{"title":"Adversarial artificial intelligence in radiology: Attacks, defenses, and future considerations.","authors":"Nicholas Dietrich, Bo Gong, Michael N Patlas","doi":"10.1016/j.diii.2025.05.006","DOIUrl":"https://doi.org/10.1016/j.diii.2025.05.006","url":null,"abstract":"<p><p>Artificial intelligence (AI) is rapidly transforming radiology, with applications spanning disease detection, lesion segmentation, workflow optimization, and report generation. As these tools become more integrated into clinical practice, new concerns have emerged regarding their vulnerability to adversarial attacks. This review provides an in-depth overview of adversarial AI in radiology, a topic of growing relevance in both research and clinical domains. It begins by outlining the foundational concepts and model characteristics that make machine learning systems particularly susceptible to adversarial manipulation. A structured taxonomy of attack types is presented, including distinctions based on attacker knowledge, goals, timing, and computational frequency. The clinical implications of these attacks are then examined across key radiology tasks, with literature highlighting risks to disease classification, image segmentation and reconstruction, and report generation. Potential downstream consequences such as patient harm, operational disruption, and loss of trust are discussed. Current mitigation strategies are reviewed, spanning input-level defenses, model training modifications, and certified robustness approaches. In parallel, the role of broader lifecycle and safeguard strategies are considered. By consolidating current knowledge across technical and clinical domains, this review helps identify gaps, inform future research priorities, and guide the development of robust, trustworthy AI systems in radiology.</p>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":" ","pages":""},"PeriodicalIF":4.9,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pedro Augusto Gondim Teixeira , Hippolyte Kessler , Lieve Morbée , Nicolas Douis , Fatma Boubaker , Romain Gillet , Alain Blum
{"title":"Mineralized tissue visualization with MRI: Practical insights and recommendations for optimized clinical applications","authors":"Pedro Augusto Gondim Teixeira , Hippolyte Kessler , Lieve Morbée , Nicolas Douis , Fatma Boubaker , Romain Gillet , Alain Blum","doi":"10.1016/j.diii.2024.11.001","DOIUrl":"10.1016/j.diii.2024.11.001","url":null,"abstract":"<div><div>Magnetic resonance imaging (MRI) techniques that enhance the visualization of mineralized tissues (hereafter referred to as MT-MRI) are increasingly being incorporated into clinical practice, particularly in musculoskeletal imaging. These techniques aim to mimic the contrast provided by computed tomography (CT), while taking advantage of MRI's superior soft tissue contrast and lack of ionizing radiation. However, the variety of MT-MRI techniques, including three-dimensional gradient-echo, ultra-short and zero-echo time, susceptibility-weighted imaging, and artificial intelligence-generated synthetic CT, each offer different technical characteristics, advantages, and limitations. Understanding these differences is critical to optimizing clinical application. This review provides a comprehensive overview of the most commonly used MT-MRI techniques, categorizing them based on their technical principles and clinical utility. The advantages and disadvantages of each approach, including their performance in bone morphology assessment, fracture detection, arthropathy-related findings, and soft tissue calcification evaluation are discussed. Additionally, technical limitations and artifacts that may affect image quality and diagnostic accuracy, such as susceptibility effects, signal-to-noise ratio issues, and motion artifacts are addressed. Despite promising developments, MT-MRI remains inferior to conventional CT for evaluating subtle bone abnormalities and soft tissue calcification due to spatial resolution limitations. However, advances in deep learning and hardware innovations, such as artificial intelligence-generated synthetic CT and ultrahigh-field MRI, may bridge this gap in the future.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 5","pages":"Pages 147-156"},"PeriodicalIF":4.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cinematic rendering of transcatheter aortic valve replacement-associated infective endocarditis","authors":"Taha M. Ahmed, Elliot K. Fishman","doi":"10.1016/j.diii.2025.03.005","DOIUrl":"10.1016/j.diii.2025.03.005","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 5","pages":"Pages 196-197"},"PeriodicalIF":4.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clément Marcelin , Amandine Crombé , Eva Jambon , Grégoire Robert , Franck Bladou , Pierre Bour , Thibaut Faller , Valéry Ozenne , Nicolas Grenier , Bruno Quesson
