Xue Wang , Lijuan Wang , Yating Wu , Xiang Lv , Yao Xu , Weiqiang Dou , Hongying Zhang , Jingtao Wu , Song'an Shang
{"title":"Intracerebral hemodynamic abnormalities in patients with Parkinson's disease: Comparison between multi-delay arterial spin labelling and conventional single-delay arterial spin labelling","authors":"Xue Wang , Lijuan Wang , Yating Wu , Xiang Lv , Yao Xu , Weiqiang Dou , Hongying Zhang , Jingtao Wu , Song'an Shang","doi":"10.1016/j.diii.2024.01.006","DOIUrl":"10.1016/j.diii.2024.01.006","url":null,"abstract":"<div><h3>Purpose</h3><p>The purpose of this study was to analyze the intracerebral abnormalities of hemodynamics in patients with Parkinson's disease (PD) through arterial spin labelling (ASL) technique with multi-delay ASL (MDASL) and conventional single-delay ASL (SDASL) protocols and to verify the potential clinical application of these features for the diagnosis of PD.</p></div><div><h3>Materials and methods</h3><p>Perfusion data of the brain obtained using MDASL and SDASL in patients with PD were compared to those obtained in healthy control (HC) subjects. Intergroup comparisons of z-scored cerebral blood flow (zCBF), arterial transit time (zATT) and cerebral blood volume (zCBV) were performed via voxel-based analysis. Performance of these perfusion metrics were estimated using area under the receiver operating characteristic curve (AUC) and compared using Delong test.</p></div><div><h3>Results</h3><p>A total of 47 patients with PD (29 men; 18 women; mean age, 69.0 ± 7.6 (standard deviation, [SD]) years; range: 50.0−84.0 years) and 50 HC subjects (28 men; 22 women; mean age, 70.1 ± 6.2 [SD] years; range: 50.0−93.0 years) were included. Relative to the uncorrected-zCBF map, the corrected-zCBF map further refined the distributed brain regions in the PD group versus the HC group, manifested as the extension of motor-related regions (<em>P</em><sub>FWE</sub> < 0.001). Compared to the HC subjects, patients with PD had elevated zATT and zCBV in the right putamen, a shortened zATT in the superior frontal gyrus, and specific zCBV variations in the left precuneus and the right supplementary motor area (<em>P</em><sub>FWE</sub> < 0.001). The corrected-zCBF (AUC, 0.90; 95% confidence interval [CI]: 0.84−0.96) showed better classification performance than uncorrected-zCBF (AUC, 0.84; 95% CI: 0.75−0.92) (<em>P</em> = 0.035). zCBV achieved an AUC of 0.89 (95% CI: 0.82−0.96) and zATT achieved an AUC of 0.66 (95% CI: 0.55−0.77). The integration model of hemodynamic features from MDASL provided improved performance (AUC, 0.97; 95% CI: 0.95−0.98) for the diagnosis of PD by comparison with each perfusion model (<em>P</em> < 0.001).</p></div><div><h3>Conclusion</h3><p>ASL identifies impaired hemodynamics in patients with PD including regional abnormalities of CBF, CBV and ATT, which can better be mapped with MDASL compared to SDASL. These findings provide complementary depictions of perfusion abnormalities in patients with PD and highlight the clinical feasibility of MDASL.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 7","pages":"Pages 281-291"},"PeriodicalIF":4.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139680227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chang-Hui Xiao , Peng Liu , Hui-Hui Zhang , Fan Yang , Xiang Chen , Feng Huang , Jian-bin Liu , Xian-Zheng Tan
{"title":"Incremental diagnostic value of virtual non-contrast dual-energy CT for the diagnosis of choledocholithiasis over conventional unenhanced CT","authors":"Chang-Hui Xiao , Peng Liu , Hui-Hui Zhang , Fan Yang , Xiang Chen , Feng Huang , Jian-bin Liu , Xian-Zheng Tan","doi":"10.1016/j.diii.2024.02.004","DOIUrl":"10.1016/j.diii.2024.02.004","url":null,"abstract":"<div><h3>Purpose</h3><p>The purpose of this study was to evaluate the incremental diagnostic value of virtual non-contrast (VNC) images derived from unenhanced dual-energy computed tomography (CT) for the diagnosis of choledocholithiasis by comparison with conventional unenhanced CT.