Iranian Journal of Public Health最新文献

{"title":"COMMENT on \"Trend Analysis of Suicide Mortality and Years of Life Lost From 2016 to 2021 in Southern Iran\".","authors":"Mohammad Jalilian","doi":"10.18502/ijph.v53i8.16299","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16299","url":null,"abstract":"","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1907-1908"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Low Protein Diet on Patients with Cardiovascular Disease: A Systematic Review and Meta-Analysis.","authors":"Mingtao Ding, Lei Liu","doi":"10.18502/ijph.v53i8.16275","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16275","url":null,"abstract":"<p><strong>Background: </strong>Low protein diet plays an important role in cardiovascular diseases. However, exact role is unclear so far. We aimed to find out the effect of low protein diet on patients with cardiovascular disease.</p><p><strong>Methods: </strong>The PRISMA guidelines were followed throughout the research project until 10th Apr 2023. MeSH phrases and Boolean operators were used to search PubMed for suitable studies. The entire estimate was expressed as a 95% confidence interval around the mean difference. The model was picked because of the discrepancies found in the research. Choi's Q test and I² statistics were used to determine the degree of variation between experiments. The funnel plot was used to qualitatively examine the publishing bias.</p><p><strong>Results: </strong>Low-protein diets have a greater impact on waist circumference [-8.82 (-9.51, -8.13), P<0000.1] and high-density lipoprotein (HDL) [-0.05 (-0.07, -0.03), <i>P</i><0000.1] alteration than non-LPD diets, as measured by the standard mean difference (SMD). Further, significant changes were observed in weight loss [1.51 (1.25, 1.77), <i>P</i><0.00001], BMI, [0.46 (0.25, 0.67), <i>P</i><0.0001], change systolic [2.48 (1.20, 3.77), <i>P</i>=0.0002] and diastolic blood pressure [1.49 (0.72, 2.26), <i>P</i>=0.0002], low density lipoprotein [0.09 (0.06, 0.12), <i>P</i><0.00001], triglyceride [0.52 (0.49, 0.55), <i>P</i><0.00001], in non-LPD group as compared to LPD group.</p><p><strong>Conclusion: </strong>The results indicated the role of low protein diet on patients with cardiovascular disease.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1695-1708"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioinformatics Analysis of Differentially Expressed Genes in Carpal Tunnel Syndrome Using RNA Sequencing.","authors":"Maziar Oveisee, Akram Gholipour, Mahrokh Bagheri Moghaddam, Mahshid Malakootian","doi":"10.18502/ijph.v53i8.16293","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16293","url":null,"abstract":"<p><strong>Background: </strong>Carpal tunnel syndrome (CTS) is a common disease resulting from the median nerve entrapment at the wrist. Although CTS (prevalence=5%-10% in the general population) is the most common neuropathy, its molecular mechanisms need elucidation. We used bioinformatics to detect genes with differential expressions in CTS and introduce the molecular regulatory noncoding RNAs and signaling pathways involved.</p><p><strong>Methods: </strong>The raw files of the RNA sequencing of CTS patients and controls were obtained from GEO (accession: GSE108023), and the samples were analyzed. Differentially expressed genes were isolated using DESeq2 R. Functional analyses were conducted on the signaling pathways, biological processes, molecular functions, and cellular components of the differentially expressed genes. Additionally, interactions between the most differentially expressed genes and miRNAs and lncRNAs were investigated bioinformatically.</p><p><strong>Results: </strong>Upregulation and downregulation were observed in 790 and 922 genes, respectively. The signaling pathway analysis identified the metabolism pathways of arachidonic acid, linoleic acid, and tyrosine as the most significant pathways in CTS. Moreover, <i>PLA2G2D</i> and <i>PLA2G2A</i> with upregulated expressions and <i>PLA2G2F, PLA2G4F, PLA2G4D, PLA2G3,</i> and <i>PLA2G4E</i> with downregulated expressions were genes from the phospholipase family playing significant roles in the pathways. Further analyses demonstrated that hsa-miR-3150b-3p targeted <i>PLA2G2A</i> and <i>PLA2G4F</i>, and RP11-573D15.8-018 lncRNA had regulatory interactions with the aforementioned genes.</p><p><strong>Conclusion: </strong>Molecular studies on CTS will clarify the involved signaling pathways and provide critical data for biomedical research, drug development, and clinical applications.