Diagnostic and Interventional Imaging最新文献

{"title":"3D post-processing in postmortem forensic imaging: Techniques, applications, and future directions","authors":"Nicolas Douis ,&nbsp;Elodie Marchand ,&nbsp;Gwendoline Wary ,&nbsp;Romain Gillet ,&nbsp;Martin Kolopp ,&nbsp;Alain Blum ,&nbsp;Laurent Martrille","doi":"10.1016/j.diii.2025.05.007","DOIUrl":"10.1016/j.diii.2025.05.007","url":null,"abstract":"<div><div>Three-dimensional (3D) post-processing is now an essential part of postmortem forensic computed tomography (CT) imaging. Recent advances in this field include the development of sophisticated reconstruction algorithms, such as global illumination rendering. These tools enable the photorealistic, synthetic, and selective visualization of complex anatomical information with high degrees of accuracy. This technology is particularly valuable in bone injury cases because it facilitates lesion mechanism analysis. 3D representations are valuable tools in forensic investigations, including radiological analysis, communicating results, preparing autopsies, and presenting forensic findings in court. Several factors influence the quality of the final 3D representation, including the technical parameters of CT data acquisition and the appropriate use of post-processing software. This review provides an overview of the key factors that determine the quality of 3D forensic CT images, examines their applications and limitations, and discusses future directions.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 10","pages":"Pages 337-344"},"PeriodicalIF":8.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal artificial intelligence in radiology: Text-dominant reasoning limits image understanding","authors":"Loïc Duron ,&nbsp;Augustin Lecler","doi":"10.1016/j.diii.2025.05.008","DOIUrl":"10.1016/j.diii.2025.05.008","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 10","pages":"Pages 333-334"},"PeriodicalIF":8.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The continued industrial use of ethylene oxide despite health risks: An interventional radiology perspective on a broader medical challenge of balancing sterility, safety, and sustainability","authors":"Julien Ognard ,&nbsp;Marie Schmidt ,&nbsp;Christophe Paya ,&nbsp;Isabelle Le Du ,&nbsp;Camille Bourillon ,&nbsp;Mourad Cheddad El Aouni ,&nbsp;Ludwig Serge Aho Glele ,&nbsp;Riitta Rautio ,&nbsp;Sara Lojo-Lendoiro ,&nbsp;Omer F. Eker ,&nbsp;Vanessa Brun ,&nbsp;Xianli Lv ,&nbsp;Erwan L’Her ,&nbsp;Raphaël Tripier ,&nbsp;Abdelghani Fakhreddine Boustia ,&nbsp;Betty Jean ,&nbsp;Jean-Christophe Gentric ,&nbsp;Cyril Leven ,&nbsp;Douraied Ben Salem","doi":"10.1016/j.diii.2025.05.002","DOIUrl":"10.1016/j.diii.2025.05.002","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 10","pages":"Pages 353-355"},"PeriodicalIF":8.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular management of pelvic congestion syndrome: An expert consensus statement from the French Society of Cardiovascular Imaging (SFICV), Interventional Radiology Federation (FRI), College of French Radiology Teachers (CERF), and French Society of Women's Imaging (SIFEM)","authors":"Vincent Le Pennec ,&nbsp;Frédéric Douane ,&nbsp;Jean Luc Brun ,&nbsp;Francine Thouveny ,&nbsp;Thomas Martinelli ,&nbsp;Marine Bravetti ,&nbsp;Charles Mastier ,&nbsp;Yan Le Bras ,&nbsp;André Rogopoulos ,&nbsp;Pierre Antoine Barral ,&nbsp;Henri Marret ,&nbsp;Pascal Chabrot ,&nbsp;Alexis Jacquier ,&nbsp;Quentin Senechal ,&nbsp;Gary Doppelt ,&nbsp;Julien Frandon","doi":"10.1016/j.diii.2025.04.004","DOIUrl":"10.1016/j.diii.2025.04.004","url":null,"abstract":"<div><h3>Purpose</h3><div>Pelvic congestion syndrome (PCS) is a major cause of chronic pelvic pain in women of reproductive age. It is often associated with pelvic venous insufficiency and venous dilatation of the ovarian and uterine veins, resulting in a variety of symptoms exacerbated by venous hypertension. Despite its prevalence, PCS lacks standardized diagnostic and management protocols, making effective treatment challenging. The purpose of this expert consensus statement was to summarize the opinions of French radiologists and gynecologists regarding the diagnosis, imaging, treatment, and management of PCS.</div></div><div><h3>Materials and methods</h3><div>A working group of 14 expert radiologists and gynecologists from various French medical centers used a Delphi panel approach with several rounds of remote and face-to-face meetings to formulate and refine expert opinions based on the current literature and clinical expertise. These opinions were categorized according to diagnostic criteria, imaging techniques, therapeutic options, and follow-up protocols.