American Journal of Drug and Alcohol Abuse最新文献_第10页

Racial and ethnic inequities in substance use treatment among women with opioid use disorder. 患有阿片类药物使用障碍的妇女在药物使用治疗方面的种族和民族不平等。

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2024-01-31 DOI: 10.1080/00952990.2023.2291748

Joy D Scheidell, Maya Pitre, Barbara Andraka-Christou

{"title":"Racial and ethnic inequities in substance use treatment among women with opioid use disorder.","authors":"Joy D Scheidell, Maya Pitre, Barbara Andraka-Christou","doi":"10.1080/00952990.2023.2291748","DOIUrl":"10.1080/00952990.2023.2291748","url":null,"abstract":"Background: Research describes inequities in substance use treatment, but few studies focus specifically on racial and ethnic disparities in a range of aspects of substance use treatment among women with opioid use disorder (OUD).Objective: To examine whether substance use treatment (i.e. receipt, sources, barriers) differs by race and ethnicity among women with opioid use disorder (OUD) and to identify factors associated with treatment gap (i.e. needing treatment but not receiving it).Methods: We performed cross-sectional analyses using National Survey on Drug Use and Health 2015-2019 data, restricted to non-Hispanic Black, non-Hispanic White, and Hispanic women with past-year OUD (unweighted n = 1089). We estimated the prevalence of aspects of treatment among racial and ethnic groups, and used modified Poisson regression to estimate correlates of reported treatment gap.Results: Approximately 68% of White versus 87% of Black and 81% of Hispanic women with OUD had a treatment gap (p-value 0.0034). Commonly reported barriers to treatment included prioritization, affordability, and stigma. Older age was associated with lower prevalence of treatment gap among all women [prevalence ratio (PR) = 0.83, and 95% confidence interval (CI): 0.76, 0.92], while criminal legal involvement and healthcare coverage was associated with a lower prevalence of treatment gap among Hispanic and White women only (past year arrest: Hispanic women PR = 0.38, 95% CI: 0.17, 0.86; White women PR = 0.62, 95% CI: 0.47, 0.82).Conclusions: Receipt of treatment is low among women with OUD, especially Black and Hispanic women. Intersectional intervention approaches are needed to increase access and reduce inequities.","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"106-116"},"PeriodicalIF":2.7,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139651989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expanding access to substance misuse services through emergency medical services: envisioning a novel partnership for addiction medicine clinicians. 通过紧急医疗服务扩大药物滥用服务的可及性：为成瘾医学临床医生设想一种新型合作关系。

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2024-01-11 DOI: 10.1080/00952990.2023.2286585

Nicholas M G Friedman, Matthew J Bivens

{"title":"Expanding access to substance misuse services through emergency medical services: envisioning a novel partnership for addiction medicine clinicians.","authors":"Nicholas M G Friedman, Matthew J Bivens","doi":"10.1080/00952990.2023.2286585","DOIUrl":"10.1080/00952990.2023.2286585","url":null,"abstract":"Emergency medical services (EMS) can be an invaluable ally of addiction medicine clinicians, but the potential role of EMS in combating the opioid epidemic has been under-realized. EMS has historically focused on emergency response and resuscitation in cases of overdose; however, EMS is also well-positioned to build rapport with persons who use drugs (PWUD), provide harm reduction services, and connect PWUD with additional treatment services and resources. A select number of EMS organizations have begun to offer substance-related programming that extends beyond resuscitation, but these offerings remain limited in scope and impact. This perspective argues that addiction medicine clinicians can bolster the ability of EMS to provide high quality substance-related services by engaging in prehospital care education, program development and research, and clinical care. This perspective shares practical strategies for addiction medicine clinicians to partner with EMS and considers several potential barriers that must be overcome, including bureaucratic challenges, variability in the scope of practice of EMS providers across different locations, and limited funding.","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"8-11"},"PeriodicalIF":2.7,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139425757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Opioid overdose after extended-release buprenorphine injection: a case report. 注射缓释丁丙诺啡后阿片类药物过量：病例报告。

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2024-01-22 DOI: 10.1080/00952990.2023.2292011

Raluca Isenberg

引用次数: 0

A scoping review of health inequities in alcohol use disorder. 对酒精使用障碍中的健康不平等现象进行范围界定。

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2024-01-31 DOI: 10.1080/00952990.2023.2296860

Shaelyn Ward, Josh Autaubo, Philo Waters, Elizabeth Garrett, Kelsi Batioja, Reece Anderson, Debra Furr-Holden, Matt Vassar

