{"title":"RNA Sequencing Data Analysis of Oligoasthenoteratozoospermia Patients' Sperms and Effects of Curcumin on the Expression of Some Genes during Sperm Cryopreservation and Freeze-Thawing Process.","authors":"Farnoosh Naseri, Elham Siasy, Seyed Abdolhamid Angaji, Maryam Peyvandi","doi":"10.18502/ijph.v54i1.17593","DOIUrl":"10.18502/ijph.v54i1.17593","url":null,"abstract":"<p><strong>Background: </strong>The cause of oligoasthenoteratozoospermia (OAT) is unclear. In this original study, we examined OAT patients' sperm using RNA-sequencing and studied the impact of curcumin on gene expression during sperm cryopreservation and freeze-thawing.</p><p><strong>Methods: </strong>RNA-seq was performed using the Galaxy Europe server in IKHC (Imam Khomeini Hospital Complex), Tehran, Iran in 2023. Sperm samples were collected from 30 OAT patients and 30 healthy volunteers. Sperm parameters were analyzed, and samples were frozen with 20 μM curcumin at -196 °C for one week. Thawed samples were assessed for sperm parameters, and the expression levels of <i>bax</i>, <i>bak</i>, <i>bcl-2</i>, <i>bclw</i>, <i>casp9</i>, <i>apaf-1</i>, <i>SOD</i>, <i>cat</i>, and <i>GPX4</i> genes were measured using RT-PCR.</p><p><strong>Result: </strong>RNA-seq analysis showed increased expression of <i>NANOS1</i>, <i>HSPA6</i>, and <i>ALOXE3</i> genes, while <i>BHLHE41</i>, <i>Hey1</i>, and <i>PPM1D</i> genes were down-regulated in OAT patients' sperm. Curcumin (20 μM) effectively preserves sperm parameters and motility during cryopreservation in healthy subjects and in OAT patients in particular. Cryopreserved sperm from both OAT patients and healthy individuals exhibited reduced expression of pro-apoptotic genes, increased expression of anti-apoptotic genes, and elevated levels of <i>SOD</i> and <i>GPX4</i> genes.</p><p><strong>Conclusion: </strong>Altered expressions of <i>NANOS1</i>, <i>HSPA6</i>, <i>ALOXE3</i>, <i>BHLHE41</i>, <i>Hey1</i>, and <i>PPM1D</i> genes likely contribute to OAT development. Additionally, curcumin protects sperm parameters during cryopreservation for both healthy individuals and OAT patients.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"214-224"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deep Learning-Based Body Shape Clustering Analysis Using 3D Body Scanner: Application of Transformer Algorithm.","authors":"Minsoo Jeon, Jiwun Yoon, Hyo Jun Yun","doi":"10.18502/ijph.v54i1.17583","DOIUrl":"10.18502/ijph.v54i1.17583","url":null,"abstract":"<p><strong>Background: </strong>This study was conducted to perform deep learning-based body shape cluster analysis using 3D Body Scanner.</p><p><strong>Methods: </strong>For this study, 54 variables were measured using 3D Body Scanner on 366 adult men and women at Korea National Sport University in 2022. Transformer learning and dimensionality reduction models were used to perform cluster analysis on the measured data. Mann-Whitney test and Kruskal-Wallis test were applied to compare the principal component differences of new scale characteristics, and all statistical significance levels were set at .05.</p><p><strong>Results: </strong>First, among the two methods for classifying body types, the transformer algorithm had a higher performance in body type classification. Second, in the classification of body type clusters, two clusters, endomorphic body type and ectomorphic body type, were divided into six clusters, two for cluster 1 and four for cluster 2.</p><p><strong>Conclusion: </strong>The six clusters provide more granular information than previous body type classifications, and we believe that they can be used as basic information for predicting health and disease.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"133-143"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nur Isnaini, Fatwasari Tetra Dewi, Ema Madyaningrum, Uki Noviana
{"title":"Family-Centered Education for Older Adults with Hypertension: A Scoping Review.","authors":"Nur Isnaini, Fatwasari Tetra Dewi, Ema Madyaningrum, Uki Noviana","doi":"10.18502/ijph.v54i1.17573","DOIUrl":"10.18502/ijph.v54i1.17573","url":null,"abstract":"<p><strong>Background: </strong>Older adults are the most hypertensive population compared to other age groups. The purpose of this study was to determine an education model involving the family and the outcomes of the program.