Brianne Morgan , Karanvir Prakash , John C. Mayberry , Megan B. Brickley
{"title":"Thoracic trauma: Clinical and paleopathological perspectives","authors":"Brianne Morgan , Karanvir Prakash , John C. Mayberry , Megan B. Brickley","doi":"10.1016/j.ijpp.2022.09.003","DOIUrl":"10.1016/j.ijpp.2022.09.003","url":null,"abstract":"<div><h3>Objectives</h3><p>Although trauma is one of the most significant areas of study in paleopathology, most studies focus on fractures of single anatomical elements. Paleopathological research on regional trauma, such as of the thorax, is rare. This paper explores the causes, complications, and consequences of adult thoracic trauma using clinical data in order to inform paleopathological research.</p></div><div><h3>Materials and methods</h3><p>Trends in paleopathological thoracic trauma literature were assessed by evaluating publications from Bioarchaeology International, International Journal of Osteoarchaeology, International Journal of Paleopathology, and American Journal of Biological Anthropology. Clinical publications on thoracic trauma throughout time were also assessed through a PubMed search, and modern prevalence data was found through trauma databases such as the National Trauma Databank.</p></div><div><h3>Results</h3><p>Consideration of thoracic trauma involving concomitant injuries is a recent trend in clinical literature and patient care, but paleopathological research on thoracic trauma has been limited. Since thoracic fractures tend to occur in conjunction with other injuries, assessing them together is critical to the interpretation of trauma in the past.</p></div><div><h3>Conclusions</h3><p>Clinical research into thoracic fractures and concomitant injuries provides valuable data for paleopathological research. Evaluating the likelihood and consequences of concomitant injury in skeletal remains provides a more robust understanding of trauma in the past and its impact on past lifeways.</p></div><div><h3>Significance</h3><p>This paper provides a review of current clinical and paleopathological literature on thoracic trauma and demonstrates the importance of moving beyond the analysis of fractures or trauma of single anatomical elements.</p></div><div><h3>Limitations</h3><p>Thoracic bones are often taphonomically altered and differentially preserved leading to difficulty in identifying and interpreting fractures.</p></div><div><h3>Suggestions for Further Research</h3><p>Practical application of the data presented here to archaeological samples will help to advance paleopathological understandings of thoracic trauma.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 50-63"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10395308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tianyi Wang , Craig Cessford , Jenna M. Dittmar , Sarah Inskip , Peter M. Jones , Piers D. Mitchell
{"title":"Intestinal parasite infection in the Augustinian friars and general population of medieval Cambridge, UK","authors":"Tianyi Wang , Craig Cessford , Jenna M. Dittmar , Sarah Inskip , Peter M. Jones , Piers D. Mitchell","doi":"10.1016/j.ijpp.2022.06.001","DOIUrl":"10.1016/j.ijpp.2022.06.001","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate how lifestyle may have impacted the risk of contracting intestinal parasites in medieval England . Regular clergy (such as those living in monasteries) and the lay population form interesting groups for comparison as diet and lifestyle varied significantly. Monasteries were built with latrine blocks and hand washing facilities, unlike houses of the poor.</p></div><div><h3>Materials</h3><p>Sediment samples from the pelvis, along with control samples from feet and skull, of 19 burials of Augustinian Friars (13th-16th century), and 25 burials from All Saints by the Castle parish cemetery (10th-14th century), Cambridge.</p></div><div><h3>Methods</h3><p>We analysed the sediment using micro-sieving and digital light microscopy to identify the eggs of intestinal parasites.</p></div><div><h3>Results</h3><p>Parasite prevalence (roundworm and whipworm) in the Augustinian friars was 58%, and in the All Saints by the Castle parishioners just 32% (Barnards Test score statistic 1.7176, p-value 0.092).</p></div><div><h3>Conclusions</h3><p>It is interesting that the friars had nearly double the infection rate of parasites spread by poor hygiene, compared with the general population. We consider options that might explain this difference, and discuss descriptions and treatment of intestinal worms in medical texts circulating in Cambridge during the medieval period.</p></div><div><h3>Significance</h3><p>This is the first study to compare prevalence of parasite infection between groups with different socioeconomic status from the same location.</p></div><div><h3>Limitations</h3><p>Quality of egg preservation was suboptimal, so our data may under-represent the true prevalence.</p></div><div><h3>Suggestions for further research</h3><p>Larger studies with greater statistical power, covering different time periods and regions.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 115-121"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1879981722000316/pdfft?md5=b35aee62418703a68886fe0456c5c2df&pid=1-s2.0-S1879981722000316-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10395966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruggero D’Anastasio, Francesca Monza, Jacopo Cilli, Luigi Capasso
