Marcus Winogradzki , Shreya Patel , Waddell Holmes , Ahmad H. Othman , Alan Blank , Ryan Ross , Jitesh Pratap
{"title":"#29. A novel control mechanism of endosomal trafficking in bone metastatic breast cancer cells","authors":"Marcus Winogradzki , Shreya Patel , Waddell Holmes , Ahmad H. Othman , Alan Blank , Ryan Ross , Jitesh Pratap","doi":"10.1016/j.jbo.2024.100567","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100567","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000472/pdfft?md5=b8494741960904b507ddb5422307745b&pid=1-s2.0-S2212137424000472-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xinming Su , Takayuki Kobayashi , Jingyu Xiang , Yalin Xu , Ayesha N. Shajahan-Haq , Mahta Mardani , Suleyman Noordeen , Kaylee O'Donnell , Kristin A. Kwakwa , Francesca Fontana , Deborah J. Veis , Gregory M. Lanza , Katherine N. Weilbaecher
{"title":"CDK4/6 inhibitor and doxorubicin synergistically inhibit breast cancer bone metastasis and enhance T-cell targeted therapy","authors":"Xinming Su , Takayuki Kobayashi , Jingyu Xiang , Yalin Xu , Ayesha N. Shajahan-Haq , Mahta Mardani , Suleyman Noordeen , Kaylee O'Donnell , Kristin A. Kwakwa , Francesca Fontana , Deborah J. Veis , Gregory M. Lanza , Katherine N. Weilbaecher","doi":"10.1016/j.jbo.2024.100538","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100538","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000186/pdfft?md5=0e3acfb07f3f0b836b762c171cb7d753&pid=1-s2.0-S2212137424000186-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140640718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marie-Therese Haider , Jennifer Zarrer , Nicole Ridlmaier , Rafael Preuer , Daniel J. Smit , Hiroaki Saito , Eric Hesse , Hanna Taipaleenmäki
{"title":"#3. IL-17A supports osteoblasts to become cancer-associated fibroblasts in breast cancer bone metastases","authors":"Marie-Therese Haider , Jennifer Zarrer , Nicole Ridlmaier , Rafael Preuer , Daniel J. Smit , Hiroaki Saito , Eric Hesse , Hanna Taipaleenmäki","doi":"10.1016/j.jbo.2024.100541","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100541","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000216/pdfft?md5=cb82ad87c1a39607f970311696ab9148&pid=1-s2.0-S2212137424000216-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140640857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Toshinao Oyama , Richa Rathore , Caitlyn B. Brashears , Katharine E. Caldwell , Brian A. Van Tine
{"title":"#36. Novel therapeutic development with serine biosynthesis inhibition and molecularly targeted drugs against the aggressive osteosarcoma","authors":"Toshinao Oyama , Richa Rathore , Caitlyn B. Brashears , Katharine E. Caldwell , Brian A. Van Tine","doi":"10.1016/j.jbo.2024.100574","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100574","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221213742400054X/pdfft?md5=757d2fe0671f32eedb38d8b7b63f0963&pid=1-s2.0-S221213742400054X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140640911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Pokhrel , A Panfil , H Habib , S Seeniraj , D Rauch , A Joseph , R Aurora , Y Lianbo , AS Yilmaz , R Sprung , P Gilmore , Z Qiang , R Townsend , K Weilbaecher , D Veis
{"title":"#19. RANKL independent osteolysis in Adult T cell leukemia via small extracellular vesicles","authors":"N Pokhrel , A Panfil , H Habib , S Seeniraj , D Rauch , A Joseph , R Aurora , Y Lianbo , AS Yilmaz , R Sprung , P Gilmore , Z Qiang , R Townsend , K Weilbaecher , D Veis","doi":"10.1016/j.jbo.2024.100557","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100557","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221213742400037X/pdfft?md5=c08815893c42390bc34400365eaf8e56&pid=1-s2.0-S221213742400037X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan T. Bishop , Tao Li , Raghunandan R. Alugubelli , Mostafa Nasr , Karl J. Nyman , Praneeth Sudalagunta , Mark Meads , Jeremy Frieling , Niveditha Nerlakanti , Marilena Tauro , Oliver Hampton , Bin Fang , Steven Grant , John Koomen , Ariosto Siqueira Silva , Kenneth H. Shain , Conor C. Lynch
