Iranian Journal of Public Health最新文献

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The Effects of Health and Unmet Dental Care Needs on the Health-Related Quality of Life in Korea Older Adults: A Nationwide Study. 健康和未满足的牙科保健需求对韩国老年人与健康相关的生活质量的影响:一项全国性研究。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Jiwoo Jung, Jinna Yu, Nam-Jun Kim, Yeunhee Kwak
{"title":"The Effects of Health and Unmet Dental Care Needs on the Health-Related Quality of Life in Korea Older Adults: A Nationwide Study.","authors":"Jiwoo Jung, Jinna Yu, Nam-Jun Kim, Yeunhee Kwak","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The purpose of this cross-sectional study was to assess the relationship between oral health, unmet dental needs and health-related quality of life in South Korea older adults.</p><p><strong>Methods: </strong>The present study used raw data from the 2019~2020 Korea National Health and Nutrition Examination Survey, and analyzed 4956 participants aged over 65 yr. Hierarchical multiple regression analysis was used for associations between oral health, unmet dental needs, and HRQoL.</p><p><strong>Results: </strong>The EQ-5D index differed according to tooth pain, chewing difficulty, speaking problem, subjective oral health status, oral examination, and unmet dental care needs (<i>P</i><0.001). In the model 2, male, under 75 yr of age, high school graduate or higher, employed, living with a spouse, no stress, good subjective health status, no speaking problem, and no unmet dental care needs were associated with higher EQ-5D index (Adj R2 = 27.6%, <i>P</i><0.001).</p><p><strong>Conclusion: </strong>To improve the HRQoL of older adults in South Korea, oral health problems need to be minimized through oral disease prevention and oral health education programs.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comparison between Serum 25-Hydroxyvitamin D3 Levels and Serum Ferritin in Children and Adolescents with Iron Deficiency Anemia, Thalassemia Minor, Thalassemia Major and Healthy People. 缺铁性贫血、轻型地中海贫血、重型地中海贫血儿童和青少年与健康人血清 25-羟维生素 D3 水平和血清铁蛋白的比较。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Akram Hemmatipour, Bijan Kikhaei, Razieh Jalkani, Mansour Ahmadnejad, Farhad Soleimanzadeh, Dariush Rokhafrooz
{"title":"A Comparison between Serum 25-Hydroxyvitamin D3 Levels and Serum Ferritin in Children and Adolescents with Iron Deficiency Anemia, Thalassemia Minor, Thalassemia Major and Healthy People.","authors":"Akram Hemmatipour, Bijan Kikhaei, Razieh Jalkani, Mansour Ahmadnejad, Farhad Soleimanzadeh, Dariush Rokhafrooz","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>We aimed to determine the level of serum vitamin D and serum ferritin in four groups' children and adolescents.</p><p><strong>Methods: </strong>This descriptive/analytical study was conducted in 2019 on children and adolescents with thalassemia aged 7-18 years in Ahvaz, Iran. Overall, 160 patients with the target inclusion and exclusion criteria were assigned into four groups (n=40) of people with thalassemia minor, thalassemia major, iron deficiency anemia and healthy individuals. The level of ferritin and vitamin D was assessed. Mann-Whitney test, Wilcoxon test and Spearman's correlation test were used as well as SPSS Statistics V21.</p><p><strong>Results: </strong>The mean age of the participants was 13.07 ± 3.82 yr and 100 people (62.5%) were male. In terms of vitamin D deficiency, 16 people (40%) had severe deficiency in iron deficiency group. The highest level of ferritin was found in thalassemia major group and the lowest in iron deficiency group. Regarding the level of vitamin D and ferritin in the healthy group, there was a statistically significant difference between mean vitamin D and serum ferritin levels (<i>P</i>=0.027). In iron deficiency group, this level of ferritin was observed with mild deficiency (<i>P</i>=0.017). In thalassemia major group, the increase in ferritin was associated with severe vitamin D deficiency (<i>P</i>=0.05.</p><p><strong>Conclusion: </strong>Severe vitamin D is seen in thalassemia major due to the increase in ferritin, but moderate deficiency of this vitamin in healthy people and mild deficiency in iron deficiency anemia group was observed considering the normal levels of ferritin.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Multi-Sensory Stimulation on Apathy Symptoms in Elderly Patients with Alzheimer's Disease. 多感官刺激对老年痴呆症患者冷漠症状的影响
