Chinese Nurses.","authors":"Wei Guofang, Wei Zhang, Zhen Zhu","doi":"10.18502/ijph.v53i4.15558","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15558","url":null,"abstract":"<p><strong>Background: </strong>COVID-19 infection is transmitted easily and quickly, exposing medical care workers, especially nursing workers, to tremendous stress. Therefore, identifying the factors influencing the sleep quality of nurses and implementing corresponding interventions are conducive to improving the sleep quality of nurses and enhancing their nursing quality.</p><p><strong>Methods: </strong>Form September to December 2022, a survey-based evaluation was conducted on 1074 front-line clinical nurses randomly selected from three hospitals in Zhejiang Province, China. Based on the survey results, 152 nurses were selected and randomly divided into the experimental group and the control group, with 76 nurses in each group. A 2-month psychological intervention based on the self-transcendence theory was conducted, and the two groups were compared before and after the intervention.</p><p><strong>Results: </strong>The average PSQI score of nurses was 7.19±3.65, with 471 of them suffering from poor sleep (PSQI>7), accounting for 45.46%. In addition, 57.10% of the nurses were under excessive stress, whereas 62% of them had a Self-Rating Anxiety Scale score of ≥50. After the intervention, the PSQI score of the experimental group was significantly lower than that of the control group, with the difference being statistically significant (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Clinical nurses in tertiary hospitals have poor sleep quality and more severe stress and anxiety problems during COVID-19 than during non-epidemic periods. Clinical interventions based on the self-transcendence theory can effectively improve the sleep quality of nurses. Results of this study provide reference for enhancing the sleep quality of nurses and ensuring their physical and mental health during epidemic.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors and Outcomes Associated with Maternal Obesity and Overweight: A Cross Sectional Study among Moroccan Women in Marrakech. 与产妇肥胖和超重有关的风险因素和结果:马拉喀什摩洛哥妇女横断面研究》。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15561
Sara Samim, Mohamed Loukid, Saloua Lamtali
{"title":"Risk Factors and Outcomes Associated with Maternal Obesity and Overweight: A Cross Sectional Study among Moroccan Women in Marrakech.","authors":"Sara Samim, Mohamed Loukid, Saloua Lamtali","doi":"10.18502/ijph.v53i4.15561","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15561","url":null,"abstract":"<p><strong>Background: </strong>Obesity is becoming a real challenge for public health among pregnant women. This study aimed to identify sociodemographic and lifestyle risk factors and outcomes linked to maternal obesity and overweight.</p><p><strong>Methods: </strong>A cross-sectional study was carried out from Nov 2021 to Dec 2022 in the maternity health facility of Mohammed VI Hospital, as well as in one of the main health centers with a delivery unit in Marrakech, Morocco. Parturients were divided into four categories according to their pre pregnancy BMI: underweight, normal weight, overweight and obese. We used the chi-square test (χ<sup>2</sup>) to analyze the sociodemographic and lifestyle factors associated with maternal obesity and overweight. The same tool was utilized to explore maternal and neonatal complications.</p><p><strong>Results: </strong>Overall, 400 parturient women with singleton pregnancies were included in the study. The prevalence of overweight and obesity was 29.8% and 31.5% respectively. Maternal age, type of housing, practicing sports, feelings about pregnancy were correlated with an increased risk of maternal obesity and being overweight. The risks of gestational diabetes, hypertension, anemia, cesarean delivery, and fetal macrosomia were higher among overweight and obese women compared to normal weight ones. The differences were significant (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Maternal overweight and obesity are strongly linked with socio-economic, lifestyle, and psychological factors which can lead to serious complications for both mother and baby. Further research is needed to develop appropriate preventive measures and interventions for maternal obesity and overweight.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role and Function of Secretory Protein Matrix Metalloproteinase-3 (MMP3) in Cervical Cancer. 分泌蛋白基质金属蛋白酶-3(MMP3)在宫颈癌中的作用和功能
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15562
Lei Shao, Wanqiu Liu, Chunyan Zhang, Wei Ma, Xiao Yu, Jing Han, Xiaojuan Wang
