Journal of Periodontal and Implant Science最新文献

{"title":"Risk indicators associated with peri-implant diseases: a retrospective cross-sectional study of Colombian patients with 1 to 18 years of follow-up.","authors":"Ana María Ortiz-Echeverri, Carolina Gallego-González, María Catalina Castaño-Granada, Sergio Iván Tobón-Arroyave","doi":"10.5051/jpis.2300140007","DOIUrl":"10.5051/jpis.2300140007","url":null,"abstract":"<p><strong>Purpose: </strong>Peri-implant mucositis (PIM) and peri-implantitis (PI) are multicausal conditions with several risk factors contributing to their pathogenesis. In this study, we retrospectively investigated risk variables potentially associated with these peri-implant diseases (PIDs) over a follow-up period of 1 to 18 years.</p><p><strong>Methods: </strong>The study sample consisted of 379 implants placed in 155 patients. Single-visit clinical and radiographic evaluations were employed to determine the presence or absence of PIDs. Parameters related to the patient, site, surgery, implant, and prosthetic restoration were documented. The relationships between risk variables and the occurrence of PIDs were individually examined and adjusted for confounders using multivariate binary logistic regression models.</p><p><strong>Results: </strong>The prevalence rates of PIM and PI were 28.4% and 36.8% at the patient level and 33.5% and 24.5% at the implant level, respectively. Poor oral hygiene, active gingivitis/periodontitis, preoperative alveolar ridge deficiency, early or delayed implant placement, implant length of 11.0 mm or less, and poor restoration quality were strong and independent risk indicators for both PIDs. Furthermore, a follow-up period of more than 5 years and a loading time of more than 4 years were important indicators for PI. Simultaneously, age and smoking status acted as modifiers of the effect of mesiodistal (MD) and buccolingual (BL) widths of restoration on PI.</p><p><strong>Conclusions: </strong>In this study population, oral hygiene, periodontal status, preoperative alveolar ridge status, implant placement protocol, implant length, and the quality of coronal restoration appear to be robust risk indicators for both PIM and PI. Additionally, the length of follow-up and functional loading time are robust indicators of PI. Furthermore, the potential modifying relationships of age and smoking status with the MD and BL widths of restoration may be crucial for the development of PI.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":" ","pages":"161-176"},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10535718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel approach to assessing the primary stability of dental implants under functional cyclic loading <i>in vitro</i>: a biomechanical pilot study using synthetic bone.","authors":"Jean-Pierre Fischer, Stefan Schleifenbaum, Felicitas Gelberg, Thomas Barth, Toni Wendler, Sabine Löffler","doi":"10.5051/jpis.2301780089","DOIUrl":"10.5051/jpis.2301780089","url":null,"abstract":"<p><strong>Purpose: </strong>This pilot study was conducted to develop a novel test setup for the <i>in vitro</i> assessment of the primary stability of dental implants. This was achieved by characterising their long-term behaviour based on the continuous recording of micromotions resulting from dynamic and cyclic loading.</p><p><strong>Methods: </strong>Twenty screw implants, each 11 mm in length and either 3.8 mm (for premolars) or 4.3 mm (for molars) in diameter, were inserted into the posterior region of 5 synthetic mandibular models. Physiological masticatory loads were simulated by superimposing cyclic buccal-lingual movement of the mandible with a vertically applied masticatory force. Using an optical 3-dimensional (3D) measuring system, the micromotions of the dental crowns relative to the alveolar bone resulting from alternating off-centre loads were concurrently determined over 10,000 test cycles.</p><p><strong>Results: </strong>The buccal-lingual deflections of the dental crowns significantly increased from cycle 10 to cycle 10,000 (<i>P</i><0.05). The deflections increased sharply during the first 500 cycles before approaching a plateau. Premolars exhibited greater maximum deflections than molars. The bone regions located mesially and distally adjacent to the loaded implants demonstrated deflections that occurred synchronously and in the same direction as the applied loads. The overall spatial movement of the implants over time followed an hourglass-shaped loosening pattern with a characteristic pivot point 5.5±1.1 mm from the apical end.