{"title":"A scoping review of health inequities in alcohol use disorder.","authors":"Shaelyn Ward, Josh Autaubo, Philo Waters, Elizabeth Garrett, Kelsi Batioja, Reece Anderson, Debra Furr-Holden, Matt Vassar","doi":"10.1080/00952990.2023.2296860","DOIUrl":"10.1080/00952990.2023.2296860","url":null,"abstract":"Background: Alcohol Use Disorder (AUD) poses a significant health burden on individuals. The burden occurs more frequently in the medically underserved, as well as racial and sexual minority populations. Ameliorating health inequities is vital to improving patient-centered care.Objectives: The objective of this scoping review is to chart the existing evidence on health inequities related to AUD and identify existing knowledge gaps to guide future equity-centered research.Methods: We performed a literature search using the Ovid (Embase) and MEDLINE (PubMed) databases for articles on AUD that were published in the 5-year period spanning from 2017 to 2021 and written in English. The frequencies of each health inequity examined were analyzed, and findings from each included study were summarized.Results: Our sample consisted of 55 studies for analysis. The most common inequity examined was by race/ethnicity followed by sex or gender. The least reported inequities examined were rural under-resourced areas and occupational status. Our findings indicate that significant research gaps exist in education, rural under-resourced populations, and LGBTQ+ communities with AUD.Conclusions: This scoping review highlights the gaps in research on inequities in AUD. To bridge the current gaps, we recommend research on the following: 1) triage screening tools and the use of telemedicine for rural, under-resourced populations; 2) interventions to increase treatment engagement and retention for women; and 3) community-based participatory methodologies for the LGBTQ+ communities.","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"27-41"},"PeriodicalIF":2.7,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139651985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cannabis cravings predict cigarette use in schizophrenia: a secondary analysis from two cannabis abstinence studies. 大麻渴求预测精神分裂症患者吸烟情况：对两项大麻戒断研究的二次分析。

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2024-01-12 DOI: 10.1080/00952990.2023.2292010

Samantha Johnstone, Maryam Sorkhou, Molly Zhang, Sarah S Dermody, Rachel A Rabin, Tony P George

引用次数: 0

GxE interaction effects of HCRTR2 single nucleotide polymorphism and adverse childhood experiences on methamphetamine use disorder. HCRTR2单核苷酸多态性和童年不良经历对甲基苯丙胺使用障碍的GxE交互效应。

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2024-01-31 DOI: 10.1080/00952990.2023.2297661

Kai-Ting Chen, Ming-Chyi Huang, Chun Lin, Hu-Ming Chang, Chung-Feng Kao

{"title":"GxE interaction effects of HCRTR2 single nucleotide polymorphism and adverse childhood experiences on methamphetamine use disorder.","authors":"Kai-Ting Chen, Ming-Chyi Huang, Chun Lin, Hu-Ming Chang, Chung-Feng Kao","doi":"10.1080/00952990.2023.2297661","DOIUrl":"10.1080/00952990.2023.2297661","url":null,"abstract":"Background: Methamphetamine use disorder (MUD) is a worldwide health concern. The hypothalamic orexin system regulates stress response and addictive behaviors. The genetic variation in the hypocretin receptor 2 (HCRTR2), rs2653349, is associated with substance use disorder.Objectives: We explored the gene-environment (GxE) interaction of rs2653349 and adverse childhood experiences (ACEs) associated with MUD susceptibility.Methods: Four hundred and one individuals (336 males, 65 females) with MUD and 348 healthy controls (288 males, 60 females) completed a self-report questionnaire evaluating ACEs, encompassing childhood abuse and household dysfunction categories, and were genotyped for SNP rs2653349. Methamphetamine use variables were collected using the Diagnostic Interview for Genetic Studies. We used regression analyses to assess the GxE effect on MUD risk.Results: The MUD group had a comparable genotypic distribution for rs2653349 to the control group, albeit with a higher prevalence and number of types of ACEs, correlating with an increased MUD risk (p < .05). No significant genetic impact of rs2653349 on MUD risk was found. However, we observed a GxE interaction effect between the minor allele of rs2653349 and the number of childhood abuse or household dysfunction types, correlating with a reduced MUD risk (OR = -0.71, p = .04, Benjamini-Hochberg adjusted p = .08 and OR = -0.59, p = .045, Benjamini-Hochberg adjusted p = .09, respectively).Conclusion: HCRTR2 SNP rs2653349 has no significant impact on MUD risk, but ACEs may increase this risk. GxE results suggest that rs2653349 could offer protection against developing MUD in individuals experiencing multiple types of ACEs.","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"84-94"},"PeriodicalIF":2.7,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139651987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of cannabis on non-medical opioid use among individuals receiving pharmacotherapies for opioid use disorder: a systematic review and meta-analysis of longitudinal studies. 大麻对接受阿片类药物使用障碍药物治疗者非医疗使用阿片类药物的影响：纵向研究的系统回顾和荟萃分析。

