Developmental Cognitive Neuroscience最新文献

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The connecting brain in context: How adolescent plasticity supports learning and development. 情境中的连接大脑:青少年可塑性如何支持学习和发展。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2024-11-28 DOI: 10.1016/j.dcn.2024.101486
Amanda E Baker, Adriana Galván, Andrew J Fuligni
{"title":"The connecting brain in context: How adolescent plasticity supports learning and development.","authors":"Amanda E Baker, Adriana Galván, Andrew J Fuligni","doi":"10.1016/j.dcn.2024.101486","DOIUrl":"10.1016/j.dcn.2024.101486","url":null,"abstract":"<p><p>Puberty initiates significant neurobiological changes that amplify adolescents' responsiveness to their environment, facilitating neural adaptation through processes like synaptic pruning, myelination, and neuronal reorganization. This heightened neuroplasticity, combined with their burgeoning social curiosity and appetite for risk, propels adolescents to explore diverse new environments and forge social bonds. Such exploration can accelerate experiential learning and the formation of social networks as adolescents prepare for adult independence. This review examines the complex interplay between adolescent neuroplasticity, environmental influences, and learning processes, synthesizing findings from recent studies that illustrate how factors such as social interactions, school environments, and neighborhood contexts influence both the transient activation and enduring organization of the developing brain. We advocate for incorporating social interaction into adolescent-tailored interventions, leveraging their social plasticity to optimize learning and development during this critical phase. Going forward, we discuss the importance of longitudinal studies that employ multimodal approaches to characterize the dynamic interactions between development and environment, highlighting recent advancements in quantifying environmental impacts in studies of developmental neuroscience. Ultimately, this paper provides an updated synopsis of adolescent neuroplasticity and the environment, underscoring the potential for environmental enrichment programs to support healthy brain development and resilience at this critical development stage.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101486"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Harmonizing multisite neonatal diffusion-weighted brain MRI data for developmental neuroscience. 协调多位点新生儿弥散加权脑MRI数据用于发育神经科学。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2024-12-08 DOI: 10.1016/j.dcn.2024.101488
Alexandra F Bonthrone, Manuel Blesa Cábez, A David Edwards, Jo V Hajnal, Serena J Counsell, James P Boardman
{"title":"Harmonizing multisite neonatal diffusion-weighted brain MRI data for developmental neuroscience.","authors":"Alexandra F Bonthrone, Manuel Blesa Cábez, A David Edwards, Jo V Hajnal, Serena J Counsell, James P Boardman","doi":"10.1016/j.dcn.2024.101488","DOIUrl":"10.1016/j.dcn.2024.101488","url":null,"abstract":"<p><p>Large diffusion-weighted brain MRI (dMRI) studies in neonates are crucial for developmental neuroscience. Our aim was to investigate the utility of ComBat, an empirical Bayes tool for multisite harmonization, in removing site effects from white matter (WM) dMRI measures in healthy infants born at 37 gestational weeks+ 0 days-42 weeks+ 6 days from the Theirworld Edinburgh Birth Cohort (n = 86) and Developing Human Connectome Project (n = 287). Skeletonized fractional anisotropy (FA), mean, axial and radial diffusivity (MD, AD, RD) maps were harmonized. Differences between voxel-wise metrics, skeleton means and histogram widths (5th-95th percentile) were assessed before and after harmonization, as well as variance associated with gestational age at birth and scan. Before harmonization, large cohort differences were observed. Harmonization removed all voxel-wise differences from MD maps and all metric means and histogram widths, however small voxel-wise differences (<1.5 % of voxels) remained in FA, AD and RD. We detected significant relationships between GA at birth and all metrics. When comparing single site and multisite harmonized datasets of equal sample sizes, harmonized data resulted in smaller standardized regression coefficients. ComBat could enable unprecedented sample sizes in developmental neuroscience, offering new horizons for biomarker discovery and validation, understanding typical and atypical brain development, and assessing neuroprotective therapies.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101488"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11683243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142814703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neural markers of error processing relate to task performance, but not to substance-related risks and problems and externalizing problems in adolescence and emerging adulthood. 错误处理的神经标记与任务表现有关,但与青少年和成年初期的物质相关风险和问题以及外化问题无关。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2024-12-24 DOI: 10.1016/j.dcn.2024.101500
Olga D Boer, Thea Wiker, Shervin H Bukhari, Rikka Kjelkenes, Clara M F Timpe, Irene Voldsbekk, Knut Skaug, Rune Boen, Valerie Karl, Torgeir Moberget, Lars T Westlye, Ingmar H A Franken, Hanan El Marroun, Rene J Huster, Christian K Tamnes