</p><p><strong>Conclusions: </strong>In synthetic mandibular models, the cyclic reciprocal loading of dental implants with an average masticatory force produces significant loosening. The evasive movements observed in the alveolar bone suggest that its anatomy and yielding could significantly influence the force distribution and, consequently, the mechanical behaviour of dental implants. The 3D visualisation of the overall implant movement under functional cyclic loading complements known methods and can contribute to the development of implant designs and surgical techniques by providing a more profound understanding of dynamic bone-implant interactions.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":" ","pages":"189-204"},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the clinical effects of local administration of minocycline ointment and doxycycline solution in the treatment of acute periodontal abscesses: a retrospective clinical study.","authors":"DongYeol Jung, Jae-Kook Cha, Young-Taek Kim, Chang-Sung Kim","doi":"10.5051/jpis.2300800040","DOIUrl":"10.5051/jpis.2300800040","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this retrospective clinical study was to provide evidence supporting the adjunctive local application of doxycycline solution or minocycline ointment, in conjunction with drainage, for the treatment of acute periodontal abscesses.</p><p><strong>Methods: </strong>The study included 63 patients who had received treatment for acute periodontal abscesses through drainage supplemented with 1 of 3 types of adjunctive medications during their initial visit (visit 1; baseline): 1) saline irrigation (the control group), 2) 2% minocycline ointment (the TM group), or 3) 300 mg/mL doxycycline irrigation (the TD group). The same adjunctive medication was administered at visit 2, which took place 1 week after visit 1. Probing depth (PD), bleeding on probing (BOP), plaque index, gingival recession, clinical attachment level, and tooth mobility were clinically evaluated at visits 1, 2, and a third visit (visit 3; 4 weeks after visit 1). Statistical significance was considered to be indicated by <i>P</i> values <0.05.</p><p><strong>Results: </strong>By visit 3, all clinical indices and tooth mobility had significantly decreased in each group. At this visit, PD and BOP on the abscess side were significantly lower in the TM and TD groups compared to the control group. The TD group showed a significantly greater improvement than the TM group, with mean PD reductions of 1.09 mm in the control group, 1.88 mm in the TM group, and 2.88 mm in the TD group. Similarly, mean BOP reductions were 45% in the control group, 73.02% in the TM group, and 95.45% in the TD group.</p><p><strong>Conclusions: </strong>Local and adjunctive administration of doxycycline and minocycline in combination with drainage exhibited clinical advantages over drainage alone in improving PD and BOP. Notably, a doxycycline solution of 300 mg/mL was more effective than a 2% minocycline ointment.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":" ","pages":"149-160"},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49683925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum: Text Correction. Evaluation of the clinical and radiographic effectiveness of treating peri-implant bone defects with a new biphasic calcium phosphate bone graft: a prospective, multicenter randomized controlled trial.","authors":"Jae-Hong Lee, Hyun-Wook An, Jae-Seung Im, Woo-Joo Kim, Dong-Won Lee, Jeong-Ho Yun","doi":"10.5051/jpis.2423032err01","DOIUrl":"10.5051/jpis.2423032err01","url":null,"abstract":"<p><p>This corrects the article on p. 306 in vol. 53, PMID: 37524378.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"54 3","pages":"205"},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Attendance at conferences for researchers and editorial boards: the post-COVID landscape.","authors":"Jun-Beom Park, Shin-Young Park, Jung-Chul Park, Yong-Gun Kim, Hwan Tae Ahn, Seung-Yun Shin","doi":"10.5051/jpis.245403edi01","DOIUrl":"10.5051/jpis.245403edi01","url":null,"abstract":"","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"54 3","pages":"137-138"},"PeriodicalIF":2.2,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11227930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early wound healing at 1 week postoperatively in periodontal tissue regeneration therapy: enamel matrix derivative versus recombinant human fibroblast growth factor.","authors":"Yohei Nakayama, Moe Ogihara-Takeda, Yumi Saito, Arisa Yamaguchi, Yorimasa Ogata","doi":"10.5051/jpis.2400740037","DOIUrl":"https://doi.org/10.5051/jpis.2400740037","url":null,"abstract":"<p><strong>Purpose: </strong>Recombinant human fibroblast growth factor-2 (rhFGF-2) has demonstrated positive effects on wound healing at 2 weeks after periodontal surgery relative to enamel matrix derivative (EMD). However, the effects at earlier postoperative stages have not been reported. This retrospective study compared the early wound healing outcomes 1 week after surgery using the modified papilla preservation technique (mPPT) with either EMD or rhFGF-2 therapy.