</div></div><div><h3>Results</h3><div>The group formulated 72 initial opinions, and 65 were retained after rigorous evaluation for consensus. Key diagnostic tools include Doppler ultrasound for detection of venous reflux and magnetic resonance imaging for detailed assessment of venous anatomy. Endovascular embolization was highlighted as the primary treatment approach and recommended after thorough imaging evaluation. Noninvasive treatments and multidisciplinary care were also emphasized for comprehensive management. The expert opinion also included post-treatment follow-up to assess quality of life and symptom resolution.</div></div><div><h3>Conclusion</h3><div>This structured consensus approach helped develop standardized expert opinions on management of, providing clear guidelines for diagnosis, treatment, and follow-up. These guidelines should improve clinical practice and patient care in the management of PCS.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 10","pages":"Pages 356-366"},"PeriodicalIF":8.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling an under-recognized strain: New guidelines for pelvic congestion syndrome","authors":"Maxime Barat ,&nbsp;Philippe Soyer ,&nbsp;Anthony Dohan","doi":"10.1016/j.diii.2025.06.001","DOIUrl":"10.1016/j.diii.2025.06.001","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 10","pages":"Pages 335-336"},"PeriodicalIF":8.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging features of focal nodular hyperplasia on gadoxetic acid-enhanced MRI","authors":"Francesco Matteini ,&nbsp;Valérie Vilgrain ,&nbsp;Maxime Ronot","doi":"10.1016/j.diii.2025.07.007","DOIUrl":"10.1016/j.diii.2025.07.007","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 10","pages":"Pages 367-368"},"PeriodicalIF":8.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between multimodal foundation models and radiologists for the diagnosis of challenging neuroradiology cases with text and images","authors":"Bastien Le Guellec ,&nbsp;Cyril Bruge ,&nbsp;Najib Chalhoub ,&nbsp;Victor Chaton ,&nbsp;Edouard De Sousa ,&nbsp;Yann Gaillandre ,&nbsp;Riyad Hanafi ,&nbsp;Matthieu Masy ,&nbsp;Quentin Vannod-Michel ,&nbsp;Aghiles Hamroun ,&nbsp;Grégory Kuchcinski ,&nbsp;ARIANES investigators","doi":"10.1016/j.diii.2025.04.006","DOIUrl":"10.1016/j.diii.2025.04.006","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to compare the ability of two multimodal models (GPT-4o and Gemini 1.5 Pro) with that of radiologists to generate differential diagnoses from textual context alone, key images alone, or a combination of both using complex neuroradiology cases.</div></div><div><h3>Materials and methods</h3><div>This retrospective study included neuroradiology cases from the \"<em>Diagnosis Please</em>\" series published in the <em>Radiology</em> journal between January 2008 and September 2024. The two multimodal models were asked to provide three differential diagnoses from textual context alone, key images alone, or the complete case. Six board-certified neuroradiologists solved the cases in the same setting, randomly assigned to two groups: context alone first and images alone first. Three radiologists solved the cases without, and then with the assistance of Gemini 1.5 Pro. An independent radiologist evaluated the quality of the image descriptions provided by GPT-4o and Gemini for each case. Differences in correct answers between multimodal models and radiologists were analyzed using McNemar test.</div></div><div><h3>Results</h3><div>GPT-4o and Gemini 1.5 Pro outperformed radiologists using clinical context alone (mean accuracy, 34.0 % [18/53] and 44.7 % [23.7/53] <em>vs</em>. 16.4 % [8.7/53]; both <em>P</em> &lt; 0.01). Radiologists outperformed GPT-4o and Gemini 1.5 Pro using images alone (mean accuracy, 42.0 % [22.3/53] <em>vs</em>. 3.8 % [2/53], and 7.5 % [4/53]; both <em>P</em> &lt; 0.01) and the complete cases (48.0 % [25.6/53] <em>vs</em>. 