基于补丁的深度学习磁共振成像分割模型,用于提高脊柱肿瘤的检查效率和临床检查效果

IF 3.4 2区 医学 Q2 Medicine
Weimin Chen , Yong Han , Muhammad Awais Ashraf , Junhan Liu , Mu Zhang , Feng Su , Zhiguo Huang , Kelvin K.L. Wong
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引用次数: 0

摘要

背景和目的磁共振成像(MRI)在诊断脊柱疾病(包括不同类型的脊柱肿瘤)方面发挥着重要作用。然而,传统的分割技术往往耗费大量人力物力,而且容易产生变异。本研究旨在利用卷积-去卷积神经网络和基于补丁的深度学习,提出一种全自动脊柱磁共振成像分割方法。该方法涉及利用卷积神经网络从脊柱数据中自动提取深度学习特征。这样就能有效地表示解剖结构。对网络进行训练,以学习准确分割脊柱磁共振成像数据所需的鉴别特征。此外,还利用卷积神经网络开发了基于斑块提取(PE)的深度神经网络,将特征图还原为原始图像大小。为了提高训练效率,我们结合使用了预训练和增强型随机梯度下降方法。 实验结果实验结果表明,所提出的方法在使用钆增强 T1 MRI 进行脊柱图像分割方面非常有效。这种方法不仅准确度高,而且具有实时性。创新模型获得了令人印象深刻的指标,精确度达到 90.6%,召回率达到 91.1%,准确率达到 93.2%,F1 分数达到 91.3%,联合交叉(IoU)达到 83.8%,骰子系数(DC)达到 91.1%。这些结果表明,所提出的方法可以准确分割脊柱肿瘤 CT 图像,解决了传统分割算法的局限性。结论总之,本研究介绍了一种利用卷积神经网络对脊柱 MRI 图像进行全自动分割的方法,并通过应用 PE 模块进行了增强。通过利用基于补丁提取的神经网络(PENN)深度学习技术,所提出的方法有效地解决了传统算法的不足,实现了准确、实时的脊柱 MRI 图像分割。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A patch-based deep learning MRI segmentation model for improving efficiency and clinical examination of the spinal tumor

Background and objective

Magnetic resonance imaging (MRI) plays a vital role in diagnosing spinal diseases, including different types of spinal tumors. However, conventional segmentation techniques are often labor-intensive and susceptible to variability. This study aims to propose a full-automatic segmentation method for spine MRI images, utilizing a convolutional-deconvolution neural network and patch-based deep learning. The objective is to improve segmentation efficiency, meeting clinical needs for accurate diagnoses and treatment planning.

Methods

The methodology involved the utilization of a convolutional neural network to automatically extract deep learning features from spine data. This allowed for the effective representation of anatomical structures. The network was trained to learn discriminative features necessary for accurate segmentation of the spine MRI data. Furthermore, a patch extraction (PE) based deep neural network was developed using a convolutional neural network to restore the feature maps to their original image size. To improve training efficiency, a combination of pre-training and an enhanced stochastic gradient descent method was utilized.

Results

The experimental results highlight the effectiveness of the proposed method for spine image segmentation using Gadolinium-enhanced T1 MRI. This approach not only delivers high accuracy but also offers real-time performance. The innovative model attained impressive metrics, achieving 90.6% precision, 91.1% recall, 93.2% accuracy, 91.3% F1-score, 83.8% Intersection over Union (IoU), and 91.1% Dice Coefficient (DC). These results indicate that the proposed method can accurately segment spine tumors CT images, addressing the limitations of traditional segmentation algorithms.

Conclusion

In conclusion, this study introduces a fully automated segmentation method for spine MRI images utilizing a convolutional neural network, enhanced by the application of the PE-module. By utilizing a patch extraction based neural network (PENN) deep learning techniques, the proposed method effectively addresses the deficiencies of traditional algorithms and achieves accurate and real-time spine MRI image segmentation.
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来源期刊
CiteScore
7.20
自引率
2.90%
发文量
50
审稿时长
34 days
期刊介绍: The Journal of Bone Oncology is a peer-reviewed international journal aimed at presenting basic, translational and clinical high-quality research related to bone and cancer. As the first journal dedicated to cancer induced bone diseases, JBO welcomes original research articles, review articles, editorials and opinion pieces. Case reports will only be considered in exceptional circumstances and only when accompanied by a comprehensive review of the subject. The areas covered by the journal include: Bone metastases (pathophysiology, epidemiology, diagnostics, clinical features, prevention, treatment) Preclinical models of metastasis Bone microenvironment in cancer (stem cell, bone cell and cancer interactions) Bone targeted therapy (pharmacology, therapeutic targets, drug development, clinical trials, side-effects, outcome research, health economics) Cancer treatment induced bone loss (epidemiology, pathophysiology, prevention and management) Bone imaging (clinical and animal, skeletal interventional radiology) Bone biomarkers (clinical and translational applications) Radiotherapy and radio-isotopes Skeletal complications Bone pain (mechanisms and management) Orthopaedic cancer surgery Primary bone tumours Clinical guidelines Multidisciplinary care Keywords: bisphosphonate, bone, breast cancer, cancer, CTIBL, denosumab, metastasis, myeloma, osteoblast, osteoclast, osteooncology, osteo-oncology, prostate cancer, skeleton, tumour.
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