Charles Roux , Romain Chauvet , Farha Tessier , Louis Meyblum , Jonathan Cortese , Maxime Baudouin , Fan Sun , Graciela Pavon-Djavid , Yun Luo , Claire Mangeney , Geraud Forestier , Frederic Clarencon , Aymeric Rouchaud
{"title":"Bioresorbable scaffolds in interventional radiology: Current concepts and future direction","authors":"Charles Roux , Romain Chauvet , Farha Tessier , Louis Meyblum , Jonathan Cortese , Maxime Baudouin , Fan Sun , Graciela Pavon-Djavid , Yun Luo , Claire Mangeney , Geraud Forestier , Frederic Clarencon , Aymeric Rouchaud","doi":"10.1016/j.diii.2025.11.001","DOIUrl":"10.1016/j.diii.2025.11.001","url":null,"abstract":"<div><div>Remarkable progress has been made in the endovascular management of atherosclerotic lesions in recent decades. Despite initial challenges, such as arterial dissection and acute thrombosis, successive technological innovations have led to the development of stents designed to minimize the risk of restenosis and occlusion. Percutaneous transluminal angioplasty, combined with antiplatelet regimens and management of cardiovascular risk factors, is now at the forefront of symptomatic arteriosclerotic lesion treatment. However, a persistent limitation of percutaneous transluminal angioplasty is the permanent implantation of metallic stents. The long-term presence of metallic stents requires prolonged antiplatelet therapy, creates artifacts on imaging, and is associated with late or very late stent failure. All these conditions are linked to significant morbidity and mortality. The purpose of this review was to provide interventional practitioners with a comprehensive overview of the need for bioresorbable stents in interventional radiology practice by briefly reviewing the vascular healing process, and the factors contributing to stent failure, including patient- and stent-related factors, and by exploring the emergence of bioresorbable stents as the next frontier in endovascular therapy. This article illustrates and discusses how bioresorbable scaffolds could transform the landscape of endovascular interventional radiology from head to toe by retracing the major milestones in bioresorbable scaffold development, outlining future technical improvements, and highlighting current clinical evidence and future perspectives.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"107 3","pages":"Pages 91-102"},"PeriodicalIF":8.1,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145565928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guillaume Chassagnon , Rafael Marini , Valentin Ong , Jennifer Da Silva , Denis Habip Gatenyo , Isabelle Honore , Reem Kanaan , Nicolas Carlier , Johanna Fesenbeckh , Espérie Burnet , Marie-Pierre Revel , Clémence Martin , Pierre-Régis Burgel
{"title":"Identification of structural predictors of lung function improvement in adults with cystic fibrosis treated with elexacaftor-tezacaftor-ivacaftor using deep-learning","authors":"Guillaume Chassagnon , Rafael Marini , Valentin Ong , Jennifer Da Silva , Denis Habip Gatenyo , Isabelle Honore , Reem Kanaan , Nicolas Carlier , Johanna Fesenbeckh , Espérie Burnet , Marie-Pierre Revel , Clémence Martin , Pierre-Régis Burgel","doi":"10.1016/j.diii.2025.09.003","DOIUrl":"10.1016/j.diii.2025.09.003","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to evaluate the relationship between structural abnormalities on CT and lung function prior to and after initiation of elexacaftor-tezacaftor-ivacaftor (ETI) in adults with cystic fibrosis (CF) using a deep learning model.</div></div><div><h3>Materials and methods</h3><div>A deep learning quantification model was developed using 100 chest computed tomography (CT) examinations of patients with CF and 150 chest CT examinations of patients with various other bronchial diseases to quantify seven types of abnormalities. This model was then applied to an independent dataset of CT examinations of 218 adults with CF who were treated with ETI. The relationship between structural abnormalities and percent predicted forced expiratory volume in one second (ppFEV<sub>1</sub>) was examined using general linear regression models.