Developmental Cognitive Neuroscience最新文献_第6页

Enhancing causal inference in population-based neuroimaging data in children and adolescents 加强基于人群的儿童和青少年神经影像数据的因果推理。

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-10-19 DOI: 10.1016/j.dcn.2024.101465

Rachel Visontay , Lindsay M. Squeglia , Matthew Sunderland , Emma K. Devine , Hollie Byrne , Louise Mewton

{"title":"Enhancing causal inference in population-based neuroimaging data in children and adolescents","authors":"Rachel Visontay , Lindsay M. Squeglia , Matthew Sunderland , Emma K. Devine , Hollie Byrne , Louise Mewton","doi":"10.1016/j.dcn.2024.101465","DOIUrl":"10.1016/j.dcn.2024.101465","url":null,"abstract":"<div><div>Recent years have seen the increasing availability of large, population-based, longitudinal neuroimaging datasets, providing unprecedented capacity to examine brain-behavior relationships in the neurodevelopmental context. However, the ability of these datasets to deliver <em>causal</em> insights into brain-behavior relationships relies on the application of purpose-built analysis methods to counter the biases that otherwise preclude causal inference from observational data. Here we introduce these approaches (i.e., propensity score-based methods, the ‘G-methods’, targeted maximum likelihood estimation, and causal mediation analysis) and conduct a review to determine the extent to which they have been applied thus far in the field of developmental cognitive neuroscience. We identify just eight relevant studies, most of which employ propensity score-based methods. Many approaches are entirely absent from the literature, particularly those that promote causal inference in settings with complex, multi-wave data and repeated neuroimaging assessments. Causality is central to an etiological understanding of the relationship between the brain and behavior, as well as for identifying targets for prevention and intervention. Careful application of methods for causal inference may help the field of developmental cognitive neuroscience approach these goals.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"70 ","pages":"Article 101465"},"PeriodicalIF":4.6,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delay discounting in adolescence depends on whom you wait for: Evidence from a functional neuroimaging study 青春期的延迟折现取决于你在等谁？功能神经影像学研究的证据

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-10-18 DOI: 10.1016/j.dcn.2024.101463

Lotte H. van Rijn , Suzanne van de Groep , Michelle Achterberg , Lara Wierenga , Barbara R. Braams , Valeria Gazzola , Berna Güroğlu , Christian Keysers , Lucres Nauta-Jansen , Anna van Duijvenvoorde , Lydia Krabbendam , Eveline A. Crone

{"title":"Delay discounting in adolescence depends on whom you wait for: Evidence from a functional neuroimaging study","authors":"Lotte H. van Rijn , Suzanne van de Groep , Michelle Achterberg , Lara Wierenga , Barbara R. Braams , Valeria Gazzola , Berna Güroğlu , Christian Keysers , Lucres Nauta-Jansen , Anna van Duijvenvoorde , Lydia Krabbendam , Eveline A. Crone","doi":"10.1016/j.dcn.2024.101463","DOIUrl":"10.1016/j.dcn.2024.101463","url":null,"abstract":"<div><div>With age, adolescents increasingly demonstrate the ability to forgo immediate, smaller rewards in favor of larger delayed rewards, indicating reduced delay discounting. Adolescence is also a time of social reorientation, where decisions not only involve weighing immediate against future outcomes, but also consequences for self versus those for others. In this functional Magnetic Resonance Imaging study, we examined the neural correlates of immediate and delayed reward choices where the delayed outcomes could benefit self, friends, or unknown others. A total of 196 adolescent twins aged 14–17 completed a social delay discounting task, with fMRI data acquired from 174 participants. Out of these, 156 adolescents had valid fMRI data, and 138 adolescents had observations in every condition. Adolescents more often chose the immediate reward when it was larger, and when the delay was longer. Area-under-the-curve (AUC) comparisons revealed that behavior differed across delay-beneficiaries, with AUC being highest for the self, followed by friends, and lowest for unknown others. This suggests that adolescents are more willing to wait for rewards for self. Neuroimaging analyses showed increased activity in the midline areas medial prefrontal cortex (MPFC) and precuneus, as well as bilateral temporal parietal junction (TPJ) when considering delayed reward for unknown others and friends compared to self. A whole-brain interaction with choice showed that the bilateral insula and right dorsolateral prefrontal cortex (DLPFC) were more active for delayed choices for unknown others and for immediate choices for friends and self. This underscores that the neuro-cognitive processing of how delays reduce the value of rewards depends on closeness of the beneficiary.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"70 ","pages":"Article 101463"},"PeriodicalIF":4.6,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142578546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Responsible use of population neuroscience data: Towards standards of accountability and integrity. 负责任地使用群体神经科学数据：制定问责和诚信标准。

