Ana Ribeiro , Pierre-Hadrien Decaup , Marion Andriantavy , Christine Couture , Elsa Garot
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Our review, based on 25 diseases, lists the bone and dental lesions observable in archeological remains.</p></div><div><h3>Conclusions</h3><p>Based on a review of the literature, a synthesis of 25 diseases and syndromes that may be associated with premature loss of permanent or deciduous teeth in children was developed for paleopathologists. 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引用次数: 0
摘要
目的为古病理学家提供以证据为基础的资源，以考虑与儿童早期缺牙相关的多种骨骼病理指标，从而帮助诊断。方法根据系统综述指南 PRISMA（系统综述和 Meta 分析首选报告项目）标准，选择了 85 篇文章。我们的综述以 25 种疾病为基础，列出了在考古遗存中可观察到的骨骼和牙齿病变。结论根据文献综述，我们为古病理学家总结了 25 种可能与儿童恒牙或乳牙过早脱落有关的疾病和综合征。本文提供了有关儿童早期牙齿缺失的大量资料，可帮助研究人员进行鉴别诊断。对进一步研究的建议对疾病及其与早期牙齿缺失的关系进行进一步研究将是对这项工作的补充，对考古个体进行鉴别诊断也将有助于明确其价值和局限性。
Skeletal indicators of pathology in the context of early tooth loss in children: A systematic literature review
Objective
To provide an evidence-based resource for paleopathologists to consider multiple skeletal indicators of pathology associated with early tooth loss in children to aid in diagnosis.
Materials
Three databases (Cochrane Library, MedLine, and Scopus) were used for a review.
Methods
According to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) criteria, a systematic review guideline, 85 articles were selected.
Results
A total of 189 children had a syndrome or disease associated with early tooth loss. Our review, based on 25 diseases, lists the bone and dental lesions observable in archeological remains.
Conclusions
Based on a review of the literature, a synthesis of 25 diseases and syndromes that may be associated with premature loss of permanent or deciduous teeth in children was developed for paleopathologists. It highlights the importance of a thorough dental examination by paleopathologists to further assess past health conditions.
Significance
This paper provides an extensive resource addressing early tooth loss in childhood to assist researchers with differential diagnosis.
Limitations
The articles included in this review are case reports based on living populations.
Suggestions for further research
Further studies into diseases and their association with early tooth loss would complement this work, as would utilizing the differential diagnoses on archeological individuals to clarify its value and limitations.
期刊介绍：
Paleopathology is the study and application of methods and techniques for investigating diseases and related conditions from skeletal and soft tissue remains. The International Journal of Paleopathology (IJPP) will publish original and significant articles on human and animal (including hominids) disease, based upon the study of physical remains, including osseous, dental, and preserved soft tissues at a range of methodological levels, from direct observation to molecular, chemical, histological and radiographic analysis. Discussion of ways in which these methods can be applied to the reconstruction of health, disease and life histories in the past is central to the discipline, so the journal would also encourage papers covering interpretive and theoretical issues, and those that place the study of disease at the centre of a bioarchaeological or biocultural approach. Papers dealing with historical evidence relating to disease in the past (rather than history of medicine) will also be published. The journal will also accept significant studies that applied previously developed techniques to new materials, setting the research in the context of current debates on past human and animal health.
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