{"title":"A pathological lesion or a postmortem artefact? An interdisciplinary approach to deal with an interesting early medieval case","authors":"Martina Fojtová , Jan Křístek , Lukáš Kučera","doi":"10.1016/j.ijpp.2023.10.003","DOIUrl":"10.1016/j.ijpp.2023.10.003","url":null,"abstract":"<div><h3>Objective</h3><p>This study evaluates a case of pseudopathology and the effects that postmortem taphonomic changes and environmental influences can have on bone.</p></div><div><h3>Material</h3><p>A skeleton of a young male from the early medieval site Staré Město, dated to the 9th–10th century CE.</p></div><div><h3>Methods</h3><p><span>The skeletal remains were subjected to detailed macroscopic and X-ray examination, and then a CT scan and </span>XRF analysis were performed.</p></div><div><h3>Results</h3><p><span>X-ray examination of the mandible revealed unusually dense structures, whose appearance was not consistent with any known pathology. Based on the results of CT scanning, it was hypothesized that these were cavities filled with </span>alluvial sediment. X-ray fluorescence spectrometry (XRF), focusing on the determination of the silica content, revealed a high intensity of silica in the samples of the affected area of the bone.</p></div><div><h3>Conclusion</h3><p>The hypothesis that the inclusions were composed of waterborne sediment was supported.</p></div><div><h3>Significance</h3><p>Although it is well known that soil can infiltrate bones buried in the ground, its appearance on plain radiographs is not that commonly known. The case illustrates the usefulness of differentiating true pathologies from postmortem alterations to avoid inappropriate interpretations.</p></div><div><h3>Limitations</h3><p>No similar cases have been described.</p></div><div><h3>Suggestion for further research</h3><p>In palaeopathological evaluation, the use of multiple imaging and evaluative techniques should be implemented to differentiate pathological lesions from pseudopathology.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 93-98"},"PeriodicalIF":1.2,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71430524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gretchen R. Dabbs , Anna Stevens , Melinda King Wetzel
{"title":"A mature ovarian teratoma from New Kingdom Amarna, Egypt","authors":"Gretchen R. Dabbs , Anna Stevens , Melinda King Wetzel","doi":"10.1016/j.ijpp.2023.10.004","DOIUrl":"10.1016/j.ijpp.2023.10.004","url":null,"abstract":"<div><h3>Objective</h3><p>This paper describes the fifth case of a mature ovarian teratoma reported in the bioarchaeological literature, contributing to the temporal and geographical distribution of known examples of this unusual pathology.</p></div><div><h3>Materials</h3><p>An 18–21-year-old female found in situ within a multi-chambered subterranean tomb in the North Desert Cemetery at Amarna, Egypt (founded c. 1345 BCE) was recovered associated with a multi-lobed roughly ovoid calcified mass and two associated teeth identified within the pelvic cavity.</p></div><div><h3>Methods</h3><p>Macroscopic evaluation alongside careful differential diagnosis.</p></div><div><h3>Conclusions</h3><p>The presence of multiple teeth and their degree of development provided sufficient evidence to identify this mass as an ovarian teratoma found in association with a young woman buried in one of the most richly adorned burials in the non-elite cemeteries at the New Kingdom site of Amarna. The teratoma is interpreted within our understanding of the broader social context of ancient Egyptian medical knowledge.</p></div><div><h3>Significance</h3><p>This case is the only reported example of a mature ovarian teratoma from Pharaonic Egypt, and Africa more broadly, predating other reported cases by several centuries. It adds considerable temporal and geographical depth to our understanding of this condition in the past.</p></div><div><h3>Limitations</h3><p>This study was limited to macroscopic examination of remains and would likely benefit from either x-ray or CT-scanning of the object to examine the internal structure.</p></div><div><h3>Suggestions for Further Research</h3><p>Further consideration of the likely physical implications of this pathology, along with the broader social aspects of burial with objects of potential magico-medical significance is necessary.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 99-105"},"PeriodicalIF":1.2,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71430523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The palaeopathology of industry, a perspective from Britain","authors":"S.A. Mays","doi":"10.1016/j.ijpp.2023.10.001","DOIUrl":"10.1016/j.ijpp.2023.10.001","url":null,"abstract":"<div><h3>Objectives</h3><p>This article considers the position of palaeopathology of ca. 1750AD onward within the subdiscipline of Industrial Archaeology, and reflects upon the relationship between skeletal palaeopathology and textual sources on disease prevalences.