{"title":"More evidence to support greater use of 4D flow cardiac MRI","authors":"David A Bluemke , Nadine Kawel-Boehm","doi":"10.1016/j.diii.2024.02.014","DOIUrl":"10.1016/j.diii.2024.02.014","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 7","pages":"Pages 245-246"},"PeriodicalIF":4.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140066020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improved image quality and abdominal lesion detection with photon-counting CT compared to dual-source CT: New evidence from a phantom study","authors":"","doi":"10.1016/j.diii.2024.06.008","DOIUrl":"10.1016/j.diii.2024.06.008","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 349-350"},"PeriodicalIF":4.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141493942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dual-energy CT: Bridging the gap between innovation and clinical practice","authors":"Paul Calame , Sébastien Mulé","doi":"10.1016/j.diii.2024.02.011","DOIUrl":"10.1016/j.diii.2024.02.011","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 7","pages":"Pages 247-248"},"PeriodicalIF":4.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140068822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The potential and pitfalls of ChatGPT in radiology","authors":"Augustin Lecler , Philippe Soyer , Bo Gong","doi":"10.1016/j.diii.2024.05.003","DOIUrl":"10.1016/j.diii.2024.05.003","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 7","pages":"Pages 249-250"},"PeriodicalIF":4.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141177184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jan M. Brendel , Jonathan Walterspiel , Florian Hagen , Jens Kübler , Jean-François Paul , Konstantin Nikolaou , Meinrad Gawaz , Simon Greulich , Patrick Krumm , Moritz Winkelmann
{"title":"Coronary artery disease evaluation during transcatheter aortic valve replacement work-up using photon-counting CT and artificial intelligence","authors":"Jan M. Brendel , Jonathan Walterspiel , Florian Hagen , Jens Kübler , Jean-François Paul , Konstantin Nikolaou , Meinrad Gawaz , Simon Greulich , Patrick Krumm , Moritz Winkelmann","doi":"10.1016/j.diii.2024.01.010","DOIUrl":"10.1016/j.diii.2024.01.010","url":null,"abstract":"<div><h3>Purpose</h3><p>The purpose of this study was to evaluate the capabilities of photon-counting (PC) CT combined with artificial intelligence-derived coronary computed tomography angiography (PC-CCTA) stenosis quantification and fractional flow reserve prediction (FFRai) for the assessment of coronary artery disease (CAD) in transcatheter aortic valve replacement (TAVR) work-up.</p></div><div><h3>Materials and methods</h3><p>Consecutive patients with severe symptomatic aortic valve stenosis referred for pre-TAVR work-up between October 2021 and June 2023 were included in this retrospective tertiary single-center study. All patients underwent both PC-CCTA and ICA within three months for reference standard diagnosis. PC-CCTA stenosis quantification (at 50% level) and FFRai (at 0.8 level) were predicted using two deep learning models (CorEx, Spimed-AI). Diagnostic performance for global CAD evaluation (at least one significant stenosis ≥ 50% or FFRai ≤ 0.8) was assessed.</p></div><div><h3>Results</h3><p>A total of 260 patients (138 men, 122 women) with a mean age of 78.7 ± 8.1 (standard deviation) years (age range: 51–93 years) were evaluated. Significant CAD on ICA was present in 126/260 patients (48.5%). Per-patient sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were 96.0% (95% confidence interval [CI]: 91.0–98.7), 68.7% (95% CI: 60.1–76.4), 74.3 % (95% CI: 69.1–78.8), 94.8% (95% CI: 88.5–97.8), and 81.9% (95% CI: 76.7–86.4) for PC-CCTA, and 96.8% (95% CI: 92.1–99.1), 87.3% (95% CI: 80.5–92.4), 87.8% (95% CI: 82.2–91.8), 96.7% (95% CI: 91.7–98.7), and 91.9% (95% CI: 87.9–94.9) for FFRai. Area under the curve of FFRai was 0.92 (95% CI: 0.88–0.95) compared to 0.82 for PC-CCTA (95% CI: 0.77–0.87) (<em>P</em> < 0.001). FFRai-guidance could have prevented the need for ICA in 121 out of 260 patients (46.5%) <em>vs.