{"title":"Generalized dermatitis in the natural mummy of the Roman Catholic nun Marie-Léonie Martin (France, 1863–1941)","authors":"Ruggero D’Anastasio, Francesca Monza, Jacopo Cilli, Luigi Capasso","doi":"10.1016/j.ijpp.2022.09.001","DOIUrl":"10.1016/j.ijpp.2022.09.001","url":null,"abstract":"<div><h3>Objective</h3><p>To document skin lesions on a mummified individual from the XIX century and to diagnose the pathology based historical documentation and physical examination.</p></div><div><h3>Materials</h3><p>Marie Leonie Martin (1863–1941) was a Roman Catholic nun. Her naturally mummified body is currently preserved in the Monastery of the Visitation in Caen (France). On the occasion of her beatification, the body was exhumed, studied and restored for conservation purposes.</p></div><div><h3>Methods</h3><p>The mummy was analyzed histologically and with CT imaging.</p></div><div><h3>Results</h3><p>The examination of the body noted areas of skin discoloration of reddish color; the paleopathological investigations revealed the presence of skin lesions (pustules) distributed throughout the body, with the exception of the face, abdomen and palms. The histological analyses of the pustules showed the presence of a central duct for the leakage of exudate, hyperkeratosis of the stratum corneum and a proliferation of cells in the spinous layer (acanthosis) of the epidermis.</p></div><div><h3>Conclusions</h3><p>The red discoloration of the skin is typical of extensive erythema.</p></div><div><h3>Significance</h3><p>Our understanding of skin conditions in the past is extremely limited. This study provides the first paleopathological case of diagnosed unclassified endogenous eczema and provides insight into the antiquity and effects of the disease.</p></div><div><h3>Limitations</h3><p>It was not possible to carry out a genetic analysis due to DNA contamination of the mummy.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 64-69"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10397370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica Hider , Ana T. Duggan , Jennifer Klunk , Katherine Eaton , George S. Long , Emil Karpinski , Valentina Giuffra , Luca Ventura , Antonio Fornaciari , Gino Fornaciari , G. Brian Golding , Tracy L. Prowse , Hendrik N. Poinar
{"title":"Examining pathogen DNA recovery across the remains of a 14th century Italian friar (Blessed Sante) infected with Brucella melitensis","authors":"Jessica Hider , Ana T. Duggan , Jennifer Klunk , Katherine Eaton , George S. Long , Emil Karpinski , Valentina Giuffra , Luca Ventura , Antonio Fornaciari , Gino Fornaciari , G. Brian Golding , Tracy L. Prowse , Hendrik N. Poinar","doi":"10.1016/j.ijpp.2022.08.002","DOIUrl":"10.1016/j.ijpp.2022.08.002","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate variation in ancient DNA recovery of <em>Brucella melitensis,</em> the causative agent of brucellosis, from multiple tissues belonging to one individual</p></div><div><h3>Materials</h3><p>14 samples were analyzed from the mummified remains of the Blessed Sante, a 14 <sup>th</sup> century Franciscan friar from central Italy, with macroscopic diagnosis of probable brucellosis.</p></div><div><h3>Methods</h3><p>Shotgun sequencing data from was examined to determine the presence of <em>Brucella</em> DNA.</p></div><div><h3>Results</h3><p>Three of the 14 samples contained authentic ancient DNA, identified as belonging to <em>B. melitensis</em>. A genome (23.81X depth coverage, 0.98 breadth coverage) was recovered from a kidney stone. Nine of the samples contained reads classified as <em>B. melitensis</em> (7−169), but for many the data quality was insufficient to withstand our identification and authentication criteria.</p></div><div><h3>Conclusions</h3><p>We identified significant variation in the preservation and abundance of <em>B. melitensis</em> DNA present across multiple tissues, with calcified nodules yielding the highest number of authenticated reads. This shows how greatly sample selection can impact pathogen identification.</p></div><div><h3>Significance</h3><p>Our results demonstrate variation in the preservation and recovery of pathogen DNA across tissues. This study highlights the importance of sample selection in the reconstruction of infectious disease burden and highlights the importance of a holistic approach to identifying disease.