</p><p><strong>Methods: </strong>We compiled a list of all mPPT sites treated with EMD or rhFGF-2 during the survey period (September 2011 to March 2022). Early wound healing was assessed using the early wound healing score (EHS) and the modified early wound healing index (mEHI). Inter-rater reliability for the EHS and mEHI was established using intraclass correlation coefficients. Factors influencing mPPT were identified by analyzing the correlation coefficients between the EHS items, mEHI items, and potential influencing factors. After adjusting for factors impacting EHS, mEHI, and mPPT, we compared the EHS and mEHI between EMD and rhFGF-2 groups.</p><p><strong>Results: </strong>In total, 72 sites were evaluated. The scores for incision line, step, and dehiscence were significantly higher in those receiving rhFGF-2 (n=42) compared to those treated with EMD (n=30). The EHS item scores did not differ significantly between groups. Among patients aged ≥50 years, but not those <50 years, significantly higher step and dehiscence scores were found in the rhFGF-2 group than the EMD group (<i>P</i><0.01). Additionally, for patients exhibiting a clinical attachment level (CAL) ≥8 mm, the step score was significantly higher in the rhFGF-2 group than in the EMD group (<i>P</i><0.05), but this trend was not reflected in those with a CAL <8 mm.</p><p><strong>Conclusions: </strong>In this study, early wound closure at mPPT sites was more effectively achieved with rhFGF-2 than with EMD. Nevertheless, biochemical assessments are required to compare the re-epithelialization effects of these therapies.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteogenic potential of Frondoside A in human periodontal ligament cells: an RNA-Seq analysis.","authors":"Young Kim, Si-Won Kang, Ju Ri Ye, Seong Eun Kim, Yong Kwon Chae, Ok Hyung Nam","doi":"10.5051/jpis.2303840192","DOIUrl":"https://doi.org/10.5051/jpis.2303840192","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate the effects of Frondoside A (FA) on the osteogenic differentiation of human periodontal ligament (PDL) cells.</p><p><strong>Methods: </strong>Human PDL cells were cultured in osteogenic medium and treated with FA at concentrations of 0, 0.05, and 0.2 µM for 14 days. The expression levels of genes associated with osteogenic differentiation were assessed using quantitative real-time polymerase chain reaction analysis. Subsequently, RNA sequencing was performed to identify enriched gene sets following FA treatment. Alkaline phosphatase (ALP) activity was measured to confirm the osteogenic potential of FA.</p><p><strong>Results: </strong>Treatment with 0.2 µM FA significantly increased the expression levels of runt-related transcription factor 2 (<i>RUNX2</i>), <i>ALP</i>, and osteocalcin (<i>OCN</i>) at day 3, while also significantly elevating the expression of dentin sialophosphoprotein (<i>DSPP</i>), <i>RUNX2</i>, <i>ALP</i>, <i>OCN</i>, and osterix (<i>OSX</i>) at day 14 (<i>P</i><0.017). Hallmark gene sets enriched during FA treatment were associated with the KRAS (normalized enrichment score [NES]=2.02, <i>Q</i>=0.000), interferon alpha (IFN-α) (NES=1.88, <i>Q</i>=0.001), IFN-γ (NES=1.85, <i>Q</i><0.001), hypoxia (NES=1.79, <i>Q</i>=0.001), and p53 (NES=1.77, <i>Q</i>=0.001) signaling pathways. Additionally, treatment with 0.2 µM FA significantly intensified ALP staining at day 14 (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>Within the limitations of this study, FA treatment influenced periodontal regeneration by promoting the osteogenic differentiation of human PDL cells.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between the size of released titanium particles and changes in the surface of dental implants during insertion into bone blocks: an <i>in vitro</i> study.","authors":"Waad Kheder, Ab Rani Samsudin, Soumya Sheela, Sausan Al Kawas","doi":"10.5051/jpis.2204380219","DOIUrl":"https://doi.org/10.5051/jpis.2204380219","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated the size and amount of titanium particles immediately released following dental implant insertion into bovine bone blocks and aimed to correlate them with the surface roughness of the implants.