</em> 97 out of 260 (37.3%) using PC-CCTA alone (<em>P</em> < 0.001).</p></div><div><h3>Conclusion</h3><p>Deep learning-based photon-counting FFRai evaluation improves the accuracy of PC-CCTA ≥ 50% stenosis detection, reduces the need for ICA, and may be incorporated into the clinical TAVR work-up for the assessment of CAD.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 7","pages":"Pages 273-280"},"PeriodicalIF":4.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211568424000354/pdfft?md5=08a79564cba5d15db35d4e6c9db76424&pid=1-s2.0-S2211568424000354-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139898307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xue Wang , Lijuan Wang , Yating Wu , Xiang Lv , Yao Xu , Weiqiang Dou , Hongying Zhang , Jingtao Wu , Song'an Shang
{"title":"Intracerebral hemodynamic abnormalities in patients with Parkinson's disease: Comparison between multi-delay arterial spin labelling and conventional single-delay arterial spin labelling","authors":"Xue Wang , Lijuan Wang , Yating Wu , Xiang Lv , Yao Xu , Weiqiang Dou , Hongying Zhang , Jingtao Wu , Song'an Shang","doi":"10.1016/j.diii.2024.01.006","DOIUrl":"10.1016/j.diii.2024.01.006","url":null,"abstract":"<div><h3>Purpose</h3><p>The purpose of this study was to analyze the intracerebral abnormalities of hemodynamics in patients with Parkinson's disease (PD) through arterial spin labelling (ASL) technique with multi-delay ASL (MDASL) and conventional single-delay ASL (SDASL) protocols and to verify the potential clinical application of these features for the diagnosis of PD.</p></div><div><h3>Materials and methods</h3><p>Perfusion data of the brain obtained using MDASL and SDASL in patients with PD were compared to those obtained in healthy control (HC) subjects. Intergroup comparisons of z-scored cerebral blood flow (zCBF), arterial transit time (zATT) and cerebral blood volume (zCBV) were performed via voxel-based analysis. Performance of these perfusion metrics were estimated using area under the receiver operating characteristic curve (AUC) and compared using Delong test.</p></div><div><h3>Results</h3><p>A total of 47 patients with PD (29 men; 18 women; mean age, 69.0 ± 7.6 (standard deviation, [SD]) years; range: 50.0−84.0 years) and 50 HC subjects (28 men; 22 women; mean age, 70.1 ± 6.2 [SD] years; range: 50.0−93.0 years) were included. Relative to the uncorrected-zCBF map, the corrected-zCBF map further refined the distributed brain regions in the PD group versus the HC group, manifested as the extension of motor-related regions (<em>P</em><sub>FWE</sub> < 0.001). Compared to the HC subjects, patients with PD had elevated zATT and zCBV in the right putamen, a shortened zATT in the superior frontal gyrus, and specific zCBV variations in the left precuneus and the right supplementary motor area (<em>P</em><sub>FWE</sub> < 0.001). The corrected-zCBF (AUC, 0.90; 95% confidence interval [CI]: 0.84−0.96) showed better classification performance than uncorrected-zCBF (AUC, 0.84; 95% CI: 0.75−0.92) (<em>P</em> = 0.035). zCBV achieved an AUC of 0.89 (95% CI: 0.82−0.96) and zATT achieved an AUC of 0.66 (95% CI: 0.55−0.77). The integration model of hemodynamic features from MDASL provided improved performance (AUC, 0.97; 95% CI: 0.95−0.98) for the diagnosis of PD by comparison with each perfusion model (<em>P</em> < 0.001).</p></div><div><h3>Conclusion</h3><p>ASL identifies impaired hemodynamics in patients with PD including regional abnormalities of CBF, CBV and ATT, which can better be mapped with MDASL compared to SDASL. These findings provide complementary depictions of perfusion abnormalities in patients with PD and highlight the clinical feasibility of MDASL.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 7","pages":"Pages 281-291"},"PeriodicalIF":4.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139680227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chang-Hui Xiao , Peng Liu , Hui-Hui Zhang , Fan Yang , Xiang Chen , Feng Huang , Jian-bin Liu , Xian-Zheng Tan
