{"title":"Apparent diffusion coefficient analysis of solid tissue helps distinguish borderline from invasive malignant adnexal masses rated O-RADS MRI 4","authors":"","doi":"10.1016/j.diii.2024.05.004","DOIUrl":"10.1016/j.diii.2024.05.004","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to evaluate the contribution of apparent diffusion coefficient (ADC) analysis of the solid tissue of adnexal masses to optimize tumor characterization and possibly refine the risk stratification of the O-RADS MRI 4 category.</div></div><div><h3>Materials and methods</h3><div>The EURAD cohort was retrospectively analyzed to select all patients with an adnexal mass with solid tissue and feasible ADC measurements. Two radiologists independently measured the ADC values of solid tissue, excluding necrotic areas, surrounding structures, and magnetic susceptibility artifacts. Significant differences in diffusion quantitative parameters in the overall population and according to the morphological aspect of solid tissue were analyzed to identify its impact on ADC reliability. Receiver operating characteristics curve (ROC) was used to determine the optimum cutoff of the ADC for distinguishing invasive from non-invasive tumors in the O-RADS MRI score 4 population.</div></div><div><h3>Results</h3><div>The final study population included 180 women with a mean age of 57 ± 15.5 (standard deviation) years; age range: 19–95 years) with 93 benign, 23 borderline, and 137 malignant masses. The median ADC values of solid tissue was greater in borderline masses (1.310 × 10<sup>−3</sup> mm<sup>2</sup>/s (Q1, Q3: 1.152, 1.560 × 10<sup>−3</sup> mm<sup>2</sup>/s) than in benign masses (1.035 × 10<sup>−3</sup> mm<sup>2</sup>/s; Q1, Q3: 0.900, 1.560 × 10<sup>−3</sup> mm<sup>2</sup>/s) (<em>P</em> <em>=</em> 0.002) and in benign tumors compared by comparison with invasive masses (0.850 × 10<sup>−3</sup> mm<sup>2</sup>/s; Q1, Q3: 0.750, 0.990 × 10<sup>−3</sup> mm<sup>2</sup>/s) (<em>P</em> < 0.001). Solid tissue corresponded to irregular septa or papillary projection in 18.6% (47/253), to a mural nodule or a mixed mass in 46.2% (117/253), and to a purely solid mass in 35.2% (89/253) of adnexal masses. In mixed masses or masses with mural nodule subgroup, invasive masses had a significantly lower ADC (0.830 × 10<sup>−3</sup> mm<sup>2</sup>/s (Q1, Q3: 0.738, 0.960) than borderline (1.385; Q1, Q3: 1.300, 1.930) (<em>P</em> <em>=</em> 0.0012) and benign masses (<em>P</em> <em>=</em> 0.04). An ADC cutoff of 1.08 × 10<sup>−3</sup> mm<sup>2</sup>/s yielded 71.4% sensitivity and 100% specificity for identifying invasive lesions in the mixed or mural nodule subgroup with an AUC of 0.92 (95% confidence interval: 0.76–0.99).</div></div><div><h3>Conclusion</h3><div>ADC analysis of solid tissue of adnexal masses could help distinguish invasive masses within the O-RADS MRI 4 category, especially in mixed masses or those with mural nodule.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 386-394"},"PeriodicalIF":4.9,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141327992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving image quality of the middle ear with ultra-high-resolution CT coupled with deep-learning image reconstruction algorithm","authors":"Joël Greffier, Philippe Soyer, Djamel Dabli","doi":"10.1016/j.diii.2024.02.006","DOIUrl":"10.1016/j.diii.2024.02.006","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 6","pages":"Pages 211-212"},"PeriodicalIF":5.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139941052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alfredo Páez-Carpio , Ivan Vollmer , Federico X. Zarco , Mario Matute-González , Blanca Domenech-Ximenos , Elena Serrano , Joan A. Barberà , Isabel Blanco , Fernando M. Gómez
{"title":"Imaging of chronic thromboembolic pulmonary hypertension before, during and after balloon pulmonary angioplasty","authors":"Alfredo Páez-Carpio , Ivan Vollmer , Federico X. Zarco , Mario Matute-González , Blanca Domenech-Ximenos , Elena Serrano , Joan A. Barberà , Isabel Blanco , Fernando M. Gómez","doi":"10.1016/j.diii.2024.02.005","DOIUrl":"10.1016/j.diii.2024.02.005","url":null,"abstract":"<div><p>Balloon pulmonary angioplasty (BPA) has recently been elevated as a class I recommendation for the treatment of inoperable or residual chronic thromboembolic pulmonary hypertension (CTEPH). Proper patient selection, procedural safety, and post-procedural evaluation are crucial in the management of these patients, with imaging work-up playing a pivotal role. Understanding the diagnostic and therapeutic imaging algorithms of CTEPH, the imaging features of patients amenable to BPA, all imaging findings observed during and immediately after the procedure and the changes observed during the follow-up is crucial for all interventional radiologists involved in the care of patients with CTEPH. This article illustrates the imaging work-up of patients with CTEPH amenable to BPA, the imaging findings observed before, during and after BPA, and provides a detailed description of all imaging modalities available for CTEPH evaluation.