</p></div><div><h3>Limitations</h3><p>Study focuses on pathogen recovery in a single individual.</p></div><div><h3>Suggestions for further research</h3><p>Further analysis of how sampling impacts aDNA recovery will improve pathogen aDNA recovery and advance our understanding of disease in past peoples</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 20-34"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10388402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A paleoepidemiological approach to the challenging differential diagnosis of an isolated 1500-year-old anomalous molar from Panamá","authors":"Nicole E. Smith-Guzmán","doi":"10.1016/j.ijpp.2022.07.002","DOIUrl":"10.1016/j.ijpp.2022.07.002","url":null,"abstract":"<div><h3>Objective</h3><p>This study seeks to quantify the presence and prevalence of specific genetic and infectious diseases in the pre-Colombian Panamanian population and uses these data to consider the plausibility of these diseases as causative factors in the development of an abnormal supernumerary cusp morphology in a 1500-year-old isolated molar recovered from Cerro Juan Díaz (Los Santos, Panama).</p></div><div><h3>Materials</h3><p>267 individuals from pre-Columbian sites throughout Panama.</p></div><div><h3>Methods</h3><p>The anomalous tooth was analyzed through macroscopic, odontometric, and radiographic means. Tentative differential diagnosis was performed using inferences from paleopathological features of the broader regional population.</p></div><div><h3>Results</h3><p>The regional sample showed evidence of treponemal infection and developmental anomalies in 10.1% and 10.9% of individuals, respectively.</p></div><div><h3>Conclusions</h3><p>While not able to rule out three potential genetic conditions, more evidence was found to support the differential diagnosis of congenital syphilis as the causative agent leading to the development of abnormal supernumerary cusps in the isolated molar.</p></div><div><h3>Significance</h3><p>This study demonstrates how characterizing disease experience in the population can assist in differential diagnoses at the individual level and cautions against the assumption that any one lesion in isolation is unique to only one specific pathological condition.</p></div><div><h3>Limitations</h3><p>The timing discrepancy between clinical descriptions of congenital syphilis and genetic disorders, lack of knowledge on pathophysiological mechanisms of the former, poor preservation of <em>Treponema</em> pathogen ancient DNA, and deficiencies in modern public health data from Panama limit the differential diagnosis.</p></div><div><h3>Suggestions for further research</h3><p>Inclusion and serious contemplation of genetic diseases in paleopathological differential diagnoses is necessary.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 1-13"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1879981722000389/pdfft?md5=00e1a196f2dd77294c50ebf139d2b5c7&pid=1-s2.0-S1879981722000389-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10387860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The dark satanic mills: Evaluating patterns of health in England during the industrial revolution","authors":"Jo Buckberry , Gillian Crane-Kramer","doi":"10.1016/j.ijpp.2022.10.002","DOIUrl":"10.1016/j.ijpp.2022.10.002","url":null,"abstract":"<div><h3>Objective</h3><p>this research seeks to investigate the impact the industrial revolution had on the population of England.</p></div><div><h3>Materials</h3><p>Pre-existing skeletal data from 1154 pre-Industrial (1066–1700 CE) and 4157 industrial (1700–1905) skeletons from 21 cemeteries (N = 5411).</p></div><div><h3>Methods</h3><p>Context number, sex, age-at-death, stature and presence/absence of selected pathological conditions were collated. The data were compared using chi square, Kolmogorov-Smirnov, t-tests and logistic regression (α = 0.01).</p></div><div><h3>Results</h3><p>There was a statistically significant increase in cribra orbitalia, periosteal reactions, rib lesions, fractures, rickets, osteoporosis, osteoarthritis, enamel hypoplasia, dental caries and periapical lesions in the industrial period. Osteomyelitis decreased from the pre-industrial to industrial period.</p></div><div><h3>Conclusion</h3><p>Our results confirm the industrial revolution had a significant negative impact on human health, however the prevalence of TB, treponemal disease, maxillary sinusitis, osteomalacia, scurvy, gout and DISH did not change, suggesting these diseases were not impacted by the change in environmental conditions.</p></div><div><h3>Significance</h3><p>This is the largest study of health in the industrial revolution that includes non-adults and adults and considers age-at-death alongside disease status to date. This data supports the hypothesis that the rise of industry was associated with a significant decline in general health, but not an increase in all pathological conditions.