Developmental Cognitive Neuroscience最新文献_第5页

Corrigendum to “A multi-sample evaluation of the measurement structure and function of the modified monetary incentive delay task in adolescents” [Dev. Cogn. Neurosci. 65 (2024) 1–17] “修正后的青少年货币激励延迟任务的测量结构和功能的多样本评价”[发展与管理]。神经科学学报，65(2024):1-17。

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-26 DOI: 10.1016/j.dcn.2025.101533

Michael I. Demidenko, Jeanette A. Mumford, Nilam Ram, Russell A. Poldrack

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Phonological decoding ability is associated with fiber density of the left arcuate fasciculus longitudinally across reading development 语音解码能力与纵向阅读发育的左弓状束纤维密度有关

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-25 DOI: 10.1016/j.dcn.2025.101537

Meaghan V. Perdue , Bryce L. Geeraert , Kathryn Y. Manning , Deborah Dewey , Catherine Lebel

{"title":"Phonological decoding ability is associated with fiber density of the left arcuate fasciculus longitudinally across reading development","authors":"Meaghan V. Perdue , Bryce L. Geeraert , Kathryn Y. Manning , Deborah Dewey , Catherine Lebel","doi":"10.1016/j.dcn.2025.101537","DOIUrl":"10.1016/j.dcn.2025.101537","url":null,"abstract":"<div><div>Numerous studies have linked reading ability to white matter microstructure using diffusion tensor imaging, but findings have been inconsistent and lack specificity. Fiber-specific diffusion-weighted magnetic resonance imaging (dMRI) models offer enhanced precision in measuring specific microstructural features, but they have not yet been applied to examine associations between reading ability and white matter microstructure development as children learn to read. We applied constrained spherical deconvolution (CSD) and fiber-specific modelling to characterize developmental changes in fiber density of key white matter tracts of the reading network, and investigated associations between tract-wise fiber density and children’s phonological decoding abilities. Fiber density was measured from ages 2–13 years, and decoding ability (pseudoword reading) was assessed at ages 6 years and older. Higher decoding ability was associated with greater fiber density in the left arcuate fasciculus, and effects remained consistent over time. Follow-up analysis revealed that asymmetry changes in the arcuate fasciculus were moderated by decoding ability: good decoders showed leftward asymmetry from early childhood onward, while poorer decoders shifted toward leftward asymmetry over time. These results suggest that densely organized fibers in the left arcuate fasciculus serve as a foundation for the development of reading skills from the pre-reading stage through fluent reading.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101537"},"PeriodicalIF":4.6,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Developmental trajectories of gyrification and sulcal morphometrics in children and adolescents at high familial risk for bipolar disorder or schizophrenia 双相情感障碍或精神分裂症高家族风险儿童和青少年的旋回和沟形态计量学发育轨迹

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-24 DOI: 10.1016/j.dcn.2025.101536

Simon R. Poortman , Jakub Jamarík , Louise ten Harmsen van der Beek , Nikita Setiaman , Manon H.J. Hillegers , Marjolein E.A. Barendse , Neeltje E.M. van Haren

{"title":"Developmental trajectories of gyrification and sulcal morphometrics in children and adolescents at high familial risk for bipolar disorder or schizophrenia","authors":"Simon R. Poortman , Jakub Jamarík , Louise ten Harmsen van der Beek , Nikita Setiaman , Manon H.J. Hillegers , Marjolein E.A. Barendse , Neeltje E.M. van Haren","doi":"10.1016/j.dcn.2025.101536","DOIUrl":"10.1016/j.dcn.2025.101536","url":null,"abstract":"<div><div>Offspring of parents with severe mental illness are at increased risk of developing psychopathology. Identifying endophenotypic markers in high-familial-risk individuals can aid in early detection and inform development of prevention strategies. Using generalized additive mixed models, we compared age trajectories of gyrification index (GI) and sulcal morphometric measures (i.e., sulcal depth, length and width) between individuals at familial risk for bipolar disorder or schizophrenia and controls. 300 T1-weighted MRI scans were obtained of 187 individuals (53 % female, age range: 8–23 years) at familial risk for bipolar disorder (n = 80, n families=55) or schizophrenia (n = 53, n families=36) and controls (n = 54, n families=33). 113 individuals underwent two scans. Globally, GI, sulcal depth and sulcal length decreased significantly with age, and sulcal width increased significantly with age in a (near-)linear manner. There were no differences between groups in age trajectories or mean values of gyrification or any of the sulcal measures. These findings suggest that, on average, young individuals at familial risk for bipolar disorder or schizophrenia have preserved developmental patterns of gyrification and sulcal morphometrics during childhood and adolescence.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101536"},"PeriodicalIF":4.6,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Statistical properties of functional connectivity MRI enrichment analysis in school-age autism research 学龄期自闭症研究中功能连接MRI富集分析的统计特性