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Yang Li, Teng Zhao, Yu Wang, Xuewen Yang, Yinghui Lv, Shumei Li, Xiujun Yang, Li Li
{"title":"Effects of Multi-Sensory Stimulation on Apathy Symptoms in Elderly Patients with Alzheimer's Disease.","authors":"Yang Li, Teng Zhao, Yu Wang, Xuewen Yang, Yinghui Lv, Shumei Li, Xiujun Yang, Li Li","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>We aimed to explore the effect of multi-sensory stimulation on apathy symptoms in elderly patients with Alzheimer's disease (AD).</p><p><strong>Methods: </strong>Eighty elderly patients with AD admitted to the Third Affiliated Hospital of Qiqihar Medical University, China from January 2022 to February 2023 were selected as the research objects by convenient sampling method. According to the random number table, they were divided into intervention group and control group, with 40 cases in each group. The control group was given routine nursing, while the intervention group was given multi-sensory stimulation based on this nursing. Apathy evaluation scale (AES), Behavioral pathology in Alzheimer's disease rating scale (BEHAVE-AD) and Quality of Life Scale for dementia patients (QoL-AD) were used to compare the results.</p><p><strong>Results: </strong>Compared with the control group, the scores of AES and BEHAVE-AD in intervention group were lower (<i>t</i> was -7.312 and 11.88 respectively, <i>P</i> < 0.05), and the scores of QoL-AD in intervention group were significantly higher than those in control group were (<i>t</i> was -15.311, <i>P</i> < 0.01).</p><p><strong>Conclusion: </strong>Multi-sensory stimulation can relieve apathy symptoms, mental and behavioral symptoms and improve the quality of life of elderly patients with AD, which is worth popularizing in clinical practice.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatial Epidemiology and Temporal Trend of Brucellosis in Iran Using Geographic Information System (GIS) and Join Point Regression Analysis: An Ecological 10-Year Study. 利用地理信息系统 (GIS) 和连接点回归分析法研究伊朗布鲁氏菌病的空间流行病学和时间趋势:一项为期 10 年的生态研究。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Sajjad Rahimi Pordanjani, Elaheh Mazaheri, Farshid Farivar, Masoudeh Babakhanian, Hasan Askarpour, Somayeh Derakhshan
{"title":"Spatial Epidemiology and Temporal Trend of Brucellosis in Iran Using Geographic Information System (GIS) and Join Point Regression Analysis: An Ecological 10-Year Study.","authors":"Sajjad Rahimi Pordanjani, Elaheh Mazaheri, Farshid Farivar, Masoudeh Babakhanian, Hasan Askarpour, Somayeh Derakhshan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Brucellosis is one of the common diseases between humans and animals. We aimed to assess the annual incidence rate, the geographical distribution of Malta fever using GIS and its time trend.</p><p><strong>Methods: </strong>This was an ecology study carried out in exploratory mixed design. The study population was the individuals with brucellosis in Iran during the years 2009-2018. Data analysis has been done using Joinpoint regression analysis and GIS at a significant level of α = 0.05.</p><p><strong>Results: </strong>The average annual incidence rate of the disease rate was 19.91 per one hundred thousand people. The trend of the changes in the incidence between 2009 and 2018 has increased and the Annual Average Percent Change increased by 4.6%. However, a joinpoint was observed in 2014 and the incidence has changed significantly at this point in time, so that the annual incidence of the disease has increased more strongly between 2009 and 2014 (APC=17.1%) and then from 2014 to 2018, the incidence of the disease has decrease (APC=-9.2%). The spatial distribution showed that the western and northwestern provinces have high incidence rate, but the northern and southern provinces have low incidence rate.</p><p><strong>Conclusion: </strong>The incidence of brucellosis in Iran is higher than in developed countries and similar to developing countries. Ten-year trend of disease incidence increased slightly, but it has decreased in recent years. It is necessary to improve the surveillance system and increase facilities for prevention and treatment in the high-risk areas including the west and northwest of Iran.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Diagnostic Performance of 68Ga-PSMA-11 PET/MRI for the Biochemically Recurrent Prostate Cancer: A Systematic Review and Meta-analysis. 68Ga-PSMA-11 PET/MRI 对生化复发前列腺癌的诊断性能:系统回顾与元分析》。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-06-01
