Developmental Cognitive Neuroscience最新文献

Corrigendum to Developmental changes in dopamine-related neurophysiology and associations with adolescent substance use and incentive-boosted cognitive control. [Dev. Cogn. Neurosci., Vol. 75 (2025): 1-12/101594]. 多巴胺相关神经生理学的发育变化及其与青少年物质使用和激励促进的认知控制的关联。[Dev . Cogn。>。科学通报，Vol. 75(2025): 1-12/101594]。

IF 4.9 2区医学

Developmental Cognitive Neuroscience Pub Date : 2026-05-04 DOI: 10.1016/j.dcn.2026.101734

Jessica S Flannery, Ashley C Parr, Kristen A Lindquist, Eva H Telzer

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Corrigendum to "Brain structures with stronger genetic associations are not less associated with family- and state-level economic contexts" [Dev. Cogn. Neurosci. 70 (2024) 101455]. “具有较强遗传关联的大脑结构与家庭和州一级经济背景的相关性并不低”的勘误表[Dev. Cogn。神经科学学报。70(2024)101455。

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Developmental Cognitive Neuroscience Pub Date : 2026-04-08 DOI: 10.1016/j.dcn.2026.101720

Camille M Williams, David G Weissman, Travis T Mallard, Katie A McLaughlin, K Paige Harden

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The association between longitudinal changes in inter-hemispheric IPS functional connectivity and math gains depends on children’s age and task requirements 半球间IPS功能连接的纵向变化与数学成绩之间的关联取决于儿童的年龄和任务要求

IF 4.9 2区医学

Developmental Cognitive Neuroscience Pub Date : 2026-04-01 Epub Date: 2025-12-30 DOI: 10.1016/j.dcn.2025.101666

Macarena Suárez-Pellicioni , Gavin Price , James R. Booth

{"title":"The association between longitudinal changes in inter-hemispheric IPS functional connectivity and math gains depends on children’s age and task requirements","authors":"Macarena Suárez-Pellicioni , Gavin Price , James R. Booth","doi":"10.1016/j.dcn.2025.101666","DOIUrl":"10.1016/j.dcn.2025.101666","url":null,"abstract":"<div><div>The role of the approximate number system (ANS) in scaffolding symbolic mathematics remains unresolved. A prior neuroimaging study from our group (Suárez-Pellicioni & Booth, 2018) found no significant longitudinal effects of ANS acuity—indexed by intraparietal sulcus (IPS) activation—on gains in math fluency. However, the absence of age-specific analyses and exclusive focus on fluency, which emphasizes retrieval, may have contributed to these null findings. To address these limitations, the present study examined whether age moderates the relationship between inter-hemispheric IPS functional connectivity during a non-symbolic comparison task and math skill. Specifically, we tested: (1) baseline associations at Time 1 (T1); (2) whether T1 connectivity predicts gains in math skill over time (scaffolding hypothesis); and (3) whether changes in connectivity relate to longitudinal gains. Forty-eight children completed a dot comparison task in the scanner at T1 and again two years later. Standardized measures of subtraction skill and math fluency were collected at both time points. We measured general psychophysiological interaction (gPPI) between IPS seeds and contralateral IPS regions. For subtraction skill, we found no evidence of a concurrent association at T1 or predictive effects of T1 connectivity moderated by age. However, changes in connectivity over time revealed an age-dependent pattern: younger children showed gains linked to increased right-left parietal connectivity, while older children showed gains with decreased connectivity. This suggests a developmental shift from effortful integration to more efficient processing. Effects were specific to subtraction, not fluency.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"78 ","pages":"Article 101666"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145898072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Age and gender-related neurophysiological changes in sleep and wake states during childhood 儿童时期睡眠和清醒状态中与年龄和性别相关的神经生理变化

IF 4.9 2区医学

Developmental Cognitive Neuroscience Pub Date : 2026-04-01 Epub Date: 2026-01-21 DOI: 10.1016/j.dcn.2026.101681