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2024-01-15 DOI: 10.1080/00952990.2023.2287406

Gabriel P A Costa, Julio C Nunes, Daniel L Heringer, Akhil Anand, Joao P De Aquino

{"title":"The impact of cannabis on non-medical opioid use among individuals receiving pharmacotherapies for opioid use disorder: a systematic review and meta-analysis of longitudinal studies.","authors":"Gabriel P A Costa, Julio C Nunes, Daniel L Heringer, Akhil Anand, Joao P De Aquino","doi":"10.1080/00952990.2023.2287406","DOIUrl":"10.1080/00952990.2023.2287406","url":null,"abstract":"Background: The relationship between cannabis use and the risk of returning to using opioids non-medically during treatment for opioid use disorder (OUD) remains unclear.Objective: We sought to quantify the impact of cannabis use on the risk of non-medical opioid use among people receiving pharmacotherapies for OUD.Methods: A comprehensive search was performed using multiple databases from March 1 to April 5 of 2023. Eligible studies longitudinally assessed the association between cannabis use and non-medical opioid use among people with OUD receiving treatment with buprenorphine, methadone, or naltrexone. We utilized a random-effects model employing the restricted maximum likelihood method. A sensitivity analysis was conducted to understand potential differences between each OUD treatment modality.Results: A total of 10 studies were included in the final meta-analysis. There were 8,367 participants (38% female). The average follow-up time across these studies was 9.7 months (SD = 3.77), ranging from 4 to 15 months. The pharmacotherapies involved were methadone (76.3%) buprenorphine (21.3%), and naltrexone (2.4%). The pooled odds ratio did not indicate that cannabis use significantly influenced non-medical opioid use (OR: 1.00, 95% CI: 0.97-1.04, p = .98). There is evidence of moderate heterogeneity and publication bias.Conclusion: There was no significant association between cannabis use and non-medical opioid use among patients receiving pharmacotherapies for OUD. These findings neither confirm concerns about cannabis increasing non-medical opioid use during MOUD, nor do they endorse its efficacy in decreasing non-medical opioid use with MOUD. This indicates a need for individualized approaches for cannabis use and challenges the requirement of cannabis abstinence to maintain OUD pharmacotherapies.","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"12-26"},"PeriodicalIF":2.7,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139472993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Are you thinking what I'm thinking? Defining what we mean by "polysubstance use." 你在想我在想的事吗？定义我们所说的“多物质使用”

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2023-09-21 DOI: 10.1080/00952990.2023.2248360

Amanda M Bunting, Riley Shearer, Ashley N Linden-Carmichael, Arthur Robin Williams, Sandra D Comer, Magdalena Cerdá, Jennifer Lorvick

{"title":"Are you thinking what I'm thinking? Defining what we mean by \"polysubstance use.\"","authors":"Amanda M Bunting, Riley Shearer, Ashley N Linden-Carmichael, Arthur Robin Williams, Sandra D Comer, Magdalena Cerdá, Jennifer Lorvick","doi":"10.1080/00952990.2023.2248360","DOIUrl":"10.1080/00952990.2023.2248360","url":null,"abstract":"The rise in drug overdoses and harms associated with the use of more than one substance has led to increased use of the term \"polysubstance use\" among researchers, clinicians, and public health officials. However, the term retains no consistent definition across contexts. The current authors convened from disciplines including sociology, epidemiology, neuroscience, and addiction psychiatry to propose a recommended definition of polysubstance use. An iterative process considered authors' formal and informal conversations, insights from relevant symposia, talks, and conferences, as well as their own research and clinical experiences to propose the current definition. Three key concepts were identified as necessary to define polysubstance use: (1) substances involved, (2) timing, and (3) intent. Substances involved include clarifying either (1) the number and type of substances used, (2) presence of more than one substance use disorder, or (3) primary and secondary substance use. The concept of timing is recommended to use clear terms such as simultaneous, sequential, and same-day polysubstance use to describe short-term behaviors (e.g., 30-day windows). Finally, the concept of intent refers to clarifying unintentional use or exposure when possible, and greater attention to motivations of polysubstance use. These three components should be clearly defined in research on polysubstance use to improve consistency across disciplines. Consistent definitions of polysubstance use can aid in the synthesis of evidence to better address an overdose crisis that increasingly involves multiple substances.","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"1-7"},"PeriodicalIF":2.7,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10939915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41154068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of fisetin on ethanol-induced rewarding properties in mice. 鱼腥草素对乙醇诱导的小鼠奖赏特性的影响