Dan Wang, Zong-Hao Wang, Chun-Bao Wang, Zhi-Chun Wu
{"title":"The Diagnostic Performance of <sup>68</sup>Ga-PSMA-11 PET/MRI for the Biochemically Recurrent Prostate Cancer: A Systematic Review and Meta-analysis.","authors":"Dan Wang, Zong-Hao Wang, Chun-Bao Wang, Zhi-Chun Wu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Our meta-analysis aimed to evaluate the diagnostic performance of <sup>68</sup>Ga-PSMA-11 PET/MRI for biochemical recurrence of prostate cancer.</p><p><strong>Methods: </strong>We systematically and comprehensively searched all available studies until May 2023 in the PubMed and Embase databases. Studies evaluating <sup>68</sup>Ga-PSMA-11 PET/MRI in men with prostate cancer biochemical recurrence were included. We appraised the quality of studies using a tailored Quality Assessment of Diagnostic Accuracy Studies-2 (QUADAS-2) tool. For each meta-analysis, we used the DerSimonian and Laird method. We first transformed proportions with the Freeman-Tukey double arcsine transformation, and then confidence intervals were calculated using the Jackson method. Meta-regression and sensitivity analysis were conducted to explore heterogeneity sources. Furthermore, we conducted subgroup analysis according to the PSA levels.</p><p><strong>Results: </strong>Overall, 13 studies with 738 patients were included in the analysis. The pooled overall detection rates of <sup>68</sup>Ga-PSMA-11 PET/MRI in detecting recurrent PCa after definitive treatment were 74% (95% CI, 68%-79%). For patients with PSA under 0.5 ng/mL, the detection rate was 55 %. The detection rates were 79 %, 76 % and 87 % for the subgroup PSA levels of 0.5-0.99, 1.0-1.99 and over 2.0 ng/mL.</p><p><strong>Conclusion: </strong><sup>68</sup>Ga-PSMA-11 PET/MRI has a good detection rate for biochemical recurrence of prostate cancer. However, large sample, multi-center studies are still needed to verify and expand on our conclusion.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Susceptibility Status of Several Field-Collected German Cockroaches (Blattella germanica) to a Pyrethroid Insecticide and Molecular Detection of Knockdown Resistance (kdr). 几种野外采集的德国蟑螂(Blattella germanica)对拟除虫菊酯类杀虫剂的敏感性状况以及基因敲除抗性(kdr)的分子检测。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15573
Kamal Dashti, Saber Gholizadeh, Morteza Zaim, Mozhgan Baniardalani, Hamidreza Basseri
{"title":"Susceptibility Status of Several Field-Collected German Cockroaches (<i>Blattella germanica</i>) to a Pyrethroid Insecticide and Molecular Detection of Knockdown Resistance (<i>kdr</i>).","authors":"Kamal Dashti, Saber Gholizadeh, Morteza Zaim, Mozhgan Baniardalani, Hamidreza Basseri","doi":"10.18502/ijph.v53i4.15573","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15573","url":null,"abstract":"<p><strong>Background: </strong>High frequency of insecticide used to control German cockroaches may lead to insecticide resistance development. We aimed to compare the level of insecticide resistance and heterogeneity in insecticide resistance of field-collected German cockroaches in eight selected zones of Mashhad City, Razavi Khorasan Province, Iran.</p><p><strong>Methods: </strong>The present study was conducted from October 2019 to May 2021. Adult and nymphs of German cockroaches were collected from infested restaurants or hotels in eight zones of Mashhad City and then colonized in an insectarium. The cockroaches were subjected to bioassay against cypermethrin insecticide. In addition, the genomic DNA of each cockroach population was analyzed in the region where the <i>kdr</i> mutations reside in the German cockroach.</p><p><strong>Results: </strong>The LT<sub>50</sub> values against cypermethrin in the susceptible strain (SS) and eight field-collected strains so varied from 17.52 to 95.36 min. The resistance ratio of the strains was also different in response to the insecticide. The similarity of multiple sequence alignments at the amino acid level was 97.5%-100%. An exon 20 transversion mutation and a nonsynonymous substitution were found. The L1014F substitution was detected in 83.4% of the cockroach samples.</p><p><strong>Conclusion: </strong>The field-collected strains were resistant to cypermethrin at different levels. Furthermore, the molecular study confirms the heterogeneity in the level of resistance among eight strains. Therefore, eight strains might have a different history of insecticide treatment.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of Triglyceride-Glucose Index between Patients with Gallstone and Healthy Individuals. 胆石症患者与健康人甘油三酯-葡萄糖指数的比较