Kevin Mammeri , Guillaume Legendre , Fiona Journal , Nathalie Fernandez , Helene Ruppen-Maret , Joanny Combey , Sophie Schwartz , Virginie Sterpenich

{"title":"Age and gender-related neurophysiological changes in sleep and wake states during childhood","authors":"Kevin Mammeri , Guillaume Legendre , Fiona Journal , Nathalie Fernandez , Helene Ruppen-Maret , Joanny Combey , Sophie Schwartz , Virginie Sterpenich","doi":"10.1016/j.dcn.2026.101681","DOIUrl":"10.1016/j.dcn.2026.101681","url":null,"abstract":"<div><div>Brain maturation and sleep patterns evolve throughout childhood, intricately influencing cognitive functions. However, it remains unclear whether changes in sleep and cognition follow similar or distinct trajectories as a function of age and gender during childhood. We included 61 healthy children (30 boys and 31 girls), aged 5–12 years old, who completed a visual memory task and a sustained attention to response task (SART), before and after undergoing one night of polysomnography at home. Our findings revealed large age-related associations in girls, with N3 and REM durations decreasing and sleep spindle frequency during N2 increasing across development. Conversely, these patterns were not observed in boys. Moreover, a significant interaction showed a shift in delta power topography from posterior to anterior regions in girls compared to boys. Alongside these sleep changes, girls exhibited a predominant excitatory pattern of brain activity during wakefulness as evidenced by a reduction in resting EEG slope. Regarding cognition, we found a large correlation between the increase in sleep spindle frequency in girls and morning accuracy on the SART. Overnight memory consolidation did not vary with age or gender. Taken together, these findings suggest an earlier onset of brain maturation in girls, reflected by less deep sleep, faster sleep spindles, frontal shift in delta power, and greater cortical excitability during wakefulness. This pattern in girls challenges the notion that developmental modifications of sleep are minimal during childhood. How closely may these changes relate to puberty or timing remain to be established in future longitudinal studies.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"78 ","pages":"Article 101681"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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An automated pipeline for efficiently generating standardized, child-friendly audiovisual language stimuli 一个自动化的管道，有效地产生标准化，儿童友好的视听语言刺激

IF 4.9 2区医学

Developmental Cognitive Neuroscience Pub Date : 2026-04-01 Epub Date: 2026-01-13 DOI: 10.1016/j.dcn.2026.101674

Bianca Santi , Matthew Soza , Greta Tuckute , Aalok Sathe , Evelina Fedorenko , Halie Olson

{"title":"An automated pipeline for efficiently generating standardized, child-friendly audiovisual language stimuli","authors":"Bianca Santi , Matthew Soza , Greta Tuckute , Aalok Sathe , Evelina Fedorenko , Halie Olson","doi":"10.1016/j.dcn.2026.101674","DOIUrl":"10.1016/j.dcn.2026.101674","url":null,"abstract":"<div><div>Creating engaging language stimuli suitable for children can be difficult and time-consuming. To simplify and accelerate the process, we developed an automated pipeline that combines existing audio generation and animation tools to generate customizable audiovisual stimuli from text input. The pipeline consists of two components: the first uses Google Cloud Text-to-Speech to generate audio stimuli from text, and the second uses Adobe Character Animator to create video stimuli in which an animated character “speaks” the audio with speech-aligned mouth movements. We evaluated the pipeline with two stimulus sets, including an acoustic comparison between generated audio stimuli and existing human-recorded stimuli. The pipeline is efficient, taking less than 2 min to generate each audiovisual stimulus, and fewer than 9 % of stimuli needed to be regenerated. The audio generation component is particularly fast, taking less than 1 s per stimulus. By leveraging automated tools for language stimulus creation, this pipeline can facilitate developmental research on language and other domains of cognition, especially in cognitive neuroscience studies that require large numbers of stimuli.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"78 ","pages":"Article 101674"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145979538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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From Breath to Brain: NICU respiratory interventions and bedside brain signal entropy predict later autism risk 从呼吸到大脑：新生儿重症监护室呼吸干预和床边脑信号熵预测后期自闭症风险