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-10-18 DOI: 10.1016/j.dcn.2024.101466

Sandra A Brown, Hugh Garavan, Terry L Jernigan, Susan F Tapert, Rebekah S Huber, Daniel Lopez, Traci Murray, Gayathri Dowling, Elizabeth A Hoffman, Lucina Q Uddin

引用次数: 0

Early childhood family threat and longitudinal amygdala-mPFC circuit development: Examining cortical thickness and gray matter-white matter contrast 童年早期的家庭威胁与杏仁核-前脑皮质回路的纵向发展：检查皮质厚度和灰质-白质对比

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-10-16 DOI: 10.1016/j.dcn.2024.101462

Sandra Thijssen , Yllza Xerxa , Linn B. Norbom , Maaike Cima , Henning Tiemeier , Christian K. Tamnes , Ryan L. Muetzel

{"title":"Early childhood family threat and longitudinal amygdala-mPFC circuit development: Examining cortical thickness and gray matter-white matter contrast","authors":"Sandra Thijssen , Yllza Xerxa , Linn B. Norbom , Maaike Cima , Henning Tiemeier , Christian K. Tamnes , Ryan L. Muetzel","doi":"10.1016/j.dcn.2024.101462","DOIUrl":"10.1016/j.dcn.2024.101462","url":null,"abstract":"<div><div>Early threat-associated cortical thinning may be interpreted as accelerated cortical development. However, non-adaptive processes may show similar macrostructural changes. Examining cortical thickness (CT) together with grey/white-matter contrast (GWC), a proxy for intracortical myelination, may enhance the interpretation of CT findings. In this prospective study, we examined associations between early life family-related threat (harsh parenting, family conflict, and neighborhood safety) and CT and GWC development from late childhood to middle adolescence. MRI was acquired from 4200 children (2069 boys) from the Generation R study at ages 8, 10 and 14 years (in total 6114 scans), of whom 1697 children had >1 scans. Linear mixed effect models were used to examine family factor-by-age interactions on amygdala volume, caudal and rostral anterior cingulate (ACC) and medial orbitofrontal cortex (mOFC) CT and GWC. A neighborhood safety-by-age-interaction was found for rostral ACC GWC, suggesting less developmental change in children from unsafe neighborhoods. Moreover, after more stringent correction for motion, family conflict was associated with greater developmental change in CT but less developmental change in GWC. Results suggest that early threat may blunt ACC GWC development. Our results, therefore, do not provide evidence for accelerated threat-associated structural development of the amygdala-mPFC circuit between ages 8–14 years.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"70 ","pages":"Article 101462"},"PeriodicalIF":4.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Brain-phenotype predictions of language and executive function can survive across diverse real-world data: Dataset shifts in developmental populations 大脑表型对语言和执行功能的预测可以在不同的真实世界数据中存活：发育人群中的数据集转移。

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-10-16 DOI: 10.1016/j.dcn.2024.101464

Brendan D. Adkinson , Matthew Rosenblatt , Javid Dadashkarimi , Link Tejavibulya , Rongtao Jiang , Stephanie Noble , Dustin Scheinost