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-22 DOI: 10.1016/j.dcn.2025.101534

Austin S. Ferguson , Tomoyuki Nishino , Jessica B. Girault , Heather C. Hazlett , Robert T. Schultz , Natasha Marrus , Martin Styner , Santiago Torres-Gomez , Guido Gerig , Alan Evans , Stephen R. Dager , Annette M. Estes , Lonnie Zwaigenbaum , Juhi Pandey , Tanya St. John , Joseph Piven , John R. Pruett Jr. , Alexandre A. Todorov , for the IBIS Network

{"title":"Statistical properties of functional connectivity MRI enrichment analysis in school-age autism research","authors":"Austin S. Ferguson , Tomoyuki Nishino , Jessica B. Girault , Heather C. Hazlett , Robert T. Schultz , Natasha Marrus , Martin Styner , Santiago Torres-Gomez , Guido Gerig , Alan Evans , Stephen R. Dager , Annette M. Estes , Lonnie Zwaigenbaum , Juhi Pandey , Tanya St. John , Joseph Piven , John R. Pruett Jr. , Alexandre A. Todorov , for the IBIS Network","doi":"10.1016/j.dcn.2025.101534","DOIUrl":"10.1016/j.dcn.2025.101534","url":null,"abstract":"<div><div>Mass univariate testing on functional connectivity MRI (fcMRI) data is limited by difficulties achieving experiment-wide significance. Recent work addressing this problem has used enrichment analysis, which aggregates univariate screening statistics for a set of variables into a single enrichment statistic. There have been promising results using this method to explore fcMRI-behavior associations. However, there has not yet been a rigorous examination of the statistical properties of enrichment analysis when applied to fcMRI data. Establishing power for fcMRI enrichment analysis will be important for future neuropsychiatric and cognitive neuroscience study designs that plan to include this method. Here, we use realistic simulation methods, which mimic the covariance structure of fcMRI data, to examine the false positive rate and statistical power of one technique for enrichment analysis, over-representation analysis. We find it can attain high power even for moderate effects and sample sizes, and it strongly outperforms univariate analysis. The false positive rate associated with permutation testing is robust.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101534"},"PeriodicalIF":4.6,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143518924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The overgrowth of structure-function coupling in premature brain during infancy 婴儿期早产儿脑结构-功能耦合过度发育

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-21 DOI: 10.1016/j.dcn.2025.101535

Rong Wang , Tianyu Fang , Yue Zhang , Yue Cheng , Chunfang Wang , Yuanyuan Chen , Qiuyun Fan , Xin Zhao , Dong Ming