</p><p><strong>Methods: </strong>Twelve bone blocks were prepared from bovine mandibles. Six tapered (group A) and 6 cylindrical (group B) dental implants were inserted into the bone blocks under water irrigation, following the standard drilling protocol. After insertion, the implants were immediately removed from the bone. Scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDX), and atomic force microscopy were performed to investigate the released titanium particles and implant surface roughness, respectively. The amount of titanium ions in the irrigation water was measured using inductively coupled plasma mass spectrometry. Dynamic light scattering (DLS) was used to determine the size range of the released titanium particles.</p><p><strong>Results: </strong>The percentages of titanium content on the surface of implants decreased in both groups after implantation into bone blocks. SEM-EDX analysis confirmed the presence of titanium particles embedded in the implanted bone bed. Group B implants showed significantly higher concentrations of titanium ions in the collected water than group A implants (0.868 and 0.565 µg/L, respectively). Group A implants demonstrated high pre-implantation surface roughness, which led to a much greater decrease in post-implantation surface roughness than was observed for group B implants. DLS analysis showed that the titanium particles released from group A implants were within the nano-size range, whereas those released from group B implants were within the micro-size range.</p><p><strong>Conclusions: </strong>Dental implant placement leads to a decrease in implant surface roughness and the immediate release of titanium particles into the peri-implant bone. Variations in the size range and amount of released particles were correlated with implant surface roughness. This finding has clinical implications and warrants additional <i>in vivo</i> studies.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revolutionizing scholarly publishing by integrating artificial intelligence into editorial and peer review processes.","authors":"Jun-Beom Park, Shin-Young Park, Jung-Chul Park, Yong-Gun Kim, Hwan Tae Ahn, Seung-Yun Shin","doi":"10.5051/jpis.245402edi01","DOIUrl":"https://doi.org/10.5051/jpis.245402edi01","url":null,"abstract":"","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":"54 2","pages":"63-64"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11065533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140855673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulp and periapical disease as a risk factor for osteonecrosis of the jaw: a national cohort-based study in Korea.","authors":"Hyeong-Jin Baek, Hyejin Lee, Jae-Ryun Lee, Jung-Hyun Park, Keun-Suh Kim, Min-Jeong Kwoen, Tae-Yeon Lee, Jin-Woo Kim, Hyo-Jung Lee","doi":"10.5051/jpis.2300120006","DOIUrl":"10.5051/jpis.2300120006","url":null,"abstract":"<p><strong>Purpose: </strong>This longitudinal cohort study aimed to evaluate the relationship between osteonecrosis of the jaw and pulp and periapical disease in patients who were administered bisphosphonates.</p><p><strong>Methods: </strong>Using data from a nationwide cohort, we examined the association among dental caries, pulp and periapical disease, and osteonecrosis of the jaw in women aged >50 years who received bisphosphonates for more than 1 year between 2002 and 2015. Because of ambiguities in the diagnosis of osteonecrosis of the jaw in population-based data, we operationally defined and categorized the condition into established and potential osteonecrosis of the jaw.</p><p><strong>Results: </strong>Pulp and periapical disease significantly increased the development of both established and potential osteonecrosis of the jaw (hazard ratio, 2.21; 95% confidence interval, 1.40-3.48; and hazard ratio, 2.22; 95% confidence interval, 1.65-2.98, respectively). Root canal treatment did not have any influence on the development of osteonecrosis of the jaw.</p><p><strong>Conclusions: </strong>Pulp and periapical disease may be a major risk factor for osteonecrosis of the jaw. The study findings suggest that patients should undergo regular dental examinations to detect pulp and periapical disease before or during the administration of bisphosphonates and that root canal treatment should be considered to decrease the risk of osteonecrosis of the jaw.</p>","PeriodicalId":48795,"journal":{"name":"Journal of Periodontal and Implant Science","volume":" ","pages":"65-74"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11065535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9911261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}