IF 4.9 2区医学

Developmental Cognitive Neuroscience Pub Date : 2026-04-01 Epub Date: 2026-01-16 DOI: 10.1016/j.dcn.2026.101679

Madelyn G. Nance , Winnie R. Chang , Chad Aldridge , Jennifer Burnsed , Kevin Pelphrey , Santina Zanelli , Meghan H. Puglia

{"title":"From Breath to Brain: NICU respiratory interventions and bedside brain signal entropy predict later autism risk","authors":"Madelyn G. Nance , Winnie R. Chang , Chad Aldridge , Jennifer Burnsed , Kevin Pelphrey , Santina Zanelli , Meghan H. Puglia","doi":"10.1016/j.dcn.2026.101679","DOIUrl":"10.1016/j.dcn.2026.101679","url":null,"abstract":"<div><div>Premature infants often experience hypoxia and require prolonged ventilation, which can trigger systemic inflammation, damage the developing brain, and increase the risk of neurodevelopmental disorders such as Autism Spectrum Disorder (ASD). Early intervention is key for ensuring optimal outcomes for those with ASD; thus emphasizing the critical importance of accurately identifying infants at risk as early as possible. Here, infants underwent electroencephalography during social (held) and nonsocial (not held) resting state conditions to assess brain signal variability, saliva collection to determine inflammation, calculation of a novel Prognostic Respiratory Intensity Scoring Metric (PRISM) to assess the burden of respiratory support, and ASD testing in toddlerhood. Higher PRISM scores were associated with increased brain signal entropy during the nonsocial resting state. However, this association was not observed in the social resting state condition – particularly for male babies. Interestingly in female infants, we saw that the relationship between brain signal entropy and PRISM scores were potentially mediated by cytokines. Notably, the interaction between nonsocial resting state brain signal entropy, sex, and PRISM scores predicted risk of developing ASD with 88 % accuracy. These non-invasive measures can identify infants at the highest risk for an ASD diagnosis before discharge.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"78 ","pages":"Article 101679"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Associations between prenatal paracetamol exposure and brain development from ages 4–16: A longitudinal MRI study 产前扑热息痛暴露与4-16岁大脑发育之间的关系：一项纵向MRI研究

IF 4.9 2区医学

Developmental Cognitive Neuroscience Pub Date : 2026-04-01 Epub Date: 2025-12-30 DOI: 10.1016/j.dcn.2025.101667

Stine Kleppe Krogsrud , Hedvig Nordeng , James M. Roe , Janne von Koss Torkildsen , Mollie E. Wood , Eivind Ystrom

{"title":"Associations between prenatal paracetamol exposure and brain development from ages 4–16: A longitudinal MRI study","authors":"Stine Kleppe Krogsrud , Hedvig Nordeng , James M. Roe , Janne von Koss Torkildsen , Mollie E. Wood , Eivind Ystrom","doi":"10.1016/j.dcn.2025.101667","DOIUrl":"10.1016/j.dcn.2025.101667","url":null,"abstract":"<div><div>Research has raised concerns regarding the potential impact of prenatal paracetamol exposure on fetal neurodevelopment. This is the first longitudinal study to investigate whether such exposure is related to structural brain development and cognitive abilities during childhood and adolescence. The sample includes 447 children aged 4.1–16.2 years with 905 MRI scans. The study is based on The Norwegian Mother, Father and Child Study (MoBa), and uses data from the Medical Birth Registry of Norway. The exposure variable is mothers’ self-reported use of paracetamol from prenatal and postnatal questionnaires. Among 447 children (229 girls; mean age 8.38 years), 193 (43.2 %) were prenatally exposed. Days of exposure range from 1 to 128 (mean 8.2). Vertex-wise linear mixed effect models showed that exposed children (n = 193; 393 scans) had slightly smaller cortical surface area and volume in some regions compared to non-exposed children. These results were seemingly driven by long-term exposed children (≥14 days <em>in utero</em>; n = 35; 72 scans, and exposed in all three trimesters, n = 21; 44 scans). However, group differences in brain structure were small with largely overlapping distributions, and the observational design and risk of unmeasured confounding preclude causal inference. Thus, the clinical significance remains uncertain. For cognitive abilities, results were reassuring showing no significant effect of prenatal paracetamol exposure on working memory capacity or IQ scores.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"78 ","pages":"Article 101667"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145898073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Dimensional adversity, brain-age, & mental health: Differences in male and female adolescents 维度逆境、脑年龄和心理健康：男女青少年的差异。

