Developmental Cognitive Neuroscience最新文献_第2页

Lifespan trajectories of motor control and neural oscillations: A systematic review of magnetoencephalography insights

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-09 DOI: 10.1016/j.dcn.2025.101529

Xinbi Zhang , Mingming Huang , Xiaoxia Yuan , Xiaoke Zhong , Shengyu Dai , Yingying Wang , Qiang Zhang , Kanya Wongwitwichote , Changhao Jiang

{"title":"Lifespan trajectories of motor control and neural oscillations: A systematic review of magnetoencephalography insights","authors":"Xinbi Zhang , Mingming Huang , Xiaoxia Yuan , Xiaoke Zhong , Shengyu Dai , Yingying Wang , Qiang Zhang , Kanya Wongwitwichote , Changhao Jiang","doi":"10.1016/j.dcn.2025.101529","DOIUrl":"10.1016/j.dcn.2025.101529","url":null,"abstract":"<div><div>Motor control (MC) evolves across the human lifespan, improving during childhood and adolescence, stabilizing in early adulthood, and declining in older age. These developmental and degenerative patterns are linked to neural oscillatory activity, which can be assessed via magnetoencephalography (MEG) to gain insights into motor planning, execution, termination, and command initiation. This review systematically examined age-related changes in MC and neural oscillations, centering on movement-related beta desynchronization (MRBD), post-movement beta rebound (PMBR), and movement-related gamma synchrony (MRGS). Following PRISMA guidelines, 17 cross-sectional studies were identified. The findings revealed significant enhancements in motor efficiency from childhood to adolescence, characterized by faster movement speed, shorter movement duration, weaker MRBD, and increased PMBR and MRGS. From adolescence to early adulthood, further improvements in motor performance were noted, accompanied by strengthened MRBD, PMBR, and a slight decline in MRGS. In older adults, motor performance deteriorates, presenting as slower movement and prolonged duration, alongside heightened resting beta power, elevated MRBD, and reduced PMBR. Alterations in MRGS remain insufficiently explored. Overall, MEG proves valuable for capturing neural dynamics underlying the development and decline of motor control across the lifespan. These findings underscore potential avenues for motor rehabilitation and cognitive interventions, particularly in aging populations.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101529"},"PeriodicalIF":4.6,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infant sleep state coded from respiration and its relationship to the developing functional connectome: A feasibility study

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-09 DOI: 10.1016/j.dcn.2025.101525

Isabelle Mueller , Raimundo X. Rodriguez , Nicolò Pini , Cristin M. Holland , Rachel Ababio , Sanjana Inala , Kayla Delapenha , Venus Mahmoodi , Milana Khaitova , Xuejun Hao , William P. Fifer , Dustin Scheinost , Marisa N. Spann

{"title":"Infant sleep state coded from respiration and its relationship to the developing functional connectome: A feasibility study","authors":"Isabelle Mueller , Raimundo X. Rodriguez , Nicolò Pini , Cristin M. Holland , Rachel Ababio , Sanjana Inala , Kayla Delapenha , Venus Mahmoodi , Milana Khaitova , Xuejun Hao , William P. Fifer , Dustin Scheinost , Marisa N. Spann","doi":"10.1016/j.dcn.2025.101525","DOIUrl":"10.1016/j.dcn.2025.101525","url":null,"abstract":"<div><div>Most infants are scanned during natural sleep to maximize successful data acquisition by minimizing head and body motion. However, our understanding of how different sleep states affect the infant's functional connectome remains to be determined. In this feasibility study, we develop a novel approach to quantify active and quiet sleep during fMRI using time-locked infant respiration in twenty infants scanned within 47 weeks postmenstrual age. Sleep state (active versus quiet sleep) was then coded using established validated procedures from respiratory variability. Based on this sleep state coding, we investigated differences in the functional connectome comparing active versus quiet sleep. Eleven infants had sufficient quality respiration data to identify sleep states. There were no significant differences in the functional connectome of infants during active and quiet sleep. Still, large effect sizes existed, suggesting that sleep effects may be important in some studies. These findings demonstrate the feasibility and practicality of acquiring respiration data during scanning to facilitate sleep state coding and further understand its relationship to the neurodevelopment of infants. Given the relative ease of collecting respiration data using this setup, we conservatively recommend a wider adoption of our approach.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101525"},"PeriodicalIF":4.6,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Longitudinal analysis of the ABCD® study