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 6","pages":"Pages 215-226"},"PeriodicalIF":5.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211568424000408/pdfft?md5=e985f4e57d0266a1c4dc08eb7fd99493&pid=1-s2.0-S2211568424000408-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139984178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is robotic assistance the future of percutaneous interventional radiology?","authors":"Maxime Barat , Laurent Milot","doi":"10.1016/j.diii.2024.01.007","DOIUrl":"10.1016/j.diii.2024.01.007","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 6","pages":"Pages 209-210"},"PeriodicalIF":5.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139974096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baptiste Bonnet , Thierry de Baère , Paul Beunon , Adlane Feddal , Lambros Tselikas , Frédéric Deschamps
{"title":"Robotic-assisted CT-guided percutaneous thermal ablation of abdominal tumors: An analysis of 41 patients","authors":"Baptiste Bonnet , Thierry de Baère , Paul Beunon , Adlane Feddal , Lambros Tselikas , Frédéric Deschamps","doi":"10.1016/j.diii.2024.01.005","DOIUrl":"10.1016/j.diii.2024.01.005","url":null,"abstract":"<div><h3>Purpose</h3><p>Robotic assistance is rapidly evolving and may help physicians optimize needle guidance during percutaneous interventions. The purpose of the study was to report feasibility, safety, accuracy, immediate clinical success and short-term local tumor control after robotic-assisted computed tomography (CT)-guided thermal ablation of abdominal tumors.</p></div><div><h3>Materials and methods</h3><p>Forty-one patients who underwent percutaneous thermal ablation of abdominal tumors using robotic-assisted CT-guided were included. All ablations were performed with robotic assistance, using an optically-monitored robotic system with a needle guide sent to preplanned trajectories defined on three-dimensional-volumetric CT acquisitions with respiration monitoring. Endpoints were technical success, safety, distance from needle tip to planned trajectory and number of needle adjustments, and complete ablation rate.</p></div><div><h3>Results</h3><p>Forty-one patients (31 men; mean age, 66.7 ± 9.9 [standard deviation (SD)] years [age range: 41–84 years]) were treated for 48 abdominal tumors, with 79 planned needles. Lesions treated were located in the liver (23/41; 56%), kidney (14/41;34%), adrenal gland (3/41; 7%) or retroperitoneum (1/41; 2%). Technical success was achieved in 39/41 (95%) patients, and 76/79 (96%) needle insertions. The mean lateral distance between the needle tip and planned trajectory was 3.2 ± 4.5 (SD) mm (range: 0–20 mm) before adjustments, and the mean three-dimensional distance was 1.6 ± 2.6 (SD) mm (range: 0–13 mm) after 29 manual depth adjustments (29/78; 37%) and 33 lateral adjustments (33/78; 42%). Two (2/79; 3%) needles required complete manual reinsertion. One grade 3 complication was reported in one patient (1/41; 2%). The overall clinical success rate was 100%. The 3-month local tumor control rate (progression free survival) was 95% (38/41).</p></div><div><h3>Conclusion</h3><p>These results provide further evidence on the use of robotic-assisted needle insertion regarding feasibility, safety, and accuracy, resulting in effective percutaneous thermal ablation of abdominal tumors.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 6","pages":"Pages 227-232"},"PeriodicalIF":5.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211568424000172/pdfft?md5=3540210314c1be55dde8740f2f9d66c3&pid=1-s2.0-S2211568424000172-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139898308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Achille Beysang , Nicolas Villani , Fatma Boubaker , Ulysse Puel , Michael Eliezer , Gabriela Hossu , Karim Haioun , Alain Blum , Pedro Augusto Gondim Teixeira , Cécile Parietti-Winkler , Romain Gillet