{"title":"Real-time multislice MR-thermometry of the prostate: Assessment of feasibility, accuracy and sources of biases in patients","authors":"Clément Marcelin , Amandine Crombé , Eva Jambon , Grégoire Robert , Franck Bladou , Pierre Bour , Thibaut Faller , Valéry Ozenne , Nicolas Grenier , Bruno Quesson","doi":"10.1016/j.diii.2024.11.006","DOIUrl":"10.1016/j.diii.2024.11.006","url":null,"abstract":"<div><h3>Purpose</h3><div>The primary purpose of this study was to evaluate the accuracy of an MR-thermometry sequence for monitoring prostate temperature. The secondary purposes were to analyze clinical and technical factors that may affect accuracy and testing the method in a realistic setting, with MR-guided Laser ablation on an <em>ex vivo</em> muscle sample.</div></div><div><h3>Materials and methods</h3><div>An <em>ex vivo</em> muscle sample was subjected to Laser ablation while using a two-dimensional multislice segmented echo planar imaging sequence for MR thermometry. The MR thermometry measurements were compared with invasive sensor temperature readings to assess accuracy. Subsequently, 56 men with a median age of 70 years (age range: 53–84 years) who underwent prostate MRI examinations at 1.5- (<em>n</em> = 27) or 3 T (<em>n</em> = 24) were prospectively included. For each patient, the proportion of 'noisy voxels' (i.e., those with a temporal standard deviation of temperature [SD(T)] > 2 °C) in the prostate was calculated. The impact of clinical and technical factors on the proportion of noisy voxels was also examined.</div></div><div><h3>Results</h3><div>MR-thermometry showed excellent correlation with invasive sensors during MR-guided Laser ablation on the <em>ex vivo</em> muscle sample. The median proportion of noisy voxels per patient in the entire cohort was 1 % (Q1, 0.2; Q3, 4.9; range: 0–90.4). No significant differences in median proportion of noisy voxels were observed between examinations performed at 1.5 T and those at 3 T (<em>P</em> = 0.89 before and after adjustment). No clinical or technical factors significantly influenced the proportion of noisy voxels.</div></div><div><h3>Conclusion</h3><div>Two-dimensional real time multislice MR-thermometry is feasible and accurate for monitoring prostate temperature in patients.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 5","pages":"Pages 183-191"},"PeriodicalIF":4.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improved myocardial scar visualization using free-breathing motion-corrected wideband black-blood late gadolinium enhancement imaging in patients with implantable cardiac devices","authors":"Pauline Gut , Hubert Cochet , Panagiotis Antiochos , Guido Caluori , Baptiste Durand , Marion Constantin , Konstantinos Vlachos , Kalvin Narceau , Ambra Masi , Jürg Schwitter , Frederic Sacher , Pierre Jaïs , Matthias Stuber , Aurélien Bustin","doi":"10.1016/j.diii.2024.12.001","DOIUrl":"10.1016/j.diii.2024.12.001","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to introduce and evaluate a novel 2D wideband black-blood (BB) LGE sequence, incorporating wideband inversion recovery, wideband T2 preparation, and non-rigid motion correction (MOCO) reconstruction, to improve myocardial scar detection and address artifacts associated with implantable cardioverter defibrillators (ICDs).</div></div><div><h3>Materials and methods</h3><div>The wideband MOCO free-breathing BB-LGE sequence was tested on a sheep with ischemic scar and in 22 patients with cardiac disease, including 15 with cardiac implants, at 1.5T. Wideband MOCO free-breathing BB-LGE sequence was compared with conventional and wideband breath-held PSIR-LGE and conventional and wideband breath-held BB-LGE techniques. Image sharpness, entropy, and scar-to-blood, scar-to-myocardium, and blood-to-myocardium contrast were analyzed and reconstruction times were measured. Two expert readers assessed the image quality, ICD artifact severity, and the diagnostic confidence with scar extent. Finally, for the animal study, a histology of the heart was performed to confirm the presence and localization of scar tissue.</div></div><div><h3>Results</h3><div>In the animal, wideband MOCO free-breathing BB-LGE were reconstructed in 0.6 s and demonstrated a 200 % improvement in scar-to-blood contrast compared to wideband breath-held PSIR-LGE, with significant improvement in image sharpness and reduction in entropy. It also effectively minimized ICD artifacts and accurately detected scars. In patients, wideband MOCO free-breathing BB-LGE were reconstructed in 1.5 ± 0.4 (standard deviation) s per slice. Seventeen patients (17/22; 77%) with myocardial scars were confidently diagnosed with wideband MOCO free-breathing BB-LGE, compared to 11 (11/22; 50 %) with wideband breath-held PSIR-LGE (<em>P</em> < 0.01).</div></div><div><h3>Conclusion</h3><div>Free-breathing wideband T2-prepared black-blood LGE imaging, combined with motion-corrected reconstruction, offers a promising diagnostic approach for the evaluation of myocardial lesions in patients with ICDs.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 5","pages":"Pages 169-182"},"PeriodicalIF":4.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142819643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Robotics and artificial intelligence in the real world of interventional radiology: Innovation or illusion?","authors":"Baptiste Bonnet , Lambros Tselikas","doi":"10.1016/j.diii.2025.01.006","DOIUrl":"10.1016/j.diii.2025.01.006","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 5","pages":"Pages 145-146"},"PeriodicalIF":4.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myocardial scar detection in patients with implantable cardiac device: Wideband free-breathing motion-corrected black-blood late gadolinium enhancement could be the answer","authors":"Farah Cadour , Benjamin Longère","doi":"10.1016/j.diii.2025.01.002","DOIUrl":"10.1016/j.diii.2025.01.002","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 5","pages":"Pages 143-144"},"PeriodicalIF":4.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francois H. Cornelis , Dimitrios K Filippiadis , Philipp Wiggermann , Stephen B. Solomon , David C. Madoff , Laurent Milot , Sylvain Bodard