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15565
Semra Özkan Öztürk
{"title":"Comparison of Triglyceride-Glucose Index between Patients with Gallstone and Healthy Individuals.","authors":"Semra Özkan Öztürk","doi":"10.18502/ijph.v53i4.15565","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15565","url":null,"abstract":"<p><strong>Background: </strong>Triglyceride-glucose index is a product of triglycerides and fasting plasma glucose (FPG) and is a new index of insulin resistance found to correlate with direct measurements. This study aimed to evaluate the relationship between gallstones and triglyceride-glucose index (TGI).</p><p><strong>Methods: </strong>A total of 210 patients were included in this retrospective study. Overall, 105 patients with gallstones were included in the patient group. Patients with diabetes mellitus, chronic diseases, malignant diseases, and patients using cholesterol-lowering drugs were excluded from the study. Healthy individuals (105 cases) were selected for the control group. TGI was calculated separately for each individual using the following formula: (TGI) = ln (fasting TG (mg/dL) × fasting glucose (mg/dL)/2).</p><p><strong>Results: </strong>Plasma triglyceride levels were significantly higher in patients with gallstones compared to the control group (<i>P</i>=0.001). Plasma HDL, LDL, and total cholesterol did not differ between the groups (<i>P</i>>0.05). Fasting blood glucose was significantly higher in patients with gallstones compared to the control group (<i>P</i>=0.001). The triglyceride glucose index was significantly higher in patients with gallstones compared to the control group (<i>P</i><0.001). When the relationship between body mass index and TGI was analyzed, TGI was lower in patients with normal BMI compared to overweight or obese patients (<i>P</i><0.001).</p><p><strong>Conclusion: </strong>Increased triglyceride/glucose index in patients with gallstones is an indicator of insulin resistance. It is instrumental in demonstrating the presence of insulin resistance in patients with gallstones and may be a useful guide in earlier detection, prevention, and treatment of insulin resistance.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of the Effectiveness of Cognitive-Behavioral Therapy and Acceptance and Commitment-Based Therapy on Anxiety Sensitivity in Adolescents with Social Anxiety Disorder. 认知行为疗法与接纳与承诺疗法对社交焦虑症青少年焦虑敏感性的疗效比较》(Cognitive-Behavioral Therapy and Acceptance and Commitment-Based Therapy on Anxiety Sensitivity in Adolescents with Social Anxiety Disorder)。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15575
Shirin Ebrahimi, Naeimeh Moheb, Marziyeh Alivandi Vafa
{"title":"Comparison of the Effectiveness of Cognitive-Behavioral Therapy and Acceptance and Commitment-Based Therapy on Anxiety Sensitivity in Adolescents with Social Anxiety Disorder.","authors":"Shirin Ebrahimi, Naeimeh Moheb, Marziyeh Alivandi Vafa","doi":"10.18502/ijph.v53i4.15575","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15575","url":null,"abstract":"","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation the Application of Karyotype Analysis and Chromosome Microarray in Prenatal Diagnosis. 评估核型分析和染色体微阵列在产前诊断中的应用。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15560
Huafeng Li, Yongli Li, Yanli Zhang, Jinping Zhu, Yuqiang Huang