{"title":"The overgrowth of structure-function coupling in premature brain during infancy","authors":"Rong Wang , Tianyu Fang , Yue Zhang , Yue Cheng , Chunfang Wang , Yuanyuan Chen , Qiuyun Fan , Xin Zhao , Dong Ming","doi":"10.1016/j.dcn.2025.101535","DOIUrl":"10.1016/j.dcn.2025.101535","url":null,"abstract":"<div><div>Although the rapid growth of brain structure and function during infancy has been well documented, relatively little is known about how these two developmental processes couple—an aspect that exhibits distinct patterns in adult brain. In this study, the multimodal MRI data from the dHCP database were used to investigate the coupling between brain structure and function in infants, with a particular focus on how prematurity influences this relationship. A similar pattern of the coupling distribution between preterm and full-term infants was identified with coupling index varying across unimodal cortices such as visual and sensorimotor regions and transmodal cortices including default mode network. Notably, a widespread overgrowth of structure-function coupling and a slow developmental trajectory towards full-term infants in preterm infants at term-equivalent age were found. Collectively, the study quantified the development of structure-function relationships in preterm infants, offering new insights into the information transmission processes and developmental patterns of the early-life brain.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101535"},"PeriodicalIF":4.6,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143508262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Maternal depressive symptoms in childhood and offspring brain cortical and subcortical volumetric change: A repeated imaging study from age 4–10 years 母亲抑郁症状在儿童和后代大脑皮层和皮层下体积变化：一项4-10岁的重复成像研究

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-14 DOI: 10.1016/j.dcn.2025.101531

Yuna Koyama , Ai Peng Tan , Ekaterina Sadikova , Peipei Setoh , Birit Broekman , Juan Helen Zhou , Peter Gluckman , Helen Chen , Henning Tiemeier

{"title":"Maternal depressive symptoms in childhood and offspring brain cortical and subcortical volumetric change: A repeated imaging study from age 4–10 years","authors":"Yuna Koyama , Ai Peng Tan , Ekaterina Sadikova , Peipei Setoh , Birit Broekman , Juan Helen Zhou , Peter Gluckman , Helen Chen , Henning Tiemeier","doi":"10.1016/j.dcn.2025.101531","DOIUrl":"10.1016/j.dcn.2025.101531","url":null,"abstract":"<div><div>Maternal depressive symptoms have been associated with offspring’s brain structural differences. However, previous studies were limited by cross-sectional designs, brain region-of-interest analyses, or clinical samples. Importantly, few studies assessed the early childhood brain. This study analyzed data from a Singaporean cohort of 217 children with 589 repeated structural neuroimaging from 4.5 to 10.5 years (2–4 assessments) in relation to maternal depressive symptoms. Maternal depressive symptoms were measured by questionnaire at child age 4.5 years. Mixed models explored within-sample change accounting for non-linear brain development. Multiple testing was corrected, and a stringent threshold was applied. Maternal depressive symptoms were associated with persistently smaller precentral gyral volume over time (β = −0.162 [-0.238; −0.086], p<sub>adj</sub> < 0.001). In analysis with time interaction, maternal symptoms were associated with curvilinear changes in the volumes of supramarginal (β = −0.019 [-0.027; −0.010], p<sub>adj</sub> < 0.001) and precuneus gyrus (β = −0.016 [-0.025; −0.007], p<sub>adj</sub> = 0.007); this suggests delayed volumetric development in brain areas governing attention, memory, and language among children exposed to severe maternal symptoms. The findings implicate that childhood maternal depressive symptoms are associated with persistent differences in precentral volume and affect the brain volumetric development of complex sensory information processing regions, rather than in emotion regulation areas implicated in the depression experience. Our findings emphasize repeated childhood imaging to understand child brain development risk factors.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101531"},"PeriodicalIF":4.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143419119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Socioeconomic status and adolescents’ risk-taking behavior: No longitudinal link or differences by neurobiological activation when anticipating social rewards 社会经济地位与青少年冒险行为：当预期社会奖励时，神经生物学激活没有纵向联系或差异

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-14 DOI: 10.1016/j.dcn.2025.101530

Emma Armstrong-Carter , Seh-Joo Kwon , Nathan A. Jorgensen , Mitchell J. Prinstein , Kristen A. Lindquist , Eva H. Telzer