{"title":"Evaluation of navigation and robotic systems for percutaneous image-guided interventions: A novel metric for advanced imaging and artificial intelligence integration","authors":"Francois H. Cornelis , Dimitrios K Filippiadis , Philipp Wiggermann , Stephen B. Solomon , David C. Madoff , Laurent Milot , Sylvain Bodard","doi":"10.1016/j.diii.2025.01.004","DOIUrl":"10.1016/j.diii.2025.01.004","url":null,"abstract":"<div><h3>Purpose</h3><div>Navigation and robotic systems aim to improve the accuracy and efficiency of percutaneous image-guided interventions, but the evaluation of their autonomy and integration of advanced imaging and artificial intelligence (AI) is lacking. The purpose of this study was to evaluate the level of automation and integration of advanced imaging and artificial intelligence in navigation and robotic systems for percutaneous image-guided interventions, using established and novel metrics to categorize and compare their capabilities.</div></div><div><h3>Materials and methods</h3><div>Following PRISMA guidelines, a systematic review was conducted to identify studies on clinically validated navigation and robotic systems published between 2000 and May 2024. The PubMed, Embase, Cochrane Library, and Web of Science databases were searched. Data on navigation devices were extracted and analyzed. The levels of autonomy in surgical robotics (LASR) classification system (from 1 to 5) was used to analyze automation. A novel taxonomy, the Levels of Integration of Advanced Imaging and AI (LIAI2) classification system, was created to categorize the integration of imaging technologies and AI (from 1 to 5). These two scores were combined into an aggregate score (from 1 to 10) to reflect the autonomy in percutaneous image-guided intervention.</div></div><div><h3>Results</h3><div>The review included 20 studies assessing two navigation systems and eight robotic devices. The median LASR score was 1 (Q1, Q3: 1, 1), the median LIAI2 score was 2 (Q1, Q3: 2, 3), and the median aggregate score was 3 (Q1, Q3: 3, 4). Only one robotic system (10 % of those reviewed) achieved the highest LASR qualification in the literature, a level 2/5. Four systems (40 %) shared the highest rating for LIAI2, which was a score of 3/5. Four systems (40 %) achieved the highest aggregate scores of 4/10.</div></div><div><h3>Conclusion</h3><div>None of the navigation and robotic systems achieved full autonomy for percutaneous image-guided intervention. The LASR and LIAI2 scales can guide innovation by identifying areas for further development and integration.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 5","pages":"Pages 157-168"},"PeriodicalIF":4.9,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maxime Barat , Camille Ollivier , Linda Taibi , Véronique Nitsche , Philippe Sogni , Philippe Soyer , Lucia Parlati , Anthony Dohan , Hendy Abdoul , Marie-Pierre Revel
{"title":"Standard of care versus standard of care plus Ericksonian hypnosis for percutaneous liver biopsy: Results of a randomized control trial","authors":"Maxime Barat , Camille Ollivier , Linda Taibi , Véronique Nitsche , Philippe Sogni , Philippe Soyer , Lucia Parlati , Anthony Dohan , Hendy Abdoul , Marie-Pierre Revel","doi":"10.1016/j.diii.2024.09.009","DOIUrl":"10.1016/j.diii.2024.09.009","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to compare levels of pain and anxiety during percutaneous ultrasound-guided liver biopsy between patients receiving standard of care and those receiving standard of care plus the support of Ericksonian hypnosis.</div></div><div><h3>Materials and methods</h3><div>This prospective, single-center, single-blind, randomized controlled superiority trial included 70 participants. Participants were randomly assigned to either the standard of care group and received oral anxiolytic medications with reassuring conversational support, or to the experimental group, and received Ericksonian hypnosis (<em>i.e., conversational hypnosis</em>) in addition to standard of care. The primary outcome was the level of pain experienced during the biopsy, measured on a 10-point visual analog scale (0 indicating no pain to 10 indicating excruciating pain). Secondary outcomes included anxiety level during the biopsy, pain level within one hour of the biopsy measured using the same 10-point visual analog scale, amount of analgesic medication taken in the 24 h following the biopsy, and patient willingness to undergo another ultrasound-guided percutaneous liver biopsy in the future.</div></div><div><h3>Results</h3><div>Thirty-six participants were included in the standard of care group, and 34 were included in the experimental group. The mean score of pain experienced during the biopsy was lower in the experimental group (2.4 ± 1.9 [standard deviation (SD)]) compared to the standard of care group (4.4 ± 2.6 [SD]) (<em>P</em> = 0.001). The level of anxiety experienced during the biopsy was lower in the hypnosis group (2.1 ± 1.8 [SD]) compared to the standard of care group (4.8 ± 2.4 [SD]) (<em>P</em> < 0.001). No significant differences in other secondary outcomes were observed between the two groups.</div></div><div><h3>Conclusion</h3><div>The addition of Ericksonian hypnosis to standard of care reduces the pain experienced by patients during percutaneous ultrasound-guided percutaneous liver biopsy by comparison with standard of care alone.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 3","pages":"Pages 93-97"},"PeriodicalIF":4.9,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142367076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}