</p><p><strong>Methods: </strong>Studies conducted in 2023. The search terms \"Aged or Older Adult or Elderly and Family-centered or Family Nursing and Hypertension or High Blood Pressure\" were used to conduct a scoping review in the journals PROQUEST, SCOPUS, MEDLINE, COCHRANE, and PubMed until 2022. The flowchart for the PRISMA Scoping review shows the search and selection procedure. Tools from the Joanna Briggs Institute (JBI) for Randomized Controlled Trials and Quasi-Experimental Studies are used to critically evaluate a few chosen papers.</p><p><strong>Results: </strong>There were 11 articles found out of 2,355 articles in the search results. To increase perceived threat, self-efficacy, and self-confidence, the family-involved education intervention is implemented in phases. Knowledge, family involvement, blood pressure, cholesterol, uric acid, quality of life, and behavioral changes were among the outcomes that were evaluated.</p><p><strong>Conclusion: </strong>Education involving families of the elderly with hypertension can affect a decrease in blood pressure, an increase in self-efficacy and good behavioral change, an increase in self-esteem, improved life quality, and family empowerment.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"36-47"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Strength-Based Narrative Therapy on Depression Symptoms and Quality of Life in the Elderly.","authors":"Shengguo Zhu, Qiaoyuan Liao, Huaping Yuan","doi":"10.18502/ijph.v54i1.17582","DOIUrl":"10.18502/ijph.v54i1.17582","url":null,"abstract":"<p><strong>Background: </strong>Depression is a common psychological problem among the elderly. It undermines the elderly's quality of life and imposes a heavy economic burden on society and families. Depression in this group must be addressed, but effective intervention therapies remain absent in existing studies. Strength-based cognitive behavior theory was combined with narrative therapy in this study. Its effect on depression in the elderly was verified through an intervention experiment.</p><p><strong>Methods: </strong>From April to June 2024, 319 elderly people were recruited from Huoju Community in Changsha, Hunan Province, China to examine the factors influencing depression. A total of 85 of them with depression symptoms were included in a randomized intervention experiment and divided into two groups: 42 in the experiment group and 43 in the control group. The experiment group was intervened with strength-based narrative therapy, whereas the control group was given no targeted intervention.</p><p><strong>Results: </strong>After the intervention, 1) the total depression score of the experiment group was significantly lower than that of the control group (<i>P</i>=0.001); 2) the mental state score of the control group decreased more significantly than that of the experiment group (<i>P</i><0.05); and 3) the quality-of-life score of the experiment group was significantly higher than that of the control group at different time points (<i>P</i><0.05).</p><p><strong>Conclusion: </strong>Strength-based narrative therapy can effectively alleviate depression symptoms in the elderly, improve their mental state, delay their cognitive decline, and enhance their quality of life. It is an effective option to promote the elderly's mental health.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"124-132"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Telemedicine-Based Intervention on Breastfeeding Self-Efficacy in Iranian Women: A Systematic Review and Meta-Analysis.","authors":"Zahra Hadizadeh-Talasaz, Sedigheh Abdollahpour","doi":"10.18502/ijph.v54i1.17571","DOIUrl":"10.18502/ijph.v54i1.17571","url":null,"abstract":"<p><strong>Background: </strong>Breastfeeding self-efficacy (BSE) is a modifiable factor that can enhance breastfeeding rates. Telemedicine constitutes safe and low-cost health services that can be developed for the interaction between professionals and clients. Therefore, this study aimed to review the effectiveness of telemedicine-based intervention on BSE in Iranian women.</p><p><strong>Methods: </strong>This systematic and meta-analysis review was performed according to PRISMA guidelines. English databases including Web of Science, PubMed, Scopus, and Persian databases including SID, Magiran, and IranMedex was searched until Aug 1, 2023 to identify randomized control trials about telemedicine-based interventions on BSE in Iran. The search strategy was focused on terms and eligibility criteria. Data analysis was done using CMA V.2 software. The risk of bias in the included studies was assessed.