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 93-108"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1879981722000523/pdfft?md5=6a501757284e491aa7413e6322ee419b&pid=1-s2.0-S1879981722000523-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10397918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Compounding vulnerabilities: Syndemics and the social determinants of disease in the past","authors":"Megan A. Perry , Rebecca L. Gowland","doi":"10.1016/j.ijpp.2022.09.002","DOIUrl":"10.1016/j.ijpp.2022.09.002","url":null,"abstract":"<div><h3>Objective</h3><p>This article explores the theory and utility of a syndemic approach for the study of disease in the past. Syndemic principles are examined alongside other theoretical developments within bioarchaeology. Two case studies are provided to illustrate the efficacy of this approach: Tuberculosis and vitamin D deficiency in 18th and 19th century England, and malaria and helminth infections in Early Medieval England.</p></div><div><h3>Materials</h3><p>Public health studies of present syndemics, in addition to published bioarchaeological, clinical and social information relating to the chosen case studies.</p></div><div><h3>Methods</h3><p>The data from these two historical examples are revisited within a syndemic framework to draw deeper conclusions about disease clustering and heterogeneity in the past.</p></div><div><h3>Results</h3><p>A syndemic framework can be applied to past contexts using clinical studies of diseases in a modern context and relevant paleopathological, archaeological, and historical data.</p></div><div><h3>Conclusions</h3><p>This approach provides a means for providing a deeper, contextualised understanding ancient diseases, and integrates well with extant theoretical tools in bioarchaeology</p></div><div><h3>Significance</h3><p>Syndemics provides scholars a deep-time perspective on diseases that still impact modern populations.</p></div><div><h3>Limitations</h3><p>Many of the variables essential for a truly syndemic approach cannot be obtained from current archaeological, bioarchaeological, or historical methods.</p></div><div><h3>Suggestions for further research</h3><p>More detailed and in-depth analysis of specific disease clusters within the past and the present, which draws on a comprehensive analysis of the social determinants of health.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 35-49"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10401716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giuffra Valentina , Rubino Luigi , Buzic Ileana , Milanese Marco
{"title":"Osteoma of the zygomatic bone from 16th century Sardinia (Italy) in the framework of a paleoepidemiological study","authors":"Giuffra Valentina , Rubino Luigi , Buzic Ileana , Milanese Marco","doi":"10.1016/j.ijpp.2022.10.003","DOIUrl":"10.1016/j.ijpp.2022.10.003","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of this paper is to evaluate a case of osteoma of the zygomatic bone in a post-medieval individual in the context of a paleoepidemiological approach.</p></div><div><h3>Materials</h3><p>Forty-five skulls from the plague cemetery of Alghero (Sardinia, Italy), dating back to the end of the 16th century, were evaluated for the presence of osteomata on the outer surface of the cranial vault and facial bones.</p></div><div><h3>Methods</h3><p>Macroscopic examination was performed using standard anthropological methods. The bone presenting the lesion was submitted to radiological examination through cone beam; a 3D reconstruction was obtained with a surface 3D scanner.</p></div><div><h3>Results</h3><p>Only one case of osteoma was observed in an adolescent aged 13–15 years, located on the right zygomatic bone. The lesion consisted of a rounded mass of 0.5 cm in diameter composed of compact bone, as also the radiographic study demonstrates. The prevalence of osteoma on the outer surface of the cranial vault and facial bones in the population of Alghero was 2.2 %.</p></div><div><h3>Conclusions</h3><p>This case offers the opportunity to enrich the knowledge about the presence of benign tumors among past populations and to evaluate this lesion in dry bone.</p></div><div><h3>Significance</h3><p>This study provides paleoepidemiological data on the scarce area of benign tumors in paleo-oncology and presents the first documented osteoma of the zygomatic bone in paleopathology.</p></div><div><h3>Limitation</h3><p>Histological study was not performed for conservative issues.</p></div><div><h3>Suggestions for future research</h3><p>Increasing the attention to benign tumors is essential to deepen our knowledge about paleoepidemiology of neoplastic lesions.