{"title":"Socioeconomic status and adolescents’ risk-taking behavior: No longitudinal link or differences by neurobiological activation when anticipating social rewards","authors":"Emma Armstrong-Carter , Seh-Joo Kwon , Nathan A. Jorgensen , Mitchell J. Prinstein , Kristen A. Lindquist , Eva H. Telzer","doi":"10.1016/j.dcn.2025.101530","DOIUrl":"10.1016/j.dcn.2025.101530","url":null,"abstract":"<div><div>This longitudinal, preregistered study investigated the hypothesis that adolescents who are raised in socioeconomic adversity engage in relatively more health-compromising risk-taking behavior during years when they show relatively heightened anticipation to social rewards. We operationalized this on a neurobiological level as activity of the ventral striatum, a region of the brain that is involved in social reward processing. A sample of 170 racially and socioeconomically diverse adolescents (12<sub>years</sub> at Wave 1, 53 % women, 35 % Latine, 29 % White, 22 % Black) completed annual assessments for up to five years, yielding 478 total observations. During annual fMRI scans, adolescents completed a Social Incentive Delay task during which we measured activation of the ventral striatum in response to anticipating social rewards relative to social punishments. Adolescents also self-reported risk-taking behavior annually, and we linked measures of baseline socioeconomic status via parent report and neighborhood census data. Our preregistered hypotheses were not supported; baseline socioeconomic status was not associated significantly with risk-taking behavior, even during years when adolescents were more attuned to social rewards. Sensitivity analyses examined the role of the anterior insula and amygdala and also yielded null results. Adolescents’ risk-taking behavior may not be as closely linked to socioeconomic status or social reward activation as previously hypothesized.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101530"},"PeriodicalIF":4.6,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The structural covariance of reading-related brain regions in adults and children with typical or poor reading skills 阅读能力一般或较差的成人和儿童阅读相关脑区的结构协方差

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-12 DOI: 10.1016/j.dcn.2025.101522

Amelie Haugg , Nada Frei , Christina Lutz , Sarah V. Di Pietro , Iliana I. Karipidis , Silvia Brem

{"title":"The structural covariance of reading-related brain regions in adults and children with typical or poor reading skills","authors":"Amelie Haugg , Nada Frei , Christina Lutz , Sarah V. Di Pietro , Iliana I. Karipidis , Silvia Brem","doi":"10.1016/j.dcn.2025.101522","DOIUrl":"10.1016/j.dcn.2025.101522","url":null,"abstract":"<div><div>Structural covariance (SC) is a promising approach for studying brain organization in the context of literacy and developmental disorders, offering insights into both structural and functional underpinnings and potential experience-dependent co-development of functional brain networks. Here, we explore the influence of maturation and reading skill on SC in reading-related brain regions. Whole-brain SC analyses were conducted for six key regions of the reading network, including an anterior and posterior subdivision of the visual word form area (VWFA). To study maturational effects, SC was compared between typical-reading adults (N = 134, 25.3 ± 4 yrs) and children (N = 110, 9.6 ± 1.6 yrs). The impact of reading skills on SC was assessed by comparing typical-reading children (N = 110, 9.6 ± 1.6 yrs) to children with poor reading skills (N = 68, 10.2 ± 1.4 yrs). Our results showed significant SC between reading-related brain regions in typical-reading adults. Further, we observed significant SC between the posterior VWFA and the occipital cortex, and between the anterior VWFA and the superior temporal and inferior frontal gyri. There was no indication of a major change in SC within the reading network related to maturation. However, we observed higher SC between the inferior parietal lobule and other reading-related brain regions in children with typical compared to poor reading skills.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101522"},"PeriodicalIF":4.6,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Lifespan trajectories of motor control and neural oscillations: A systematic review of magnetoencephalography insights 运动控制和神经振荡的生命轨迹：脑磁图的系统回顾

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-09 DOI: 10.1016/j.dcn.2025.101529

Xinbi Zhang , Mingming Huang , Xiaoxia Yuan , Xiaoke Zhong , Shengyu Dai , Yingying Wang , Qiang Zhang , Kanya Wongwitwichote , Changhao Jiang