</p></div><div><h3>Methods</h3><p>It draws upon the author’s experience in engaging with threat-led archaeology. It synthesises key elements of palaeopathological literature, emphasising contributions to the IJPP VSI ‘Changes in Health with the Rise of Industry’, and also the broader literature regarding Industrial Archaeology.</p></div><div><h3>Results</h3><p>Industrial Archaeology has seen a recent refocus to include not only a concentration upon technological aspects of industry but also increased emphasis the social context of industrialisation. This movement toward a placement of people as well as machines centre stage has resulted in an environment conducive for paleopathology to make a greater impact upon studies of the period.</p></div><div><h3>Conclusions</h3><p>Palaeopathologists need to ensure that their biocultural work is orientated toward research goals of broader relevance if the impact of their work is to be maximised. We cannot directly align prevalence data generated from skeletal and and written sources; roles played by these two sources of evidence will depend, <em>inter alia</em>, upon the problems being investigated.</p></div><div><h3>Significance</h3><p>The success of ‘Industrial Palaeopathology’ will be measured by the extent to which human remains studies move toward centre stage within the broader discipline of Industrial Archaeology.</p></div><div><h3>Limitations</h3><p>Multiple perspectives on disciplinary development are possible. Academic traditions, relationships between university- and threat led-sectors, and the opportunities and challenges engendered by working with human remains, differ in different countries.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 85-92"},"PeriodicalIF":1.2,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1879981723000578/pdfft?md5=dc44ddce5553d50376109f375ca12dbf&pid=1-s2.0-S1879981723000578-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61566997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monika Schernig-Mráz , Anne L. Grauer , Gottfried Morgenegg
{"title":"Dental health in Roman dogs: A pilot study using standardized examination methods","authors":"Monika Schernig-Mráz , Anne L. Grauer , Gottfried Morgenegg","doi":"10.1016/j.ijpp.2023.09.007","DOIUrl":"10.1016/j.ijpp.2023.09.007","url":null,"abstract":"<div><h3>Objective</h3><p>To utilize standardized clinical veterinary methods to analyze dental health in a series of Roman dog maxillae and mandibles and to compare results to modern clinical data.</p></div><div><h3>Materials</h3><p>28 skulls of juvenile and adult dogs from three archaeological sites in Switzerland and Germany dating to the Roman period.</p></div><div><h3>Methods</h3><p>Standardized examination was carried out, which included metric radiographic assessment to diagnose oral pathology and estimate age at death. In one case, CT analysis was undertaken.</p></div><div><h3>Results</h3><p>The estimated average age at death was between three and four years old. Tooth fracture, periodontal disease, the presence of non-vital teeth, and brachycephalic skull form were found in the sample. Tooth resorption was unexpectedly noted.</p></div><div><h3>Conclusion</h3><p>The study provides valuable insights into the dental health of dogs in the Roman era. Compared to modern dogs, Roman dogs examined in this study appear to have a shorter lifespan but display a high rate of pathological dental disease, while disease patterns were very similar to those of modern dogs. Dogs with pronounced brachycephalic features were found.</p></div><div><h3>Significance</h3><p>This pilot study is the first to use standardized clinical examination and recording techniques to assess dental health in dogs from archaeological contexts. It provides insight into the dental health of Roman era dogs and offers data upon which cross-populational studies can be initiated.</p></div><div><h3>Limitations</h3><p>The sample size and geographic location of the archaeological sites were limited.</p></div><div><h3>Suggestions for further research</h3><p>Subsequent standardized studies, preferably in as many different Roman Empire regions as possible, are recommended.