IF 4.9 2区医学

Developmental Cognitive Neuroscience Pub Date : 2026-04-01 Epub Date: 2026-01-13 DOI: 10.1016/j.dcn.2026.101671

Michelle Shaul , Sarah Whittle , Niousha Dehestani , Timothy J. Silk , Nandita Vijayakumar

{"title":"Dimensional adversity, brain-age, & mental health: Differences in male and female adolescents","authors":"Michelle Shaul , Sarah Whittle , Niousha Dehestani , Timothy J. Silk , Nandita Vijayakumar","doi":"10.1016/j.dcn.2026.101671","DOIUrl":"10.1016/j.dcn.2026.101671","url":null,"abstract":"<div><div>Early life adversity (ELA) has been linked to shifts in developmental pace. This study examined whether brain maturity during early adolescence was influenced by ELA, and whether it explained the relationship between ELA and mental health problems. A sample (<em>n</em> = 7658, 46 % female) from the Adolescent Brain and Cognitive Development (ABCD) Study was utilized, with data collected at three time points spanning 9–14 years of age. Exposure to threat, psychosocial deprivation, household instability, and socioeconomic stress were measured at baseline. A predictive model of normative brain development (brain age) trained on a large independent lifespan sample was applied to structural neuroimaging data from the second timepoint. Brain-age-gap (BAG) – the difference between model predicted brain age and chronological age – was tested as a mediator of adversity exposure and internalizing/externalizing problems at the third timepoint. A more positive BAG was associated with more externalizing problems, but hypothesized associations between adversity and BAG were not significant. Sex moderation of these pathways suggests adversity may differentially affect the pace of brain development for males and females, which uniquely explains vulnerability to externalizing problems. The findings highlight the importance of examining sex-specific effects of adversity on adolescent development and mental health.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"78 ","pages":"Article 101671"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146012475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Neurodevelopmental correlates of emotion regulation in adolescence: An accelerated longitudinal study 青少年情绪调节的神经发育相关性：一项加速的纵向研究

IF 4.9 2区医学

Developmental Cognitive Neuroscience Pub Date : 2026-04-01 Epub Date: 2025-12-23 DOI: 10.1016/j.dcn.2025.101664

Galit Karpov , Sara A. Heyn , Justin D. Russell , Taylor J. Keding , Ryan J. Herringa