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-08 DOI: 10.1016/j.dcn.2025.101518

Samuel W. Hawes , Andrew K. Littlefield , Daniel A. Lopez , Kenneth J. Sher , Erin L. Thompson , Raul Gonzalez , Laika Aguinaldo , Ashley R. Adams , Mohammadreza Bayat , Amy L. Byrd , Luis FS Castro-de-Araujo , Anthony Dick , Steven F. Heeringa , Christine M. Kaiver , Sarah M. Lehman , Lin Li , Janosch Linkersdörfer , Thomas J. Maullin-Sapey , Michael C. Neale , Thomas E. Nichols , Wesley K. Thompson

{"title":"Longitudinal analysis of the ABCD® study","authors":"Samuel W. Hawes , Andrew K. Littlefield , Daniel A. Lopez , Kenneth J. Sher , Erin L. Thompson , Raul Gonzalez , Laika Aguinaldo , Ashley R. Adams , Mohammadreza Bayat , Amy L. Byrd , Luis FS Castro-de-Araujo , Anthony Dick , Steven F. Heeringa , Christine M. Kaiver , Sarah M. Lehman , Lin Li , Janosch Linkersdörfer , Thomas J. Maullin-Sapey , Michael C. Neale , Thomas E. Nichols , Wesley K. Thompson","doi":"10.1016/j.dcn.2025.101518","DOIUrl":"10.1016/j.dcn.2025.101518","url":null,"abstract":"<div><div>The Adolescent Brain Cognitive Development® (ABCD) Study provides a unique opportunity to investigate developmental processes in a large, diverse cohort of youths, aged approximately 9–10 at baseline and assessed annually for 10 years. Given the size and complexity of the ABCD Study, researchers analyzing its data will encounter a myriad of methodological and analytical considerations. This review provides an examination of key concepts and techniques related to longitudinal analyses of the ABCD Study data, including: (1) characterization of the factors associated with variation in developmental trajectories; (2) assessment of how level and timing of exposures may impact subsequent development; (3) quantification of how variation in developmental domains may be associated with outcomes, including mediation models and reciprocal relationships. We emphasize the importance of selecting appropriate statistical models to address these research questions. By presenting the advantages and potential challenges of longitudinal analyses in the ABCD Study, this review seeks to equip researchers with foundational knowledge and tools to make informed decisions as they navigate and effectively analyze and interpret the multi-dimensional longitudinal data currently available.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101518"},"PeriodicalIF":4.6,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143474956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A longitudinal neuroimaging study of adolescent girls’ mentalizing and perspective-taking tendencies

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-07 DOI: 10.1016/j.dcn.2025.101526

Victoria Guazzelli Williamson , Marjolein E.A. Barendse , Samantha J. Chavez , John C. Flournoy , Theresa W. Cheng , Danielle Cosme , Michelle L. Byrne , Nicholas B. Allen , Jennifer H. Pfeifer