</p></div><div><h3>Materials and methods</h3><p>Eighty-nine patients with gallbladder stones who had undergone both abdominal unenhanced dual-energy CT and magnetic resonance cholangiopancreatography (MRCP) were retrospectively included. There were 53 men and 36 women, with a mean age of 54 ± 13 (standard deviation) years (age range: 41–67 years). VNC and conventional CT images were generated. Two independent radiologists evaluated the presence of choledocholithiasis in three reading sessions (session 1, conventional unenhanced CT images; session 2, VNC images; session 3, conventional unenhanced CT plus VNC images). The reading time to identify choledocholithiasis was recorded. Inter-reader agreement was measured by using the Cohen kappa (κ) test. Incremental diagnostic value of VNC imaging when combined with conventional unenhanced CT was assessed based on discrimination (area under the curve [AUC]) and clinical utility (decision curve analysis). The diagnostic performance of dual-energy CT and that of MRCP were compared using DeLong test.</p></div><div><h3>Results</h3><p>Using the standard of reference, 39 patients (39/89; 44%) had choledocholithiasis. The diagnosis of choledocholithiasis was improved using VNC images in combination with conventional unenhanced CT (AUC, 0.877; 95% confidence interval [CI]: 0.808, 0.947) by comparison with conventional unenhanced CT alone (AUC, 0.789; 95% CI: 0.718, 0.877) (<em>P</em> = 0.033) and achieved almost perfect inter-reader agreement (κ = 0.88; 95% CI: 0.72, 1.00) for the diagnosis of choledocholithiasis, without lengthening the median reading time (16.2 s for the combination of conventional CT and VNC images <em>vs.</em> 14.7 s for conventional CT alone; <em>P</em> <em>=</em> 0<em>.</em>325). Based on decision curve analysis, adding VNC imaging to conventional unenhanced CT resulted in a higher net benefit among most of decision thresholds. No differences in diagnostic performance were found between the combination of conventional unenhanced CT and VNC imaging (AUC, 0.877; 95% CI: 0.808, 0.947) and MRCP (AUC, 0.913; 95% CI: 0.852, 0.974) (<em>P</em> <em>=</em> 0<em>.</em>458).</p></div><div><h3>Conclusions</h3><p>VNC images derived from dual-energy unenhanced CT have incremental diagnostic value for the diagnosis of choledocholithiasis. Unenhanced CT in a dual-energy mode may be a useful tool for the diagnosis of choledocholithiasis.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 7","pages":"Pages 292-298"},"PeriodicalIF":4.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211568424000391/pdfft?md5=4c5706cf63ae66a8b87affdf7553a8ee&pid=1-s2.0-S2211568424000391-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139913800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The trade-off dilemma between radiation dose and image resolution","authors":"","doi":"10.1016/j.diii.2024.06.006","DOIUrl":"10.1016/j.diii.2024.06.006","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 351-352"},"PeriodicalIF":4.9,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Next-generation oncology radiotracers for a promising personalized medicine","authors":"","doi":"10.1016/j.diii.2024.06.003","DOIUrl":"10.1016/j.diii.2024.06.003","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 347-348"},"PeriodicalIF":4.9,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Apparent diffusion coefficient analysis of solid tissue helps distinguish borderline from invasive malignant adnexal masses rated O-RADS MRI 4","authors":"","doi":"10.1016/j.diii.2024.05.004","DOIUrl":"10.1016/j.diii.2024.05.004","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to evaluate the contribution of apparent diffusion coefficient (ADC) analysis of the solid tissue of adnexal masses to optimize tumor characterization and possibly refine the risk stratification of the O-RADS MRI 4 category.