{"title":"Neural markers of error processing relate to task performance, but not to substance-related risks and problems and externalizing problems in adolescence and emerging adulthood.","authors":"Olga D Boer, Thea Wiker, Shervin H Bukhari, Rikka Kjelkenes, Clara M F Timpe, Irene Voldsbekk, Knut Skaug, Rune Boen, Valerie Karl, Torgeir Moberget, Lars T Westlye, Ingmar H A Franken, Hanan El Marroun, Rene J Huster, Christian K Tamnes","doi":"10.1016/j.dcn.2024.101500","DOIUrl":"10.1016/j.dcn.2024.101500","url":null,"abstract":"<p><p>Detecting errors and adapting behavior accordingly constitutes an integral aspect of cognition. Previous studies have linked neural correlates of error processing (e.g., error-related negativity (ERN) and error-related positivity (Pe)) to task performance and broader behavioral constructs, but few studies examined how these associations manifest in adolescence. In this study, we examined neural error processing markers and their behavioral associations in an adolescent/emerging adult sample (N = 143, M<sub>age</sub> = 18.0 years, range 11-25 years), employing a stop-signal task. Linear regressions were conducted using bootstrap resampling to explore associations between ERN/Pe peak amplitudes and latencies, stop accuracy, stop-signal reaction time (SSRT), and post-error slowing, as well as self-reported substance-related risks and problems and externalizing problems. After adjusting for age and sex, smaller frontocentral Pe amplitude and later Pe latency were associated with longer SSRT, and later Pe latency was associated with lower stop accuracy. This might indicate that the Pe, which is thought to reflect conscious error processing, reflects task performance on a response inhibition task better than the ERN, which reflects subconscious error processing. After correcting for multiple testing, there were no associations between ERN/Pe parameters and substance-related or externalizing problems, and no age interactions for these associations were detected.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101500"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732202/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EEG-based brain age prediction in infants-toddlers: Implications for early detection of neurodevelopmental disorders. 基于脑电图的婴幼儿脑年龄预测:对早期发现神经发育障碍的意义。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2024-12-18 DOI: 10.1016/j.dcn.2024.101493
Winko W An, Aprotim C Bhowmik, Charles A Nelson, Carol L Wilkinson
{"title":"EEG-based brain age prediction in infants-toddlers: Implications for early detection of neurodevelopmental disorders.","authors":"Winko W An, Aprotim C Bhowmik, Charles A Nelson, Carol L Wilkinson","doi":"10.1016/j.dcn.2024.101493","DOIUrl":"10.1016/j.dcn.2024.101493","url":null,"abstract":"<p><p>The infant brain undergoes rapid developmental changes in the first three years of life. Understanding these changes through the prediction of chronological age using neuroimaging can provide insights into typical and atypical brain development. We utilized 938 resting-state EEG recordings from 457 typically developing infants, 2 to 38 months old, to develop age prediction models. The multilayer perceptron model demonstrated the highest accuracy with an R<sup>2</sup> of 0.83 and a mean absolute error of 91.7 days. Feature importance analysis that combined hierarchical clustering and Shapley values identified two feature clusters describing periodic alpha and low beta activity as key predictors of age. Application of the model to EEG data from infants later diagnosed with autism or Down syndrome revealed significant underestimations of chronological age, supporting its potential as a clinical tool for early identification of alterations in brain development.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101493"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neural correlates of vicarious reward processing and peer victimization experiences in late childhood. 童年晚期替代奖赏处理和同伴伤害经历的神经相关性。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2024-12-24 DOI: 10.1016/j.dcn.2024.101499
Simone Dobbelaar, Sanne Kellij, René Veenstra, Berna Güroğlu
{"title":"Neural correlates of vicarious reward processing and peer victimization experiences in late childhood.","authors":"Simone Dobbelaar, Sanne Kellij, René Veenstra, Berna Güroğlu","doi":"10.1016/j.dcn.2024.101499","DOIUrl":"10.1016/j.dcn.2024.101499","url":null,"abstract":"<p><p>This preregistered study examined the neural correlates of vicarious reward processing and subsequent trust behavior in relation to experiences of victimization averaged over two years in late childhood. This study used a sample of children with prospective longitudinal data on peer victimization over the past two years (n<sub>behavioral</sub> = 83, 49.4 % girls, M<sub>age</sub> = 10.6 years, n<sub>fmri</sub> = 62). Participants played an fMRI vicarious reward task in which they could win or lose money for themselves and two other peers. The two other peers were experimentally manipulated to either include or exclude the participant in a Cyberball task prior to the task. Additionally, trust in the two peers was assessed using a one-shot trust game. Results revealed ventral striatum activation when winning (versus losing) for oneself, and activation in the dmPFC, vmPFC and precuneus when playing for excluders rather than for oneself. Victimization predicted decreased ventral striatum activation during personal rewards, and increased activation in the dorsomedial prefrontal cortex when playing for excluders rather than for oneself. Finally, averaged victimization was associated with increased differentiation in trust toward the including and excluding peers. Together, these findings contribute to our understanding of the social cognitions and behaviors of victims of bullying.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101499"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11743848/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142903876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fear extinction retention in children, adolescents, and adults. 儿童、青少年和成人的恐惧消退保持率。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2025-01-09 DOI: 10.1016/j.dcn.2025.101509