{"title":"A longitudinal neuroimaging study of adolescent girls’ mentalizing and perspective-taking tendencies","authors":"Victoria Guazzelli Williamson , Marjolein E.A. Barendse , Samantha J. Chavez , John C. Flournoy , Theresa W. Cheng , Danielle Cosme , Michelle L. Byrne , Nicholas B. Allen , Jennifer H. Pfeifer","doi":"10.1016/j.dcn.2025.101526","DOIUrl":"10.1016/j.dcn.2025.101526","url":null,"abstract":"<div><div>Research in developmental psychology suggests that self-concept formation and mentalizing capacities, along with their neural foundations, show significant developmental change during adolescence. Perspective-taking tendencies are also believed to increase in adolescence, supporting the refinement of prosocial behavior and the demands of increasingly complex social relationships. To explore the development of, and relationship between, these processes in adolescence, early adolescent girls (N = 172) completed a measure of perspective-taking tendencies and a self-evaluation fMRI task at two waves, approximately 18 months apart (mean ages = 11.62 and 13.20, respectively). In line with our hypothesis, perspective-taking tendencies were positively associated with age. Greater perspective-taking tendencies were also associated with a more prosocial, and less antisocial, self-concept. In addition, dmPFC activity increased with age, but this did not survive correction for multiple comparisons across all mentalizing regions. Post hoc analyses also showed that an increase in perspective-taking tendencies across waves was significantly associated with activity in parts of the precuneus at wave 2. Finally, while we did not observe cross-variable coupling, our Bivariate Latent Change Score model showed that lower perspective-taking tendencies at wave 1 were associated with greater latent change in this variable (and the same was true for mean activity in mentalizing brain regions).</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101526"},"PeriodicalIF":4.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143454717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A light in the darkness: Early phases of development and the emergence of cognition

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-07 DOI: 10.1016/j.dcn.2025.101527

Elisa Cainelli , Giulia Stramucci , Patrizia Bisiacchi

{"title":"A light in the darkness: Early phases of development and the emergence of cognition","authors":"Elisa Cainelli , Giulia Stramucci , Patrizia Bisiacchi","doi":"10.1016/j.dcn.2025.101527","DOIUrl":"10.1016/j.dcn.2025.101527","url":null,"abstract":"<div><div>During the prenatal period, the major brain development milestones are posed and calibrated through different mechanisms, among which endogenous activity, that prepares the \"system\" to face the external environment. However, the specific nature of the human nervous system, intended for brain plasticity that is varied by brain area and prolonged over time, requires much time for environmental experiences to shape the cerebral circuitries. Therefore, the neonate completely depends on the caregiver, and during the first months of postnatal life, it exhibits a transitory and limited repertoire of behaviors and skills that favors the mother in her new role. This transitory condition will gradually give way to more mature competencies, the milestones of which are posed within 2 years of age. This review takes a new perspective on early development and attempts to trace the remarkable changes from <em>in-utero</em> period to the second year of postnatal life, posing a bridge between the neurobiological substrate and behavioral development. We based our work on the \"normal\" development, pointing out the risks inherent in any development process.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101527"},"PeriodicalIF":4.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143379411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dev-Atlas: A reference atlas of functional brain networks for typically developing adolescents

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-07 DOI: 10.1016/j.dcn.2025.101523

Gaelle E. Doucet , Callum Goldsmith , Katrina Myers , Danielle L. Rice , Grace Ende , Derek J. Pavelka , Marc Joliot , Vince D. Calhoun , Tony W. Wilson , Lucina Q. Uddin

{"title":"Dev-Atlas: A reference atlas of functional brain networks for typically developing adolescents","authors":"Gaelle E. Doucet , Callum Goldsmith , Katrina Myers , Danielle L. Rice , Grace Ende , Derek J. Pavelka , Marc Joliot , Vince D. Calhoun , Tony W. Wilson , Lucina Q. Uddin","doi":"10.1016/j.dcn.2025.101523","DOIUrl":"10.1016/j.dcn.2025.101523","url":null,"abstract":"<div><div>It is well accepted that the brain is functionally organized into multiple networks and extensive literature has demonstrated that the organization of these networks shows major changes during adolescence. Yet, there is limited option for a reference functional brain atlas derived from typically-developing adolescents, which is problematic as the reliable identification of functional brain networks crucially depends on the use of such reference functional atlases. In this context, we utilized resting-state functional MRI data from 1391 typically-developing youth aged 8–17 years to create an adolescent-specific reference atlas of functional brain networks. We further investigated the impact of age and sex on these networks. Using a multiscale individual component clustering algorithm, we identified 24 reliable functional brain networks, classified within six domains: Default-Mode (5 networks), Control (4 networks), Salience (3 networks), Attention (4 networks), Somatomotor (5 networks), and Visual (3 networks). We identified reliable and large effects of age on the spatial topography of these majority of networks, as well as on the functional network connectivity. Sex effects were not as widespread. We created a novel brain atlas, named Dev-Atlas, focused on a typically-developing sample, with the hope that this atlas can be used in future developmental neuroscience studies.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101523"},"PeriodicalIF":4.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143387621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Infant attention and frontal EEG neuromarkers of childhood ADHD