{"title":"Ultra-high-resolution CT of the temporal bone: Comparison between deep learning reconstruction and hybrid and model-based iterative reconstruction","authors":"Achille Beysang , Nicolas Villani , Fatma Boubaker , Ulysse Puel , Michael Eliezer , Gabriela Hossu , Karim Haioun , Alain Blum , Pedro Augusto Gondim Teixeira , Cécile Parietti-Winkler , Romain Gillet","doi":"10.1016/j.diii.2024.02.001","DOIUrl":"10.1016/j.diii.2024.02.001","url":null,"abstract":"<div><h3>Purpose</h3><p>The purpose of this study was to evaluate the ability of ultra-high-resolution computed tomography (UHR-CT) to assess stapes and chorda tympani nerve anatomy using a deep learning (DLR), a model-based, and a hybrid iterative reconstruction algorithm compared to simulated conventional CT.</p></div><div><h3>Materials and methods</h3><p>CT acquisitions were performed with a Mercury 4.0 phantom. Images were acquired with a 1024 × 1024 matrix and a 0.25 mm slice thickness and reconstructed using DLR, model-based, and hybrid iterative reconstruction algorithms. To simulate conventional CT, images were also reconstructed with a 512 × 512 matrix and a 0.5 mm slice thickness. Spatial resolution, noise power spectrum, and objective high-contrast detectability were compared. Three radiologists evaluated the clinical acceptability of these algorithms by assessing the thickness and image quality of the stapes footplate and superstructure elements, as well as the image quality of the chorda tympani nerve bony and tympanic segments using a 5-point confidence scale on 13 temporal bone CT examinations reconstructed with the four algorithms.</p></div><div><h3>Results</h3><p>UHR-CT provided higher spatial resolution than simulated conventional CT at the penalty of higher noise. DLR and model-based iterative reconstruction provided better noise reduction than hybrid iterative reconstruction, and DLR had the highest detectability index, regardless of the dose level. All stapedial structure thicknesses were thinner using UHR-CT by comparison with conventional simulated CT (<em>P</em> < 0.009). DLR showed the best visualization scores compared to the other reconstruction algorithms (<em>P</em> < 0.032).</p></div><div><h3>Conclusion</h3><p>UHR-CT with DLR results in less noise than UHR-CT with hybrid iterative reconstruction and significantly improves stapes and tympanic chorda tympani nerve depiction compared to simulated conventional CT and UHR-CT with iterative reconstruction.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 6","pages":"Pages 233-242"},"PeriodicalIF":5.5,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211568424000366/pdfft?md5=e3ddcd3dea6038967becaee1d307a882&pid=1-s2.0-S2211568424000366-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139898309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Abdominal image quality and dose reduction with energy-integrating or photon-counting detectors dual-source CT: A phantom study","authors":"","doi":"10.1016/j.diii.2024.05.002","DOIUrl":"10.1016/j.diii.2024.05.002","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to assess image-quality and dose reduction potential using a photon-counting computed tomography (PCCT) system by comparison with two different dual-source CT (DSCT) systems using two phantoms.</div></div><div><h3>Materials and methods</h3><div>Acquisitions on phantoms were performed using two DSCT systems (DSCT1 [Somatom Force] and DSCT2 [Somatom Pro.Pulse]) and one PCCT system (Naeotom Alpha) at four dose levels (13/6/3.4/1.8 mGy). Noise power spectrum (NPS) and task-based transfer function (TTF) were computed to assess noise magnitude and noise texture and spatial resolution (f<sub>50</sub>), respectively. Detectability indexes (d’) were computed to model the detection of abdominal lesions: one unenhanced high-contrast task, one contrast-enhanced high-contrast task and one unenhanced low-contrast task. Image quality was subjectively assessed on an anthropomorphic phantom by two radiologists.</div></div><div><h3>Results</h3><div>For all dose levels, noise magnitude values were lower with PCCT than with DSCTs. For all CT systems, similar noise texture values were found at 13 and 6 mGy, but the greatest noise texture values were found for DSCT2 and the lowest for PCCT at 3.4 and 1.8 mGy. For high-contrast inserts, similar or lower f<sub>50</sub> values were found with PCCT than with DSCT1 and the opposite pattern was found for the low-contrast insert. For the three simulated lesions, d’ values were greater with PCCT than with DSCTs. Abdominal images were rated satisfactory for clinical use by the radiologists for all dose levels with PCCT and for 13 and 6 mGy with DSCTs.