{"title":"Incremental diagnostic value of virtual non-contrast dual-energy CT for the diagnosis of choledocholithiasis over conventional unenhanced CT","authors":"Chang-Hui Xiao , Peng Liu , Hui-Hui Zhang , Fan Yang , Xiang Chen , Feng Huang , Jian-bin Liu , Xian-Zheng Tan","doi":"10.1016/j.diii.2024.02.004","DOIUrl":"10.1016/j.diii.2024.02.004","url":null,"abstract":"<div><h3>Purpose</h3><p>The purpose of this study was to evaluate the incremental diagnostic value of virtual non-contrast (VNC) images derived from unenhanced dual-energy computed tomography (CT) for the diagnosis of choledocholithiasis by comparison with conventional unenhanced CT.</p></div><div><h3>Materials and methods</h3><p>Eighty-nine patients with gallbladder stones who had undergone both abdominal unenhanced dual-energy CT and magnetic resonance cholangiopancreatography (MRCP) were retrospectively included. There were 53 men and 36 women, with a mean age of 54 ± 13 (standard deviation) years (age range: 41–67 years). VNC and conventional CT images were generated. Two independent radiologists evaluated the presence of choledocholithiasis in three reading sessions (session 1, conventional unenhanced CT images; session 2, VNC images; session 3, conventional unenhanced CT plus VNC images). The reading time to identify choledocholithiasis was recorded. Inter-reader agreement was measured by using the Cohen kappa (κ) test. Incremental diagnostic value of VNC imaging when combined with conventional unenhanced CT was assessed based on discrimination (area under the curve [AUC]) and clinical utility (decision curve analysis). The diagnostic performance of dual-energy CT and that of MRCP were compared using DeLong test.</p></div><div><h3>Results</h3><p>Using the standard of reference, 39 patients (39/89; 44%) had choledocholithiasis. The diagnosis of choledocholithiasis was improved using VNC images in combination with conventional unenhanced CT (AUC, 0.877; 95% confidence interval [CI]: 0.808, 0.947) by comparison with conventional unenhanced CT alone (AUC, 0.789; 95% CI: 0.718, 0.877) (<em>P</em> = 0.033) and achieved almost perfect inter-reader agreement (κ = 0.88; 95% CI: 0.72, 1.00) for the diagnosis of choledocholithiasis, without lengthening the median reading time (16.2 s for the combination of conventional CT and VNC images <em>vs.</em> 14.7 s for conventional CT alone; <em>P</em> <em>=</em> 0<em>.</em>325). Based on decision curve analysis, adding VNC imaging to conventional unenhanced CT resulted in a higher net benefit among most of decision thresholds. No differences in diagnostic performance were found between the combination of conventional unenhanced CT and VNC imaging (AUC, 0.877; 95% CI: 0.808, 0.947) and MRCP (AUC, 0.913; 95% CI: 0.852, 0.974) (<em>P</em> <em>=</em> 0<em>.</em>458).</p></div><div><h3>Conclusions</h3><p>VNC images derived from dual-energy unenhanced CT have incremental diagnostic value for the diagnosis of choledocholithiasis. Unenhanced CT in a dual-energy mode may be a useful tool for the diagnosis of choledocholithiasis.</p></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 7","pages":"Pages 292-298"},"PeriodicalIF":4.