American Journal of Drug and Alcohol Abuse最新文献

{"title":"Substance use disorders and pharmacotherapies: exploring public knowledge and supportive attitudes.","authors":"Callie L Wang, Lidia Z Meshesha, Jacqueline Woerner, Tatiana D Magri, Minh D Nguyen, Jenni B Teeters","doi":"10.1080/00952990.2025.2450416","DOIUrl":"10.1080/00952990.2025.2450416","url":null,"abstract":"<p><p><i>Background:</i> Despite available and effective prevention and treatment strategies for substance use disorders (SUD), drug overdose deaths in the US remain high. Further, limited public knowledge of SUD pharmacotherapies may contribute to increased stigmatization toward SUD medications and a lack of willingness to help people with SUD.<i>Objectives:</i> This study evaluated knowledge and attitudes about SUD pharmacotherapies and willingness to help people with SUD among a sample of U.S. adults.<i>Method:</i> Participants recruited through Amazon's Mechanical Turk (<i>N</i> = 314; 62.1% male) completed online surveys evaluating knowledge, attitudes, and willingness to help by various demographic factors, history of substance use, and experience with someone with SUD.<i>Results:</i> Results revealed a significant difference in attitudes by race/ethnicity (F(1,307) = 11.85, <i>p</i> < .001). Participants with a personal history of substance use exhibited greater knowledge (F(1,312) = 31.94, <i>p</i> < .001) and willingness to help someone with a SUD (F(1,312) = 7.84, <i>p</i> = .005). Participants with experience with someone with a SUD also exhibited greater knowledge (F(1,311) = 19.42, <i>p</i> < .001) and willingness to help (F(1,311) = 13.63, <i>p</i> < .001).<i>Conclusion:</i> Results emphasize the importance of targeted education to bridge gaps in knowledge, enhance public attitudes, and promote willingness to help individuals with SUD. Utilizing public health strategies that promote empathy, willingness to help, and increase accessibility and acceptance of SUD treatment options, could be potential avenues that ultimately improve outcomes for individuals with SUD.</p>","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"127-136"},"PeriodicalIF":2.7,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11962821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Readiness to stop smoking and subsequent switching away to electronic nicotine delivery systems among adults who smoke cigarettes.","authors":"Saul Shiffman, Sooyong Kim, Nicholas I Goldenson, Mark A Sembower","doi":"10.1080/00952990.2024.2439363","DOIUrl":"10.1080/00952990.2024.2439363","url":null,"abstract":"<p><p><i>Background:</i> Adults who smoke cigarettes (AWS) who switch to electronic nicotine delivery systems (ENDS) are likely to reduce their health risks.<i>Objectives:</i> To explore ENDS-users' readiness to stop smoking (RTSS) when adopting ENDS, the prospective association of RTSS and switching away from smoking (past-30-day abstinence), and the role of frequency of JUUL use in switching.<i>Methods:</i> Analyses used data from a naturalistic 2-year longitudinal study of 17,393 AWS (55.4% male) who had purchased a JUUL Starter Kit.<i>Results:</i> Only 20% were planning to stop smoking within 7 days at baseline but had the highest likelihood of switching, 70% at Month-24 (vs. in a year or more: OR = 2.33; 95%CI = 2.13-2.55). Those planning to stop smoking within 30 days (24%), 6 months (24%) or a year or more (27%) had switch rates of 53 ~ 59% at Month-24; those who planned never to quit (6%) had 51% switch rates. Daily ENDS use was prospectively associated with the highest likelihood of subsequent switching (vs. infrequent: OR = 1.68; 95%CI = 1.60-1.77); frequent users (≥20 days/month) also had higher switch rates (OR = 1.22; 95%CI = 1.15-1.28). Descriptively, participants higher on RTSS were more likely to be daily or frequent users, but frequency of use neither interacted with RTSS, nor mediated its association with switching.<i>Conclusions:</i> Most ENDS adopters were not ready to stop smoking, and would not be candidates for cessation treatment. However, a majority - even of those never planning to quit - were abstinent from cigarettes two years later. ENDS may facilitate smoking abstinence in populations not reached by traditional cessation interventions.</p>","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"328-338"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How adolescent tobacco use has responded to state tobacco 21 laws and flavor restrictions.","authors":"Summer Sherburne Hawkins, Rebekah Levine Coley, Lindsay Lanteri, Christopher F Baum","doi":"10.1080/00952990.2024.2444567","DOIUrl":"10.1080/00952990.2024.2444567","url":null,"abstract":"<p><p><i>Background:</i> Tobacco 21 (T21) laws (prohibiting tobacco sales under age 21) and flavor restrictions have recently been enacted, yet little is known about the extent to which these policies shifted adolescent tobacco use.<i>Objectives:</i> To examine the associations between state-level T21 laws and flavor restrictions with adolescent tobacco use overall and by age.