{"title":"Brain-phenotype predictions of language and executive function can survive across diverse real-world data: Dataset shifts in developmental populations","authors":"Brendan D. Adkinson , Matthew Rosenblatt , Javid Dadashkarimi , Link Tejavibulya , Rongtao Jiang , Stephanie Noble , Dustin Scheinost","doi":"10.1016/j.dcn.2024.101464","DOIUrl":"10.1016/j.dcn.2024.101464","url":null,"abstract":"<div><div>Predictive modeling potentially increases the reproducibility and generalizability of neuroimaging brain-phenotype associations. Yet, the evaluation of a model in another dataset is underutilized. Among studies that undertake external validation, there is a notable lack of attention to generalization across dataset-specific idiosyncrasies (i.e., dataset shifts). Research settings, by design, remove the between-site variations that real-world and, eventually, clinical applications demand. Here, we rigorously test the ability of a range of predictive models to generalize across three diverse, unharmonized developmental samples: the Philadelphia Neurodevelopmental Cohort (n=1291), the Healthy Brain Network (n=1110), and the Human Connectome Project in Development (n=428). These datasets have high inter-dataset heterogeneity, encompassing substantial variations in age distribution, sex, racial and ethnic minority representation, recruitment geography, clinical symptom burdens, fMRI tasks, sequences, and behavioral measures. Through advanced methodological approaches, we demonstrate that reproducible and generalizable brain-behavior associations can be realized across diverse dataset features. Results indicate the potential of functional connectome-based predictive models to be robust despite substantial inter-dataset variability. Notably, for the HCPD and HBN datasets, the best predictions were not from training and testing in the same dataset (i.e., cross-validation) but across datasets. This result suggests that training on diverse data may improve prediction in specific cases. Overall, this work provides a critical foundation for future work evaluating the generalizability of brain-phenotype associations in real-world scenarios and clinical settings.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"70 ","pages":"Article 101464"},"PeriodicalIF":4.6,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Leveraging mixed-effects location scale models to assess the ERP mismatch negativity’s psychometric properties and trial-by-trial neural variability in toddler-mother dyads 利用混合效应位置标度模型评估ERP失配负性的心理测量特性和幼儿-母亲二人组的逐次试验神经变异性。

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-10-12 DOI: 10.1016/j.dcn.2024.101459

Serena K. Mon , Brittany L. Manning , Lauren S. Wakschlag , Elizabeth S. Norton

{"title":"Leveraging mixed-effects location scale models to assess the ERP mismatch negativity’s psychometric properties and trial-by-trial neural variability in toddler-mother dyads","authors":"Serena K. Mon , Brittany L. Manning , Lauren S. Wakschlag , Elizabeth S. Norton","doi":"10.1016/j.dcn.2024.101459","DOIUrl":"10.1016/j.dcn.2024.101459","url":null,"abstract":"<div><div>Trial-by-trial neural variability, a measure of neural response stability, has been examined in relation to behavioral indicators using summary measures, but these methods do not characterize meaningful processes underlying variability. Mixed-effects location scale models (MELSMs) overcome these limitations by accounting for predictors and covariates of variability but have been rarely used in developmental studies. Here, we applied MELSMs to the ERP auditory mismatch negativity (MMN), a neural measure often related to language and psychopathology. 84 toddlers and 76 mothers completed a speech-syllable MMN paradigm. We extracted early and late MMN mean amplitudes from trial-level waveforms. We first characterized our sample’s psychometric properties using MELSMs and found a wide range of subject-level internal consistency. Next, we examined the relation between toddler MMNs with theoretically relevant child behavioral and maternal variables. MELSMs offered better model fit than analyses that assumed constant variability. We found significant individual differences in trial-by-trial variability but no significant associations between toddler variability and their language, irritability, or mother variability indices. Overall, we illustrate how MELSMs can characterize psychometric properties and answer questions about individual differences in variability. We provide recommendations and resources as well as example code for analyzing trial-by-trial neural variability in future studies.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"70 ","pages":"Article 101459"},"PeriodicalIF":4.6,"publicationDate":"2024-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measurement of emerging neurocognitive and language skills in the HEALthy Brain and Child Development (HBCD) study 在 HEALthy Brain and Child Development (HBCD) 研究中测量新出现的神经认知和语言技能。

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-09-28 DOI: 10.1016/j.dcn.2024.101461

Julie A. Kable , Alexandra S. Potter , Natacha Akshoomoff , Patricia M. Blasco , Stefanie C. Bodison , Lucia Ciciolla , Sherry DeGray , Zoe Hulce , Emily S. Kuschner , Britley Learnard , Monica Luciana , Alexandra Perez , Miriam A. Novack , Tracy Riggins , So Yeon Shin , Sidney Smith , Jennifer Vannest , Eric.H. Zimak , the HBCD Neurocognitive and Language (NCL) Workgroup