{"title":"#1. Acid ceramidase (ASAH1) is a key mediator of drug resistance in relapsed/refractory multiple myeloma","authors":"Ryan T. Bishop , Tao Li , Raghunandan R. Alugubelli , Mostafa Nasr , Karl J. Nyman , Praneeth Sudalagunta , Mark Meads , Jeremy Frieling , Niveditha Nerlakanti , Marilena Tauro , Oliver Hampton , Bin Fang , Steven Grant , John Koomen , Ariosto Siqueira Silva , Kenneth H. Shain , Conor C. Lynch","doi":"10.1016/j.jbo.2024.100539","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100539","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000198/pdfft?md5=a645f6343ae4a9b7a3e874228c870696&pid=1-s2.0-S2212137424000198-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Renata Ramalho-Oliveira, Douglas V. Faget, Xianmin Luo, Jiayu Ye, Sheila A. Stewart
{"title":"#53. Limiting metastatic breast cancer progression by targeting MK2 stromal signaling","authors":"Renata Ramalho-Oliveira, Douglas V. Faget, Xianmin Luo, Jiayu Ye, Sheila A. Stewart","doi":"10.1016/j.jbo.2024.100591","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100591","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221213742400071X/pdfft?md5=9730fd3ad2c17268b97523b48c9b1698&pid=1-s2.0-S221213742400071X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuzhong Liu , Xi Zhou , Yong Liu , Jianguo Zhang , Weibo Xia
{"title":"Preoperative evaluation and orthopedic surgical strategies for tumor-induced osteomalacia","authors":"Shuzhong Liu , Xi Zhou , Yong Liu , Jianguo Zhang , Weibo Xia","doi":"10.1016/j.jbo.2024.100600","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100600","url":null,"abstract":"<div><p>Tumor-induced osteomalacia (TIO), also known as oncogenic osteomalacia, is very rare, with about 1000 reported cases globally. Removing most TIO culprit tumors requires the evaluation and intervention of orthopedic doctors. However, orthopedic doctors often have a poor understanding of the optical treatment of TIO due to its rarity. In addition, most TIO patients lack specific clinical manifestations. Also, the clinical localization and qualitative diagnosis of TIO are difficult and thus can easily be misdiagnosed and mistreated. Furthermore, the true incidence rate of TIO may be underestimated. Although many breakthroughs have been made in exploring the pathogenesis, clinical diagnosis, and treatment of TIO, rational and standardized orthopedic surgical treatment experience summary and sorting for TIO patients are lacking. In this article, the recent experience and progress in the field of orthopedic surgical treatment for TIO globally have been summarized, providing a theoretical basis and new clinical practice guidance for the rational treatment of TIO patients.</p></div>","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000800/pdfft?md5=33b6d95aeef87894de1a0b6f75140758&pid=1-s2.0-S2212137424000800-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140330734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristin A. Kwakwa , Gregory C. Fox , Michael H. Ross , Xinming Su , Yalin Xu , Netra Navadkar , Gregory M. Lanza , Christopher A. Maher , Katherine N. Weilbaecher
{"title":"#22. Investigating the TGF-β/integrin β3 signaling axis as a mediator of chemoresistance in breast cancer bone metastasis","authors":"Kristin A. Kwakwa , Gregory C. Fox , Michael H. Ross , Xinming Su , Yalin Xu , Netra Navadkar , Gregory M. Lanza , Christopher A. Maher , Katherine N. Weilbaecher","doi":"10.1016/j.jbo.2024.100560","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100560","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S221213742400040X/pdfft?md5=1d95e72cdd4236b30e4dc69415b35812&pid=1-s2.0-S221213742400040X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140640830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brittany Johnson , Federico Nebuloni , Srinivasa R. Rao , Edmond J. Walsh , Claire M. Edwards
{"title":"#20. Investigating the response of prostate cancer cells to bone-derived growth factor gradients via fluid-wall microfluidic culture systems","authors":"Brittany Johnson , Federico Nebuloni , Srinivasa R. Rao , Edmond J. Walsh , Claire M. Edwards","doi":"10.1016/j.jbo.2024.100558","DOIUrl":"https://doi.org/10.1016/j.jbo.2024.100558","url":null,"abstract":"","PeriodicalId":48806,"journal":{"name":"Journal of Bone Oncology","volume":null,"pages":null},"PeriodicalIF":3.4,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2212137424000381/pdfft?md5=955ffdb08ddb45e735bf7e886e01b406&pid=1-s2.0-S2212137424000381-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140641188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}