<i>Methods:</i> We linked state-level T21 laws and flavor restrictions with individual-level data on self-reported levels of cigarette, cigar, and electronic nicotine delivery systems (ENDS) use among 979,477 (500,205 female/479,272 male) 14-18+-year-olds from the 2011-2021 Youth Risk Behavior Surveys. We estimated adjusted zero-inflated negative binomial regression models to predict the likelihood of zero use and frequency of use among users and calculated total predicted use, with year and state fixed effects.<i>Results:</i> There were no associations between flavor restrictions and cigarette, cigar, or ENDS use. There also were no associations between T21 laws and cigarette use; however, when categorized based on the laws' policy components, strong T21 laws were associated with lower cigarette use (total marginal effect estimate: -0.34; -0.59, -0.09; <i>p</i> = .009, showing a 0.34 day/month decline). T21 laws were associated with higher ENDS use (total marginal effect estimate: 0.36; 0.11, 0.60; <i>p</i> = .004, showing a 0.36 day/month increase). Policy effects did not vary by age.<i>Conclusion:</i> Current state policies aimed at reducing access to tobacco products have not curbed adolescent tobacco use. Our findings suggest that more comprehensive state laws, including T21 laws with strong policy components, are needed to fill gaps in federal age and flavor restrictions.</p>","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"360-371"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reducing stigma and expanding methadone access in the U.S.: the <i>Modernizing Opioid Treatment Access Act</i> and beyond.","authors":"Julio C Nunes, Bryon Adinoff","doi":"10.1080/00952990.2025.2525405","DOIUrl":"10.1080/00952990.2025.2525405","url":null,"abstract":"<p><p>The <i>Modernizing Opioid Treatment Access</i> (MOTA) Act proposes reforms to methadone regulation by allowing addiction physician specialists to prescribe up to 30-day doses through community pharmacies. This perspective examines the bill's implications, implementation challenges, and future policy directions to improve equitable access to methadone. While opioid treatment programs have played a critical role in methadone delivery, their restrictive model can increase stigma and limit access, particularly in underserved areas. The COVID-19 pandemic demonstrated that 30-day take-home methadone-dispensed through opioid treatment programs-could be implemented safely in the U.S. and international pharmacy-dispensing models further support a less restrictive approach. However, successful implementation requires addressing inadequate prescriber training, pharmacy participation barriers, and insurance coverage limitations. Expanding methadone access through pharmacies is a step toward integrating addiction treatment into mainstream healthcare. If able to effectively increase accessibility, the MOTA Act may also help reduce stigma and improve outcomes for individuals with opioids use disorder.</p>","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"413-418"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144734528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A scoping review of interventions for engaging adolescents and young adults in opioid use disorder treatment across the care cascade.","authors":"Sarah J Miller, Sayward E Harrison, Steven B Harrod, Kimberly J Hills, Alain Litwin","doi":"10.1080/00952990.2024.2443938","DOIUrl":"10.1080/00952990.2024.2443938","url":null,"abstract":"<p><p><i>Background:</i> A high number of adolescents and young adults engage in opioid misuse and/or meet criteria for opioid use disorder (OUD). Youth also experience worse treatment outcomes when compared to adult counterparts.<i>Objectives:</i> This scoping review aimed to identify and summarize existing interventions designed to increase engagement of youth across the OUD care cascade, as well as describe clinical and research implications.<i>Methods:</i> Peer-reviewed literature was searched using PubMed, PsycInfo, and Web of Science. Studies were eligible if they presented outcomes of an intervention focused on engaging adolescents and young adults (ages 12-25 years) in the OUD care cascade and were published in English.<i>Results:</i> Nine articles met inclusion criteria that described interventions for adolescents and young adults across engagement, initiation, and retention in the OUD care cascade. Several strategies were used in interventions, including behavioral health and integrated health services, contingency management, meaningful family involvement, assertive outreach, and provider trainings/consultation. Only one intervention has been tested with a randomized control trial.<i>Conclusions:</i> Due to small sample sizes and lack of control groups, findings from existing intervention studies do not indicate which strategies are most effective. Further research is urgently needed to develop and evaluate effective interventions for youth with OUD. Providers working with youth should implement services to meet youth's individual needs. Providers should consider utilizing integrated services and referrals to behavioral health, involving family in treatment, and use of contingency management and assertive outreach. Continuing education for providers on OUD treatment and developmental concerns is also crucially needed.