</div></div><div><h3>Materials and methods</h3><div>The EURAD cohort was retrospectively analyzed to select all patients with an adnexal mass with solid tissue and feasible ADC measurements. Two radiologists independently measured the ADC values of solid tissue, excluding necrotic areas, surrounding structures, and magnetic susceptibility artifacts. Significant differences in diffusion quantitative parameters in the overall population and according to the morphological aspect of solid tissue were analyzed to identify its impact on ADC reliability. Receiver operating characteristics curve (ROC) was used to determine the optimum cutoff of the ADC for distinguishing invasive from non-invasive tumors in the O-RADS MRI score 4 population.</div></div><div><h3>Results</h3><div>The final study population included 180 women with a mean age of 57 ± 15.5 (standard deviation) years; age range: 19–95 years) with 93 benign, 23 borderline, and 137 malignant masses. The median ADC values of solid tissue was greater in borderline masses (1.310 × 10<sup>−3</sup> mm<sup>2</sup>/s (Q1, Q3: 1.152, 1.560 × 10<sup>−3</sup> mm<sup>2</sup>/s) than in benign masses (1.035 × 10<sup>−3</sup> mm<sup>2</sup>/s; Q1, Q3: 0.900, 1.560 × 10<sup>−3</sup> mm<sup>2</sup>/s) (<em>P</em> <em>=</em> 0.002) and in benign tumors compared by comparison with invasive masses (0.850 × 10<sup>−3</sup> mm<sup>2</sup>/s; Q1, Q3: 0.750, 0.990 × 10<sup>−3</sup> mm<sup>2</sup>/s) (<em>P</em> < 0.001). Solid tissue corresponded to irregular septa or papillary projection in 18.6% (47/253), to a mural nodule or a mixed mass in 46.2% (117/253), and to a purely solid mass in 35.2% (89/253) of adnexal masses. In mixed masses or masses with mural nodule subgroup, invasive masses had a significantly lower ADC (0.830 × 10<sup>−3</sup> mm<sup>2</sup>/s (Q1, Q3: 0.738, 0.960) than borderline (1.385; Q1, Q3: 1.300, 1.930) (<em>P</em> <em>=</em> 0.0012) and benign masses (<em>P</em> <em>=</em> 0.04). An ADC cutoff of 1.08 × 10<sup>−3</sup> mm<sup>2</sup>/s yielded 71.4% sensitivity and 100% specificity for identifying invasive lesions in the mixed or mural nodule subgroup with an AUC of 0.92 (95% confidence interval: 0.76–0.99).</div></div><div><h3>Conclusion</h3><div>ADC analysis of solid tissue of adnexal masses could help distinguish invasive masses within the O-RADS MRI 4 category, especially in mixed masses or those with mural nodule.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 386-394"},"PeriodicalIF":4.9,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141327992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving image quality of the middle ear with ultra-high-resolution CT coupled with deep-learning image reconstruction algorithm","authors":"Joël Greffier, Philippe Soyer, Djamel Dabli","doi":"10.1016/j.diii.2024.02.006","DOIUrl":"10.1016/j.diii.2024.02.006","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 6","pages":"Pages 211-212"},"PeriodicalIF":5.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139941052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alfredo Páez-Carpio , Ivan Vollmer , Federico X. Zarco , Mario Matute-González , Blanca Domenech-Ximenos , Elena Serrano , Joan A. Barberà , Isabel Blanco , Fernando M. Gómez
{"title":"Imaging of chronic thromboembolic pulmonary hypertension before, during and after balloon pulmonary angioplasty","authors":"Alfredo Páez-Carpio , Ivan Vollmer , Federico X. Zarco , Mario Matute-González , Blanca Domenech-Ximenos , Elena Serrano , Joan A. Barberà , Isabel Blanco , Fernando M. Gómez","doi":"10.1016/j.diii.2024.02.005","DOIUrl":"10.1016/j.diii.2024.02.005","url":null,"abstract":"<div><p>Balloon pulmonary angioplasty (BPA) has recently been elevated as a class I recommendation for the treatment of inoperable or residual chronic thromboembolic pulmonary hypertension (CTEPH). Proper patient selection, procedural safety, and post-procedural evaluation are crucial in the management of these patients, with imaging work-up playing a pivotal role. Understanding the diagnostic and therapeutic imaging algorithms of CTEPH, the imaging features of patients amenable to BPA, all imaging findings observed during and immediately after the procedure and the changes observed during the follow-up is crucial for all interventional radiologists involved in the care of patients with CTEPH. This article illustrates the imaging work-up of patients with CTEPH amenable to BPA, the imaging findings observed before, during and after BPA, and provides a detailed description of all imaging modalities available for CTEPH evaluation.