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 70-74"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10457038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The madness they endured: A biocultural examination of women's experiences of structural violence within 20th-century Missouri state mental hospitals","authors":"Madeline M. Atwell","doi":"10.1016/j.ijpp.2022.05.001","DOIUrl":"10.1016/j.ijpp.2022.05.001","url":null,"abstract":"<div><h3>Objective</h3><p>This study employs feminist disability theory and the concept of structural violence to interpret the results of skeletal and documentary analysis of fracture and disease presence (i.e., syphilis and tuberculosis) among a group of institutionalized women who lived and died within 20th-century Missouri state mental hospitals.</p></div><div><h3>Materials</h3><p>The skeletal remains and corresponding death certificates of 52 adult Euro-American women housed in the Robert J. Terry Anatomical Collection at the Smithsonian Museum Support Center. Archival and historical literature concerning state mental hospitals were also utilized.</p></div><div><h3>Methods</h3><p>Macroscopic skeletal analysis of fracture and disease combined with archival research (i.e., associated death certificates and historical documentation).</p></div><div><h3>Results</h3><p>Approximately 15% of patients demonstrated evidence of perimortem hip fractures with no surgical intervention, most of whom were labeled \"psychotic\". Death certificates revealed the presence of syphilis (n = 4) and death from TB (n = 5).</p></div><div><h3>Conclusions</h3><p>Nineteenth and 20th-century patriarchal conditions contributed to the institutionalization of women. Women who were impoverished, spouseless, and perceived as mentally or physically disabled were particularly vulnerable to institutionalization. Once hospitalized, patients were exposed to structurally violent conditions including neglect and abuse that resulted in avoidable harm.</p></div><div><h3>Significance</h3><p>Historical and documentary data associated with osteological collections is underutilized and can serve to both humanize these individuals and advance our understanding of their intersectional experiences. The implementation of theoretical frameworks within bioarchaeology can also assist in more holistically interpreting the complexities of past life.</p></div><div><h3>Limitations</h3><p>Small, homogenous sample size limited by macroscopic analysis.</p></div><div><h3>Further Research</h3><p>Future work should increase sample size, heterogeneity, and conduct other relevant skeletal and documentary analyses.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 75-84"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10398151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case of bilateral humerus varus from the late antiquity Catacomb of Santa Mustiola (Chiusi, Italy)","authors":"Alessandra Sperduti , Matteo Braconi , Claudio Di Biasi , Giulia Facchin , Giovanna Ferri , Stella Interlando , Ferdinando Spanò , Francesca Candilio","doi":"10.1016/j.ijpp.2022.08.001","DOIUrl":"10.1016/j.ijpp.2022.08.001","url":null,"abstract":"<div><h3>Objective</h3><p>To report a case of bilateral humerus varus from a late antiquity archeological context in central Italy.</p></div><div><h3>Materials</h3><p>The individual is a 25–40-year-old female, dated to the 4th cent. CE, from the catacomb of Santa Mustiola in Chiusi, Italy.</p></div><div><h3>Methods</h3><p>The bones were examined macroscopically and through CT scan imaging.</p></div><div><h3>Results</h3><p>Both humeri show evident alterations in shape, including elongated, flattened and distally dislocated humeral heads, shortened anatomical necks, angulated upper diaphyseal shafts, and reduced overall lengths. The scapulae appear to have been mildly affected by this condition and show some bone loss and slight retroversion of the glenoid cavity.</p></div><div><h3>Conclusions</h3><p>Observations are consistent with a diagnosis of humerus varus deformity likely caused by a traumatic event early in the individual's life.</p></div><div><h3>Significance</h3><p>Varus deformity of the proximal humerus is seldom reported in bioarcheological literature. The case presented provides insight into the etiology and effects of this condition and may serve as comparison for future studies.</p></div><div><h3>Limitations</h3><p>Even though the absence of other skeletal deformities renders a systemic condition improbable, the traumatic etiology of the condition cannot be confirmed with certainty.</p></div><div><h3>Suggestions for further research</h3><p>Future publications of new cases may give a broader perspective of the etiology of this condition in the past.</p></div>","PeriodicalId":48817,"journal":{"name":"International Journal of Paleopathology","volume":"39 ","pages":"Pages 14-19"},"PeriodicalIF":1.2,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10387865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"地球科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}