{"title":"Measurement of emerging neurocognitive and language skills in the HEALthy Brain and Child Development (HBCD) study","authors":"Julie A. Kable , Alexandra S. Potter , Natacha Akshoomoff , Patricia M. Blasco , Stefanie C. Bodison , Lucia Ciciolla , Sherry DeGray , Zoe Hulce , Emily S. Kuschner , Britley Learnard , Monica Luciana , Alexandra Perez , Miriam A. Novack , Tracy Riggins , So Yeon Shin , Sidney Smith , Jennifer Vannest , Eric.H. Zimak , the HBCD Neurocognitive and Language (NCL) Workgroup","doi":"10.1016/j.dcn.2024.101461","DOIUrl":"10.1016/j.dcn.2024.101461","url":null,"abstract":"<div><div>The HEALthy Brain and Child Development (HBCD) study, a multi-site prospective longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. The study plans enrolling over 7000 families across 27 sites. This manuscript presents the measures from the Neurocognition and Language Workgroup. Constructs were selected for their importance in normative development, evidence for altered trajectories associated with environmental influences, and predictive validity for child outcomes. Evaluation of measures considered psychometric properties, brevity, and developmental and cultural appropriateness. Both performance measures and caregiver report were used wherever possible. A balance of norm-referenced global measures of development (e.g., Bayley Scales of Infant Development-4) and more specific laboratory measures (e.g., deferred imitation) are included in the HBCD study battery. Domains of assessment include sensory processing, visual-spatial reasoning, expressive and receptive language, executive function, memory, numeracy, adaptive behavior, and neuromotor. Strategies for staff training and quality control procedures, as well as anticipated measures to be added as the cohort ages, are reviewed. The HBCD study presents a unique opportunity to examine early brain and neurodevelopment in young children through a lens that accounts for prenatal exposures, health and socio-economic disparities.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"70 ","pages":"Article 101461"},"PeriodicalIF":4.6,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancing the reporting of pediatric EEG data: Tools for estimating reliability, effect size, and data quality metrics 推进儿科脑电图数据的报告工作：估计可靠性、效应大小和数据质量指标的工具

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-09-28 DOI: 10.1016/j.dcn.2024.101458

Wenyi Xu , Alexa D. Monachino , Sarah A. McCormick , Emma T. Margolis , Ana Sobrino , Cara Bosco , Cassandra J. Franke , Lauren Davel , Michal R. Zieff , Kirsten A. Donald , Laurel J. Gabard-Durnam , Santiago Morales

{"title":"Advancing the reporting of pediatric EEG data: Tools for estimating reliability, effect size, and data quality metrics","authors":"Wenyi Xu , Alexa D. Monachino , Sarah A. McCormick , Emma T. Margolis , Ana Sobrino , Cara Bosco , Cassandra J. Franke , Lauren Davel , Michal R. Zieff , Kirsten A. Donald , Laurel J. Gabard-Durnam , Santiago Morales","doi":"10.1016/j.dcn.2024.101458","DOIUrl":"10.1016/j.dcn.2024.101458","url":null,"abstract":"<div><div>EEG studies play a crucial role in enhancing our understanding of brain development across the lifespan. The increasing clinical and policy implications of EEG research underscore the importance of utilizing reliable EEG measures and increasing the reproducibility of EEG studies. However, important data characteristics like reliability, effect sizes, and data quality metrics are often underreported in pediatric EEG studies. This gap in reporting could stem from the lack of accessible computational tools for quantifying these metrics for EEG data. To help address the lack of reporting, we developed a toolbox that facilitates the estimation of internal consistency reliability, effect size, and standardized measurement error with user-friendly software that facilitates both computing and interpreting these measures. In addition, our tool provides subsampled reliability and effect size in increasing numbers of trials. These estimates offer insights into the number of trials needed for detecting significant effects and reliable measures, informing the minimum number of trial thresholds for the inclusion of participants in individual difference analyses and the optimal trial number for future study designs. Importantly, our toolbox is integrated into commonly used preprocessing pipelines to increase the estimation and reporting of data quality metrics in developmental neuroscience.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"70 ","pages":"Article 101458"},"PeriodicalIF":4.6,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142552623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive control processes and emotion regulation in adolescence: Examining the impact of affective inhibition and heart-rate-variability on emotion regulation dynamics in daily life 青春期的认知控制过程和情绪调节：研究情感抑制和心率变异对日常生活中情绪调节动态的影响