</p>","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"290-307"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using digitally delivered measurement-based care in substance use disorder treatment: qualitative analysis of patients' perspectives.","authors":"Tessa Frohe, Eliza B Cohn, Madeline C Frost, Tascha R Johnson, Kevin A Hallgren","doi":"10.1080/00952990.2025.2458626","DOIUrl":"10.1080/00952990.2025.2458626","url":null,"abstract":"<p><p><i>Background:</i> Measurement-based care (MBC) is a clinical practice where patients complete standardized outcome measures throughout treatment to monitor clinical progress and inform clinical decision-making. However, MBC is rarely adopted in routine substance use disorder (SUD) treatment. We developed a digital MBC system and pilot tested it in an outpatient adult community SUD treatment setting.<i>Objectives:</i> The current study aims to characterize qualitative feedback from the pilot participants about their experiences using the MBC system in SUD treatment, focusing on perceived benefits, drawbacks, and suggestions for improvement.<i>Methods:</i> Participants (<i>N</i> = 30; <i>n</i> = 11 female 37%) completed weekly MBC questionnaires via smartphone for 6 months and completed structured interviews at 6-, 12-, and 24-weeks. Themes were identified using a combination of inductive/deductive thematic analysis.<i>Results:</i> Participants highlighted several benefits of using the digital MBC system, including improved self-reflection (e.g. goal clarification, noticing changes over time), treatment enhancement (e.g. improving patient-clinician communication, extending the reach of treatment beyond scheduled sessions), and ease-of-use (e.g. brief, understandable questions). Drawbacks were less frequently expressed and included limited integration with clinical care, repetitiveness of questionnaires, and some questions being difficult to answer. Suggestions included making elements more personalized and improving interactivity with the digital interface.<i>Conclusion:</i> Patients report several benefits of integrating digitally delivered MBC into SUD treatment, along with recommendations that may improve its usability and usefulness. Integrating MBC technology into SUD treatment may potentially aid patients by enhancing self-reflection, facilitating more efficient communication with clinicians, and extending the reach of treatment beyond scheduled treatment sessions.</p>","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"317-327"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148687/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143494386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol administration in studies of human aggression: a methodological review.","authors":"Alexandra N Brockdorf, Amanda E Baildon, Sarah J Gervais, David DiLillo","doi":"10.1080/00952990.2025.2478391","DOIUrl":"10.1080/00952990.2025.2478391","url":null,"abstract":"<p><p><i>Background:</i> Alcohol administration paradigms are widely used to test the effects of alcohol on human aggression. However, methods used to implement alcohol administration designs can vary considerably, with implications for impact and generalizability.<i>Objectives:</i> This review summarizes and critically evaluates design features of alcohol administration studies on aggression to inform protocol development and provide recommendations for reporting practices.<i>Methods:</i> Ninety-seven studies that employed alcohol administration to study the effects of alcohol on interpersonal aggression were coded for methodological features, including the scope of aggressive behavior and sample characteristics, alcohol administration protocols, and elicitation of alcohol-related expectancies.<i>Results:</i> Alcohol administration studies of aggression have used relatively homogenous samples and aggression paradigms, especially laboratory analogues of alcohol-involved physical aggression. In the alcohol condition, researchers tended to induce relatively high intoxication (mean BrAC = 0.08) using a mixed liquor drink, though drinking and absorption periods relevant for breath alcohol concentration when aggression was assessed were less consistent. Almost all studies with a placebo condition (<i>n</i> = 65 out of 69) included beverage features to enhance alcohol-related expectancies and bolster believability, but only a third told placebo participants they received alcohol. Recommendations for reporting are presented in a checklist.<i>Conclusion:</i> This review identifies several future methodological directions, including greater inclusion of underrepresented individuals and types of aggression (e.g. sexual, intimate partner), consistent reporting of alcohol administration procedures, and evaluation of placebo enhancement strategies. Maximizing the rigor and replicability of these designs is essential for efforts to understand and reduce alcohol-related aggression.