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2024-01-18 DOI: 10.1080/00952990.2023.2292976

Yasin Yalniz, Oruç Yunusoğlu, Mehmet Berköz, Mustafa Enes Demirel

{"title":"Effects of fisetin on ethanol-induced rewarding properties in mice.","authors":"Yasin Yalniz, Oruç Yunusoğlu, Mehmet Berköz, Mustafa Enes Demirel","doi":"10.1080/00952990.2023.2292976","DOIUrl":"10.1080/00952990.2023.2292976","url":null,"abstract":"Background: Alcohol use disorder (AUD) is a chronic relapsing disorder associated with compulsive drinking of alcohol. Natural flavonoid fisetin affects a variety of transmitter systems relevant to AUD, such as aminobutyric acid, N-methyl-D-aspartate, and dopamine, as well as peroxisome proliferator-activated receptors.Objectives: This study investigated fisetin's impact on the motivational properties of ethanol using conditioned place preference (CPP) in mice (n = 50).Methods: Mice were conditioned with ethanol (2 g/kg, i.p.) or saline on alternating days for 8 consecutive days and were given intragastric (i.g.) fisetin (10, 20, or 30 mg/kg, i.g.), 45 min before ethanol conditioning. During extinction, physiological saline was injected to the control and ethanol groups, and fisetin was administered to the fisetin groups. To evaluate the effect of fisetin on the reinstatement of ethanol-induced CPP, fisetin was given 45 min before a priming dose of ethanol (0.4 g/kg, i.p.; reinstatement test day).Results: Fisetin decreased the acquisition of ethanol-induced CPP (30 mg/kg, p < .05) and accelerated extinction (20 and 30 mg/kg, p < .05). Furthermore, fisetin attenuated reinstatement of ethanol-induced CPP (30 mg/kg, p < .05).Conclusions: Fisetin appears to diminish the rewarding properties of ethanol, as indicated by its inhibitory effect and facilitation of extinction in ethanol-induced CPP. These findings imply a potential therapeutic application of fisetin in preventing ethanol-seeking behavior, promoting extinction, and reducing the risk of relapse.","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"75-83"},"PeriodicalIF":2.7,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139486570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fiduciary assignment as a potential intervention for substance use disorder: a retrospective chart review. 信托分配作为一种潜在的药物使用障碍干预措施：回顾性病历审查。

IF 2.7 3区医学

American Journal of Drug and Alcohol Abuse Pub Date : 2024-01-02 Epub Date: 2024-02-01 DOI: 10.1080/00952990.2023.2286584

Amanda von Horn, David Hathaway, Janet Richmond, Grace Chang

{"title":"Fiduciary assignment as a potential intervention for substance use disorder: a retrospective chart review.","authors":"Amanda von Horn, David Hathaway, Janet Richmond, Grace Chang","doi":"10.1080/00952990.2023.2286584","DOIUrl":"10.1080/00952990.2023.2286584","url":null,"abstract":"Background: Assignment of fiduciaries to veterans with disability payments is an intervention thought to improve quality of life; however, in veterans who use substances, a proportion of these payments may be misspent on drugs and/or alcohol. While fiduciary assignment may reduce funds available to purchase substances, clinical efficacy of this intervention in the management of substance use disorders has not been rigorously demonstrated.Objectives: The purpose of this study is to evaluate changes in clinical status before and after fiduciary assignment.Methods: This was a retrospective chart review of 50 (44 male, 6 female) veterans who were assigned a fiduciary and determined to have a substance use disorder (SUD). SUD-related data including outpatient and inpatient treatment, toxicology testing, and measures of psychosocial functioning for the three years before and after fiduciary assignment were extracted and compared.Results: Veterans were found to have higher rates of any form of employment after fiduciary assignment (Wilcoxon, Signed Ranked S-statistic = 0.22, pr = 0.02). Two changes in measures of substance use were found after fiduciary assignment. There was a reduction in positive screens for heroin (tstatistic = -2.7, p = .01), but an increase in positive screens for fentanyl (t statistic = 2.53, p = .02). There were some potentially clinically but not statistically significant trends in increased adherence with mental health appointments, number of medical hospitalizations, and rates of employment post-fiduciary assignment.Conclusions: Understanding the clinical impact of fiduciary assignment for veteran's benefits is desirable but still pending at this time.","PeriodicalId":48957,"journal":{"name":"American Journal of Drug and Alcohol Abuse","volume":" ","pages":"117-122"},"PeriodicalIF":2.7,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139651986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0