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1871-1882"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to \"COMMENT on Trend Analysis of Suicide Mortality and Years of Life Lost From 2016 to 2021 in Southern Iran\".","authors":"Habibollah Azarbakhsh, Milad Ahmadi Marzaleh, Iman Shakibkhah","doi":"10.18502/ijph.v53i8.16300","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16300","url":null,"abstract":"","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1909"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect on Non-Small Cell Lung Cancer after Combination of Driver Gene Mutations and Anti-PD-1/PD-L1 Immunotherapy as Well as Chemotherapy.","authors":"Zhengming Huang, Long Yu, Weisong Chen, Dan Zhu, Hui Chen","doi":"10.18502/ijph.v53i8.16280","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16280","url":null,"abstract":"<p><strong>Background: </strong>We aimed to reveal the correlation between pathological indicators and PD-L1, between gene mutation status in lung cancer through clinico-pathological data and lung cancer-related gene mutation and PD-L1 expression analysis.</p><p><strong>Methods: </strong>The study was conducted in Jinhua Municipal Central Hospital, Zhejiang, China from 2017 to 2022. PD-L1 testing and targeted gene mutations detection were evaluated. The clinical characteristics of these non-small cell lung cancer (NSCLC) samples have been obtained. The groups (LUAD, n=142; LUSC, n=143) were grouped according to clinico-pathological features and PD-L1 expression (Yes/No or High/Low), and the clinico-pathological and genetic and molecular features and correlation with PD-L1 expression were compared across the above groups. Comparisons and analyses were made between different treatment schemes.</p><p><strong>Results: </strong>Lung adenocarcinoma (LUAD, n=142) and lung squamous carcinoma (LUSC, n=143) samples were enrolled (median age: 64 years old). Pleural invasion and M staging were significantly different from PD-L1 alterations (<i>P</i><0.05). The percentage of patients with PD-L1 tumor proportion score (TPS)≥50% was 36.24% and the percentage of patients with PD-L1 TPS<50% was 29.53%. The percentage of patients with PD-L1 high-expressed and treated by immunotherapy was 75.93% and 63.41% experienced Partial Response/Complete Response. The mutations ratio of <i>EGFR</i>, <i>ALK</i>, <i>KRAS</i>, <i>MET</i>, <i>RET</i> and <i>TP53</i> were 28.86%, 1.34%, 6.04%, 0.67%, 1.34% and 0.67%, respectively. <i>KRAS</i> mutation was significantly different from PD-L1 alterations (<i>P</i><0.01).</p><p><strong>Conclusion: </strong>There are individual differences in PD-L1 expression, which can also vary depending on the different clinical features. Specific molecular features correlate with differential PD-L1 expression and may influence the response to therapy.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1754-1768"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475187/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mortality Rate and Years of Life Lost Due to Breast and Gynecologic Cancers in Southern Iran 2004-2019: A Population-Based Study.","authors":"Habibollah Azarbakhsh, Alireza Heiran, Amir Askarinejad, Jafar Hassanzadeh, Maryam Janfada, Alireza Mirahmadizadeh","doi":"10.18502/ijph.v53i8.16295","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16295","url":null,"abstract":"<p><strong>Background: </strong>There is an increase in the incidence of breast and gynecologic cancers in Iran during the last three decades. Literature is inadequate about the Years of Life Lost (YLL) attributed to these cancers in Iran.</p><p><strong>Methods: </strong>Mortality data due to these cancers amongst females aged >20 yr from 2004 to 2019 was acquired from \"Electronic Death Registry System\", Fars Province, Iran. Using local health centers' databases and national census reports from 1996 to 2016, the age-standardized incidence rate (ASR) per 100,000 people were estimated. YLLs were calculated using the WHO's 2015 \"YLL template\".</p><p><strong>Results: </strong>During 2004-2019, 1886 and 829 deaths occurred due to breast and gynecologic cancers, respectively. The ASR due to breast and gynecologic cancers showed a significant increasing trend (<i>P</i><0.001 for each). The total YLL due to breast, cervical/uterine/vaginal/vulvar, and ovary cancers' deaths in the 16-year period were 33,077, 7,172 and 6,584 yr, respectively. The highest YLLs were observed in 50-59-year-old females, followed by 40-49- and 60-69-year-old females. The 16- year trend of YLL rate due to premature mortality in breast cancer, ovary cancer and cervix cancer was increasing: annual percent change (APC) was 7.6% (95% CI: 5.5-9.7, <i>P</i><0.001), 19.0% (95% CI: 12.2-26.1, <i>P</i><0.001) and 9.2% (95% CI: -9.2 to 31.3, <i>P</i>>0.05, respectively.