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-07 DOI: 10.1016/j.dcn.2025.101524

Cassondra M. Eng , Leslie A. Patton , Martha Ann Bell

{"title":"Infant attention and frontal EEG neuromarkers of childhood ADHD","authors":"Cassondra M. Eng , Leslie A. Patton , Martha Ann Bell","doi":"10.1016/j.dcn.2025.101524","DOIUrl":"10.1016/j.dcn.2025.101524","url":null,"abstract":"<div><div>Numerous electroencephalogram (EEG) studies have sought to elucidate the neural mechanisms of attention deficit hyperactivity disorder (ADHD), with most of the existing literature focused on children, adolescents, and adults. In this retrospective study, measures of frontal EEG power and behavioral attention of 40 5-month-old infants later diagnosed with ADHD in childhood were compared to 40 systematically matched-control infants. Compared to the control group, infants in the ADHD group exhibited longer looking fixations during an attention task. Frontal EEG power in the 6–9 Hz infant alpha band was lower in the ADHD group compared to the control group. Mean frontal EEG power was associated with visual fixations, underscoring specific attention behavior corresponding to frontal brain development in infancy. Infants later diagnosed with ADHD exhibited higher attention problems in childhood at ages 4 and 9 compared to the control group, and longer looking fixations in infancy were associated with higher childhood ADHD-related symptomatology. These findings suggest that decreased infant frontal EEG power and looking fixations as early as 5-months of age may serve as important early markers of later ADHD and can aid in building a more comprehensive model of ADHD from a developmental neuroscience approach.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101524"},"PeriodicalIF":4.6,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143444533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Common and unique network basis for externally and internally driven flexibility in cognition: From a developmental perspective

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-02-06 DOI: 10.1016/j.dcn.2025.101528

Ziyi Huang , Dazhi Yin

{"title":"Common and unique network basis for externally and internally driven flexibility in cognition: From a developmental perspective","authors":"Ziyi Huang , Dazhi Yin","doi":"10.1016/j.dcn.2025.101528","DOIUrl":"10.1016/j.dcn.2025.101528","url":null,"abstract":"<div><div>Flexibility is a hallmark of cognitive control and can be driven externally and internally, corresponding to reactive and spontaneous flexibility. However, the convergence and divergence between these two types of flexibility and their underlying neural basis during development remain largely unknown. In this study, we aimed to determine the common and unique networks for reactive and spontaneous flexibility as a function of age and sex, leveraging both cross-sectional and longitudinal resting-state functional magnetic resonance imaging datasets with different temporal resolutions (N = 249, 6–35 years old). Functional connectivity strength and nodal flexibility, derived from static and dynamic frameworks respectively, were utilized. We found similar quadratic effects of age on reactive and spontaneous flexibility, which were mediated by the functional connectivity strength and nodal flexibility of the frontoparietal network. Divergence was observed, with the nodal flexibility of the ventral attention network at the baseline visit uniquely predicting the increase in reactive flexibility 24–30 months later, while the nodal flexibility or functional connectivity strength of the dorsal attention network could specifically predict the increase in spontaneous flexibility. Sex differences were found in tasks measuring reactive and spontaneous flexibility simultaneously, which were moderated by the nodal flexibility of the dorsal attention network. This study advances our understanding of distinct types of flexibility in cognition and their underlying mechanisms throughout developmental stages. Our findings also suggest the importance of studying specific types of cognitive flexibility abnormalities in developmental neuropsychiatric disorders.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101528"},"PeriodicalIF":4.6,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metacontrol instructions lead to adult-like event segmentation in adolescents 元控制指令会使青少年产生类似成人的事件分割能力。