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 72-84"},"PeriodicalIF":1.2,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Observer agreement on the morphology of porous cranial lesions: Results from a workshop at the 2019 meeting of the Paleopathology Association","authors":"Amy S. Anderson","doi":"10.1016/j.ijpp.2023.09.006","DOIUrl":"10.1016/j.ijpp.2023.09.006","url":null,"abstract":"<div><h3>Objective</h3><p>This paper presents the results of a 2019 Paleopathology Association workshop that tested observer agreement on porous cranial lesion morphology and presence using multiple sets of existing guidelines for data collection.</p></div><div><h3>Materials</h3><p>Sixteen conference attendees of varying osteological experience served as observers. Three crania were assigned to each of four published guidelines for identifying and categorizing lesion morphology, for a total of twelve well-preserved human crania from the National Museum<span> of Natural History Biological Anthropology Collections.</span></p></div><div><h3>Methods</h3><p>Observers assessed each cranium macroscopically according to its assigned set of guidelines.</p></div><div><h3>Results</h3><p>Observer concordance was higher using scoring guidelines with higher-quality photographs, such as the 2019 guidelines from Rinaldo and colleagues.</p></div><div><h3>Conclusions</h3><p>Data collection guidelines with high-quality color photos may support greater reliability of researcher-generated data on macroscopic skeletal features.</p></div><div><h3>Significance</h3><p>The conclusions of any research study are only as reliable as the data on which they are based. This work highlights the need for ongoing practices of quality control in a field in which much data results from individual judgement calls.</p></div><div><h3>Limitations</h3><p>Observer concordance is not a measure of observer accuracy. Sample size is insufficient to draw broadly generalizable conclusions on the reliability of data collected using the guidelines tested, and conference environments are not a facsimile of research settings.</p></div><div><h3>Suggestions for further research</h3><p>Iterative testing of methodological consistency using larger sample sizes and more non-pathological crania is advised to identify the factors that influence observer discordance and to improve guidelines for qualitative assessments.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 68-71"},"PeriodicalIF":1.2,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41167585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanical stress in the urbanized Roman Phoenician coast","authors":"Mahmoud Mardini , Ali Badawi , Tania Zaven , Raffi Gergian , Efthymia Nikita","doi":"10.1016/j.ijpp.2023.09.008","DOIUrl":"10.1016/j.ijpp.2023.09.008","url":null,"abstract":"<div><h3>Objective</h3><p>Skeletal populations from Byblos, Beirut, and Tyre were studied to assess mechanical stress along the Roman Phoenician coast.</p></div><div><h3>Materials</h3><p>The sample included 153 adult skeletons.</p></div><div><h3>Methods</h3><p>Skeletal remains were macroscopically assessed for osteoarthritis<span>, intervertebral disc disease (IDD), and Schmorl’s nodes.</span></p></div><div><h3>Results</h3><p>The Byblos population experienced higher levels of mechanical stress than the Beirut and Tyre ones. Sex-based differences were also found in all skeletal assemblages with males likely engaging in physically more demanding tasks.</p></div><div><h3>Conclusions</h3><p>The variation in mechanical stress, and associated physically demanding tasks, between these populations can be attributed to their differing political and economic status during the Roman period; textual sources highlight the economic and political dominance of Beirut and Tyre, emanating from their status as <em>coloniae</em>.</p></div><div><h3>Significance</h3><p>This study represents one of the first attempts to investigate mechanical stress in coastal Phoenicia during the Roman period. It provides valuable insights into the biocultural structure of understudied communities at the periphery of the Roman world, and can serve as a basis for further future research into the occupational patterns of Phoenician communities.</p></div><div><h3>Limitations</h3><p>The contextual information for these skeletal populations is very limited and does not allow secure conclusions regarding their representativeness. The sample sizes are also rather small, especially when divided per sex and age.</p></div><div><h3>Suggestions for Further Research</h3><p>Further investigation employing complementary methods such as cross-sectional geometric properties and entheseal changes is needed to reconstruct the occupational patterns of these communities, taking into account cultural, environmental, and temporal factors.