{"title":"Lifespan trajectories of motor control and neural oscillations: A systematic review of magnetoencephalography insights","authors":"Xinbi Zhang , Mingming Huang , Xiaoxia Yuan , Xiaoke Zhong , Shengyu Dai , Yingying Wang , Qiang Zhang , Kanya Wongwitwichote , Changhao Jiang","doi":"10.1016/j.dcn.2025.101529","DOIUrl":"10.1016/j.dcn.2025.101529","url":null,"abstract":"<div><div>Motor control (MC) evolves across the human lifespan, improving during childhood and adolescence, stabilizing in early adulthood, and declining in older age. These developmental and degenerative patterns are linked to neural oscillatory activity, which can be assessed via magnetoencephalography (MEG) to gain insights into motor planning, execution, termination, and command initiation. This review systematically examined age-related changes in MC and neural oscillations, centering on movement-related beta desynchronization (MRBD), post-movement beta rebound (PMBR), and movement-related gamma synchrony (MRGS). Following PRISMA guidelines, 17 cross-sectional studies were identified. The findings revealed significant enhancements in motor efficiency from childhood to adolescence, characterized by faster movement speed, shorter movement duration, weaker MRBD, and increased PMBR and MRGS. From adolescence to early adulthood, further improvements in motor performance were noted, accompanied by strengthened MRBD, PMBR, and a slight decline in MRGS. In older adults, motor performance deteriorates, presenting as slower movement and prolonged duration, alongside heightened resting beta power, elevated MRBD, and reduced PMBR. Alterations in MRGS remain insufficiently explored. Overall, MEG proves valuable for capturing neural dynamics underlying the development and decline of motor control across the lifespan. These findings underscore potential avenues for motor rehabilitation and cognitive interventions, particularly in aging populations.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101529"},"PeriodicalIF":4.6,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infant sleep state coded from respiration and its relationship to the developing functional connectome: A feasibility study 由呼吸编码的婴儿睡眠状态及其与发育中的功能连接体的关系：可行性研究

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-09 DOI: 10.1016/j.dcn.2025.101525

Isabelle Mueller , Raimundo X. Rodriguez , Nicolò Pini , Cristin M. Holland , Rachel Ababio , Sanjana Inala , Kayla Delapenha , Venus Mahmoodi , Milana Khaitova , Xuejun Hao , William P. Fifer , Dustin Scheinost , Marisa N. Spann

{"title":"Infant sleep state coded from respiration and its relationship to the developing functional connectome: A feasibility study","authors":"Isabelle Mueller , Raimundo X. Rodriguez , Nicolò Pini , Cristin M. Holland , Rachel Ababio , Sanjana Inala , Kayla Delapenha , Venus Mahmoodi , Milana Khaitova , Xuejun Hao , William P. Fifer , Dustin Scheinost , Marisa N. Spann","doi":"10.1016/j.dcn.2025.101525","DOIUrl":"10.1016/j.dcn.2025.101525","url":null,"abstract":"<div><div>Most infants are scanned during natural sleep to maximize successful data acquisition by minimizing head and body motion. However, our understanding of how different sleep states affect the infant's functional connectome remains to be determined. In this feasibility study, we develop a novel approach to quantify active and quiet sleep during fMRI using time-locked infant respiration in twenty infants scanned within 47 weeks postmenstrual age. Sleep state (active versus quiet sleep) was then coded using established validated procedures from respiratory variability. Based on this sleep state coding, we investigated differences in the functional connectome comparing active versus quiet sleep. Eleven infants had sufficient quality respiration data to identify sleep states. There were no significant differences in the functional connectome of infants during active and quiet sleep. Still, large effect sizes existed, suggesting that sleep effects may be important in some studies. These findings demonstrate the feasibility and practicality of acquiring respiration data during scanning to facilitate sleep state coding and further understand its relationship to the neurodevelopment of infants. Given the relative ease of collecting respiration data using this setup, we conservatively recommend a wider adoption of our approach.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101525"},"PeriodicalIF":4.6,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0