</div></div><div><h3>Results</h3><div>The deep learning model performed as well as radiologists for the quantification of the seven types of abnormalities. Chest CT examinations obtained before to and one year after the initiation of ETI were analyzed. The independent structural predictors of ppFEV<sub>1</sub> prior to ETI were bronchial wall thickening (<em>P</em> = 0.011), mucus plugging (<em>P</em> < 0.001), consolidation/atelectasis (<em>P</em> < 0.001), and mosaic perfusion (<em>P</em> < 0.001). An increase in ppFEV<sub>1</sub> after initiation of ETI independently correlated with a decrease in bronchial wall thicknening (-49 %; <em>P</em> = 0.004), mucus plugging (-92 %; <em>P</em> < 0.001), centrilobular nodules (-78 %; <em>P</em> = 0.009) and mosaic perfusion (-14 %; <em>P</em> < 0.001). Younger age (<em>P</em> < 0.001), greater mucus plugging extent (<em>P</em> = 0.016), and centrilobular nodules (<em>P</em> < 0.001) prior to ETI initiation were independent predictors of ppFEV<sub>1</sub> improvement.</div></div><div><h3>Conclusion</h3><div>A deep learning model can quantify CT lung abnormalities in adults with CF. Lung function impairment in adults with CF is associated with muco-inflammatory lesions on CT, which are largely reversible with ETI, and with mosaic perfusion, which appear less reversible and is presumably related to irreversible damage. Predictors of lung function improvement are a younger age and a greater extent of muco-inflammatory lesions obstructing the airways.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"107 2","pages":"Pages 62-72"},"PeriodicalIF":8.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breast cancer imaging without gadolinium-based contrast agent: A review of current applications and future trends","authors":"Maya Honda , Mami Iima , Masako Kataoka , Daiju Ueda , Tsukasa Saida , Kentaro Nishioka , Ryo Kurokawa , Satoru Ide , Masahiro Yanagawa , Tadashi Watabe , Kenji Hirata , Rintaro Ito , Seitaro Oda , Koji Takumi , Mariko Kawamura , Shunsuke Sugawara , Keitaro Sofue , Akihiko Sakata , Shinji Naganawa","doi":"10.1016/j.diii.2025.10.004","DOIUrl":"10.1016/j.diii.2025.10.004","url":null,"abstract":"<div><div>Dynamic contrast-enhanced magnetic resonance imaging remains a cornerstone of breast cancer diagnosis, yet concerns regarding the safety, environmental impact, and cost of gadolinium-based contrast agents are driving the development of gadolinium-based contrast agent-free alternatives. This review outlines emerging non-contrast imaging modalities that support a more sustainable approach to breast cancer diagnosis. Advanced MRI techniques, such as diffusion-weighted imaging and synthetic MRI, provide detailed tissue characterization without the need for contrast agents. In computed tomography (CT), innovations including dual-energy CT and photon-counting detector CT are improving lesion detection and characterization, with photon-counting detector CT offering exceptional spatial resolution. Molecular imaging with positron emission tomography is also advancing beyond <sup>18</sup>F-fluorodeoxyglucose, incorporating dedicated high-resolution systems and novel tracers targeting specific biomarkers, such as 16α-<sup>18</sup>F-fluoro-17β-estradiol for estrogen receptors, fibroblast activation protein inhibitors, and human epidermal growth factor receptor 2–targeted agents. The future of breast imaging is likely to adopt a multimodal strategy, combining these innovations to deliver more accurate, personalized, and sustainable patient care.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"107 2","pages":"Pages 51-61"},"PeriodicalIF":8.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145477119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Romain Gillet , Samy Obeid , Maxime Clara , Gabriela Hossu , Khalid Ambarki , Fatma Boubaker , Pedro Augusto Gondim Teixeira , Alain Blum