</div></div><div><h3>Conclusion</h3><div>By comparison with DSCTs, PCCT reduces image-noise and improves detectability of simulated abdominal lesions without altering the spatial resolution and image texture. Image-quality obtained with PCCT seem to indicate greater potential for dose optimization than those obtained with DSCTs.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 379-385"},"PeriodicalIF":4.9,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140959874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The cutting edge: Promising oncology radiotracers in clinical development","authors":"","doi":"10.1016/j.diii.2024.04.004","DOIUrl":"10.1016/j.diii.2024.04.004","url":null,"abstract":"<div><div><span>Molecular imaging moves forward with the development of new imaging agents<span>, and among these are new radiotracers for nuclear medicine applications, particularly positron emission tomography (PET). A number of new targets are becoming accessible for use in oncologic applications. In this review, major new radiotracers in clinical development are discussed. Prominent among these is the family of fibroblast-activation protein-targeted agents that interact with the tumor microenvironment and may show superiority to 2-deoxy-2-[18F]fluoro-</span></span><span>d</span><span>-glucose in a subset of different tumor histologies. Additionally, carbonic anhydrase IX (CAIX) inhibitors are directed at clear cell renal cell carcinoma, which has long lacked an effective PET imaging agent. Those CAIX agents may also have utility in hypoxic tumors. Pentixafor, which binds to a transmembrane receptor, may similarly allow for visualization by PET of low-grade lymphomas, as well as being a second agent for multiple myeloma that opens theranostic possibilities. There are new adrenergic agents aimed at providing a PET-visible replacement to the single-photon-emitting radiotracer meta-[123I]iodobenzylguanidine (MIBG). Finally, in response to a major development in oncologic chemotherapy, there are new radiotracers targeted at assessing the suitability or use of immunotherapeutic agents. All of these and the existing evidence for their utility are discussed.</span></div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 400-406"},"PeriodicalIF":4.9,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiation dose reduction and image quality improvement with ultra-high resolution temporal bone CT using deep learning-based reconstruction: An anatomical study","authors":"","doi":"10.1016/j.diii.2024.05.001","DOIUrl":"10.1016/j.diii.2024.05.001","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to evaluate the achievable radiation dose reduction of an ultra-high resolution computed tomography (UHR-CT) scanner using deep learning reconstruction (DLR) while maintaining temporal bone image quality equal to or better than high-resolution CT (HR-CT).</div></div><div><h3>Materials and methods</h3><div>UHR-CT acquisitions were performed with variable tube voltages and currents at eight different dose levels (volumic CT dose index [CTDIvol] range: 4.6–79 mGy), 1024<sup>2</sup> matrix, and 0.25 mm slice thickness and reconstructed using DLR and hybrid iterative reconstruction (HIR) algorithms. HR-CT images were acquired using a standard protocol (120 kV/220 mAs; CTDI vol, 54.2 mGy, 512<sup>2</sup> matrix, and 0.5 mm slice thickness). Two radiologists rated the image quality of seven structures using a five point confidence scale on six cadaveric temporal bone CTs. A global image quality score was obtained for each CT protocol by summing the image quality scores of all structures.</div></div><div><h3>Results</h3><div>With DLR, UHR-CT at 120 kV/220 mAs (CTDIvol, 50.9 mGy) and 140 kV/220 mAs (CTDIvol, 79 mGy) received the highest global image quality scores (4.88 ± 0.32 [standard deviation (SD)] [range: 4–5] and 4.85 ± 0.35 [range: 4–5], respectively; <em>P</em> = 0.31), while HR-CT at 120 kV/220 mAs and UHR-CT at 120 kV/20 mAs received the lowest (<em>i.e</em>., 3.14 ± 0.75 [SD] [range: 2–5] and 2.97 ± 0.86 [SD] [range: 1–5], respectively; <em>P</em> = 0.14). All the DLR protocols had better image quality scores than HR-CT with HIR.</div></div><div><h3>Conclusion</h3><div>UHR-CT with DLR can be performed with up to a tenfold reduction in radiation dose compared to HR-CT with HIR while maintaining or improving image quality.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 371-378"},"PeriodicalIF":4.9,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}