Effect of Treatment of Hypokinetic Dysarthria in Parkinson's Disease with Speech and Language Therapy: A Meta-Analysis.

IF 1.3 4区医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Iranian Journal of Public Health Pub Date : 2025-06-01 DOI:10.18502/ijph.v54i6.18890

Liang Zhang

{"title":"Effect of Treatment of Hypokinetic Dysarthria in Parkinson's Disease with Speech and Language Therapy: A Meta-Analysis.","authors":"Liang Zhang","doi":"10.18502/ijph.v54i6.18890","DOIUrl":null,"url":null,"abstract":"Background: A meta-analysis study was conducted to measure how to forecast the effect of treatment of hypokinetic dysarthria in Parkinson's-disease with speech and language therapy.Methods: Until October 2024, a comprehensive literature research was conducted, and 1665 related studies were reviewed. The 14 selected studies encompassed 948 participants with hypokinetic dysarthria in Parkinson's disease. The odds ratio (OR) mean difference (MD) and 95% confidence intervals (CIs) were used to look at the outcome of treatment of hypokinetic dysarthria in Parkinson's disease with speech and language therapy using dichotomous or continuous methods with a fixed- or random-effects model.Results: In individuals with hypokinetic dysarthria in Parkinson-disease, speech and language therapy had significantly higher sound pressure level, phonation (MD, 7. 51; 95% CI, 3. 81-11. 20, p<0. 001), reading (MD, 8. 83; 95% CI, 4. 96-12. 69, p<0. 001), monologue (MD, 4. 28; 95% CI, 2. 47-6. 10, p<0. 001), and picture description (MD, 3. 64; 95% CI, 1. 78-5. 50, p<0. 001), and lower Voice Handicap Index (MD, -5. 61; 95% CI, -9. 05- -2. 17, p=0. 001) compared to control treatment.Conclusion: In individuals with hypokinetic dysarthria in Parkinson's disease, speech and language therapy had significantly higher sound pressure level, phonation, reading, monologue, and picture description, and lower Voice Handicap Index compared to control treatment. To validate these finding more studies are required, caution is needed when interpreting these results, since many comparisons had a limited number of selected studies.","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"54 6","pages":"1118-1131"},"PeriodicalIF":1.3000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12241742/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Iranian Journal of Public Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.18502/ijph.v54i6.18890","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}

引用次数: 0

Abstract

Background: A meta-analysis study was conducted to measure how to forecast the effect of treatment of hypokinetic dysarthria in Parkinson's-disease with speech and language therapy.

Methods: Until October 2024, a comprehensive literature research was conducted, and 1665 related studies were reviewed. The 14 selected studies encompassed 948 participants with hypokinetic dysarthria in Parkinson's disease. The odds ratio (OR) mean difference (MD) and 95% confidence intervals (CIs) were used to look at the outcome of treatment of hypokinetic dysarthria in Parkinson's disease with speech and language therapy using dichotomous or continuous methods with a fixed- or random-effects model.

Results: In individuals with hypokinetic dysarthria in Parkinson-disease, speech and language therapy had significantly higher sound pressure level, phonation (MD, 7. 51; 95% CI, 3. 81-11. 20, p<0. 001), reading (MD, 8. 83; 95% CI, 4. 96-12. 69, p<0. 001), monologue (MD, 4. 28; 95% CI, 2. 47-6. 10, p<0. 001), and picture description (MD, 3. 64; 95% CI, 1. 78-5. 50, p<0. 001), and lower Voice Handicap Index (MD, -5. 61; 95% CI, -9. 05- -2. 17, p=0. 001) compared to control treatment.

Conclusion: In individuals with hypokinetic dysarthria in Parkinson's disease, speech and language therapy had significantly higher sound pressure level, phonation, reading, monologue, and picture description, and lower Voice Handicap Index compared to control treatment. To validate these finding more studies are required, caution is needed when interpreting these results, since many comparisons had a limited number of selected studies.

查看原文本刊更多论文

言语和语言疗法治疗帕金森病低运动构音障碍的效果：一项荟萃分析。

背景：我们进行了一项荟萃分析研究，以衡量如何预测言语和语言疗法治疗帕金森病低运动构音障碍的效果。方法：截至2024年10月，全面开展文献调查，查阅相关文献1665篇。入选的14项研究包括948名帕金森病的构音障碍患者。采用比值比（OR）均值差（MD）和95%置信区间（CIs），采用二分类或连续方法，固定或随机效应模型，观察言语和语言治疗帕金森病低动构音障碍的疗效。结果：帕金森病低动构音障碍患者，言语和语言治疗显著提高了声压级、发声（MD, 7）。51;95% ci, 3。81 - 11。20、结论：与对照治疗相比，言语和语言治疗在帕金森病低运动构音障碍患者的声压级、发音、阅读、独白和图片描述方面显著提高，语音障碍指数显著降低。为了验证这些发现，需要进行更多的研究，在解释这些结果时需要谨慎，因为许多比较的选择研究数量有限。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Iranian Journal of Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

2.20

自引率

7.10%

发文量

300

审稿时长

3-8 weeks

期刊介绍： Iranian Journal of Public Health has been continuously published since 1971, as the only Journal in all health domains, with wide distribution (including WHO in Geneva and Cairo) in two languages (English and Persian). From 2001 issue, the Journal is published only in English language. During the last 41 years more than 2000 scientific research papers, results of health activities, surveys and services, have been published in this Journal. To meet the increasing demand of respected researchers, as of January 2012, the Journal is published monthly. I wish this will assist to promote the level of global knowledge. The main topics that the Journal would welcome are: Bioethics, Disaster and Health, Entomology, Epidemiology, Health and Environment, Health Economics, Health Services, Immunology, Medical Genetics, Mental Health, Microbiology, Nutrition and Food Safety, Occupational Health, Oral Health. We would be very delighted to receive your Original papers, Review Articles, Short communications, Case reports and Scientific Letters to the Editor on the above mentioned research areas.