Ebba Widegren, Johan Vegelius, Matilda A Frick, Ashika A Roy, Stefan Möller, Johan Lundin Kleberg, Johanna Motilla Hoppe, Olof Hjorth, David Fällmar, Daniel S Pine, Karin Brocki, Malin Gingnell, Andreas Frick
{"title":"Fear extinction retention in children, adolescents, and adults.","authors":"Ebba Widegren, Johan Vegelius, Matilda A Frick, Ashika A Roy, Stefan Möller, Johan Lundin Kleberg, Johanna Motilla Hoppe, Olof Hjorth, David Fällmar, Daniel S Pine, Karin Brocki, Malin Gingnell, Andreas Frick","doi":"10.1016/j.dcn.2025.101509","DOIUrl":"10.1016/j.dcn.2025.101509","url":null,"abstract":"<p><p>Past results suggest that fear extinction and the return of extinguished fear are compromised in adolescents. However, findings have been inconclusive as there is a lack of fear extinction and extinction retention studies including children, adolescents and adults. In the present study, 36 children (6-9 years), 40 adolescents (13-17 years) and 44 adults (30-40 years), underwent a two-day fear conditioning task. Habituation, acquisition, and extinction were performed on the first day and an extinction retention test > 24 h later. Skin conductance responses were recorded during all phases of fear conditioning and functional magnetic resonance imaging (fMRI) was conducted during the fear retention test. All groups acquired and extinguished fear as measured with SCR, with no group differences in SCR during extinction retention. The groups had largely similar neural fear responses during the retention test, apart from adolescents displaying stronger amygdala fear response than children, with no differences between adolescents and adults. The findings do not support an adolescent extinction dip, and there was only marginal evidence of progressive changes in fear conditioning across development. In contrast to findings in rodents, fear conditioning in humans may elicit similar physiological responses and recruit similar neural networks from childhood to adulthood.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101509"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sample size estimation for task-related functional MRI studies using Bayesian updating. 用贝叶斯更新估计任务相关功能MRI研究的样本量。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2024-12-17 DOI: 10.1016/j.dcn.2024.101489
Eduard T Klapwijk, Joran Jongerling, Herbert Hoijtink, Eveline A Crone
{"title":"Sample size estimation for task-related functional MRI studies using Bayesian updating.","authors":"Eduard T Klapwijk, Joran Jongerling, Herbert Hoijtink, Eveline A Crone","doi":"10.1016/j.dcn.2024.101489","DOIUrl":"10.1016/j.dcn.2024.101489","url":null,"abstract":"<p><p>Task-related functional MRI (fMRI) studies need to be properly powered with an adequate sample size to reliably detect effects of interest. But for most fMRI studies, it is not straightforward to determine a proper sample size using power calculations based on published effect sizes. Here, we present an alternative approach of sample size estimation with empirical Bayesian updating. First, this method provides an estimate of the required sample size using existing data from a similar task and similar region of interest. Using this estimate researchers can plan their research project, and report empirically determined sample size estimations in their research proposal or pre-registration. Second, researchers can expand the sample size estimations with new data. We illustrate this approach using four existing fMRI data sets where Cohen's d is the effect size of interest for the hemodynamic response in the task condition of interest versus a control condition, and where a Pearson correlation between task effect and age is the covariate of interest. We show that sample sizes to reliably detect effects differ between various tasks and regions of interest. We provide an R package to allow researchers to use Bayesian updating with other task-related fMRI studies.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101489"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural brain basis of latent factors of executive functions in childhood. 儿童执行功能潜在因素的脑结构基础。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2024-12-28 DOI: 10.1016/j.dcn.2024.101504
Yongjing Li, Keertana Ganesan, Claire R Smid, Abigail Thompson, Roser Cañigueral, Jessica Royer, Boris Bernhardt, Nikolaus Steinbeis
{"title":"Structural brain basis of latent factors of executive functions in childhood.","authors":"Yongjing Li, Keertana Ganesan, Claire R Smid, Abigail Thompson, Roser Cañigueral, Jessica Royer, Boris Bernhardt, Nikolaus Steinbeis","doi":"10.1016/j.dcn.2024.101504","DOIUrl":"10.1016/j.dcn.2024.101504","url":null,"abstract":"<p><p>Executive functions can be classified into processes of inhibition, working memory and shifting, which together support flexible and goal-directed behaviour and are crucial for both current and later-life outcomes. A large body of literature has identified distinct brain regions critical to performing each of these functions. These findings are however predicated on a piecemeal and single-task approach. It is therefore unclear to what extent these associations reflect task-specific features or actual constructs of executive functions. Here, in a sample of 141 children aged 6-13 years, we administered a battery of 9 executive function tasks, derived latent factors of inhibition, working memory, and shifting and examined their associations with markers of brain structure (whole-brain cortical thickness). We identified associations between working memory and cortical thickness of right superior frontal and left medial temporal lobe as well as associations between shifting and cortical thickness in bilateral frontal and occipital lobes and left medial and anterior temporal lobes. While working memory and shifting shared a cortical substrate in right superior frontal cortex as well as left middle and inferior temporal regions no significant brain clusters were associated with inhibition. We discuss these findings in relation to theories of executive functions and their development.