Alcohol administration in studies of human aggression: a methodological review.

IF 2.7 3区 医学 Q2 PSYCHOLOGY, CLINICAL
Alexandra N Brockdorf, Amanda E Baildon, Sarah J Gervais, David DiLillo
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Abstract

Background: Alcohol administration paradigms are widely used to test the effects of alcohol on human aggression. However, methods used to implement alcohol administration designs can vary considerably, with implications for impact and generalizability.Objectives: This review summarizes and critically evaluates design features of alcohol administration studies on aggression to inform protocol development and provide recommendations for reporting practices.Methods: Ninety-seven studies that employed alcohol administration to study the effects of alcohol on interpersonal aggression were coded for methodological features, including the scope of aggressive behavior and sample characteristics, alcohol administration protocols, and elicitation of alcohol-related expectancies.Results: Alcohol administration studies of aggression have used relatively homogenous samples and aggression paradigms, especially laboratory analogues of alcohol-involved physical aggression. In the alcohol condition, researchers tended to induce relatively high intoxication (mean BrAC = 0.08) using a mixed liquor drink, though drinking and absorption periods relevant for breath alcohol concentration when aggression was assessed were less consistent. Almost all studies with a placebo condition (n = 65 out of 69) included beverage features to enhance alcohol-related expectancies and bolster believability, but only a third told placebo participants they received alcohol. Recommendations for reporting are presented in a checklist.Conclusion: This review identifies several future methodological directions, including greater inclusion of underrepresented individuals and types of aggression (e.g. sexual, intimate partner), consistent reporting of alcohol administration procedures, and evaluation of placebo enhancement strategies. Maximizing the rigor and replicability of these designs is essential for efforts to understand and reduce alcohol-related aggression.

酒精在人类攻击研究中的应用:方法学回顾
背景:酒精管理范式被广泛用于测试酒精对人类攻击性的影响。然而,用于实施酒精管理设计的方法可能有很大的不同,这对影响和普遍性有影响。目的:本综述总结并批判性地评价了酒精给药研究中攻击行为的设计特点,为方案制定提供信息,并为报告实践提供建议。方法:97项使用酒精管理来研究酒精对人际攻击的影响的研究,根据方法特征进行编码,包括攻击行为的范围和样本特征、酒精管理方案和酒精相关期望的引发。结果:酒精给药对攻击的研究使用了相对同质的样本和攻击范式,尤其是酒精相关身体攻击的实验室类似物。在酒精条件下,研究人员倾向于使用混合酒精饮料诱导相对较高的中毒(平均BrAC = 0.08),尽管在评估攻击性时,与呼吸酒精浓度相关的饮酒和吸收时间不太一致。几乎所有在安慰剂条件下的研究(69项研究中有65项)都包括饮料特征,以提高与酒精相关的预期,增强可信度,但只有三分之一的研究告诉安慰剂参与者他们喝了酒。报告的建议列在清单中。结论:本综述确定了未来的几个方法学方向,包括更多地纳入代表性不足的个体和攻击类型(如性攻击、亲密伴侣攻击),一致报告酒精管理程序,以及评估安慰剂增强策略。最大限度地提高这些设计的严谨性和可复制性对于理解和减少与酒精有关的攻击行为至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.70
自引率
3.70%
发文量
68
期刊介绍: The American Journal of Drug and Alcohol Abuse (AJDAA) is an international journal published six times per year and provides an important and stimulating venue for the exchange of ideas between the researchers working in diverse areas, including public policy, epidemiology, neurobiology, and the treatment of addictive disorders. AJDAA includes a wide range of translational research, covering preclinical and clinical aspects of the field. AJDAA covers these topics with focused data presentations and authoritative reviews of timely developments in our field. Manuscripts exploring addictions other than substance use disorders are encouraged. Reviews and Perspectives of emerging fields are given priority consideration. Areas of particular interest include: public health policy; novel research methodologies; human and animal pharmacology; human translational studies, including neuroimaging; pharmacological and behavioral treatments; new modalities of care; molecular and family genetic studies; medicinal use of substances traditionally considered substances of abuse.
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