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-01-30 DOI: 10.1016/j.dcn.2025.101521

Xianzhen Zhou , Foroogh Ghorbani , Veit Roessner , Bernhard Hommel , Astrid Prochnow , Christian Beste

{"title":"Metacontrol instructions lead to adult-like event segmentation in adolescents","authors":"Xianzhen Zhou , Foroogh Ghorbani , Veit Roessner , Bernhard Hommel , Astrid Prochnow , Christian Beste","doi":"10.1016/j.dcn.2025.101521","DOIUrl":"10.1016/j.dcn.2025.101521","url":null,"abstract":"<div><div>Event segmentation, which involves dividing continuous information into meaningful units, changes as children develop into adolescents. Adolescents tend to segment events more coarsely than adults. This study explores whether adolescents could adjust their segmentation style to resemble that of adults when provided with explicit metacontrol-related instructions. We compared event segmentation in two adolescent groups and one adult group, while simultaneously recording EEG data. One adolescent group was instructed to perform segmentation as finely as possible, whereas the other adolescent group and adults received no specific instructions on segmentation granularity. EEG data were analyzed using multivariate pattern analysis and source reconstruction. The findings revealed that adolescents given fine-grained instructions adjusted their segmentation probability closer to adult levels, although they did not fully match adults in processing multiple simultaneous changes. Neurophysiological results indicated that adolescents with fine-grained instructions exhibited neural decoding performance more similar to adults. Increased activity in the inferior frontal gyrus in these adolescents compared to adults related to this. The results suggest that adolescents with fine-grained instructions demonstrated more persistent cognitive control and enhanced top-down attention than their peers and adults. The study shows that adolescent cognitive processes can be shifted toward adult-like performance through instructions.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101521"},"PeriodicalIF":4.6,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond motor learning: Insights from infant magnetic resonance imaging on the critical role of the cerebellum in behavioral development

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2025-01-27 DOI: 10.1016/j.dcn.2025.101514

Lauren Wagner , Melis E Cakar , Megan Banchik , Emily Chiem , Siobhan Sive Glynn , Amy H Than , Shulamite A Green , Mirella Dapretto

{"title":"Beyond motor learning: Insights from infant magnetic resonance imaging on the critical role of the cerebellum in behavioral development","authors":"Lauren Wagner , Melis E Cakar , Megan Banchik , Emily Chiem , Siobhan Sive Glynn , Amy H Than , Shulamite A Green , Mirella Dapretto","doi":"10.1016/j.dcn.2025.101514","DOIUrl":"10.1016/j.dcn.2025.101514","url":null,"abstract":"<div><div>Although the cerebellum is now recognized for its crucial role in non-motor functions such as language, perceptual processes, social communication, and executive function in adults, it is often overlooked in studies of non-motor behavioral development in infancy. Recent magnetic resonance imaging (MRI) research increasingly shows the cerebellum is key to understanding the emergence of complex human behaviors and neurodevelopmental conditions. This review summarizes studies from diverse MRI modalities that link early cerebellar development from birth to age two with emerging non-motor behaviors and psychiatric symptomatology. Our focus centered on both term and preterm infants, excluding studies of perinatal injury and cerebellar pathology. We conclude that the cerebellum is implicated in many non-motor behaviors and implicit learning mechanisms in infancy. The field’s current limitations include inconsistencies in study design, a paucity of gold-standard infant neuroimaging tools, and treatment of the cerebellum as a uniform structure. Moving forward, the cerebellum should be considered a structure of greater interest to the developmental neuroimaging community. Studies should test developmental hypotheses about the behavioral roles of specific cerebro-cerebellar circuits, and theoretical frameworks such as Olson’s “model switch” hypothesis of cerebellar learning. Large-scale, longitudinal, well-powered neuroimaging studies of typical and preterm development will be key.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"72 ","pages":"Article 101514"},"PeriodicalIF":4.6,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143225978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0