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-09-26 DOI: 10.1016/j.dcn.2024.101454

Gillian Debra, Nathalie Michels, Matteo Giletta

{"title":"Cognitive control processes and emotion regulation in adolescence: Examining the impact of affective inhibition and heart-rate-variability on emotion regulation dynamics in daily life","authors":"Gillian Debra, Nathalie Michels, Matteo Giletta","doi":"10.1016/j.dcn.2024.101454","DOIUrl":"10.1016/j.dcn.2024.101454","url":null,"abstract":"<div><div>Cognitive control processes likely influence the extent to which adolescents can successfully regulate their emotions. This study examined whether individual differences in affective inhibition and heart rate variability (HRV), as a peripheral index of cognitive control, moderated the association between momentary emotion regulation and negative affect (NA). Ecological Momentary Assessments (EMA) over 14 days were obtained in 235 adolescents (<em>M</em><sub><em>age</em></sub> = 13.48 years; 106 females). At each assessment, participants reported their current NA and the extent to which they used cognitive reappraisal and rumination. Moreover, at three time points (approximately 1 year, 6 months, and just before the EMA), affective inhibition was assessed using an affective go/no-go task and HRV was recorded at rest. Results indicate that adolescents with lower affective inhibition reported lower average levels of daily rumination. However, affective inhibition did not moderate the association between either daily cognitive reappraisal or rumination and momentary NA. Consistent with hypotheses, the association between momentary rumination and NA was weaker in adolescents showing higher levels of resting HRV. Overall, findings may underscore the importance of interventions targeting HRV as a malleable factor for enhancing adolescents’ affective well-being.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"70 ","pages":"Article 101454"},"PeriodicalIF":4.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the late maturation of an intrinsic episodic memory network: A resting-state fMRI study 探索内在外显记忆网络的晚期成熟：静息态 fMRI 研究。

IF 4.6 2区医学

Developmental Cognitive Neuroscience Pub Date : 2024-09-26 DOI: 10.1016/j.dcn.2024.101453

Miguel Ângelo Andrade , Ana Raposo , Alexandre Andrade

{"title":"Exploring the late maturation of an intrinsic episodic memory network: A resting-state fMRI study","authors":"Miguel Ângelo Andrade , Ana Raposo , Alexandre Andrade","doi":"10.1016/j.dcn.2024.101453","DOIUrl":"10.1016/j.dcn.2024.101453","url":null,"abstract":"<div><div>Previous research suggests that episodic memory relies on functional neural networks,which are present even in the absence of an explicit task. The regions that integrate.these networks and the developmental changes in intrinsic functional connectivity.remain elusive. In the present study, we outlined an intrinsic episodic memory network.(iEMN) based on a systematic selection of functional connectivity studies, and.inspected network differences in resting-state fMRI between adolescents (13–17 years.old) and adults (23–27 years old) from the publicly available NKI-Rockland Sample.Through a review of brain regions commonly associated with episodic memory.networks, we identified a potential iEMN composed by 14 bilateral ROIs, distributed.across temporal, frontal and parietal lobes. Within this network, we found an increase.in resting-state connectivity from adolescents to adults between the right temporal pole.and two regions in the right lateral prefrontal cortex. We argue that the coordination of.these brain regions, connecting areas of semantic processing and areas of controlled.retrieval, arises as an important feature towards the full maturation of the episodic.memory system. The findings add to evidence suggesting that adolescence is a key.period in memory development and highlights the role of intrinsic functional.connectivity in such development.</div></div>","PeriodicalId":49083,"journal":{"name":"Developmental Cognitive Neuroscience","volume":"70 ","pages":"Article 101453"},"PeriodicalIF":4.6,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142378453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0