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101504"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11780108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142957549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sports participation & childhood neurocognitive development. 运动参与与儿童神经认知发展。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2024-12-18 DOI: 10.1016/j.dcn.2024.101492
Fu-Miao Tan, Junhong Yu, Alicia M Goodwill
{"title":"Sports participation & childhood neurocognitive development.","authors":"Fu-Miao Tan, Junhong Yu, Alicia M Goodwill","doi":"10.1016/j.dcn.2024.101492","DOIUrl":"10.1016/j.dcn.2024.101492","url":null,"abstract":"<p><p>Various psychosocial factors like collaboration inherent to team sports might provide a more dynamic environment for cognitive challenges that could foster enhanced neurocognitive development compared to individual sports. We investigated the impact of different organised sports on neurocognitive development in children (N = 11,878; aged 9-11) from the Adolescent Brain Cognitive Development (ABCD) study. Participants were classified into four categories based on their sports involvement at baseline and two years later: none, individual-based, team-based, or both. Cross-sectional and longitudinal analyses were conducted on 11 cognitive tests and neuroimaging metrics (i.e., resting-state functional connectivity and various grey matter (GM) and white matter (WM) measurements) between sport groups. A comparison between team and individual sports yielded no significant differences in cognitive measures at baseline and follow-up. Similarly, although WM microstructural differences were significant, the effect size was small. However, participation in any sport at baseline was associated with superior performance in various cognitive domains (i.e. inhibition, processing speed, and others), greater subcortical GM volume (i.e. cerebellum cortex, amygdala, hippocampus, and others), and whole-brain WM integrity compared to non-participants. Results suggest a positive association between organised sports participation, specifically individual and team-based sports, and neurocognitive development. However, further investigation is warranted to determine the nuanced effects of different sports on neurocognitive development.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101492"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of the hippocampus in working memory and word reading: Novel neural correlates of reading among youth living in the context of economic disadvantage. 海马体在工作记忆和单词阅读中的作用:生活在经济劣势背景下的青少年阅读的新神经关联。
IF 4.6 2区 医学
Developmental Cognitive Neuroscience Pub Date : 2025-01-01 Epub Date: 2024-12-16 DOI: 10.1016/j.dcn.2024.101491
E T Marcelle, H Yang, J W Cohen, B Ramphal, D Pagliaccio, V Rauh, B S Peterson, F Perera, H Andrews, A G Rundle, J Herbstman, A E Margolis
{"title":"The role of the hippocampus in working memory and word reading: Novel neural correlates of reading among youth living in the context of economic disadvantage.","authors":"E T Marcelle, H Yang, J W Cohen, B Ramphal, D Pagliaccio, V Rauh, B S Peterson, F Perera, H Andrews, A G Rundle, J Herbstman, A E Margolis","doi":"10.1016/j.dcn.2024.101491","DOIUrl":"10.1016/j.dcn.2024.101491","url":null,"abstract":"<p><p>A left-lateralized cortical reading circuit underlies successful reading and fails to engage in individuals with reading problems. Studies identifying this circuit included youth from economically advantaged backgrounds and focused on cortical, not subcortical, structures. However, among youth with low scores on reading tests who are living in the context of economic disadvantage, this brain network is actively engaged during reading, despite persistent reading problems. This finding suggests that other brain circuits may underlie reading in these youth. A hippocampal circuit is one likely candidate, as it has recently been shown to support domain-general processes like working memory (WM) that are also associated with reading. Given age-related increases in hippocampal volume, WM, and reading, and known associations between WM and reading, we hypothesized that hippocampal volume would be associated with reading via WM processes. Using a cross-sectional developmental design, we explored this in middle childhood (average age at MRI scan ∼10; N = 50) and adolescence (average age at MRI scan ∼17; N = 175). Results suggest that the hippocampus is a critical contributor to word reading in adolescents living in economically disadvantaged contexts, and that this operates through working memory processes. Such findings point to new targets for reading intervention in adolescents.</p>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"71 ","pages":"101491"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11783422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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