</p><p><strong>Results: </strong>Out of 385 articles, eight articles that met the inclusion criteria were included in the meta-analysis. The overall result demonstrated that telemedicine-based interventions have a positive impact on BSE compared with the control, especially in the long-term intervention (pooled SMD= 1.27; 95% CI= 1.01-1.53, <i>P-</i>value<0/001); heterogeneity (Cochrane's Q-value=51.94, <i>P</i><0/001, I2=76.90%). In addition, twelve weeks of postpartum had more effect on BSE than the others. Also, breastfeeding intervention in the postpartum period was more effective compared with pregnancy. The publication bias among included studies was assessed by funnel plot.</p><p><strong>Conclusion: </strong>This review could give insight to healthcare providers into the effect of telemedicine on BSE. Therefore, by strengthening BSE through telemedicine interventions, especially for women who do not have the conditions for face-to-face counseling, we can expect positive results.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"13-23"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787846/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Faniea Maawati, Dwi Indah Iswanti, I Made Moh Yanuar Saifudin, Blacius Dedi
{"title":"Nurses' Perception towards Electronic Medical Records System: An Integrative Review of Barriers and Facilitators.","authors":"Faniea Maawati, Dwi Indah Iswanti, I Made Moh Yanuar Saifudin, Blacius Dedi","doi":"10.18502/ijph.v54i1.17575","DOIUrl":"10.18502/ijph.v54i1.17575","url":null,"abstract":"<p><strong>Background: </strong>Electronic medical records (EMRs) can minimize mistakes, enhance the comprehensiveness, legibility, and overall comprehension of medical records. However, nurses' limited familiarity with advanced technology lowers their confidence in utilizing EMRs. We aimed to collect and synthesize the most credible evidence on nurses' perception of EMRs, along with the barriers and facilitators that influence their acceptance.</p><p><strong>Methods: </strong>Searching for relevant studies was carried out across three electronic databases, namely PubMed, Scopus and ProQuest in Dec 2023. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was followed in this study report. The selected studies were then analyzed narratively and organized thematically for presentation.</p><p><strong>Results: </strong>Out of the 4,382 articles identified through comprehensive database searches, only 19 met the criteria for inclusion and reviewed. Through the synthesis of findings, two primary themes emerged, including nurses' perceptions and experiences with EMRs and facilitators & barriers for nurses' in utilizing EMRs.</p><p><strong>Conclusion: </strong>Nurses' perspectives are shaped by their computer skills, confidence in their abilities, and training. Despite obstacles such as nurse stress, EMRs present advantages such as enhanced patient care and decreased errors. Augmenting computer competency, delivering training, and guaranteeing support are essential for effective EMRs integration, leading to enhanced healthcare provision and better patient results.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"62-73"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787828/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Breathing Yoga Practice on Resting Vital Capacity in Elderly Women with Intellectual Disability.","authors":"Na-Hyun Kim","doi":"10.18502/ijph.v54i1.17596","DOIUrl":"10.18502/ijph.v54i1.17596","url":null,"abstract":"","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"229-230"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Binu Joseph, Varghese K Joseph, Santhosh Kareepadath Rajan
{"title":"Effectiveness of Couple Interventions in Marital Distress: A Systematic Review and Meta-Analysis.","authors":"Binu Joseph, Varghese K Joseph, Santhosh Kareepadath Rajan","doi":"10.18502/ijph.v54i1.17581","DOIUrl":"10.18502/ijph.v54i1.17581","url":null,"abstract":"<p><strong>Background: </strong>Couple interventions focus on resolving relationship issues and improving partners' intimacy. Several intervention models are used on different occasions to deal with the issues. The present systematic review and meta-analysis investigated the effectiveness of such couple interventions dealing with marital distress.</p><p><strong>Methods: </strong>Using the PRISMA guidelines for reporting systematic reviews and meta-analyses, a search was carried out to identify published articles in the areas of study. The meta-analysis investigated the effectiveness of couple interventions by comparing the post-intervention assessments of the experimental and control groups.