34.0 % [18/53], and 38.7 % [20.3/53]; both <em>P</em> &lt; 0.001). While radiologists improved their accuracy when combining multimodal information (from 42.1 % [22.3/53] for images alone to 50.3 % [26.7/53] for complete cases; <em>P</em> &lt; 0.01), GPT-4o and Gemini 1.5 Pro did not benefit from the multimodal context (from 34.0 % [18/53] for text alone to 35.2 % [18.7/53] for complete cases for GPT-4o; <em>P</em> = 0.48, and from 44.7 % [23.7/53] to 42.8 % [22.7/53] for Gemini 1.5 Pro; <em>P</em> = 0.54). Radiologists benefited significantly from the suggestion of Gemini 1.5 Pro, increasing their accuracy from 47.2 % [25/53] to 56.0 % [27/53] (<em>P</em> &lt; 0.01). Both GPT-4o and Gemini 1.5 Pro correctly identified the imaging modality in 53/53 (100 %) and 51/53 (96.2 %) cases, respectively, but frequently failed to identify key imaging findings (43/53 cases [81.1 %] with incorrect identification of key imaging findings for GPT-4o and 50/53 [94.3 %] for Gemini 1.5).</div></div><div><h3>Conclusion</h3><div>Radiologists show a specific ability to benefit from the integration of textual and visual information, whereas multimodal models mostly rely on the clinical context to suggest diagnoses.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"106 10","pages":"Pages 345-352"},"PeriodicalIF":8.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of structural predictors of lung function improvement in adults with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor using deep-learning.","authors":"Guillaume Chassagnon, Rafael Marini, Valentin Ong, Jennifer Da Silva, Denis Habip Gatenyo, Isabelle Honore, Reem Kanaan, Nicolas Carlier, Johanna Fesenbeckh, Espérie Burnet, Marie-Pierre Revel, Clémence Martin, Pierre-Régis Burgel","doi":"10.1016/j.diii.2025.09.003","DOIUrl":"https://doi.org/10.1016/j.diii.2025.09.003","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the relationship between structural abnormalities on CT and lung function prior to and after initiation of elexacaftor-tezacaftor-ivacaftor (ETI) in adults with cystic fibrosis (CF) using a deep learning model.</p><p><strong>Materials and methods: </strong>A deep learning quantification model was developed using 100 chest computed tomography (CT) examinations of patients with CF and 150 chest CT examinations of patients with various other bronchial diseases to quantify seven types of abnormalities. This model was then applied to an independent dataset of CT examinations of 218 adults with CF who were treated with ETI. The relationship between structural abnormalities and percent predicted forced expiratory volume in one second (ppFEV₁) was examined using general linear regression models.</p><p><strong>Results: </strong>The deep learning model performed as well as radiologists for the quantification of the seven types of abnormalities. Chest CT examinations obtained before to and one year after the initiation of ETI were analyzed. The independent structural predictors of ppFEV₁ prior to ETI were bronchial wall thickening (P = 0.011), mucus plugging (P < 0.001), consolidation/atelectasis (P < 0.001), and mosaic perfusion (P < 0.001). An increase in ppFEV₁ after initiation of ETI independently correlated with a decrease in bronchial wall thicknening (-49 %; P = 0.004), mucus plugging (-92 %; P < 0.001), centrilobular nodules (-78 %; P = 0.009) and mosaic perfusion (-14 %; P < 0.001). Younger age (P < 0.001), greater mucus plugging extent (P = 0.016), and centrilobular nodules (P < 0.001) prior to ETI initiation were independent predictors of ppFEV₁ improvement.</p><p><strong>Conclusion: </strong>A deep learning model can quantify CT lung abnormalities in adults with CF. Lung function impairment in adults with CF is associated with muco-inflammatory lesions on CT, which are largely reversible with ETI, and with mosaic perfusion, which appear less reversible and is presumably related to irreversible damage. Predictors of lung function improvement are a younger age and a greater extent of muco-inflammatory lesions obstructing the airways.</p>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance of pelvic CT, T1-weighted MRI and mineralized-tissue MRI for the assessment of structural lesions in sacroiliitis in patients with axial spondyloarthritis.","authors":"Romain Gillet, Samy Obeid, Maxime Clara, Gabriela Hossu, Khalid Ambarki, Fatma Boubaker, Pedro Augusto Gondim Teixeira, Alain Blum","doi":"10.1016/j.diii.2025.09.004","DOIUrl":"https://doi.org/10.1016/j.diii.2025.09.004","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the diagnostic capability of mineralized tissue-magnetic resonance imaging (MT-MRI) to detect erosions, sclerosis, and ankylosis of the sacroiliac joint (SIJ) in patients with axial spondyloarthritis, by comparison with T1-weighted MRI and pelvic computed tomography (CT), using SIJ CT as the standard of reference.