</p><p><strong>Conclusion: </strong>Mortality rate and YLLs due to breast and gynecologic cancers have been increased in southern Iran during the last twenty years. Early detection programs and allocating treatments at early stages should be prioritized.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1890-1897"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Vulnerable Are the Elderly in Road Traffic-Autopsy Study?","authors":"Živana Slović, Ivana Andrić, Danijela Todorović, Filip Mihajlović, Snežana Đorđević, Olgica Mihaljević, Miloš Todorović, Katarina Vitošević","doi":"10.18502/ijph.v53i8.16285","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16285","url":null,"abstract":"<p><strong>Background: </strong>The aim of this study was to analyze characteristic and pattern of road traffic injuries in this special aging group, as well to examine the relevance of certain injuries or risk factors to outliving the injuries.</p><p><strong>Methods: </strong>This epidemiological, analytical, retrospective, autopsy study investigated the road traffic deaths for period between 2001 and 2022. The subjects were divided into two age groups, elderly (65 years and older) and middle aged (16-64 years old).</p><p><strong>Results: </strong>We included 213 (32%) elderly participants out of all 665 RTA subjects who died from sustained injuries or complications of the injuries. The majority of elderly subjects (61%) were pedestrians, and elderly participants in RTA were more likely to survive the injuries. The most common injuries among the elderly in all group of participants were chest injuries 81% (and among them, rib fractures were present in 76%). Cranio-cerebral injury is the most common cause of death in RTA subjects, singular (45%) or in combination with other causes. In the group of elderly RTA subjects complication of injury is represented in 36 subjects (17%), while as cause of death is represented in 22 subjects (10%). Elderly are less likely to have positive BAC, and even in cases when BAC was increased, the levels were on the lower scale.</p><p><strong>Conclusion: </strong>More effort should be made to enhance road safety for elderly pedestrians, especially considering the expected rapid growth in the elderly population.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1796-1804"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mediterranean Diet Adherence and Eating Disorders Screening in Adults with Celiac Disease in Morocco.","authors":"Btihaj Al Ibrahmi, Abdellatif Bour","doi":"10.18502/ijph.v53i8.16282","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16282","url":null,"abstract":"<p><strong>Background: </strong>Celiac disease is a chronic autoimmune disease of the small intestine, related to gluten intolerance occurring in genetically predisposed patients. This study aimed to evaluate Mediterranean diet adherence, screen eating disorders and establish the relationship between Mediterranean diet and eating disorders.</p><p><strong>Methods: </strong>This study included 81 adults with celiac disease, and 85 without celiac disease from Rabat-Sale-Kenitra hospitals between May 2022 and Nov 2022. The Mediterranean Diet Serving Score (MDSS) questionnaire was used to determine adherence to the Mediterranean diet and SCOFF questionnaire was used to screen eating disorders.</p><p><strong>Results: </strong>The results showed a significant difference between the two groups in age (<i>P</i>=0.000), weight (<i>P</i>=0.041), height (<i>P</i>=0.000) and non-adherence to Mediterranean diet (<i>P</i>=0.032). Participants without celiac disease reported a significantly (<i>P</i>=0.032) lower adherence score to the Mediterranean diet (62.35%) than participants with celiac disease (29.62%). Additionally, the results of the Khi2 test which revealed a significant association between MDSS and SCOFF (<i>P</i>=0.024). In addition, based on logistic regression the Mediterranean diet Serving Score was significantly associated with eating disorders (<i>P</i>=0.025) in adults with celiac disease, on the other hand, weight, height, BMI and MDSS were significantly associated with eating disorders in adults without celiac disease.