</p><p><strong>Results: </strong>The systematic review helped to identify twelve empirical studies published within the last ten years in the following databases: ScienceDirect, EBSCO, APA PsycINFO, NCBI, ProQuest, and Google Scholar. Meta-analysis showed a statistically significant overall effect size (Cohen's <i>d</i> = 0.85, 95% CI: 0.56 - 1.14). Cochran's <i>Q</i> showed that there was a substantial difference between the studies. There were signs of publication bias.</p><p><strong>Conclusion: </strong>The current study revealed an overall large effect size, indicating that different couple interventions had a noticeable impact on distressed couples who received interventions as opposed to couples who did not receive any interventions.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"112-123"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emina Popovic, Jasmina Stojanovic, Snezana Radovanovic, Strahinja Krsmanovic, Mila Veselinovic, Emilija Zivkovic Marinkov, Milos Stepovic, Marija Radovanovic, Jovana Radovanovic
{"title":"Quality of Life of Families of Children with Speech Disorders.","authors":"Emina Popovic, Jasmina Stojanovic, Snezana Radovanovic, Strahinja Krsmanovic, Mila Veselinovic, Emilija Zivkovic Marinkov, Milos Stepovic, Marija Radovanovic, Jovana Radovanovic","doi":"10.18502/ijph.v54i1.17584","DOIUrl":"10.18502/ijph.v54i1.17584","url":null,"abstract":"<p><strong>Background: </strong>Under the influence of numerous life factors, speech constantly undergoes changes. Parents of children with speech and language disorders have a lower quality of life compared to the parents of children without. The study examined different domains of the quality of life of families with and without speech disorders.</p><p><strong>Methods: </strong>A cross-sectional study was conducted in Serbia, in 2024, on a sample of 206 preschool children aged 5-7 years and their parents/guardians. As a research instrument, in addition to the General Questionnaire on sociodemographic characteristics of children and parents' respondents/guardians, the Family Quality of Life Survey (FQOL) was used to assess the family's quality of life.</p><p><strong>Results: </strong>Articulation disorder was detected in 78.2% of children. Difference between the two groups of parents was found in terms of place of residence, work status, education levels, and children's age. From the five domains of family quality of life, significance was found in the domain of family interaction regarding the support, support related to disability, and family safety. Regarding the physical/material well-being domain, the significance was found for dental care and parenting domains. No differences were found in the domain of emotional well-being.</p><p><strong>Conclusion: </strong>The importance of the study reflects in the possibility of applying the obtained research results for the creation of educational programs that will encourage positive attitudes of parents and children about speech therapy interventions, which can influence successful rehabilitation of speech disorders and improve family quality of life.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"144-154"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787845/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Scoping Review of 20 Years Breast Cancer Screening Programs in Iran.","authors":"Pouran Raeissi Dehkordi, Zeinab Dolatshahi, Hassan Abolghasem Gorji, Seyed Massoud Hashemi, Nahid Reisi, Toraj Harati Khalilabad","doi":"10.18502/ijph.v54i1.17577","DOIUrl":"10.18502/ijph.v54i1.17577","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer (BC) is the leading cancer among women globally. Early detection through screening is vital for reducing mortality, complementing advancements in treatment.</p><p><strong>Methods: </strong>We aimed to overview BC screening practices in Iran over two-decades to inform policymakers for future research directions and prompt timely diagnoses. A scoping review was conducted on BC studies in Iran from 2000 to 2023, following PRISMA guidelines.</p><p><strong>Results: </strong>We analyzed 129 articles on BC in Iranian women, and finding six main areas.</p><p><strong>Conclusion: </strong>Iran's health system lacks an organized BC screening initiative, facing challenges like inadequate infrastructure, sociocultural barriers, unintegrated health insurance packages, and limited research on key indicators.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 1","pages":"88-100"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}