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 58-67"},"PeriodicalIF":1.2,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41169302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of secondary hypertrophic osteoarthropathy from medieval Tuscany (central Italy, 10th-12th centuries CE)","authors":"Valentina Giuffra , Simona Minozzi , Giacomo Aringhieri , Stefano Campana , Giulia Riccomi","doi":"10.1016/j.ijpp.2023.09.004","DOIUrl":"10.1016/j.ijpp.2023.09.004","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aims to provide a detailed evaluation of a case of secondary hypertrophic osteoarthropathy (HOA) and to explore insights into the presence and consequences of disease in medieval rural Italy.</p></div><div><h3>Materials</h3><p>The skeleton of a male (US 4405) with an estimated age at death of 51–69 years excavated from the medieval rural site of Pieve di Pava (Siena, Italy).</p></div><div><h3>Methods</h3><p>Macroscopic and radiological (x-ray, CT) analyses were performed.</p></div><div><h3>Results</h3><p>Symmetrical extensive periosteal new bone formation on the diaphyseal and metaphyseal regions of this individual’s long bones; the lower limbs were more extensively and severely affected than the upper limbs and the distal segments were more severely altered in comparison to the proximal ones.</p></div><div><h3>Conclusions</h3><p>The macroscopic and radiological features are highly consistent with a diagnosis of secondary HOA.</p></div><div><h3>Significance</h3><p>The excellent state of preservation allowed the evaluation of rarely noted skeletal manifestations of HOA and provided insight into aspects of rural life in medieval Italy.</p></div><div><h3>Limitations</h3><p>Molecular analysis was not successful in sequencing the aDNA of tuberculosis, therefore the underlying primary cause of secondary HOA, whether pulmonary or extrapulmonary, remains obscure in this case.</p></div><div><h3>Suggestion for the future research</h3><p>It is advisable to regularly revisit the data available from osteoarchaeological collections in order to identify further cases of HOA, along with to further investigate the known cases to search for the underlying primary disease.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 51-57"},"PeriodicalIF":1.2,"publicationDate":"2023-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41180734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramón López-Gijón , Edgard Camarós , Ángel Rubio-Salvador , Salvatore Duras , Miguel C. Botella-López , Inmaculada Alemán-Aguilera , Ángel Rodríguez-Aguilera , Macarena Bustamante-Álvarez , Lydia P. Sánchez-Barba , Benjamin Dufour , Matthieu Le Bailly
{"title":"Implications of the prevalence of Ascaris sp. in the funerary context of a Late Antique population (5th-7th c.) in Granada (Spain)","authors":"Ramón López-Gijón , Edgard Camarós , Ángel Rubio-Salvador , Salvatore Duras , Miguel C. Botella-López , Inmaculada Alemán-Aguilera , Ángel Rodríguez-Aguilera , Macarena Bustamante-Álvarez , Lydia P. Sánchez-Barba , Benjamin Dufour , Matthieu Le Bailly","doi":"10.1016/j.ijpp.2023.09.002","DOIUrl":"10.1016/j.ijpp.2023.09.002","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the prevalence of gastro-intestinal parasites in human remains from Late Antiquity (5th – 7th c.) Granada (Spain).</p></div><div><h3>Materials</h3><p>The study included pelvic and cranial control samples from 17 skeletons from the archaeological sites of Los Mondragones (n = 13) and Rafael Guillén (n = 4).</p></div><div><h3>Methods</h3><p>In the paleoparasitological study, soil samples from pelvic area and cranium were analyzed using the rehydration, homogenization, and micro-sieving method and visualization under brightfield microscopy.</p></div><div><h3>Results</h3><p><em>Ascaris</em> sp. eggs were detected in pelvic samples from seven individuals.</p></div><div><h3>Conclusions</h3><p>These findings may indicate that this parasite was endemic. Its detection frequency is one of the highest reported at group level in an osteological series from Late Antiquity.</p></div><div><h3>Significance</h3><p>The prevalence of <em>Ascaris</em> sp. associated with skeletal remains has implications for assessing the lifestyle and health of populations in southern Spain during the Late Antique period.</p></div><div><h3>Limitations</h3><p>The number of individuals is small and taphonomic processes could have limited paleoparasitological findings</p></div><div><h3>Suggestions for further research</h3><p>Future interdisciplinary studies of this type are warranted in larger osteological series to improve knowledge of parasitosis in the past.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 45-50"},"PeriodicalIF":1.2,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41165294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Á. Rubio Salvador , L.P. Sánchez-Barba , J. Úbeda-Portugués , A. Martín-Prats , J. Vélez , J. Irurita , I. Alemán