{"title":"Evaluation the Application of Karyotype Analysis and Chromosome Microarray in Prenatal Diagnosis.","authors":"Huafeng Li, Yongli Li, Yanli Zhang, Jinping Zhu, Yuqiang Huang","doi":"10.18502/ijph.v53i4.15560","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15560","url":null,"abstract":"<p><strong>Background: </strong>We aimed to compare the difference of the chromosomal abnormalities using karyotype analysis and chromosomal microarray (CMA) as well as to evaluate their application in different prenatal diagnosis indications.</p><p><strong>Methods: </strong>Overall, 3007 pregnant women with prenatal diagnosis indications from Medical Genetics Department of Linyi Women and Children's Health Care Hospital, who underwent standard G-banded karyotype analysis and CMA, were enrolled from 2018-2022. G-banded karyotype analysis and CMA were undergone simultaneously. All fetuses with genetic variants were enrolled for further analyzing. The frequency and differences of chromosomal abnormalities of the two methods were compared in different prenatal diagnosis indications groups.</p><p><strong>Results: </strong>CMA improved 4.09% (123/3007) of genetic changes compared karyotype analysis. CMA is on par with karyotyping for detection of aneuploidies and gross unbalanced rearrangements. Serological screening and ultrasound abnormalities were the main indications of prenatal diagnosis. The detection rate of chromosomal abnormalities was highest in non-invasive prenatal testing (NIPT) abnormal group. In the ultrasound abnormality group, the detection rate of genetic variants in nuchal translucency (NT) increased group was higher than other subgroups and there was statistically significant difference in the detection rate of pCNVs. CMA can detect 5.57% (40/718) more genetic abnormalities in ultrasound abnormality group on the normal karyotype. CMA improved 0.67% (20/3007) of genetic changes with clinically significant compared karyotype, brought 3.42% (103/3007) of variants with uncertain significance (VOUS).</p><p><strong>Conclusion: </strong>CMA identified additional, clinically significant genetic variants on the basis of normal karyotype analysis, brought a proportion of unclear significant variants. All the pregnant women accepted amniocentesis should be informed about their characteristics of karyotype analysis and CMA by genetic counselors.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value-Based Market Segmentation of West Asian Medical Tourism Market: A Case of Iran. 基于价值的西亚医疗旅游市场细分:伊朗案例。
IF 1.3 4区 医学
Iranian Journal of Public Health Pub Date : 2024-04-01 DOI: 10.18502/ijph.v53i4.15570
Leila Torkzadeh, Habib Jalilian, Hojjat Rahmani, Milad Bakhshi, Saeed Hashemzadeh, Mohammad Faryabi, Rahim Khodayari-Zarnaq
{"title":"Value-Based Market Segmentation of West Asian Medical Tourism Market: A Case of Iran.","authors":"Leila Torkzadeh, Habib Jalilian, Hojjat Rahmani, Milad Bakhshi, Saeed Hashemzadeh, Mohammad Faryabi, Rahim Khodayari-Zarnaq","doi":"10.18502/ijph.v53i4.15570","DOIUrl":"https://doi.org/10.18502/ijph.v53i4.15570","url":null,"abstract":"<p><strong>Background: </strong>Identifying different groups of customers and their preferences and needs enable countries to gain a competitive advantage in the medical tourism market. We aimed to segment medical tourists from West Asian countries seeking medical services in Iran.</p><p><strong>Methods: </strong>This cross-sectional study was conducted on 596 medical tourists who sought medical services in Iran in 2021. Data were collected using a valid questionnaire. Segmentation was performed based on medical tourism attributes (medical, destination, and tourism attributes), using cluster analysis methods; wards, and K means. The segments ' evaluation and profiling were conducted using discriminant analysis, chi-square, and oneway ANOVA tests.</p><p><strong>Results: </strong>Our study divided the market into five segments: health seekers (3.8%), health and destination seekers (8.9%), tourism seekers (17.8%), infrastructure seekers (10.23%), and perfectionism (59.45%). In all segments, the health attributes were of high importance. The perfectionism segment registered the highest score in all three attributes (more than 5 of 6).</p><p><strong>Conclusion: </strong>Improving health attributes and offering luxurious medical services can be the main strategy for Iran to attract the most medical tourists and achieve a good position in this marketplace. The implication of this study is policymaking for targeting the most profitable segment of this marketplace.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11493577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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