</p><p><strong>Conclusion: </strong>Our study showed good adherence to the Mediterranean diet by celiac adults so it can be assumed that the Mediterranean diet could have a protective effect against eating disorders in celiac patients.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1769-1776"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475186/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation Therapy for Improvement of Body Contour: A Retrospective Study on Middle Eastern Participants.","authors":"Seyed Ebrahim Eskandari, Aniseh Samadi, Sina Kardeh, Yahya Dowlati, Hasti Ahmadian Yazdi, Alireza Firooz","doi":"10.18502/ijph.v53i8.16291","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16291","url":null,"abstract":"<p><strong>Background: </strong>The rising demand for body contouring and concerns about side effects of invasive surgical procedures have led to advances in providing new non-invasive alternative methods for weight reduction. The current retrospective study investigated the safety and efficacy of photobiomodulation technology in reducing local obesity in Middle Eastern participants.</p><p><strong>Methods: </strong>Providing data about body circumferences of 30 participants, with body mass index (BMI) >28 and localized obesity in the abdomen, thighs, buttocks, or arms were included in the final data synthesis. All the records were received at least 4 treatment sessions with the photobiomodulation technology (Volcano device) in Center for Research and training in Skin Diseases and Leprosy (CRTSDL) during June 2022-September 2022 Reductions in body standing circumferences as well as reported adverse effects and participants' satisfaction were retrospectively evaluated and reported. .</p><p><strong>Results: </strong>The extricated data included 30 females participants aged 42.06 ± 11.6 years and localized obesity in the abdomen (15 cases), thighs (7 cases), hip (one case) and arms (7 cases). While BMIs were not significantly different from the baseline, abdominal, arm and tight circumferences showed a significant decline after receiving 4 and 6 treatment sessions (<i>P</i><0.01).. There was no report of adverse effect and overall satisfaction was an \"excellent\" grade.</p><p><strong>Conclusion: </strong>This study demonstrated the effectiveness and safety of photobiomodulation in reduction of circumferential size in abdomen, buttock, thigh, and arm areas in Middle Eastern participants with high patient satisfaction and acceptable safety profile.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1858-1863"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Effects of Long-Term Exposure to Fine Particulate Matter (PM_2.5) on Depressive Mood among Korean Older Adults Using Multilevel Analysis.","authors":"Kyunghee Jo","doi":"10.18502/ijph.v53i8.16284","DOIUrl":"https://doi.org/10.18502/ijph.v53i8.16284","url":null,"abstract":"<p><strong>Background: </strong>The harmful effects of particulate matter (PM) are amplified in older adults, who experience a decline in physiological function, reducing their ability to expel and detoxify inhaled PM. Moreover, older adults may be more vulnerable to fine particulate toxicity due to underlying medical conditions. We assessed the effects of long-term exposure to fine particulate matter (PM_2.5) on depressive mood (DM) in adults aged > 65 yr using community-based data.</p><p><strong>Methods: </strong>In the 2017, Korean Community Health Survey (KCHS) data, data of PM_2.5 and community factors were constructed based on participants who responded to DM in a sample of 67,802 individuals. To evaluate the effect of PM_2.5 on DM among older adults, a multilevel regression model was constructed using individual-(KCHS) and community-level data (PM_2.5, green area per capita, urban area, social welfare budget, health, and social business). For PM_2.5, an independent variable, quartiles were used to classify regions according to concentration.</p><p><strong>Results: </strong>A positive correlation was found between PM_2.5 and DM of older adults. Compared to Q1, the odds ratio increased to 1.15 (95% CI 0.76-1.74) in Q2, 1.55 (95% CI 1.02-2.35) in Q3, and 1.60 (95% CI 1.16-2.20) in Q4.</p><p><strong>Conclusion: </strong>DM may increase in older individuals living in areas with high PM_2.5. Systematic mental health management is required for older individuals residing in such areas.</p>","PeriodicalId":49173,"journal":{"name":"Iranian Journal of Public Health","volume":"53 8","pages":"1785-1795"},"PeriodicalIF":1.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11475172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}