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2211568424000391/pdfft?md5=4c5706cf63ae66a8b87affdf7553a8ee&pid=1-s2.0-S2211568424000391-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139913800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The trade-off dilemma between radiation dose and image resolution","authors":"","doi":"10.1016/j.diii.2024.06.006","DOIUrl":"10.1016/j.diii.2024.06.006","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 351-352"},"PeriodicalIF":4.9,"publicationDate":"2024-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Next-generation oncology radiotracers for a promising personalized medicine","authors":"","doi":"10.1016/j.diii.2024.06.003","DOIUrl":"10.1016/j.diii.2024.06.003","url":null,"abstract":"","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 347-348"},"PeriodicalIF":4.9,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Apparent diffusion coefficient analysis of solid tissue helps distinguish borderline from invasive malignant adnexal masses rated O-RADS MRI 4","authors":"","doi":"10.1016/j.diii.2024.05.004","DOIUrl":"10.1016/j.diii.2024.05.004","url":null,"abstract":"<div><h3>Purpose</h3><div>The purpose of this study was to evaluate the contribution of apparent diffusion coefficient (ADC) analysis of the solid tissue of adnexal masses to optimize tumor characterization and possibly refine the risk stratification of the O-RADS MRI 4 category.</div></div><div><h3>Materials and methods</h3><div>The EURAD cohort was retrospectively analyzed to select all patients with an adnexal mass with solid tissue and feasible ADC measurements. Two radiologists independently measured the ADC values of solid tissue, excluding necrotic areas, surrounding structures, and magnetic susceptibility artifacts. Significant differences in diffusion quantitative parameters in the overall population and according to the morphological aspect of solid tissue were analyzed to identify its impact on ADC reliability. Receiver operating characteristics curve (ROC) was used to determine the optimum cutoff of the ADC for distinguishing invasive from non-invasive tumors in the O-RADS MRI score 4 population.</div></div><div><h3>Results</h3><div>The final study population included 180 women with a mean age of 57 ± 15.5 (standard deviation) years; age range: 19–95 years) with 93 benign, 23 borderline, and 137 malignant masses. The median ADC values of solid tissue was greater in borderline masses (1.310 × 10<sup>−3</sup> mm<sup>2</sup>/s (Q1, Q3: 1.152, 1.560 × 10<sup>−3</sup> mm<sup>2</sup>/s) than in benign masses (1.035 × 10<sup>−3</sup> mm<sup>2</sup>/s; Q1, Q3: 0.900, 1.560 × 10<sup>−3</sup> mm<sup>2</sup>/s) (<em>P</em> <em>=</em> 0.002) and in benign tumors compared by comparison with invasive masses (0.850 × 10<sup>−3</sup> mm<sup>2</sup>/s; Q1, Q3: 0.750, 0.990 × 10<sup>−3</sup> mm<sup>2</sup>/s) (<em>P</em> < 0.001). Solid tissue corresponded to irregular septa or papillary projection in 18.6% (47/253), to a mural nodule or a mixed mass in 46.2% (117/253), and to a purely solid mass in 35.2% (89/253) of adnexal masses. In mixed masses or masses with mural nodule subgroup, invasive masses had a significantly lower ADC (0.830 × 10<sup>−3</sup> mm<sup>2</sup>/s (Q1, Q3: 0.738, 0.960) than borderline (1.385; Q1, Q3: 1.300, 1.930) (<em>P</em> <em>=</em> 0.0012) and benign masses (<em>P</em> <em>=</em> 0.04). An ADC cutoff of 1.08 × 10<sup>−3</sup> mm<sup>2</sup>/s yielded 71.4% sensitivity and 100% specificity for identifying invasive lesions in the mixed or mural nodule subgroup with an AUC of 0.92 (95% confidence interval: 0.76–0.99).</div></div><div><h3>Conclusion</h3><div>ADC analysis of solid tissue of adnexal masses could help distinguish invasive masses within the O-RADS MRI 4 category, especially in mixed masses or those with mural nodule.</div></div>","PeriodicalId":48656,"journal":{"name":"Diagnostic and Interventional Imaging","volume":"105 10","pages":"Pages 386-394"},"PeriodicalIF":4.9,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141327992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}