{"title":"The Role and Function of Secretory Protein Matrix Metalloproteinase-3 (<i>MMP3</i>) in Cervical Cancer.","authors":"Lei Shao, Wanqiu Liu, Chunyan Zhang, Wei Ma, Xiao Yu, Jing Han, Xiaojuan Wang","doi":"10.18502/ijph.v53i4.15562","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15562","url":null,"abstract":"<p><strong>Background: </strong>We started with RNA-seq analysis and aimed to investigate the possibility of secretory protein matrix metalloproteinase-3(<i>MMP3</i>) as a new diagnosis and therapeutic target in cervical cancer.</p><p><strong>Methods: </strong>The study was conducted on Nov 2021 at the Second Affiliated Hospital of Qiqihar Medical University, Qiqihar, China. Through conjoint analysis of gene expression data as well as survival rate data, we explored the potential secretary proteins associated with cervical cancer carcinogenesis. One hundred patients aged 38-72 years with clinical stage I-IV cervical cancer, and 100 age-matched healthy women were included. The expression changes in serum of clinical patients was detected. We knockdown or overexpressed the secretory proteins then explored its influence on biological function of cervical cancer cells.</p><p><strong>Results: </strong>By cross-analysis of The Cancer Genome Atlas (TCGA) database and MetazSecKB database, <i>MMP3</i> gene was most significantly upregulated in cervical cancer patients (<i>P</i> < 0.05). Furthermore, <i>MMP3</i> protein was remarkably increased in the serum of clinical cervical cancer patients and decreased after receiving treatment. Overexpression of <i>MMP3</i> in HT-3 cells or culturing new cells using the supernatant of the medium after <i>MMP3</i> overexpression could increase cell viability (<i>P</i> < 0.05) as well as proliferation (<i>P</i> < 0.05). Knockdown of <i>MMP3</i> reduced the phosphorylation of PI3K as well as AKT proteins, while the PI3K phosphorylation inhibitors could suppress the impact of <i>MMP3</i> on increasing cell proliferation as well as viability.</p><p><strong>Conclusion: </strong><i>MMP3</i> could be an underlying target for early diagnosis and treat cervical cancer in the future.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Shaping Exercise Patterns and Health Status among the Elderly in Aging Nations: A South Korean Perspective. 影响老龄化国家老年人运动模式和健康状况的因素:韩国的视角。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15566
Eun Surk Yi, Mehdi Rezaei, Hyun Byun, Sangwan Jeon
{"title":"Factors Shaping Exercise Patterns and Health Status among the Elderly in Aging Nations: A South Korean Perspective.","authors":"Eun Surk Yi, Mehdi Rezaei, Hyun Byun, Sangwan Jeon","doi":"10.18502/ijph.v53i4.15566","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15566","url":null,"abstract":"<p><strong>Background: </strong>The global phenomenon of population aging requires an understanding of the factors influencing the health of the elderly becomes imperative. We aimed to focus on South Korea, a nation set to become an aging society by 2025. The study examined the influence of regular exercise and exercise types on the health of the elderly with particular attention to South Korea's unique sociodemographic context.</p><p><strong>Methods: </strong>We targeted individuals aged 50 yr and above. The study was conducted through online surveys from August to September 2023. Utilizing Logistic Regression analysis and Chi-Square tests, the research explored correlations, trends, and influencing factors affecting elderly exercise behaviors, encompassing demographic variables, health status, and exercise types.</p><p><strong>Results: </strong>The analysis of demographic characteristics revealed that marital status, education level, and financial status displayed diverse representations within the sample. Comparisons between health status and exercise groups suggested potential health benefits for the Regular Exercise group. Logistic Regression analysis identified significant influences of gender and financial status on regular exercise engagement. Additionally, a strong relationship between health status and exercise preferences, notably strength training, emerged.</p><p><strong>Conclusion: </strong>Regular exercise and exercise types benefit elderly individuals. Men and those with better financial status are more likely to exercise regularly. Strength training emerges as a significant contributor to better health across various health status categories. Policymakers and healthcare professionals should consider these insights to develop targeted interventions for promoting healthy aging, acknowledging the cultural and socioeconomic factors of South Korea's aging population.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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