</p>","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"395-412"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategies to address co-occurring behavioral health needs among justice-involved youth.","authors":"Suhanee Mitragotri, Aakash Reddy, David T Zhu","doi":"10.1080/00952990.2025.2516680","DOIUrl":"10.1080/00952990.2025.2516680","url":null,"abstract":"","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"533-534"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nonfatal pediatric fentanyl exposures reported to US poison centers, 2015-2023.","authors":"Joseph J Palamar, Linda B Cottler, Joshua C Black","doi":"10.1080/00952990.2025.2457481","DOIUrl":"10.1080/00952990.2025.2457481","url":null,"abstract":"<p><p><i>Background:</i> The opioid crisis, driven by fentanyl use, continues to worsen in the US and there has been a lack of focus on nonfatal overdose and how pediatric populations are being affected.<i>Objectives:</i> We determined the prevalence of nonfatal pediatric fentanyl exposures and associated characteristics and delineated how such characteristics are associated with major (life-threatening) outcomes.<i>Methods:</i> This repeated cross-sectional study examined characteristics of pediatric nonfatal fentanyl exposures (aged 0-19 years) reported to poison centers in 49 US states from 2015 through 2023.<i>Results:</i> 3,009 nonfatal pediatric exposures (41.5% female) were reported to poison centers-58.9% aged 13-19 and 41.1% aged 0-12. The number of exposures increased overall from 69 in 2015 to 893 in 2023 (a 1,194.2% increase, <i>p</i> < .001). Exposures increased by 924.3% among those aged 0-12 (<i>p</i> < .001) and by 1,506.3% among those aged 13-19 (<i>p</i> < .001). Ingestion-only use was the most prevalent route of administration by those aged 0-12 (76.9%) and 13-19 (54.1%). Prevalence of ingestion-only use increased from 44.1% of exposures in 2015 to 67.9% in 2023 (<i>p</i> < .001). The majority of patients aged 0-12 were exposed unintentionally (81.7%, vs. 1.0% among patients aged 13-19) while the majority of patients aged 13-19 misused or \"abused\" fentanyl (65.7% vs. 1.8%). The plurality of exposures (41.0%) resulted in a major (life-threatening) effect.<i>Conclusions:</i> Pediatric exposures to fentanyl are increasing and over one-third of cases are unintentional and/or had documented life-threatening effects. Prevention and harm reduction efforts need to include efforts for youth, particularly as counterfeit pills containing fentanyl flood the illicit market.</p>","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"339-348"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12148699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of alternative income assistance disbursement on substance use disorder treatment adherence among people who use drugs.","authors":"Sukhpreet Klaire, JinCheol Choi, Allison Laing, Lindsey Richardson","doi":"10.1080/00952990.2025.2494112","DOIUrl":"10.1080/00952990.2025.2494112","url":null,"abstract":"<p><p><i>Background:</i> The synchronized disbursement of income assistance payments is associated with increased drug-related harms and substance use disorder (SUD) treatment interruptions. Desynchronizing and splitting these payments can mitigate escalations in drug use, suggesting that downstream effects on SUD treatment may be impacted as well.<i>Objectives:</i> To understand the effect of desynchronizing and splitting income assistance payments on treatment patterns, including adherence to medications for opioid use disorder (MOUD).<i>Methods:</i> Data came from The Impact of Alternative Social Assistance on Drug Related Harm (TASA) study, conducted in Vancouver, Canada. This parallel arm, multi-group, randomized controlled trial assigned participants for six payment cycles to the synchronized monthly government schedule control or one of two intervention arms receiving payments desynchronized from the government schedule: a \"staggered\" group receiving monthly payments or a \"split & staggered\" group receiving semimonthly payments. Multivariable generalized estimating equations assessed the effect on overall SUD treatment adherence, MOUD adherence, and non-MOUD SUD treatment adherence.<i>Results:</i> Between October 2015 and January 2019, 194 participants were randomized and followed, including 89 (45.8%) women and 83 (42.8%) who self-identified as a person of color. In both intent-to-treat (ITT) and modified per-protocol (MPP) analyses, neither intervention arm was associated with decreased adherence to SUD treatment (ITT staggered arm adjusted odds ratio [AOR] 0.75, 95% confidence interval [CI] 0.36-1.55, split and staggered arm AOR 0.83, 95% CI 0.44-1.57; MPP staggered arm AOR 0.72, 95% CI 0.38-1.39, split and staggered arm AOR 0.89, 95% CI 0.54-1.46), including MOUD and non-MOUD.<i>Conclusions:</i> Alternative income assistance disbursement did not positively impact SUD treatment adherence, contrary to the hypothesis. Changing payment schedules also did not negatively impact SUD treatment adherence, suggesting that changes to payment delivery could be completed without impacting treatment.</p>","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"383-394"},"PeriodicalIF":2.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}