{"title":"Trepanations in non-adults of the 16th to 18th C. The osteological series of the Church of the Assumption of Valdepeñas (Ciudad Real, Spain)","authors":"Á. Rubio Salvador , L.P. Sánchez-Barba , J. Úbeda-Portugués , A. Martín-Prats , J. Vélez , J. Irurita , I. Alemán","doi":"10.1016/j.ijpp.2023.09.005","DOIUrl":"10.1016/j.ijpp.2023.09.005","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the presence of trepanations in an early Modern Age, skeletal collection documented in medical treatises but infrequently reported in osteological collections.</p></div><div><h3>Materials</h3><p>Analyses were conducted on 387 non-adult crania from the ossuary in the church of the Assumption of Valdepeñas (16th - 18th C.), Ciudad Real, Spain.</p></div><div><h3>Methods</h3><p>All complete or semi-complete crania of non-adults (aged 3–20 years) were macroscopically examined.</p></div><div><h3>Results</h3><p>Trepanation was detected in two adolescents aged 14 and 20 years; no evidence of their survival was observed.</p></div><div><h3>Conclusions</h3><p>These findings suggest that trepanation was carried out in rural areas as Valdepeñas in the 16th-18th centuries, where the selection of instruments indicates knowledge of contemporaneous medical treatises.</p></div><div><h3>Significance</h3><p>The present study provides new data on trepanation and how it was performed in adolescents during this period.</p></div><div><h3>Limitations</h3><p>Understanding the motive for these interventions is highly challenging in the absence of bone lesions, and their occurrence is likely underestimated due to the scant research in skeletal remains from the early Modern Age.</p></div><div><h3>Suggestions for future research</h3><p>Further palaeopathological analyses of osteological collections from this period will provide more information about how this surgical technique was perfected.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 37-44"},"PeriodicalIF":1.2,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41155868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differential diagnosis of a calcified object from the South Tombs Cemetery at Amarna, Egypt","authors":"Gretchen R. Dabbs","doi":"10.1016/j.ijpp.2023.09.001","DOIUrl":"10.1016/j.ijpp.2023.09.001","url":null,"abstract":"<div><h3>Objective</h3><p>This paper provides a brief history of the publication of calcified biological objects and presents one that was present in the grave associated with a mature adult female buried in the South Tombs Cemetery at Amarna, Egypt (c. 1353–1332BCE).</p></div><div><h3>Methods</h3><p><span>Macroscopic examination revealed an ovoid object constructed of concentric layers of a coarse sand-like material oriented around a dense core that lacked evidence of parasites. Microscopic examination revealed the object is composed of densely, yet haphazardly packed, elongated octahedron shaped crystals with no evidence of cellular structures. Basic chemical analysis eliminated </span>calcium carbonate as a constituent material.</p></div><div><h3>Results</h3><p>Based on comparison with previously published examples from the archaeological and clinical literature and careful differential diagnosis, it is suggested this object is a bladder stone.</p></div><div><h3>Significance</h3><p>A brief discussion of the implications of bladder stones on individual health and broader epidemiological constraints to illustrate the depth such discoveries can bring to our understanding of ancient lived experience concludes the work.</p></div><div><h3>Limitations</h3><p>The burial of Ind. 286 was disturbed. The identification of a bladder stone presumes the stone would have been found within the pelvic cavity, which cannot be confirmed. Other graves in the vicinity of this grave were also disturbed. It is unlikely, but still possible, that the stone originated from another grave and was relocated to this grave after disturbance. Full chemical analysis was not possible.</p></div><div><h3>Suggestions for future research</h3><p>Radiographic and chemical analysis would provide more information to strengthen the certainty of the differential diagnosis.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"43 ","pages":"Pages 31-36"},"PeriodicalIF":1.2,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41126097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}