</p><p><strong>Material and methods: </strong>This retrospective study included 100 patients (62 women, 38 men; mean age, 39.9 ± 14.3 [standard deviation] years; age range: 19-79) with suspected axial spondyloarthritis, who underwent SIJ MRI and CT on the same day between August 2023 and March 2025. Two musculoskeletal radiologists independently scored the amount of structural lesions of SIJs. The diagnostic confidence in each imaging modality was also evaluated.</p><p><strong>Results: </strong>The erosion scores showed no significant difference between SIJ CT and MT-MRI for both readers (P ≥ 0.07) but were lower than those of SIJ CT when using T1-weighted MRI for both readers (P ≤ 0.011). The performance of pelvic CT for depicting erosion was intermediate but closer to that of MT-MRI. The sclerosis scores were 16-20 % lower with T1-weighted MRI than with SIJ CT (P ≤ 0.012) and 3 % lower with MT-MRI (P ≤ 0.04), but 8 % overestimated using pelvic CT (P ≤ 0.001). For both groups, SIJ CT obtained the highest confidence score, which was superior to pelvic CT (P ≤ 0.001), itself superior to T1-weighted MRI and MT-MRI (P ≤ 0.001), with the latter two not differing significantly (P ≥ 0.109).</p><p><strong>Conclusion: </strong>T1-weighted MRI alone is insufficient for reliably evaluating structural lesions of SIJs due to sacroiliitis in patients with axial spondyloarthritis. MT-MRI emerges as the closest alternative to SIJ CT, demonstrating excellent diagnostic performance while eliminating radiation exposure.</p>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transarterial radioembolization versus atezolizumab-bevacizumab for the treatment of hepatocellular carcinoma with portal vein tumor thrombosis.","authors":"Youngsu Park, Yuri Cho, Seung Up Kim, Aryoung Kim, Hyunjae Shin, Hyo-Cheol Kim, In Joon Lee, Gyoung Min Kim, Dongho Hyun, Yunmi Ko, Jeayeon Park, Jae Woong Yoon, Gyung Sun Lim, Moon Haeng Hur, Yun Bin Lee, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon, Jin Wook Chung, Dong Hyun Sinn, Yoon Jun Kim","doi":"10.1016/j.diii.2025.09.002","DOIUrl":"https://doi.org/10.1016/j.diii.2025.09.002","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to compare transarterial radioembolization (TARE) and atezolizumab plus bevacizumab (Atezo/Bev) in treatment-naïve patients with hepatocellular carcinoma (HCC) and portal vein tumor thrombosis (PVTT) without extrahepatic metastasis.</p><p><strong>Material and methods: </strong>This multicenter retrospective study evaluated 213 patients initially treated with TARE or Atezo/Bev between 2016 and 2023. The primary outcome was overall survival, and the secondary outcomes were progression-free survival, objective response rate, and safety. Baseline characteristics were adjusted using inverse probability treatment weighting or propensity score matching.</p><p><strong>Results: </strong>Deaths occurred in 36 out of 125 patients (28.8 %) in the TARE group and 57 out of 88 patients (64.8 %) in the Atezo/Bev group. The median overall survival was significantly longer in the TARE grouop (27.5 months) than in the Atezo/Bev group (8.6 months) (P < 0.01), consistent across analyses before matching (hazard ratio [HR], 0.38; 95% confidence interval [CI]: 0.25-0.58; P < 0.01), after inverse probability treatment weighting (HR, 0.49; 95 % CI: 0.28-0.85; P = 0.01), and after propensity score matching (HR, 0.40; 95% CI: 0.22-0.74; P < 0.01). In the PVTT subgroup involving segmental to lobar branches (Vp1-3), TARE demonstrated prolonged overall survival (HR, 0.36; 95 % CI: 0.20-0.63; P < 0.01), with no significant difference in patients with Vp4. The TARE and Atezo/Bev groups exhibited similar progression-free survival. No significant differences in objective response rate were found between TARE group (22.2-30.9 %) and Atezo/Bev group (30.6-30.9 %). Adverse events were less frequent in the TARE group than in the Atezo/Bev group. The incidence of grade ≥ 2 ascites and variceal bleeding were significantly lower in the TARE group (12.0 % and 1.7 %, respectively) than in the Atezo/Bev group (20.5 % and 8 %, respectively) (both P < 0.05). No significant differences in Child-Pugh score aggravation of ≥ 2 were observed between the TARE group (14.4 %) and the Atezo/Bev group (25 %) (P = 0.08).</p><p><strong>Conclusion: </strong>For patients with preserved liver function and locally advanced HCC involving segmental or lobar PVTT, TARE may be preferable to Atezo/Bev.</p>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":" ","pages":""},"PeriodicalIF":8.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145151320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}