{"title":"Neurodevelopmental correlates of emotion regulation in adolescence: An accelerated longitudinal study","authors":"Galit Karpov , Sara A. Heyn , Justin D. Russell , Taylor J. Keding , Ryan J. Herringa","doi":"10.1016/j.dcn.2025.101664","DOIUrl":"10.1016/j.dcn.2025.101664","url":null,"abstract":"<div><h3>Background</h3><div>Adolescence is a period that coincides with a peak in both the onset of psychopathology and a sensitive period for neural development. One transdiagnostic characteristic of psychopathology is impaired emotion regulation (ER), a process with both implicit (automatic) and explicit (voluntary) underpinnings. The current study aims to better understand the normative neurodevelopment of these two components of ER in adolescents.</div></div><div><h3>Methods</h3><div>139 youth (aged 10–20 years) completed ER assessment during fMRI at baseline and one-year follow-up. Implicit and explicit ER were examined using an emotional N-Back and a cognitive reappraisal task, respectively. Linear-mixed effects modeling was used to identify regions of the frontal cortex (Schaefer atlas) and the amygdala and hippocampus (Tian atlas) whose activity was predicted by ER- and age-related variables, covaried for sex, childhood adversity, and psychopathology symptoms.</div></div><div><h3>Results</h3><div>Regions that displayed change across age were localized to the salience/ventral attention network in the right hemisphere. For implicit ER, mid-insula activity showed changes during early adolescence (∼10 years old), such that activity to negative stimuli increased during this time before plateauing. For explicit ER, the posterior insula, Rolandic Operculum, and paracentral lobule showed linear decreases in activity across the entire age range, where the decrease occurred at a faster rate in response to neutral relative to negative stimuli.</div></div><div><h3>Conclusions</h3><div>Functional changes in frontal circuits related to emotional attention may encode the development of ER during neurodevelopment. Maturation of these circuits seem to reach completion by mid-adolescence for implicit ER, but explicit ER continues developing across adolescence.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"78 ","pages":"Article 101664"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145898053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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The impact of a monthly unconditional cash transfer on child brain activity: A 4-year follow-up 每月无条件现金转移对儿童大脑活动的影响：4年随访

IF 4.9 2区医学

Developmental Cognitive Neuroscience Pub Date : 2026-04-01 Epub Date: 2026-01-14 DOI: 10.1016/j.dcn.2026.101673

Sonya V. Troller-Renfree , Molly A. Costanzo , Greg J. Duncan , Katherine Magnuson , Lisa A. Gennetian , Hirokazu Yoshikawa , Sarah R. Black , Debra S. Karhson , Michael K. Georgieff , Jennifer Mize Nelson , Timothy D. Nelson , Nathan A. Fox , Kimberly G. Noble

{"title":"The impact of a monthly unconditional cash transfer on child brain activity: A 4-year follow-up","authors":"Sonya V. Troller-Renfree , Molly A. Costanzo , Greg J. Duncan , Katherine Magnuson , Lisa A. Gennetian , Hirokazu Yoshikawa , Sarah R. Black , Debra S. Karhson , Michael K. Georgieff , Jennifer Mize Nelson , Timothy D. Nelson , Nathan A. Fox , Kimberly G. Noble","doi":"10.1016/j.dcn.2026.101673","DOIUrl":"10.1016/j.dcn.2026.101673","url":null,"abstract":"<div><div>Early childhood poverty is associated with neurodevelopmental differences, but causal evidence linking income to brain development is sparse. In the present study, we examine whether four years of monthly unconditional cash transfers to mothers experiencing low income cause differences in their preschoolers’ brain activity. Shortly after giving birth, mothers were randomized to receive $333/month or $20/month for the first several years of their child’s life as a part of the Baby’s First Years study. Here we report on the impact of these cash gifts on resting brain electric activity recorded at 4 years of age as measured by electroencephalography (EEG). We find no impact on our primary preregistered outcome (an aggregated index of mid-to-high-frequency brain activity) or our secondary preregistered outcome frontal gamma power. We did find, in additional exploratory analyses that were part of our pre-registered analytic plan, that preschoolers in the high-cash gift group had higher alpha power compared to those in the low-cash gift group. There were no differences in theta, beta, or gamma power between groups. Although the primary and secondary preregistered outcomes showed no group differences our exploratory analyses provide some evidence for impacts on children’s alpha power during the preschool years, although this evidence needs further investigation and replication.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"78 ","pages":"Article 101673"},"PeriodicalIF":4.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146038498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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