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 6","pages":"Pages 215-226"},"PeriodicalIF":5.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211568424000408/pdfft?md5=e985f4e57d0266a1c4dc08eb7fd99493&pid=1-s2.0-S2211568424000408-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139984178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is robotic assistance the future of percutaneous interventional radiology?","authors":"Maxime Barat , Laurent Milot","doi":"10.1016/j.diii.2024.01.007","DOIUrl":"10.1016/j.diii.2024.01.007","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 6","pages":"Pages 209-210"},"PeriodicalIF":5.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139974096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baptiste Bonnet , Thierry de Baère , Paul Beunon , Adlane Feddal , Lambros Tselikas , Frédéric Deschamps
{"title":"Robotic-assisted CT-guided percutaneous thermal ablation of abdominal tumors: An analysis of 41 patients","authors":"Baptiste Bonnet , Thierry de Baère , Paul Beunon , Adlane Feddal , Lambros Tselikas , Frédéric Deschamps","doi":"10.1016/j.diii.2024.01.005","DOIUrl":"10.1016/j.diii.2024.01.005","url":null,"abstract":"<div><h3>Purpose</h3><p>Robotic assistance is rapidly evolving and may help physicians optimize needle guidance during percutaneous interventions. The purpose of the study was to report feasibility, safety, accuracy, immediate clinical success and short-term local tumor control after robotic-assisted computed tomography (CT)-guided thermal ablation of abdominal tumors.</p></div><div><h3>Materials and methods</h3><p>Forty-one patients who underwent percutaneous thermal ablation of abdominal tumors using robotic-assisted CT-guided were included. All ablations were performed with robotic assistance, using an optically-monitored robotic system with a needle guide sent to preplanned trajectories defined on three-dimensional-volumetric CT acquisitions with respiration monitoring. Endpoints were technical success, safety, distance from needle tip to planned trajectory and number of needle adjustments, and complete ablation rate.</p></div><div><h3>Results</h3><p>Forty-one patients (31 men; mean age, 66.7 ± 9.9 [standard deviation (SD)] years [age range: 41–84 years]) were treated for 48 abdominal tumors, with 79 planned needles. Lesions treated were located in the liver (23/41; 56%), kidney (14/41;34%), adrenal gland (3/41; 7%) or retroperitoneum (1/41; 2%). Technical success was achieved in 39/41 (95%) patients, and 76/79 (96%) needle insertions. The mean lateral distance between the needle tip and planned trajectory was 3.2 ± 4.5 (SD) mm (range: 0–20 mm) before adjustments, and the mean three-dimensional distance was 1.6 ± 2.6 (SD) mm (range: 0–13 mm) after 29 manual depth adjustments (29/78; 37%) and 33 lateral adjustments (33/78; 42%). Two (2/79; 3%) needles required complete manual reinsertion. One grade 3 complication was reported in one patient (1/41; 2%). The overall clinical success rate was 100%. The 3-month local tumor control rate (progression free survival) was 95% (38/41).</p></div><div><h3>Conclusion</h3><p>These results provide further evidence on the use of robotic-assisted needle insertion regarding feasibility, safety, and accuracy, resulting in effective percutaneous thermal ablation of abdominal tumors.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 6","pages":"Pages 227-232"},"PeriodicalIF":5.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211568424000172/pdfft?md5=3540210314c1be55dde8740f2f9d66c3&pid=1-s2.0-S2211568424000172-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139898308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}