{"title":"Diagnostic performance of pelvic CT, T1-weighted MRI and mineralized-tissue MRI for the assessment of structural lesions in sacroiliitis in patients with axial spondyloarthritis","authors":"Romain Gillet , Samy Obeid , Maxime Clara , Gabriela Hossu , Khalid Ambarki , Fatma Boubaker , Pedro Augusto Gondim Teixeira , Alain Blum","doi":"10.1016/j.diii.2025.09.004","DOIUrl":"10.1016/j.diii.2025.09.004","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to evaluate the diagnostic capability of mineralized tissue-magnetic resonance imaging (MT-MRI) to detect erosions, sclerosis, and ankylosis of the sacroiliac joint (SIJ) in patients with axial spondyloarthritis, by comparison with T1-weighted MRI and pelvic computed tomography (CT), using SIJ CT as the standard of reference.</div></div><div><h3>Material and methods</h3><div>This retrospective study included 100 patients (62 women, 38 men; mean age, 39.9 ± 14.3 [standard deviation] years; age range: 19–79) with suspected axial spondyloarthritis, who underwent SIJ MRI and CT on the same day between August 2023 and March 2025. Two musculoskeletal radiologists independently scored the amount of structural lesions of SIJs. The diagnostic confidence in each imaging modality was also evaluated.</div></div><div><h3>Results</h3><div>The erosion scores showed no significant difference between SIJ CT and MT-MRI for both readers (<em>P</em> ≥ 0.07) but were lower than those of SIJ CT when using T1-weighted MRI for both readers (<em>P</em> ≤ 0.011). The performance of pelvic CT for depicting erosion was intermediate but closer to that of MT-MRI. The sclerosis scores were 16–20 % lower with T1-weighted MRI than with SIJ CT (<em>P</em> ≤ 0.012) and 3 % lower with MT-MRI (<em>P</em> ≤ 0.04), but 8 % overestimated using pelvic CT (<em>P</em> ≤ 0.001). For both groups, SIJ CT obtained the highest confidence score, which was superior to pelvic CT (<em>P</em> ≤ 0.001), itself superior to T1-weighted MRI and MT-MRI (<em>P</em> ≤ 0.001), with the latter two not differing significantly (<em>P</em> ≥ 0.109).</div></div><div><h3>Conclusion</h3><div>T1-weighted MRI alone is insufficient for reliably evaluating structural lesions of SIJs due to sacroiliitis in patients with axial spondyloarthritis. MT-MRI emerges as the closest alternative to SIJ CT, demonstrating excellent diagnostic performance while eliminating radiation exposure.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"107 2","pages":"Pages 73-82"},"PeriodicalIF":8.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chiara Pozzessere , Paul Habert , Mathieu Lederlin
{"title":"From voxel to treatment response: Rethinking the role of imaging in cystic fibrosis in the era of artificial intelligence","authors":"Chiara Pozzessere , Paul Habert , Mathieu Lederlin","doi":"10.1016/j.diii.2025.10.009","DOIUrl":"10.1016/j.diii.2025.10.009","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"107 2","pages":"Pages 47-48"},"PeriodicalIF":8.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145477160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mineralized-tissue MRI: A new standard for sacroiliac joint imaging","authors":"Marie-Pauline Talabard , Marie Faruch-Bilfeld","doi":"10.1016/j.diii.2025.10.006","DOIUrl":"10.1016/j.diii.2025.10.006","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"107 2","pages":"Pages 45-46"},"PeriodicalIF":8.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145446401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marie Pauline Talabard , Virginie Audard , David Biau
{"title":"CT and MR imaging features of periosteal chondrosarcoma","authors":"Marie Pauline Talabard , Virginie Audard , David Biau","doi":"10.1016/j.diii.2025.12.004","DOIUrl":"10.1016/j.diii.2025.12.004","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"107 2","pages":"Pages 83-84"},"PeriodicalIF":8.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Breast MR imaging without gadolinium-based contrast agents: A visionary goal or scientific mirage?","authors":"Toulsie Ramtohul","doi":"10.1016/j.diii.2025.11.004","DOIUrl":"10.1016/j.diii.2025.11.004","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"107 2","pages":"Pages 49-50"},"PeriodicalIF":8.1,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145565896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}